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| 1 | Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-Analysis显示文摘The recent outbreak of COVID-19 has been rapidly spreading on a global scale.To date,there is no specific vaccine against the causative virus,SARS-CoV-2,nor is there an effective medicine for treating COVID-19,thus raising concerns with respect to the effect of risk factors such as clinical course and pathophysiological parameters on disease severity and outcome in patients with COVID-19.By extracting and analyzing all available published clinical data,we identified several major clinical characteristics associated with increased disease severity and mortality among patients with COVID-19.Specifically,preexisting chronic conditions such as hypertension,cardiovascular disease,chronic kidney disease,and diabetes are strongly associated with an increased risk of developing severe COVID-19;surprisingly,however,we found no correlation between chronic liver disease and increased disease severity.In addition,we found that both acute cardiac injury and acute kidney injury are highly correlated with an increased risk of COVID-19-related mortality.Given the high risk of comorbidity and the high mortality rate associated with tissue damage,organ function should be monitored closely in patients diagnosed with COVID-19,and this approach should be included when establishing new guidelines for managing these high-risk patients.Moreover,additional clinical data are needed in order to determine whether a supportive therapy can help mitigate the development of severe,potentially fatal complications,and further studies are needed to identify the pathophysiology and the mechanism underlying this novel coronavirus-associated infectious disease.Taken together,these findings provide new insights regarding clinical strategies for improving the management and outcome of patients with COVID-19. | Xinhui Wang Xuexian Fang Zhaoxian Cai Xiaotian Wu Xiaotong Gao Junxia Min Fudi Wang | 2020 | Research2020，，1： | 13 |
| 2 | Revisiting Scientific Issues for Industrial Applications of Lithium–Sulfur Batteries显示文摘Inspired by high theoretical energy density(-2600 W h kg^(-1))and cost-effectiveness of sulfur cathode,lithium–sulfur batteries are receiving great attention and considered as one of the most promising next-generation high-energy-density batteries.However,over the past decades,the energy density and reliable safety levels as well as the commercial progress of lithium-sulfur batteries are still far from satisfactory due to the disconnection and huge gap between fundamental research and practical application. | Bo Liu Ruyi Fang Dong Xie Wenkui Zhang Hui Huang Yang Xia Xiuli Wang Xinhui Xia Jiangping Tu | 2018 | Energy & Environmental Materials2018，1，4： | 9 |
| 3 | Research on a soft-measurement model of gasification temperature based on recurrent neural network显示文摘Gasification temperature measurement is one of the most challenging tasks in an entrained-flow gasifier and often requires indirect calculation using the soft-sensor method,a parameter prediction method using other parameters that are more easily measurable and using correlation equations that are widely accepted in the gasification field for the temperature data.Machine learning is a non-linear prediction method that can adequately act as a soft sensor.Furthermore,the recurrent neural network(RNN)has the function of memorization,which makes it capable of learning how to deal with temporal order.In this paper,the oxygen-coal ratio,CH_(4)content and CO_(2)content determined through the process analysis of a 3000-t/d coal-water slurry gasifier are used as input parameters for the soft sensor of the gasification temperature.The RNN model and back propagation(BP)neural network model are then established with training-set data from gasification results.Compared with prediction set data from the gasification results,the RNN model is found to be much better than the BP neural network based on important indexes such as the mean square error(MSE),mean absolute error(MAE)and standard deviation(SD).The results show that the MSE of the prediction set of the RNN model is 6.25℃,the MAE is 10.33℃and the SD is 3.88℃,respectively.The overall accuracy,the average accuracy and the stability effects are well within the accepted ranges for the results as such. | Haiquan An Xinhui Fang Zhen Liu Ye Li | 2022 | Clean Energy2022，6，1： | 2 |
| 4 | Recent progress in perovskite solar cells:from device to commercialization显示文摘Perovskite solar cells(PSCs) are undergoing rapid development and the power conversion efficiency reaches 25.7% which attracts increasing attention on their commercialization recently.In this review,we summarized the recent progress of PSCs based on device structures,perovskite-based tandem cells,large-area modules,stability,applications and industrialization.Last,the challenges and perspectives are discussed,aiming at providing a thrust for the commercialization of PSCs in the near future. | Xinhui Luo Xuesong Lin Feng Gao Yang Zhao Xiaodong Li Liqing Zhan Zexiong Qiu Jin Wang Cong Chen Lei Meng Xiaofeng Gao Yu Zhang Zijian Huang Rundong Fan Huifen Liu Yanrun Chen Xiaoxue Ren Jiahong Tang Chun-Hao Chen Dong Yang Yongguang Tu Xiao Liu Dongxue Liu Qing Zhao Jingbi You Junfeng Fang Yongzhen Wu Hongwei Han Xiaodan Zhang Dewei Zhao Fuzhi Huang Huanping Zhou Yongbo Yuan Qi Chen Zhaokui Wang Shengzhong(Frank)Liu Rui Zhu Jotaro Nakazaki Yongfang Li Liyuan Han | 2022 | Science China Chemistry2022，65，12： | 1 |
| 5 | Formation of superhydrophobic boehmite film on glass substrate by sol-gel method显示文摘 | Xinhui Fang Zhijia Yu Xiangyu Sun Xinhua Liu Futao Qin | 2009 | Frontiers of Chemical Engineering in China2009，，1： | 1 |
| 6 | A novel composite coating mesh film for oil-water separartion显示文摘 | Qin Futao Yu Zhijia Fang Xinhui | | 0，，1： | 1 |
| 7 | A novel composite coating mesh film for oil-water separation显示文摘Polytetrafluoroethylene-polyphenylene sulfide composite coating meshfilm was successfully prepared by a simple layered transitional spray-plasticizing method on a stainless steel mesh.It shows super-hydrophobic and super-oleophilic properties.The contact angle of this meshfilm is 156.3°for water,and close to 0°for diesel oil and kerosene.The contact angle hysteresis of water on the meshfilm is 4.3°.The adhesive force between thefilm and substrate is grade 0,theflexibility is 1 mm and the pencil hardness is 4H.An oil-water separation test was car-ried out for oil-contaminated water in a six-stage super-hydrophobicfilm separator.The oil removal rate can reach about 99%. | Futao QIN Zhijia YU Xinhui FANG Xinghua LIU Xiangyu SUN | 2009 | Frontiers of Chemical Science and Engineering2009，3，1： | 0 |
| 8 | Experimental study on dense-phase pneumatic conveying of coal powder at high pressures显示文摘Clean utilization and conversion of coal resources is significant to China’s energy sustainable development.Entrained-flow coal gasification technology is an important method used for clean and efficient conversion of coal.The characteristics and stability of high-pressure dense-phase pneumatic conveying of pulverized coal is crucial to the safe and stable operation of dry-feed entrained-flow coal gasifiers.Dense-phase pneumatic conveying experiments were carried out using a high-volatile bituminous coal in pipes with diameters of 25,15 and 10 mm,respectively,and at back pressures of 1.0-4.0 MPag.The conveying characteristics and effects of operating and structure parameters were studied.Pressure drop models were established for horizontal and vertical upward conveying.The prediction uncertainty was within±30%for the horizontal conveying and±20%for the vertical upward conveying.The relative standard deviation of solid flow rate was proposed to explain conveying stability.The effect of operating parameters on conveying stability was systematically analyzed.The gas velocity-related criterion was proposed for stable conveying. | Qingliang Guan Zhen Liu Xinhui Fang Bing Liu Baozai Peng Ziyang Feng Ya Suo Wenhua Li | 2017 | Clean Energy2017，1，1： | 0 |
| 9 | Composite Eu-MOF@CQDs“off&on”ratiometric luminescent probe for highly sensitive chiral detection of l-lysine and 2-methoxybenzaldehyde显示文摘The high amount of l-lysine can increase the potential risk of cardiovascular disease.Additionally,2-methoxy benzaldehyde(2-MB)has high toxicity and can easily pollute the environment.In this work,carbon quantum dots(CQDs)can be encapsulated into Eu-BTB(H_(3)BTB=1,3,5-tri(4-carboxyphenyl)benzene),forming the multi-emission composite material Eu-BTB@CQDs.It has two emissions peaks(617 nm for Eu and 470 nm for CQDs).Eu-BTB@CQDs can be applied as bi-functional ratiometric“off&on”luminescent sensor for l-lysine and 2-MB with high sensitivity and selectivity,the low limit of detection(LOD)for l-lysine is 3.68μmol/L and for 2-MB is 0.54μmol/L,respectively.Additionally,Eu-BTB@CQDs can quantitatively discriminate l-lysine in the mixed d-and l-lysine water solutions(five different concentrations ratio of l/d-lysine has been set)makes the chiral detection of l-lysine are more meaningful.On the other hand,Eu-BTB@CQDs also can detect 2-MB over 4-methoxybenzaldehyde(4-MB)with high selectivity.Further the detection of 2-MB and l-lysine in the lake water real samples with the reasonable recovery rate.Finally,the detection mechanisms for l-lysine and 2-MB were also investigated and discussed in detail. | Yupeng Jiang Xinhui Fang Ziqing Zhang Xiaomeng Guo Jianzhong Huo Qian Wang Yuanyuan Liu Xinrui Wang Bin Ding | 2023 | Chinese Chemical Letters2023，34，11： | 0 |
| 10 | Achieving 16.68% efficiency ternary as-cast organic solar cells显示文摘State-of-the-art organic solar cells(OSCs)often require the use of high-boiling point additive or post-treatment such as temperature annealing and solvent vapor annealing to achieve the best efficiency.However,additives are not desirable in largescale industrial printing process,while post-treatment also increases the production cost.In this article,we report highly efficient ternary OSCs based on PM6:BTP-Cl Br1:BTP-2O-4Cl-C12(weight ratio=1:1:0.2),with 16.68%power conversion efficiency(PCE)for as-cast device,relatively close to its annealed counterpart(17.19%).Apart from obvious energy tuning effect and complementary absorption spectra,the improved PCE of ternary device is mainly attributed to improved morphological properties including the more favorable materials miscibility,crystallinity,domain size and vertical phase separation,which endorse suppressed recombination.The result of this work provides understanding and guidance for high-performance as-cast OSCs through the ternary strategy. | Ruijie Ma Yang Tao Yuzhong Chen Tao Liu Zhenghui Luo Yuan Guo Yiqun Xiao Jin Fang Guangye Zhang Xiaojun Li Xia Guo Yuanping Yi Maojie Zhang Xinhui Lu Yongfang Li He Yan | 2021 | Science China Chemistry2021，64，4： | 0 |
| 11 | Genetic Architecture of Childhood Kidney and Urological Diseases in China显示文摘Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary component.To delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration system is being imple-mented based on the Chinese Children Genetic Kidney Disease Database(CCGKDD).In this study,all the patients with kidney and urological diseases were recruited from 2014 to 2020.Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features.The genetic diagnosis was confirmed in 883 of 2256(39.1%)patients from 23 provinces in China.Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome(SRNS,23.5%),glomerulonephritis(GN,32.2%),congenital anomalies of the kidney and urinary tract(CAKUT,21.2%),cystic renal disease(3.9%),renal calcinosis/stone(3.6%),tubulopathy(9.7%),and chronic kidney disease of unknown etiology(CKDu,5.8%).The pathogenic variants of 105 monogenetic disorders were identified.Ten distinct genomic disorders were identified as pathogenic copy number variants(CNVs)in 11 patients.The diagnostic yield differed by subgroups,and was highest in those with cystic renal disease(66.3%),followed by tubulopathy(58.4%),GN(57.7%),CKDu(43.5%),SRNS(29.2%),renal calcinosis/stone(29.3%)and CAKUT(8.6%).Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions.We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed.Our data demonstrate the utility of family-based exome sequencing,and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease. | Ye Fang Hua Shi Tianchao Xiang Jiaojiao Liu Jialu Liu Xiaoshan Tang Xiaoyan Fang Jing Chen Yihui Zhai Qian Shen Guomin Li Li Sun Yunli Bi Xiang Wang Yanyan Qian Bingbing Wu Huijun Wang Wenhao Zhou Duan Ma Jianhua Mao Xiaoyun Jiang Shuzhen Sun Ying Shen Xiaorong Liu Aihua Zhang Xiaowen Wang Wenyan Huang Qiu Li Mo Wang Xiaojie Gao Yubin Wu Fang Deng Ruifeng Zhang Cuihua Liu Li Yu Jieqiu Zhuang Qing Sun Xiqiang Dang Haitao Bai Ying Zhu Siguang Lu Bili Zhang Xiaoshan Shao Xuemei Liu Mei Han Lijun Zhao Yuling Liu Jian Gao Ying Bao Dongfeng Zhang Qingshan Ma Liping Zhao Zhengkun Xia Biao Lu Yulong Wang Mengzhun Zhao Jianjiang Zhang Shan Jian Guohua He Huifeng Zhang Bo Zhao Xiaohua LI Feiyan Wang Yufeng Li Hongtao Zhu Xinhui Luo Jinghai Li Jia Rao Hong Xu | 2021 | Phenomics2021，1，3： | 0 |
| 12 | Advanced RF filters for wireless communications显示文摘This paper provides a comprehensive review of advanced radio fre-quency(RF)filter technologies available in miniature chip or inte-grated circuit(IC)form for wireless communication applications.The RF filter technologies were organized according to the time-line of their introduction,in conjunction with each generation of wireless(cellular)communication standards(1G to 5G).This ap-proach enabled a clear explanation of the corresponding invention history,working principles,typical applications and future develop-ment trends.The article covered commercially successful acoustic filter technologies,including the widely used surface acoustic wave(SAW)and bulk acoustic wave(BAW)filters,as well as electromag-netic filter technologies based on low-temperature co-fired ceramic(LTCC)and integrated passive device(IPD).Additionally,emerg-ing filter technologies such as IHP-SAW,suspended thin-film lithium niobate(LiNbO3 or LN)resonant devices and hybrid were also dis-cussed.In order to achieve higher performance,smaller form factor and lower cost for the wireless communication industry,it is believed that fundamental breakthroughs in materials and fabrication tech-niques are necessary for the future development of RF filters. | Kai Yang Chenggong He Jiming Fang Xinhui Cui Haiding Sun Yansong Yang Chengjie Zuo | 2023 | Chip2023，2，4： | 0 |
| 13 | RcSPL1-RcTAF15b regulates the flowering time of rose (Rosa chinensis)显示文摘Rose(Rosa chinensis),which is an economically valuable floral species worldwide,has three types,namely once-flowering(OF),occasional or re-blooming(OR),and recurrent or continuous flowering(CF).However,the mechanism underlying the effect of the age pathway on the duration of the CF or OF juvenile phase is largely unknown.In this study,we observed that the RcSPL1 transcript levels were substantially upregulated during the floral development period in CF and OF plants.Additionally,accumulation of RcSPL1 protein was controlled by rch-miR156.The ectopic expression of RcSPL1 in Arabidopsis thaliana accelerated the vegetative phase transition and flowering.Furthermore,the transient overexpression of RcSPL1 in rose plants accelerated flowering,whereas silencing of RcSPL1 had the opposite phenotype.Accordingly,the transcription levels of floral meristem identity genes(APETALA1,FRUITFULL,and LEAFY)were significantly affected by the changes in RcSPL1 expression.RcTAF15b protein,which is an autonomous pathway protein,was revealed to interact with RcSPL1.The silencing and overexpression of RcTAF15b in rose plants led to delayed and accelerated flowering,respectively.Collectively,the study findings imply that RcSPL1–RcTAF15b modulates the flowering time of rose plants. | Rui Yu Zhiying Xiong Xinhui Zhu Panpan Feng Ziyi Hu Rongxiang Fang Yuman Zhang Qinglin Liu | 2023 | Horticulture Research2023，10，6： | 0 |
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