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| 1 | Rapamycin attenuates bleomycin-induced pulmonary fibrosis in rats and the expression of metalloproteinase-9 and tissue inhibitors of metalloproteinase-1 in lung tissue显示文摘 | Jin Xiaoguang | 2014 | Chinese Medical Journal2014，，7： | 20 |
| 2 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018，61，12： | 19 |
| 3 | Impending HRT wave precursors to the Wenchuan M_s8.0 earthquake and methods of earthquake impending prediction by using HRT wave显示文摘We deployed four geo-electric monitoring stations in Sichuan and Yunnan provinces from 2004, using the new generation of equipment (PS-100) and technologies to capture the HRT wave earthquake precursor. Before the Wenchuan Ms8.0 earthquake, we recorded the HRT wave precursor at the only operating station in Hongge (HG, Δ=465 km) and found that significant impending signal had been recorded at the station in the early morning ( 0―5 am) of 12th of May, 2008. The precursor for this earthquake is consistent with precursors recorded for other strong earthquakes. The measured physical properties (geo-resistivity and telluric-current) show tidal wave period oscillations from several days to several months before the earthquakes and the amplitude of such HT oscillation increases significantly towards the occurrence of an earthquake. These HT and RT waves from the epicenter have a causal relationship with the earthquakes that happened several days later. The arrival time of two RT waves is proportional to the distance from the station to the epicenter. The estimated natural decay of the amplitude is correlated with the natural period (T0) of the earthquake fault, which is proportional to the fault length. From this relationship, we can predict the earthquake magnitude. For magnitude 6―9 earthquakes, the natural period is about 1―6 hours. Such oscillation comes from the epicenter area and they can propagate several thousand kilometers in the Earth's crust. Before a strong earthquake in the shallow crust, the conductive pore fluid will experience major changes before the fault rapture. Such fluid change will emit an oscillation in the pore fluid pressure. This is the mechanism for the HRT wave generation. Since the China Earthquake Administration funded the HRT wave short-term earth-quake prediction project in 2003, the first record of HRT precursor wave has been recorded from the 2004-12-26 Sumatra Mw9.0 earthquake with the largest epicentre distance Δ=2900 km. Thereafter, we have captured HRT waves from more than twenty strong earthquakes, which are well-matched and show repeatability, consistency and regularity. All our observation with the HRT waves demonstrate that HRT wave precursors to earthquakes indeed exist. Strong earthquakes can be predicted and short-term and impending earthquake prediction is achievable in the very near future. From all the observations, including the ones at HG station from Wenchuan Ms8.0 earthquake, we conclude that using HRT wave to predict earthquakes is feasible. | QIAN FuYe ZHAO BiRu QIAN Wei ZHAO Jian HE ShiGen ZHANG HongKui LI ShiYu LI ShaoKun YAN GuLiang WANG ChengMin SUN ZhenKai ZHANG DongNing LU Jun ZHANG Ping YANG GuoJun SUN JiaLin GUO ChunSheng TANG YuXiong XU JianMing XIA KunTao JU Hang YIN BangHong LI Ming YANG DongSheng QI WeiLuo HE TaiMing GUAN HuaPing ZHAO YuLin | 2009 | Science China Earth Sciences2009，52，10： | 8 |
| 4 | Extracorporeal blood therapy in sepsis and acute respiratory distress syndrome: the "purifying dream"显示文摘 | Xu Xuefeng Dai Huaping Jia Chun'e Wang Chen | 2014 | Chinese Medical Journal2014，，24： | 6 |
| 5 | Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a novel model of obesity and puberty显示文摘童年肥胖和肥胖相关的新陈代谢的复杂并发症被一本高脂肪的出生后的食谱导致。然而,一个合适的动物模型的缺乏在肥胖研究仍然是可观的挑战。在当前的学习,我们在断奶以后在哺乳期间并且到小狗提供了高脂肪的饮食(HFD ) 给水坝。我们也与导致 HFD 的出生后的肥胖开发了 C57BL/6J 老鼠小狗的一个新奇模型。结果证明用 HFD 喂在小狗导致胖免职和肥胖。而且, HFD 更 potently 比女小狗增加了男性的身体重量(BW ) 。喂 HFD 的女小狗是肥胖的,经历了早熟的发身,并且显示出在视下丘的增加的 kisspeptin 表示。然而,父母肥胖和早熟的发身没在导致 HFD 的出生后的重量获得和小狗的发身发作上施加 synergistic 效果。有趣地,有正常 BW 的一些喂 HFD 的崽也展出了早熟的发身。这发现建议了那篇食谱作文然而并非 BW 扳机发身发作。我们的模型建议肥胖和早熟的发身的好构造有效性。而且,我们的模型能也被用来探索在 dietinduced 之间的相互的相互作用出生后的童年肥胖和发身。 | Rahim Ullah Yan Su Yi Shen Chunlu Li Xiaoqin Xu Jianwei Zhang Ke Huang Naveed Rauf Yang He Jingjing Cheng Huaping Qin Yu-Dong Zhou Junfen Fu | 2017 | Frontiers of Medicine2017，11，2： | 5 |
| 6 | Systematic study on the mechanical and electric behaviors of the nonbuckling interconnect design of stretchable electronics显示文摘Recently, we developed a nonbuckling interconnect design that provides an effective approach to simultaneously achieving high elastic stretchability, easiness for encapsulation, and high electric performance for stretchable electronics. This paper aims to systematically study its mechanical and electric behaviors, including comparisons of the nonbuckling and buckling interconnect designs on stretchability, effects of the thickness on electric performance, and modeling and experimental investigations on the finite deformation mechanics. It is found that the results on stretchability depend on the layouts. Long straight segments and small arc radii for nonbuckling interconnects yield an enhancement of stretchability, which is much better than that of buckling designs. On the other hand, shorter straight segments or thicker interconnects are better to lower the resistances of interconnects.Therefore, optimization of the designs needs to balance the requirements of both the mechanical and electric performances. The finite deformation of interconnects during stretching is analyzed. The established analytic model is well validated by both the finite element modeling and experimental investigations. This work is key for providing the design guidelines for nonbucklingbased stretchable electronics. | Hao Liu RiYe Xue JianQiao Hu XueCheng Ping HuaPing Wu MingQi Huang Han Zhang Xu Guo Rui Li YuLi Chen YeWang Su | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，11： | 3 |
| 7 | Unexpected intercalation-dominated potassium storage in WS2 as a I potassium-ion battery anode显示文摘Unexpected intercalation-dominated process is observed duri ng K^+insertion in WS2 in a voltage range of 0.01-3.0 V.This is different fromthe previously reported two-dimensional(2D)transition metal dichalcogenides that undergo a conversion reaction in a low voltage rangewhen used as anodes in potassium-ion batteries.Charge/discharge processes in the K and Na cells are studied in parallel to demonstrate thedifferention storage mechanisms.The Na^+storage proceeds through intercalation and conversion reactions while the K^+storage is governedby an intercalation reaction.Owing to the reversible K^+intercalation in the van der Waals gaps,the WS2 anode exhibits a low decay rate of 0.07%per cycle,delivering a capacity of 103 mAh·g^-1 after 100 cycles at 100 mA·g^-1.It maintains 57%capacity at 800 mA·g^-1 and shows stablecyclability up to 400 cycles at 500 mA·g^-1.Kinetics study proves the facilitation of K^+transport is derived from the intercalation-dominatedmecha nism.Furthermore,the mechanismis verified by the density functional theory(DFT)calculations,showing that the progressive expansion of the interlayer space can account for the observed results. | Vuhan Wu Yang Xu Yueliang Li Pengbo Lyu Jin Wen Chenglin Zhang Min Zhou Yaoguo Fang Huaping Zhao Ute Kaiser Yong Lei | 2019 | Nano Research2019，12，12： | 3 |
| 8 | Spotlight SAR sparse sampling and imaging method based on compressive sensing显示文摘Spotlight synthetic aperture radar(SAR)emits a chirp signal and the echo bandwidth can be reduced through dechirp processing,where the A/D sampling rate decreases accordingly at the receiver.Compressive sensing allows the compressible signal to be reconstructed with a high probability using only a few samples by solving a linear program problem.This paper presents a novel signal sampling and imaging method for application to spotlight SAR based on compressive sensing.The signal is randomly sampled after dechirp processing to form a low-dimensional sample set,and the dechirp basis is imported to reconstruct the dechirp signal.Matching pursuit(MP)is used as a reconstruction algorithm.The reconstructed signal uses polar format algorithm(PFA)for imaging.Although our novel mechanism increases the system complexity to an extent,the data storage requirements can be compressed considerably.Several simulations verify the feasibility and accuracy of spotlight SAR signal processing via compressive sensing,and the method still obtains acceptable imaging results with 10%of the original echo data. | XU HuaPing YOU YaNan LI ChunSheng ZHANG LvQian | 2012 | Science China(Information Sciences)2012，55，8： | 3 |
| 9 | Interferometric Phase Statistics and Estimation Accuracy of Strong Scatterer for InSAR显示文摘 | XU Huaping LI Shuang FENG Liang | 2012 | Chinese Journal of Electronics2012，21，4： | 3 |
| 10 | Selenium-functionalized metal-organic frameworks as enzyme mimics显示文摘 | Weiqiang Zhou Hongfeng Li Bin Xia Wenlan Ji Shaobo Ji Weina Zhang Wei Huang Fengwei Huo Huaping Xu | 2018 | Nano Research2018，11，10： | 3 |
| 11 | A Novel Decision-level Fusion Segmentation Approach of SAR and Optical Images显示文摘 | XU Huaping WANG Wei LIU Xianghua | 2011 | Chinese Journal of Electronics2011，20，4： | 2 |
| 12 | Selenium containing macrocycles:transformation between Se-N/Se-S/Se-Se bonds显示文摘Macrocycles possess potential applications in supramolecular chemistry and biosystems.Thus development of new kinds of macrocycles is of significance.Herein,novel macrocycles containing Se-Se/Se-S bonds were synthesized via transformation between selenium related dynamic covalent bonds.A monomer containing two ebselen moieties was synthesized(M1).The Se-N bonds in M1 were reduced by dithiothreitol,forming Se-S linked dimer(D1).To realize the transformation from Se-S bonds to Se-Se bonds,guest molecules were added as template,triggering the formation of Se-Se linked dimer(D2).The formation of these two new kinds of macrocycles was determined by ~1H NMR and ^(77)Se NMR,and the necessity of guest molecules was also confirmed.The introduction of ebselen moieties and Se-S bonds or Se-Se bonds into macrocycles may endow it with new responsiveness and bioactivities,as well as new types of host-guest chemistry. | Shaobo Ji Hicham El Mard Mario Smet Wim Dehaen Huaping Xu | 2017 | Science China Chemistry2017，60，9： | 2 |
| 13 | Worst-case tolerance analysis on array antenna based on chaos-genetic algorithm显示文摘This paper studies the effect of amplitude-phase errors on the antenna performance. Via builting on a worst-case error tolerance model, a simple and practical worst error tolerance analysis based on the chaos-genetic algorithm (CGA) is proposed. The proposed method utilizes chaos to optimize initial population for the genetic algorithm (GA) and introduces chaotic disturbance into the genetic mutation, thereby improving the ability of the GA to search for the global optimum. Numerical simulations demonstrate that the accuracy and stability of the worst-case analysis of the proposed approach are superior to the GA. And the proposed algorithm can be used easily for the error tolerant design of antenna arrays. | Hao Yuan Dan Songt Qiangfeng Zhou Huaping Xu | 2012 | Journal of Systems Engineering and Electronics2012，23，6： | 2 |
| 14 | A Novel Wavenumber Domain SAR Imaging Algorithm Based on the Fractional Fourier Transform显示文摘The conventional Wavenumber domain algorithm(WDA) employs Fast Fourier transform(FFT) to implement matched filter. It is characterized by its high precision SAR imaging. Compared with FFT, Fractional Fourier transform(Fr FT) can provide lower and narrower sidelobes when it is applied to compress chirp signals at the optimal transform. This paper proposed a novel SAR imaging algorithm, termed Fr WDA which replaces FFT in WDA with Fr FT. The Fr WDA was derived and its implementation was presented. How to choose the optimal transformation order was given subsequently. The Fr WDA preserves high precision focusing, and has better performance on sidelobe suppression. The Fr WDA is more suitable for the high precision SAR imaging, especially in target detection and recognition. Simulation results demonstrate that Fr WDA provides better performance on focusing and sidelobe suppression compared with the classical FFT-based WDA. | XU Huaping XIAO Zhongyuan GAO Jing LI Chunsheng | 2014 | Chinese Journal of Electronics2014，23，4： | 2 |
| 15 | Bridgman Growth of CdWO4 Single Crystals 显示文摘 | Xiao Huaping Chen Hongbing Xu Fang | 2008 | Journal of Crystal Growth2008，310，3： | 1 |
| 16 | Preparation of BST ferroelectric thin film by pulsed laser ablation for dielectric bolometers显示文摘 | Xu Huaping Zhu Hong Hashimoto K | 2000 | Vacuum2000，59，23： | 1 |
| 17 | Dendritic tellurides acting as antioxidants显示文摘We have described the synthesis of a series of poly(aryl ether) dendrimers with telluride in the core and oligo(ethylene oxide) chains at the pe- riphery which act as glutathione peroxidase (GPx) mimics. These series of compounds were well characterized by H-NMR, 1 13C-NMR and ESI-MS. Using different ROOH (H2O2, cumene hydroperoxide) for testing the antioxidizing properties of these com- pounds, we have found that from generation 0 to 2, the activity of the dendritic GPx mimics first de- creased and then increased. This can be explained on the basis of a greater steric hindrance, going from generation 0 to 1, and stronger binding interactions going from generation 1 to 2. In other words, there exists a balance between binding interactions and steric hindrance that may optimize the GPx activity. | XU Huaping WANG Yapei WANG Zhiqiang LIU Junqiu Mario Smet Wim Dehaen | 2006 | Chinese Science Bulletin2006，51，19： | 1 |
| 18 | Makespan minimization on single batch-processing machine via ant colony optimization显示文摘 | Rui Xu Huaping Chen Xueping Li | 2011 | Computers and Operations Research2011，，3： | 1 |
| 19 | Oil tank detection in synthetic aperture radar images based on quasi-circular shadow and highlighting arcs显示文摘 | XU Huaping CHEN Wei SUN Bing | 2014 | Journal of Applied Remote Sensing2014，8，08： | 1 |
| 20 | 显示文摘 | Xu Huaping Hashimoto K Mukaigawa T | 2000 | Proc SPIE2000，4130，： | 1 |
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