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| 1 | Insights into the mechanism of CXCL12-mediated signaling in trophoblast functions and placental angiogenesis显示文摘chemokine CXCL12 和它的受体 CXCR4 是重要的表明为人的胚囊培植和怀孕的前进要求的部件。成长证据显示 CXCL12/CXCR4 轴能调整 trophoblast 功能和改变的子宫的螺线动脉,它在胎座式和胎儿的结果起一个基本作用。孤儿受体 CXCR7 也被相信部分调整 CXCL12/CXCR4 轴的功能。另外, CXCL12/CXCR4/CXCR7 轴能提高在象子宫的自然漂亮房间那样的 trophoblasts 和蜕膜的房间和涉及 trophoblast 区别和侵略和胎盘的 angiogenesis 的规定的蜕膜的 stromal 房间之间的串音。另外,最近的研究证明那 CXCL12 表情与 preeclampsia 在胎盘和怀孕女人的中间三个月的羊膜的液体被提高,暗示 CXCL12 的 dysregulation 起在 preeclampsia 的致病的一个作用。在 trophoblast 功能和胎盘的 angiogenesis 的调停 CXCL12 的发信号的规章的机制的进一步的理解可以帮助为联系怀孕的疾病设计新奇治疗学的途径。 | Liang Wang Xueyi Li Yilin Zhao Chao Fang Yingli Lian Wenli Gou Tao Han Xiaoming Zhu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，9： | 8 |
| 2 | Heterostructured graphene quantum dot/WSe2/Si photo-detector with suppressed dark current and improved detectivity显示文摘 | Mengxing Sun Qiyi Fang Dan Xie Yilin Sun Liu Qian Jianlong Xu Peng Xiao Changjiu Teng Weiwei Li Tianling Ren Yanfeng Zhang | 2018 | Nano Research2018，11，6： | 5 |
| 3 | 100 Hertz frame-rate switching threedimensional orbital angular momentum multiplexing holography via cross convolution显示文摘The orbital angular momentum(OAM)of light has been implemented as an information carrier in OAM holography.Holographic information can be multiplexed in theoretical unbounded OAM channels,promoting the applications of optically addressable dynamic display and high-security optical encryption.However,the frame-rate of the dynamic extraction of the information reconstruction process in OAM holography is physically determined by the switching speed of the incident OAM states,which is currently below 30 Hz limited by refreshing rate of the phase-modulation spatial light modulator(SLM).Here,based on a cross convolution with the spatial frequency of the OAM-multiplexing hologram,the spatial frequencies of an elaborately-designed amplitude distribution,namely amplitude decoding key,has been adopted for the extraction of three-dimensional holographic information encoded in a specific OAM information channel.We experimentally demonstrated a dynamic extraction frame rate of 100 Hz from an OAM multiplexing hologram with 10 information channels indicated by individual OAM values from-50 to 50.The new concept of cross convolution theorem can even provide the potential of parallel reproduction and distribution of information encoded in many OAM channels at various positions which boosts the capacity of information processing far beyond the traditional decoding methods.Thus,our results provide a holographic paradigm for high-speed 3D information processing,paving an unprecedented way to achieve the high-capacity short-range optical communication system. | Weijia Meng Yilin Hua Ke Cheng Baoli Li Tingting Liu Qinyu Chen Haitao Luan Min Gu Xinyuan Fang | 2022 | Opto-Electronic Science2022，1，9： | 2 |
| 4 | Multicomponent reactive transport modeling of uranium bioremediation field experiments 显示文摘 | Yilin Fang Steven B | 2009 | Geochimica et Cosmochimica Acta2009，73，： | 1 |
| 5 | Melatonin modulates the effects of diethylstilbestrol (DES) on the anterior pituitary of the female Wistar rat显示文摘 | Zhao Weijiang Shi Zhongfang Yuan Fang Li Guilin Sun Yilin Zhang Yazhuo Wang Zhongcheng | 2010 | Folia Histochemica et Cytobiologica2010，，2： | 1 |
| 6 | The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene显示文摘 | Yilin Xu Yang Yang Yanyan Cai Fang Liu Yingle Liu Ying Zhu Jianguo Wu | 2011 | Biochemical and Biophysical Research Communications2011，，3： | 1 |
| 7 | Image Generation of Tomato Leaf Disease Identification Based on Small-ACGAN显示文摘Plant diseases have become a challenging threat in the agricultural field.Various learning approaches for plant disease detection and classification have been adopted to detect and diagnose these diseases early.However,deep learning entails extensive data for training,and it may be challenging to collect plant datasets.Even though plant datasets can be collected,they may be uneven in quantity.As a result,the problem of classification model overfitting arises.This study targets this issue and proposes an auxiliary classifier GAN(small-ACGAN)model based on a small number of datasets to extend the available data.First,after comparing various attention mechanisms,this paper chose to add the lightweight Coordinate Attention(CA)to the generator module of Auxiliary Classifier GANs(ACGAN)to improve the image quality.Then,a gradient penalty mechanism was added to the loss function to improve the training stability of the model.Experiments show that the proposed method can best improve the recognition accuracy of the classifier with the doubled dataset.On AlexNet,the accuracy was increased by 11.2%.In addition,small-ACGAN outperformed the other three GANs used in the experiment.Moreover,the experimental accuracy,precision,recall,and F1 scores of the five convolutional neural network(CNN)classifiers on the enhanced dataset improved by an average of 3.74%,3.48%,3.74%,and 3.80%compared to the original dataset.Furthermore,the accuracy of MobileNetV3 reached 97.9%,which fully demonstrated the feasibility of this approach.The general experimental results indicate that the method proposed in this paper provides a new dataset expansion method for effectively improving the identification accuracy and can play an essential role in expanding the dataset of the sparse number of plant diseases. | Huaxin Zhou Ziying Fang Yilin Wang Mengjun Tong | 2023 | Computers, Materials & Continua2023，，7： | 1 |
| 8 | Genome-wide Analysis of a Plant AT-rich Sequence and Zinc-binding Protein (PLATZ) in Triticum Aestivum显示文摘Plant AT-rich sequence and zinc-binding protein(PLATZ)is a plant transcription factor that has been studied in corn.PLATZ can non-specifically bind to sequences rich in A/T bases to induce transcriptional repression.It is involved in the regulation of dehydration tolerance in seeds.In this study,we performed bioinformatics analysis to identify and characterize wheat PLATZ(TaPLATZ)genes.We identified 49 wheat PLATZ genes by searching the wheat genome by using known PLATZ gene sequences from rice,Arabidopsis,and maize.Phylogenetic analysis on PLATZ gene sequences from different species was performed.We found that PLATZs could be divided into three groups.The chromosome(chr)distribution analysis revealed that the 49 identified wheat PLATZ genes are distributed in 15 chrs.Gene structure and motif analyses indicated that most PLATZ genes possess conserved exon/intron arrangements and motif compositions.Our analysis of transcriptional data indicated that several wheat PLATZ genes may play an important role in abiotic stress resistance given that they are expressed under salt stress.The results of qRT-PCR further confirmed that TaPLATZ is involved in plant abiotic stress and is also related to the cell differentiation of plant tissues.Our results lay the foundation for further studies on the function of the wheat PLATZ gene family. | Xiaohang He Minjie Liu Zhengwu Fang Dongfang Ma Yilin Zhou Junliang Yin | 2021 | Phyton-International Journal of Experimental Botany2021，90，3： | 1 |
| 9 | Ionic liquids in transdermal drug delivery system: Current applications and future perspectives显示文摘The transdermal drug delivery(TDD) shows considerable advantages over other administration pathways.However, conventional enhancing permeation methods face a series of challenges owing to barrier function provided by the skin, of which enhancing abilities either are so strong that it results in toxicity and irritation, or too weak to achieve desirable therapeutical effects. To address these issues, it is an urgent need to develop a novel method to overcome the limitations of current measures. Fortunately, in the preceding decades, ionic liquids(ILs) have been extensively studied and increasingly applied in pharmaceutical drug delivery due to their unique physicochemical and biological properties. What is more, tunability of structure resolves the challenges in processing active pharmaceutical ingredient(API) formulation, such as polymorphism and poor solubility of drugs. Thus, the presence of ILs provides an ample design space for the transdermal drug delivery system(TDDS). This review discusses the shortcomings of conventional enhancing permeation methods and introduces the application of ILs in transdermal delivery from three aspects: i) ILs are applied as enhancers to weaken the barrier function of the stratum corneum(SC). ii) As counterions, ILs are combined with API to modify the physicochemical properties of drugs. iii) ILs assist in the design of transdermal preparation for perfecting formulation. This review comprehensively introduces the major breakthroughs made in the applications of ILs, which can serve as guidance to provide novel ideas for formulation scientists who hit the bottleneck in the development of TDD. | Yang Zhang Chao Liu Jiaqi Wang Shoujun Ren Yilin Song Peng Quan Liang Fang | 2023 | Chinese Chemical Letters2023，34，3： | 1 |
| 10 | Antibacterial mechanism of kojic acid and tea polyphenols against Escherichia coli O157:H7 through transcriptomic analysis显示文摘Escherichia coli O157:H7 is one of the major foodborne pathogenic bacterial that cause infectious diseases in humans.The previous found that a combination of kojic acid and tea polyphenols exhibited better activity against E.coli O157:H7 than using either alone.This study aimed to explore responses underlying the antibacterial mechanisms of kojic acid and tea polyphenols from the gene level.The functional enrichment analysis by comparing kojic acid and tea polyphenols individually or synergistically against E.coli O157:H7 found that acid resistance systems in kojic acid were activated,and the cell membrane and genomic DNA were destructed in the cells,resulting in“oxygen starvation”.The oxidative stress response triggered by tea polyphenols inhibited both sulfur uptake and the synthesis of ATP,which affected the bacteria's life metabolic process.Interestingly,we found that kojic acid combined with tea polyphenols hindered the uptake of iron that played an essential role in the synthesis of DNA,respiration,tricarboxylic acid cycle.The results suggested that the iron uptake pathways may represent a novel approach for kojic acid and tea polyphenols synergistically against E.coli O157:H7 and provided a theoretical basis for bacterial pathogen control in the food industry. | Yilin Lin Ruifei Wang Xiaoqing Li Keren Agyekumwaa Addo Meimei Fang Yehui Zhang Yigang Yu | 2024 | Food Science and Human Wellness2024，13，2： | 1 |
| 11 | Design, Synthesis, and Evaluation of 3-((4-(t-Butyl)-2-(2- benzylidenehydrazinyl)thiazol-5-yl)methyl)quinolin- 2(1H)-ones as Neuraminidase Inhibitors显示文摘一系列新奇的 3-((4-(t 丁基)-2-(2-benzylidenehydrazinyl)thiazol-5-yl)methyl)quinolin-2(1H)-ones (7a-7z ) 为他们禁止 neuraminidase (NA ) 的能力被设计,综合并且评估在里面 ? uenza H1N1 病毒。显示的一些混合物节制流行性感冒 NA 禁止的活动。有 2-(2-(2-methoxybenzylidene ) hydrazinyl ) 的支架的复合 7l thiazole 是最好的,有 44.66 µmol/L 的 IC 50 的展出中等 NA 禁止的活动。结构活动关系证明那在苯基戒指的帕拉位置在元位置和氯和溴组在 ortho 位置,氟的符号和 nitro 组与 methoxy 或 hydroxy 组加重是更活跃的。停靠学习显示复合 7l 与一些关键残余(包括的 Asp151, Glu119, Arg292, Tyr406,和 Asn347 ) 有重要相互作用并且绑在邻近 NA 活跃地点的 430 洞。 | Yilin Fang Mengwu Xiao Aixi Hu Jiao Ye Wenwen Lian Ailin Liu | 2016 | Chinese Journal of Chemistry2016，34，4： | 0 |
| 12 | Disruption of the autism-related gene Pak1 causes stereocilia disorganization,hair cell loss,and deafness in mice显示文摘Several clinical studies have reported that hearing loss is correlated with autism in children.However,little is known about the underlying mechanism between hearing loss and autism.p21-activated kinases(PAKs)are a family of serine/threonine kinases that can be activated by multiple signaling molecules,particularly the Rho family of small GTPases.Previous studies have shown that Pak1 mutations are associated with autism.In the present study,we take advantage of Pak1 knockout(Pak1a/a)mice to investigate the role of PAK1 in hearing function.We find that PAK1 is highly expressed in the postnatal mouse cochlea and that PAK1 deficiency leads to hair cell(HC)apoptosis and severe hearing loss.Further investigation indicates that PAK1 deficiency downregulates the phosphorylation of cofilin and ezrin-radixin-moesin and the expression of b II-spectrin,which further decreases the HC synapse density in the basal turn of cochlea and disorganized the HC stereocilia in all three turns of cochlea in Pak1à/àmice.Overall,our work demonstrates that the autism-related gene Pak1 plays a crucial role in hearing function.As the first candidate gene linking autism and hearing loss,Pak1 may serve as a potential target for the clinical diagnosis of autism-related hearing loss. | Cheng Cheng Yilin Hou Zhonghong Zhang Yanfei Wang Ling Lu Liyan Zhang Pei Jiang Song Gao Qiaojun Fang Chengwen Zhu Junyan Gao Xufeng Liu Wei Xie Zhengping Jia Zhigang Xu Xia Gao Renjie Chai | 2021 | Journal of Genetics and Genomics2021，48，4： | 0 |
| 13 | CEO Age, Earnings Management and Mergers & Acquisitions Evidence from China显示文摘This paper explores the relationship between CEO age in target firms, earnings management, mergers and acquisitions decision-making, and performance by using a sample of Chinese firms from 2008 to 2017. We found that CEO age is negatively correlated with M&A decision-making and target firms engage in a higher degree accrual-based earnings management(AEM) than non-target firms. In addition, target firms with young CEOs exhibit a greater extent of AEM in the pre-M&A period. We also found that the relationship between CEO age and M&A performance is inverted U-shaped. AEM of pre-M&A is negatively correlated with M&A performance, indicating that M&A performance is affected by AEM of pre-M&A. | Xinmiao FANG Jingxuan ZUO Yilin GAO Yan YU | 2022 | Journal of Systems Science and Information2022，10，6： | 0 |
| 14 | A preliminary site selection system for underground hydrogen storage in salt caverns and its application in Pingdingshan,China显示文摘Large‐scale underground hydrogen storage(UHS)provides a promising method for increasing the role of hydrogen in the process of carbon neutrality and energy transition.Of all the existing storage deposits,salt caverns are recognized as ideal sites for pure hydrogen storage.Evaluation and optimization of site selection for hydrogen storage facilities in salt caverns have become significant issues.In this article,the software CiteSpace is used to analyze and filter hot topics in published research.Based on a detailed classification and analysis,a“four‐factor”model for the site selection of salt cavern hydrogen storage is proposed,encompassing the dynamic demands of hydrogen energy,geological,hydrological,and ground factors of salt mines.Subsequently,20 basic indicators for comprehensive suitability grading of the target site were screened using the analytic hierarchy process and expert survey methods were adopted,which provided a preliminary site selection system for salt cavern hydrogen storage.Ultimately,the developed system was applied for the evaluation of salt cavern hydrogen storage sites in the salt mines of Pingdingshan City,Henan Province,thereby confirming its rationality and effectiveness.This research provides a feasible method and theoretical basis for the site selection of UHS in salt caverns in China. | Liangchao Huang Yanli Fang Zhengmeng Hou Yachen Xie Lin Wu Jiashun Luo Qichen Wang Yilin Guo Wei Sun | 2024 | Deep Underground Science and Engineering2024，3，1： | 0 |
| 15 | Current applications of artificial intelligence-based computer vision in laparoscopic surgery显示文摘Recent advances in artificial intelligence(AI)have sparked a surge in the application of computer vision(CV)in surgical video analysis.Laparoscopic surgery produces a large number of surgical videos,which provides a new opportunity for improving of CV technology in laparoscopic surgery.AI-based CV techniques may leverage these surgical video data to develop real-time automated decision support tools and surgeon training systems,which shows a new direction in dealing with the shortcomings of laparoscopic surgery.The effectiveness of CV applications in surgical procedures is still under early evaluation,so it is necessary to discuss challenges and obstacles.The review introduced the commonly used deep learning algorithms in CV and described their usage in detail in four application scenes,including phase recognition,anatomy detection,instrument detection and action recognition in laparoscopic surgery.The currently described applications of CV in laparoscopic surgery are limited.Most of the current research focuses on the identification of workflow and anatomical structure,while the identification of instruments and surgical actions is still awaiting further breakthroughs.Future research on the use of CV in laparoscopic surgery should focus on applications in more scenarios,such as surgeon skill assessment and the development of more efficient models. | Kangwei Guo Haisu Tao Yilin Zhu Baihong Li Chihua Fang Yinling Qian Jian Yang | 2023 | Laparoscopic, Endoscopic and Robotic Surgery2023，6，3： | 0 |
| 16 | Optical colorimetric LiTaO_(3)wafers for highprecision lithography on frequency control of SAW devices显示文摘Surface acoustic wave(SAW)resonators based on lithium tantalate(LT,LiTaO_(3))wafers are crucial elements of mobile communication filters.The use of intrinsic LT wafers typically brings about low fabrication accuracy of SAW resonators due to strong UV reflection in the lithography process.This hinders their resonance frequency control seriously in industrial manufacture.LT doping and chemical reduction could be applied to decrease the UV reflection of LT wafers for high lithographic precision.However,conventional methods fail to provide a fast and nondestructive approach to identify the UV performance of standard single-side polished LT wafers for highprecision frequency control.Here,we propose a convenient on-line sensing scheme based on the colorimetry of reduced Fe-doped LT wafers and build up an automatic testing system for industrial applications.The levels of Fe doping and chemical reduction are evaluated by the lightness and color difference of LT-based wafers.The correlation between the wafer visible colorimetry and UV reflection is established to refine the lithography process and specifically manipulate the frequency performance of SAW resonators.Our study provides a powerful tool for the fabrication control of SAW resonators and will inspire more applications on sophisticated devices of mobile communication. | MING HUI FANG YINONG XIE FANGQI XUE ZHILIN WU JUN SHI SHENG YU YANG YILIN LIU ZHIHUANG LIU HSIN CHI WANG FAJUN LI QING HUO LIU JINFENG ZHU | 2024 | Photonics Research2024，12，2： | 0 |
| 17 | Acoustic Characteristics of Advertisement Calls in Babina adenopleura显示文摘Acoustic communication is the most important form of communication in anuran amphibians. To understand the acoustic characteristics of male Babina adenopleura, we recorded advertisement calls and analyzed their acoustic parameters during the breeding season. Male B. adenopleura produced calls with a variable number of notes(1–5), and each note contained harmonics. Although 6% of call notes did not exhibit frequency modulation(FM), two call note FM patterns were observed:(1) upward FM;(2) upward–downward FM. With the exception of 1- and 5- note calls, the duration of successive notes decreased monotonically. With the exception of 1 note calls, the fundamental frequency of the first note was lowest, then increased; the greatest change in the fundamental frequency was always between notes 1 and 2. The dominant frequency varied between calls. For example for the first call note the dominant frequency occurred in some cases in the first harmonic(located in the 605.320 ± 64.533 Hz frequency band), the second harmonic(918 ± 9 Hz band), the fourth harmonic(1712 ± 333 Hz band), the sixth harmonic(the 2165 ± 152 Hz band), the seventh harmonic(the 2269 ± 140 Hz band), the eighth harmonic(the 2466 ± 15 Hz band) or the ninth harmonic(the 2636 ± 21 Hz band). Although male B. adenopleura advertisement calls have a distinctive structure, they have similar characteristics to the calls of the music frog, B. daunchina. | Xiaobin FANG Xia QIU Yilin ZHOU Luyi YANG Yi ZHAO Weihong ZHENG Jinsong LIU | 2015 | Asian Herpetological Research2015，6，3： | 0 |
| 18 | Phyllotaxis bionics for vortex nanosieves显示文摘eLight,1(5),2021 http://gffzzd3cc09b8251d45dfsf0fqq6nconn560qu.ffgz.tsg.suse.edu.cn/10.1186/s43593-021-00005-9 Simultaneous generation of multiple optical vortex(OV)lies at the heart of the application for orbital angular momentum(OAM)multiplexing both in classical and quantum domains.Previous structure with segmented or interleaved functional sub-areas in a single nano-device has been developed at the cost of its compactness and channel capacity.Back-to-nature design inspired by the spiral phyllotaxis pattern in this work offers a fresh way to fabricate a truly space-degenerated nanoscale multipleOVs-generator,namely vortex nanosieves. | Min Gu Yilin Hua and Xinyuan Fang | 2021 | Light(Science & Applications)2021，10，10： | 0 |
| 19 | Impact of Ta/Ti electrodes on linearities of TaOx-based resistive random-access memories for neuromorphic computing显示文摘In this work,by incorporating different electrodes(Ta/Ti)onto TaOxdielectric layer,we studied both the conductance reading and conductance updating(long term potentiation and depression)linearities in the two RRAM devices.Owing to the composition modulation(CM)mechanism,the Ta-electrode device shows better conductance reading and updating linearities.The RRAM device linearities directly influence the performance of the neural network when the devices are used as synapses.System evaluation of a two-layer neural network considering the conductance reading and updating linearity factors further confirm that both the training and inference accuracies of Ta electrode device are better than those of the Ti electrode one.We believe that this work could serve as a powerful reference for engineering synaptic devices with good linearity for neuromorphic computing applications. | YiLin Fang Tuo Shi XuMeng Zhang ZuHeng Wu JunJie An JinSong Wei Jian Lu Qi Liu | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，9： | 0 |
| 20 | Decade Milestone Advancement of Defect-Engineered g-C_(3)N_(4) for Solar Catalytic Applications显示文摘Over the past decade, graphitic carbon nitride(g-C_(3)N_(4)) has emerged as a universal photocatalyst toward various sustainable carbo-neutral technologies. Despite solar applications discrepancy, g-C_(3)N_(4) is still confronted with a general fatal issue of insufficient supply of thermodynamically active photocarriers due to its inferior solar harvesting ability and sluggish charge transfer dynamics. Fortunately, this could be significantly alleviated by the “all-in-one” defect engineering strategy, which enables a simultaneous amelioration of both textural uniqueness and intrinsic electronic band structures. To this end, we have summarized an unprecedently comprehensive discussion on defect controls including the vacancy/non-metallic dopant creation with optimized electronic band structure and electronic density, metallic doping with ultraactive coordinated environment(M–N_(x), M–C_(2)N_(2), M–O bonding), functional group grafting with optimized band structure, and promoted crystallinity with extended conjugation π system with weakened interlayered van der Waals interaction. Among them, the defect states induced by various defect types such as N vacancy, P/S/halogen dopants, and cyano group in boosting solar harvesting and accelerating photocarrier transfer have also been emphasized. More importantly, the shallow defect traps identified by femtosecond transient absorption spectra(fs-TAS) have also been highlighted. It is believed that this review would pave the way for future readers with a unique insight into a more precise defective g-C_(3)N_(4) “customization”, motivating more profound thinking and flourishing research outputs on g-C_(3)N_(4)-based photocatalysis. | Shaoqi Hou Xiaochun Gao Xingyue Lv Yilin Zhao Xitao Yin Ying Liu Juan Fang Xingxing Yu Xiaoguang Ma Tianyi Ma Dawei Su | 2024 | Nano-Micro Letters2024，16，4： | 0 |
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