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| 1 | RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。 | Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun | 2012 | Cell Research2012，22，5： | 66 |
| 2 | Precipitation and hot deformation behavior of austenitic heat-resistant steels: A review显示文摘The austenitic heat resistant-steels have been considered as important candidate materials for advanced supercritical boilers, nuclear reactors, super heaters and chemical reactors, due to their favorable combination of high strength, corrosion resistance, perfect mechanical properties, workability and low cost.Since the precipitation behavior of the steels during long-term service at elevated temperature would lead to the deterioration of mechanical properties, it is essential to clarify the evolution of secondary phases in the microstructure of the steels. Here, a summary of recent progress in the precipitation behavior and the coarsening mechanism of various precipitates during aging in austenitic steels is made. Various secondary phases are formed under service conditions, like MX carbonitrides, M_(23)C_6 carbides, Z phase, sigma phase and Laves phase. It is found that the coarsening rate of M_(23)C_6 carbides is much higher than that of MX carbonitrides. In order to understand the thermal deformation mechanism, a constitutive equation can be established, and thus obtained processing maps are beneficial to optimizing thermal processing parameters, leading to improved thermal processing properties of steels. | Yinghui Zhou Yongchang Liu Xiaosheng Zhou Chenxi Liu Jianxin Yu Yuan Huang Huijun Li Wenya Li | 2017 | Journal of Materials Science & Technology2017，33，12： | 12 |
| 3 | Queue Size Distribution of Geo/G/1 Queue Under the Min(N,D)-Policy显示文摘This paper considers a discrete-time Geo/G/1 queue under the Min(N,D)-policy in which the idle server resumes its service if either N customers accumulate in the system or the total backlog of the service times of the waiting customers exceeds D,whichever occurs first(Min(N,D)-policy).By using renewal process theory and total probability decomposition technique,the authors study the transient and equilibrium properties of the queue length from the beginning of the arbitrary initial state,and obtain both the recursive expression of the z-transformation of the transient queue length distribution and the recursive formula for calculating the steady state queue length at arbitrary time epoch n^+.Meanwhile,the authors obtain the explicit expressions of the additional queue length distribution.Furthermore,the important relations between the steady state queue length distributions at different time epochs n^-,n and n^+ are also reported.Finally,the authors give numerical examples to illustrate the effect of system parameters on the steady state queue length distribution,and also show from numerical results that the expressions of the steady state queue length distribution is important in the system capacity design. | GU Jianxiong WEI Yingyuan TANG Yinghui YU Miaomiao | 2016 | Journal of Systems Science & Complexity2016，29，3： | 12 |
| 4 | RELIABILITY INDICES OF DISCRETE-TIME Geo^X/G/1 QUEUEING SYSTEM WITH UNRELIABLE SERVICE STATION AND MULTIPLE ADAPTIVE DELAYED VACATIONS显示文摘这篇论文从可靠性研究的观点与不可靠的加油站和多重适应推迟的假期认为排队的分离时间的 GeoX/G/1 是模型。后面的问题将被讨论:1 ) 服务者在在时间 n 的一个概括忙时期的概率;2 ) 加油站在在时间 n 的失败的概率,即,加油站的短暂 unavailability,和加油站的稳定的州的 unavailability;3 ) 加油站失败的期望的数字在时间间隔期间(0, n ] ,并且加油站的稳定的州的失败频率;4 ) 加油站故障在的期望的数字一概括的服务者忙碌时期。最后,作者证明有不可靠的加油站的一些普通分离时间的排队模型是在这篇论文讨论的模型的特殊情况。 | Yinghui TANG Miaomiao YU Xi YUN Shujuan HUANG | 2012 | Journal of Systems Science & Complexity2012，25，6： | 8 |
| 5 | Geom/G_1,G_2/1/1 REPAIRABLE ERLANG LOSS SYSTEM WITH CATASTROPHE AND SECOND OPTIONAL SERVICE显示文摘这份报纸学习一个单身的服务器有 Bernoulli 到达过程和没有等待的空格的分离时间的厄兰损失系统。在系统的服务者被假定提供服务的二种不同类型,也就是必要、可选的服务,到顾客。在系统的操作期间,大祸的到达将毁坏系统并且同时劝诱顾客立即离开系统。用一种新类型分离增补可变技术,作者获得排队系统的一些性能特征包括不变的可获得性和系统的失败频率,为是闲散的服务器,的不变的可能性忙碌,故障和系统等等的损失概率。由数字例子,最后,作者在几项表演措施上学习系统参数的影响。 | Yinghui TANG Miaomiao YU Cailiang LI | 2011 | Journal of Systems Science & Complexity2011，24，3： | 6 |
| 6 | Development and utilization of a new chemically-induced soybean library with a high mutation density显示文摘Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl methanesulfonate(EMS)-induced soybean(Glycine max) population,consisting of 21,600 independent M_2 lines, was developed.Over 1,000 M_(4(5))families, with diverse abnormal phenotypes for seed composition, seed shape, plant morphology and maturity that are stably expressed across different environments and generations were identified. Phenotypic analysis of the population led to the identification of a yellow pigmentation mutant, gyl, that displayed significantly decreased chlorophyll(Chl) content and abnormal chloroplast development. Sequence analysis showed that gyl is allelic to Minn Gold, where a different single nucleotide polymorphism variation in the Mg-chelatase subunit gene(ChlI1a) results in golden yellow leaves. A cleaved amplified polymorphic sequence marker was developed and may be applied to marker-assisted selection for the golden yellow phenotype in soybean breeding. We show that the newly developed soybean EMS mutant population has potential for functional genomics research and genetic improvement in soybean. | Zhongfeng Li Lingxue Jiang Yansong Ma Zhongyan Wei Huilong Hong Zhangxiong Liu Jinhui Lei Ying Liu Rongxia Guan Yong Guo Longguo Jin Lijuan Zhang Yinghui Li Yulong Ren Wei He Ming Liu Nang Myint Phyu Sin Htwe Lin Liu Bingfu Guo Jian Song Bing Tan Guifeng Liu Maiquan Li Xianli Zhang Bo Liu Xuehui Shi Sining Han Sunan Hua Fulai Zhou Lili Yu Yanfei Li Shuang Wang Jun Wang Ruzhen Chang Lijuan Qiu | 2017 | Journal of Integrative Plant Biology2017，59，1： | 6 |
| 7 | Proteomic analysis of heat stress resistance of cucumber leaves when grafted onto Momordica rootstock显示文摘Various biotic and abiotic stresses threaten the cultivation of future agricultural crops.Among these stresses,heat stress is a major abiotic stress that substantially reduces agricultural productivity.Many strategies to enhance heat stress tolerance of crops have been developed,among which is grafting.Here,we show that Momordica-grafted cucumber scions have intrinsically enhanced chlorophyll content,leaf area,and net photosynthetic rate under heat stress compared to plants grafted onto cucumber rootstock.To investigate the mechanisms by which Momordica rootstock enhanced cucumber scions heat stress tolerance,comparative proteomic analysis of cucumber leaves in response to rootstock-grafting and/or heat stress was conducted.Seventy-seven differentially accumulated proteins involved in diverse biological processes were identified by two-dimensional electrophoresis(2-DE)in conjunction with matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry(MALDI-TOF/TOF MS).The following four main categories of proteins were involved:photosynthesis(42.8%),energy and metabolism(18.2%),defense response(14.3%),and protein and nucleic acid biosynthesis(11.7%).Proteomic analysis revealed that scions grafted onto Momordica rootstocks upregulated more proteins involved in photosynthesis compared to scions grafted onto cucumber rootstocks under heat stress and indicated enhanced photosynthetic capacity when seedlings were exposed to heat stress.Furthermore,the expression of photosynthesis-related genes in plants grafted onto Momordica rootstocks significantly increased in response to heat stress.In addition,increased high-temperature tolerance of plants grafted onto Momordica rootstock was associated with the accumulation of ribulose-1,5-bisphosphate carboxylase/oxygenase(Rubisco)and oxygen-evolving enhancer protein 1(OEE1).Taken together,the data indicated that Momordica rootstock might alleviate growth inhibition caused by heat stress by improving photosynthesis,providing valuable insight into enhancing heat stress tolerance in the global warming epoch. | Ye Xu Yinghui Yuan Nanshan Du Yu Wang Sheng Shu Jin Sun Shirong Guo | 2018 | Horticulture Research2018，5，1： | 6 |
| 8 | Mechanical properties and microstructure of TRIP steels produced using TSCR process显示文摘C-Si-Mn TRIP steels were produced using the thin slab casting and rolling (TSCR) process under simulation in laboratory. The results of tensile tests show that the yield strength,tensile strength,and the total elongation of the experimental TRIP steels are 430 MPa,610 MPa,and 28.4%,respectively. Optical microscopy,scanning electron microscopy (SEM),and transmission electron micros-copy (TEM) were employed to identify the microstructures of the TRIP steels. The final microstructures consist of ferrite,bainite,and retained austenite. The results of quantitative color metallography show that the fraction of the retained austenite is about 5.8%. | Yinghui Zhang Yanli Ma Yonglin Kang Hao Yu | 2006 | Journal of University of Science and Technology Beijing2006，13，5： | 4 |
| 9 | Expansion of the South China Sea basin:Constraints from magnetic anomaly stripes,sea floor topography,satellite gravity and submarine geothermics显示文摘The widely distributed E-W-trending magnetic anomaly stripes in the central basin and the N-Etrending magnetic anomaly stripes in the southwest sub-basin provide the most important evidence for Neogene expansion of the South China Sea.The expansion mechanism remains,however,controversial because of the lack of direct drilling data,non-systematic marine magnetic survey data,and irregular magnetic anomaly stripes with two obvious directions.For example,researchers have inferred different ages and episodes of expansion for the central basin and southwest sub-basin.Major controversy centers on the order of basinal expansion and the mechanism of expansion for the entire South China Sea basin.This study attempts to constrain these problems from a comprehensive analysis of the seafloor topography,magnetic anomaly stripes,regional aeromagnetic data,satellite gravity,and submarine geothermics.The mapped seafloor terrain shows that the central basin is a north-south rectangle that is relatively shallow with many seamounts,whereas the southwest sub-basin is wide in northeast,gradually narrows to the southwest,and is relatively deeper with fewer seamounts.Many magnetic anomaly stripes are present in the central basin with variable dimensions and directions that are dominantly EWtrending,followed by the NE-,NW- and NS-trending.Conversely such stripes are few in the southwest sub-basin and mainly NE-trending.Regional magnetic data suggest that the NW-trending Ailaoshan-Red River fault extends into the South China Sea,links with the central fault zone in the South China Sea,which extends further southward to Reed Tablemount.Satellite gravity data show that both the central basin and southwest sub-basin are composed of oceanic crust.The Changlong seamount is particularly visible in the southwest sub-basin and extends eastward to the Zhenbei seamount.Also a low gravity anomaly zone coincides with the central fault zone in the sub-basin.The submarine geothermic distribution demonstrates that the southwest sub-basin has a higher geothermal value than the central basin,and that the central fault zone is defined by a low thermal anomaly.This study suggests that NW-SE expansion of the southwest subbasin is later than the N-S expansion of the central basin with the sub-basin extending into the central basin and with both expansions ending at the same time.The expansion of southwestern sub-basin,similar to the Japanese Sea,is likely caused by left-lateral strike slip on the central fault zone in the South China Sea,which may have significance for finding oil and gas in this region. | Xuezhong Yu Chunji Xue Haigang Shi Weiping Zhu Yinghui Liu Hang Yin | 2017 | Geoscience Frontiers2017，8，1： | 3 |
| 10 | Modeling interplay between regional net ecosystem carbon balance and soil erosion for a crop-pasture region 显示文摘 | Gao Qiong Yu Mei Liu Yinghui | 2007 | Journal of Geohpysical Resarch-Biogeosciences2007，112，04： | 1 |
| 11 | An overview on oxyfuel coal combustion—State of the art research and technology development显示文摘 | Terry Wall Yinghui Liu Chris Spero Liza Elliott Sameer Khare Renu Rathnam Farida Zeenathal Behdad Moghtaderi Bart Buhre Changdong Sheng Raj Gupta Toshihiko Yamada Keiji Makino Jianglong Yu | 2009 | Chemical Engineering Research and Design2009，，8： | 1 |
| 12 | Thrombopoietin induced proliferation and differentiation of fetal liver CD34^+ cells with phenotype change from hemopoiesis to neurogenesis显示文摘BACKGROUND: Previous studies have reported a neurotrophin-like motif in the N-terminal receptor binding region of the thrombopoietin (TPO) molecule, and have described localization of TPO and TPO receptor in the brain. Therefore, it is believed that TPO may be involved in regulation of neurogenesis. OBJECTIVE: To validate the effect of TPO on trans-differentiation, or differentiation from hematopoietic stem cells (HSCs) to neural stem cells (NSCs). DESIGN, TIME AND SETTING: Comparative studies were performed from March 2004 to April 2007 at the Department of Experimental Medicine, Northern Hospital, and the Department of Immunology, Fourth Military Medical University of Chinese PLA. MATERIALS: Human fetal liver (FL) was obtained from fetuses after water-balloon abortion. Gestational age ranged from 16 to 20 weeks. The study was approved by the Institutional Review Board and Ethics Committee of the Northern Hospital. TPO was kindly provided by Genentech Inc (USA). Iscove's Modified Dulbecco's Medium (IMDM) and neurobasalTM medium were purchased from Invitrogen (USA). MACS CD34 multisort kit was purchased from Miltenyi Biotec (Germany). METHODS: CD34+ cells were isolated from human FL mononuclear cells using MACS CD34 multisort kit and cultured at 1 × 105/mL in IMDM, containing TPO for 60 days with weekly changes of half of the medium. After culturing for 30 and 60 days, the TPO-induced cells were resuspended in neurobasalTM medium containing 10% fetal brain extracts and plated in an 8-well BIOCOAT poly-D-Lysine Culture Slide and cul- tured for another 7 days. MAIN OUTCOME MEASURES: Cell number, viability, phenotype and expression of hemopoiesis-related and neurogenesis-related proteins were examined by trypan blue exclusion with hemocytometer, immunoblot, immunocytochemistry and flow cytometry. RESULTS: After 60 days of induction with TPO, the cell number increased by 4.6-fold compared to the ini- tial culture. Although the proportion of the cells expressing the hemopoietic stem cell associated antigen (CD34) decreased steadily, both proportions of the cultured FL-derived CD34+ cells expressing CD41a and CD61 remained unchanged, which still accounted for 10%. Noticeably, the proportions of the cells express- ing nestin and epidermal growth factor receptor increased significantly (both > 50%), whereas the expression of more mature neural or glial proteins [microtubule-associated protein-2 (MAP2), glial fibrillary acidic pro- tein (GFAP), oligodendrocyte marker O4 (O4)] markers on the cultured fetal liver derived-CD34+ cells were at lower levels. After another 7 days incubation in neurobasal? medium, these TPO-induced cells formed neurospheres, which were labeled with nestin, and differentiated into cells with morphological characteristics of neurons, astrocytes and oligodendrocytes, which were labeled with MAP-2, GFAP, and O4, respectively. CONCLUSION: TPO can induce FL-derived HSCs to differentiate or trans-differentiate into NSCs and its progenitors. | Ning Ma Dongchu Ma Yi Tao Yinghui Sun Di Lin Huiying Yu Jinlong Jian Wei Jia Boquan Jin | 2008 | Neural Regeneration Research2008，3，4： | 1 |
| 13 | Coherent coupling of vibrational states in the MEH-PPV film investigated through Multi-Color Photon Echo显示文摘The poly-[2-methoxy,(5-2′-ethyl-hexyloxy)-p-phenylene vinylene](MEH-PPV) film is investigated by means of the Multi-Color Photon Echo(MCPE) technique. Under the three-order nonlinear response theory,the reason for the occurrence of the quantum beats in the time domain and the relations among signal wavevector,pulse sequence and response function are discussed. The analysis of the Raman spectrum of MEH-PPV and the fast Fourier transformation(FFT) results of photon echo(PE) signal dynamics demonstrate the coherent coupling between the C==C bonds and the CC-H bonds and the coherent coupling between the C-C stretching of the phenyl group and the C==C stretching of the vinylene group. | YU GuoYang 1 ,SONG YunFei 1 ,WANG YingHui 1 ,LIU YuQiang 1 ,MO YueQi 2 & YANG YanQiang 1 1 Center for Condensed Matter Science and Technology,Department of Physics,Harbin Institute of Technology,Harbin 150001,China 2 College of Materials Science and Engineering,South China University of Technology,Guangzhou 510640,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，6： | 1 |
| 14 | A surface-fluorinated-TiO2-KMnO4 photocatalytic system for determination of chemical oxygen demand显示文摘 | ZHU Lihua CHEN Yu'e WU Yinghui | 2006 | Analytica Chimica Acta2006，571，： | 1 |
| 15 | Occurrence, Distribution and Sources of Organochlorine Pesticides (OCPs) in Surface Sediments from the Lijiang River, a Typical Karst River of Southwestern China显示文摘 | Dan Zhang Yinghui Wang Kefu Yu Pingyang Li Ruijie Zhang Yiyin Xu | 2014 | Bulletin of Environmental Contamination and Toxicology2014，，5： | 1 |
| 16 | Anaerobic biological treatment of high strength cassava starch wastewater in a new type up-flow multistage anaerobic reactor显示文摘 | Lei Sun Shungang Wan Zebin Yu Yinghui Wang Shuangfei Wang | 2011 | Bioresource Technology2011，，： | 1 |
| 17 | Development and genetic mapping of SSR markers in foxtail millet [Setaria italica (L.) P. Beauv.]显示文摘 | Xiaoping Jia Zhongbao Zhang Yinghui Liu Chengwei Zhang Yunsu Shi Yanchun Song Tianyu Wang Yu Li | 2009 | Theoretical and Applied Genetics2009，，4： | 1 |
| 18 | Application of an enzyme immunoassay for the quantitative determination of azo dye (Orange II) in food products显示文摘 | Huyin Xue Yue Xing Yongmei Yin Taichang Zhang Bo Zhang Yu Zhang Pei Song Xi Tian Yinghui Xu Peng Wang Meng Meng Rimo Xi | 2012 | Food Additives & Contaminants: Part A2012，，12： | 1 |
| 19 | Using of the surface plasmon resonance cytosensor for real-time and non-invasive monitoring of cellular effects in living C6 cells induced by PMA显示文摘Developing novel instruments and technologies for spatio-temporal and dynamic meas-urements of the intricate cellular effects involving molecular translocation, signal transduction, and molecular interactions inside living cells is essential for the cell and molecular biology science. For the purpose of monitoring and investigating molecular events in living cells at real-time, the surface plasmon resonance based cytosensor (SBCS) for cell cultur-ing and signal monitoring was established, and on the basis of it, the corresponding technology was also established by monitoring and analyzing SPR re-sponses induced in rat C6 glioma cells by phorbol 12-myristate 13-acetate (PMA). The SPR signals induced by PMA in living C6 cells were significantly different from those groups without cells. These re-sponses were strongly dependent on and saturable to the concentrations of PMA, and could be sup-pressed by the specific and potent PKC inhibitors, which indicated that the measured signal could be the reflection of the redistribution of intracellular components near the cell membrane triggered by the activation of PKC. This research provides a quantita-tive and non-invasive technique to study the spa-tio-temporal characteristics of the cellular effects in living cells at real-time. Furthermore, this technology could also be widely used in the basic research as well as applied realms, such as space effects evaluation, environmental safety assessment, bio-logical weapon detection, cellular and molecular re-search, and drug screening. | WANG Chunyan LI Yinghui XIONG Jianghui,TAN Yingjun YU Jianru | 2006 | Chinese Science Bulletin2006，51，8： | 1 |
| 20 | Artificial intelligence for the development and implementation guidelines for traditional Chinese medicine and integrated traditional Chinese and western medicine显示文摘The translation and implementation of clinical practice guidelines(CPGs)for Traditional Chinese Medicine(TCM)and Integrated Traditional Chinese and Western medicine is crucial to the adoption of medical science and technology,but the low operability and slow update of integrated traditional Chinese and Western Medicine guidelines,and the lack of integration between guidelines and clinical practice,result in the guidelines not having the desired clinical effects in practice.The application of Artificial Intelligence(AI)to the field of CPGs development aims to shorten the development time,optimize and accelerate the whole process of CPG’s development.This article summarized the current research and application status of AI in development and implementation CPGs for TCM and Integrated Traditional Chinese and Western medicine and proposed the method of Combining real world data and AI technology to enrich for TCM and Integrated Traditional Chinese and Western medicine. | Yinghui Jin Xiangying Ren Lina Yu Yongbo Wang Qiao Huang Xuhui Li Xiangge Ren Jiaao Lou Kuang Gao Mukun Chen Wenbin Hu Xiantao Zeng Hongcai Shang | 2021 | TMR Modern Herbal Medicine2021，4，2： | 1 |
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