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| 1 | Association between coexisting intracranial artery and extracranial carotid artery atherosclerotic diseases and ipsilateral cerebral infarction: a Chinese Atherosclerosis Risk Evaluation (CARE- II) study显示文摘Background To evaluate the association between coexisting intracranial and extracranial carotid artery atherosclerotic diseases and ipsilateral acute cerebral infarct(ACI)in symptomatic patients by using magnetic resonance(MR)vessel wall imaging.Methods Symptomatic patients were recruited from a cross-sectional,multicentre study of Chinese Atherosclerosis Risk Evaluation(CARE-II).All patients underwent MR imaging for extracranial carotid arterial wall,intracranial artery and brain.Coexisting intracranial stenosis≥50%and extracranial carotid artery mean wall thickness(MWT)≥1 mm and plaque compositions at the same side were evaluated and the ipsilateral ACI was identified.The association between coexisting atherosclerotic diseases and ACI was evaluated using logistic regression.Results 351 patients were recruited.Patients with ipsilateral ACI had significantly greater prevalence of coexisting intracranial stenosis≥50%and carotid MWT≥1 mm(20.5%vs 4.9%,p<0.001),calcification(15.1%vs 4.4%,p=0.001)and lipid-rich necrotic core(LRNC)(19.2%vs 7.8%,p=0.002)compared with those without.Coexisting intracranial artery stenosis≥50%and carotid MWT≥1 mm(OR 5.043,95%CI 2.378 to 10.694;p<0.001),calcification(OR 3.864,95%CI 1.723 to 8.664;p=0.001)and LRNC(OR 2.803,95%CI 1.455 to 5.401;p=0.002)were significantly associated with ipsilateral ACI.After adjusting for confounding factors,the aforementioned associations remained statistically significant(intracranial stenosis≥50%coexisting with carotid MWT≥1 mm:OR 4.313,95%CI 1.937 to 9.601,p<0.001;calcification:OR 3.606,95%CI 1.513 to 8.593,p=0.004;LRNC:OR 2.358,95%CI 1.166 to 4.769,p=0.017).Conclusions Coexistence of intracranial artery severe stenosis and extracranial carotid artery large burden and intraplaque components of calcification and LRNC are independently associated with ipsilateral ACI.Trial registration number http://gffzz1caf53c915c04334sokook0oobwuw6wwc.ffgz.tsg.suse.edu.cn/.Unique identifier:NCT02017756. | Chunxiu Jiang Jing Zhang Jianbin Zhu Xianlong Wang Zhibo Wen Xihai Zhao Chun Yuan On behalf of CARE-II Investigators | 2021 | Stroke & Vascular Neurology2021，6，4： | 11 |
| 2 | A 2-bp insertion(c.6768insCC) in MC1R causes recessive white coat color in Bama miniature pigs显示文摘Coat color is an important characteristic of various breeds of domestic animal species.Variation in farm animal coat color is of considerable interest for concealment,communication and protection against solar radiation(Slominski et al.,2004).It also plays an important role in the regulation of physiological processes(Miyagi and Terai,2013).Bama miniature pigs are a native breed | Qitao Jia Chunwei Cao Hai Tang Ying Zhang Qiantao Zheng Xiao Wang Rui Zhang Xianlong Wang Ailing Luo Hong Wei Anming Meng Qi Zhou Hongmei Wang Jianguo Zhao | 2017 | Journal of Genetics and Genomics2017，44，4： | 5 |
| 3 | Hepatic encephalopathy complicated with hyponatremia and acid-base disturbance and its prognosis显示文摘Objective:To improve the diagnosis and therapeutic effect of occurrence and development of hyponatremia and disorder of acid-base balance among patients with hepatic encephalopathy(HE) by elucidating the regularity and mechanism,as well as its influence on prognosis.Methods:327 HE patients admitted to our hospital from January 1990 to June 2010 were enrolled.Meanwhile 316 patients hospitalized in the medical department of the same hospital were chosen as the control group.Patients in both groups were given the same methods to measure arterial blood gas parameters(pH value,PaCO2,[HCO3-],TCO2,BE and SaO2),blood biochemistry([Na+],[K+],[Cl-]),liver function,kidney function and blood glucose,serum sodium,and thereupon tocalculate the anion gap(AG) and the potential [HCO3-],and acid-base balance disorder.Results:Among the 327 HE patients,hyponatremia was found in 188 cases(57.4%),of whom 132 patients died(70.2%).While among the 316 patients in control group,68 presented with hyponatremia(21.5%),and 19 died(27.9%).The incidence and mortality were significantly different between the two groups(P<0.001).All the 327 patients presented with different degrees of acid-base balance disorder and 178 died(54.4%),in whom 164(50.2%) belonged to simple acid-base balance disorder and 74(45.1%) died,136(41.6%) were dual acid-base balance disorder and 80(58.8%) died,27(8.2%) were triple acid-base disturbance and 24(88.9%) died.Whereas in the control group only 83 patients(26.2%) were recognized as simple and dual acid-base balance disorder,and 18(21.7%) died.There was higher incidence of acid-base balance disorder and mortality rate in HE group than control one(P<0.001).Conclusion:Hyponatremia is valuable to judge HE patients' prognosis.The key parameters in the judgment and evaluation on acid-base balance disorder among HE patients are the change of pH values and serum electrolyte values.When pH value ≤ 7.30 or > 7.55,it generally suggests a poor prognosis. | Ren Chengshan Wang Lei Zhao Xiaoyan Yang Shiming Zhang Yanqi Wang Xiwen Bo Jianying Zhang Pengbin Guo Hong Ling Xianlong Li Yihui Da Siping Xie Xia Ren Wei Li Chunhua Qian Guisheng | 2012 | Journal of Medical Colleges of PLA(China)2012，27，3： | 3 |
| 4 | PM_(2.5)and water-soluble inorganic ion concentrations decreased faster in urban than rural areas in China显示文摘We investigated variations of PM_(2.5)and water-soluble inorganic ions chemical characteristics at nine urban and rural sites in China using ground-based observations.From 2015 to 2019,mean PM_(2.5)concentration across all sites decreased by 41.9μg/m~3with a decline of 46%at urban sites and 28%at rural sites,where secondary inorganic aerosol(SIAs)contributed to 21%(urban sites)and 17%(rural sites)of the decreased PM_(2.5).SIAs concentrations underwent a decline at urban locations,while sulfate(SO_(4)^(2–)),nitrate(NO_(3)^(–)),and ammonium(NH_(4)^(+))decreased by 49.5%,31.3%and 31.6%,respectively.However,only SO_(4)^(2–)decreased at rural sites,NO_(3)^(–)increased by 21%and NH_(4)^(+)decreased slightly.Those changes contributed to an overall SIAs increase in 2019.Higher molar ratios of NO_(3)^(–)to SO_(4)^(2–)and NH_(4)^(+)to SO_(4)^(2–)were observed at urban sites than rural sites,being highest in the heavily polluted days.Mean molar ratios of NH_(3)/NH_xwere higher in 2019 than 2015 at both urban and rural sites,implying increasing NH_xremained as free NH_(3).Our observations indicated a slower transition from sulfate-driven to nitrate-driven aerosol pollution and less efficient control of NO_(x)than SO_(2)related aerosol formation in rural regions than urban regions.Moreover,the common factor at urban and rural sites appears to be a combination of lower SO_(4)^(2–)levels and an increasing fraction of NO_(3)^(–)to PM_(2.5)under NH_(4)^(+)-rich conditions.Our findings imply that synchronous reduction in NO_(x)and NH_(3)emissions especially rural areas would be effective to mitigate NO_(3)^(–)-driven aerosol pollution. | Yangyang Zhang Aohan Tang Chen Wang Xin Ma Yunzhe Li Wen Xu Xiaoping Xia Aihua Zheng Wenqing Li Zengguo Fang Xiufen Zhao Xianlong Peng Yuping Zhang Jian Han Lijuan Zhang Jeffrey L.Collett Jr Xuejun Liu | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 5 | Salt-assisted growth and ultrafast photocarrier dynamics of large-sized monolayer ReSe2显示文摘Owing to its anisotropic optical and electrical properties,rhenium diselenide(ReSe2)has garnered considerable attention recently as a candidate material for polarization-sensitive photodetectors.However,the direct and controllable synthesis of large-sized ReSe2 with a uniform thickness is still a great challenge.Herein,we have refined the synthesis method to obtain uniform monolayer ReSe2 flakes with a size of up to^106μm on sapphire via an ambient-pressure chemical vapor deposition technique using Na promoter from sodium chloride.Interestingly,optical pump-probe spectroscopy revealed a fast switching from saturable absorption(SA)to absorption enhancement(AE)in subpicosecond time scale,followed by a slower decay induced by exciton recombination.Furthermore,both AE and SA signals exhibited clear angular dependence with a periodicity of 180°,which reflected the dichroism in nonlinear absorption dynamics.In addition,the photocarrier dynamics including free-carrier transport and subpicosecond relaxation due to exciton formation or surface trapping was probed using time resolved terahertz spectroscopy.We believe that our study serves as a reference for atomically controlled synthesis of large-sized ReSe2 and provides useful insights on its optoelectronic properties for novel device applications. | Shaolong Jiang Jin Yang Yuping Shi Jing Zhao Chunyu Xie Liyun Zhao Jiatian Fu Pengfei Yang Yahuan Huan Qin Xie Huachao Jiang Qing Zhang Xianlong Wang Fuhai Su Yanfeng Zhang | 2020 | Nano Research2020，13，3： | 2 |
| 6 | Review on partially coherent vortex beams显示文摘Ever since vortex beams were proposed, they are known for owning phase singularity and carrying orbital angular momentum (OAM). In the past decades, coherent optics developed rapidly. Vortex beams have been extended from fully coherent light to partially coherent light, from scalar light to vector light, from integral topological charge (TC) to fractional TC. Partially coherent vortex beams have attracted tremendous interest due to their hidden correlation singularity and unique propagation properties (e.g., beam shaping, beam rotation and self-reconstruction). Based on the sufficient condition for devising a genuine correlation function of partially coherent beam, partially coherent vortex beams with nonconventional correlation functions (i.e., non-Gaussian correlated Schell-model functions) were introduced recently. This timely review summarizes basic concepts, theoretical models, generation and propagation of partially coherent vortex beams. | Jun ZENG Rong LIN Xianlong LIU Chengliang ZHAO Yangjian CAI | 2019 | Frontiers of Optoelectronics2019，12，3： | 1 |
| 7 | Endoscopic Resection of Small Gastrointestinal Stromal Tumors显示文摘 | Jianying Bai Yiqin Wang Hong Guo Pengbin Zhang Xianlong Ling Xiaoyan Zhao | 2010 | Digestive Diseases and Sciences2010，，7： | 1 |
| 8 | Design of Y422 Retrievable Fracture Bridge Plug and Analysis of Slip Characteristics 显示文摘 | Li Dianxin Zhao Honglin Liu Xianlong | 2010 | Advanced Materials Research2010，，： | 1 |
| 9 | Endoscopic Resection of Small Gastrointestinal Stromal Tumors显示文摘 | Jianying Bai Yiqin Wang Hong Guo Pengbin Zhang Xianlong Ling Xiaoyan Zhao | 2010 | Digestive Diseases and Sciences2010，，7： | 1 |
| 10 | Urinary metabonomics study on the protective effects of ergosta-4,6, 8 ( 14 ),22-tetraen-3-one on chronic renal failure in rats using UPLC Q-TOF/MS and a novel MS-E data collection technique显示文摘 | Yingyong Zhao Xuefeng Shen Xianlong Cheng | 2012 | Process biochemistry2012，47，12： | 1 |
| 11 | Improvement of voltage stability of transmission system with parallel compensation显示文摘 | ZHAO Yongchao ZHAO Xianlong | 2013 | Journal of Shenyang University2013，25，1： | 1 |
| 12 | Synergistic effects of dual Zn/Ag ion implantation in osteogenic activity and antibacterial ability of titanium显示文摘 | Guodong Jin Hui Qin Huiliang Cao Shi Qian Yaochao Zhao Xiaochun Peng Xianlong Zhang Xuanyong Liu Paul K. Chu | 2014 | Biomaterials2014，，： | 1 |
| 13 | Characterization of CoMn catalyst by in situ X-ray absorption spectroscopy and wavelet analysis for Fischer–Tropsch to olefins reaction显示文摘Cobalt carbide has recently been reported to catalyse the FTO con version of syngas with high selectivity for the production of lower olefins (C2-C4). Clarifying the formation process and atomic structure of cobalt carbide will help understand the catalytic mechanism of FTO. Herein, hydrogenati on of carb on monoxide was investigated for cobalt carbide synthesized from CoMn catalyst, followed by X-ray diffraction, transmission electron microscopy, temperature programmed reaction and in situ X-ray absorption spectroscopy. By monitoring the evolution of cobalt carbide during syngas conversion, the wavelet transform results give evidenee for the formation of the cobalt carbide and clearly demonstrate that the active site of catalysis was cobalt carbide. | Ruoou Yang Zhaoming Xia Ziang Zhao Fanfei Sun Xianlong Du Haisheng Yu Songqi Gu Liangshu Zhong Jingtai Zhao Yunjie Ding Zheng Jiang | 2019 | Journal of Energy Chemistry2019，28，5： | 0 |
| 14 | Antitumor drug-induced acute pancreatitis:report of a special case显示文摘导致药的尖锐胰腺炎(弹跳) 当有相应临床的表明的胰腺炎源于导致药的胰腺的分泌物机能障碍和胰腺的织物损坏,被定义。一个案例弹跳源于 chemotherapeutics (Nimustine ) 被诊断并且对待我们的在里面在 2009 的医院。这个病人属于 anticancer 药导致的胰腺炎,并且 anticancer 药的毒性对胰腺的房间直接起作用,导致胰腺炎的出现。在治疗以后,胰腺炎有效地在病人和他的家庭最后放弃了的这个病人,而是期末考试被对待治疗由于加重的主要疾病。 | Wang Xingwei Zhou Gang Zhao Xiaoyan Guo Hong Wang Lei Ling Xianlong Deng Lei Yang Xin | 2010 | Journal of Medical Colleges of PLA(China)2010，25，6： | 0 |
| 15 | Traffic-load prediction based on echo state network improved by Bayesian theory in 10G-EPON显示文摘With the evolution of 10-gigabit Ethernet passive optical network(10G-EPON), the traffic-load prediction ability is necessary to support soaring services traffic with diversified characteristics and requirements. As a strong candidate to be used for the traffic-load prediction, the echo state network(ESN) may face the pseudo-regression problem and need to be improved for the better traffic-load prediction. To overcome this problem, this paper proposes an ESN based traffic-load prediction scheme using Bayesian theory in 10G-EPON for future-proof. In this proposed approach, Bayesian probability is introduced into the ESN and is used to improve the performance of ESN. According to the architecture between optical line terminal(OLT) and optical network units(ONU) in 10G-EPON, an ESN based on the Bayesian theory(B-ESN) is realized and the B-ESN based traffic load prediction scheme is also developed in OLT. Experiment results show that the proposed scheme can greatly better the accuracy of traffic-load prediction with lower complex degree. | Bai Huifeng Zhao Xianlong Zhou Hongfeng Zhang Likun | 2015 | The Journal of China Universities of Posts and Telecommunications2015，22，2： | 0 |
| 16 | Peutz-Jeghers syndrome: a report of 5 cases显示文摘Peutz-Jeghers syndrome (PJS), also known as hereditary intestinal polyposis syndrome, is an autosomal dominant genetic disease characterized by the development of benign hamartomatous polyps in the gastrointestinal tract and hyperpigmented macules on the lips and oral mucosa. Here, we reported 5 cases of PJS and our experience about its diagnosis and treatment. | Wang Xingwei Fan Chaoqiang Que Dan Guo Hong Wang Lei Ling Xianlong Deng Lei Zhao Xiaoyan | 2011 | Journal of Medical Colleges of PLA(China)2011，26，4： | 0 |
| 17 | Cytochrome P450 mono-oxygenase CYP703A2 plays a central role in sporopollenin formation and ms5ms6 fertility in cotton显示文摘The double-recessive genic male-sterile(ms)line ms5 ms6 has been used to develop cotton(Gossypium hirsutum)hybrids for many years,but its molecular-genetic basis has remained unclear.Here,we identified the Ms5 and Ms6 loci through map-based cloning and confirmed their function in male sterility through CRISPR/Cas9 gene editing.Ms5 and Ms6 are highly expressed in stages 7–9 anthers and encode the cytochrome P450 mono-oxygenases CYP703A2-A and CYP703A2-D.The ms5 mutant carries a single-nucleotide C-to-T nonsense mutation leading to premature chain termination at amino acid 312(GhCYP703A2-A^(312aa)),and ms6 carries three nonsynonymous substitutions(D98E,E168K,and G198R)and a synonymous mutation(L11L).Enzyme assays showed that GhCYP703A2 proteins hydroxylate fatty acids,and the ms5(GhCYP703A2-A^(312aa))and ms6(GhCYP703A2-D^(D98E,E168K,G198R))mutant proteins have decreased enzyme activities.Biochemical and lipidomic analyses showed that in ms5 ms6 plants,C12–C18 free fatty acid and phospholipid levels are significantly elevated in stages 7–9 anthers,while stages 8–10 anthers lack sporopollenin fluorescence around the pollen,causing microspore degradation and male sterility.Overall,our characterization uncovered functions of GhCYP703A2 in sporopollenin formation and fertility,providing guidance for creating male-sterile lines to facilitate hybrid cotton production and therefore exploit heterosis for improvement of cotton. | Huanhuan Ma Yuanlong Wu Ruiling Lv Huabin Chi Yunlong Zhao Yanlong Li Hongbo Liu Yizan Ma Longfu Zhu Xiaoping Guo Jie Kong Jianyong Wu Chaozhu Xing Xianlong Zhang Ling Min | 2022 | Journal of Integrative Plant Biology2022，64，10： | 0 |
| 18 | A 16-bit,±10-V Input Range SAR ADC with a 5-V Supply Voltage and Mixed-Signal Nonlinearity Calibration显示文摘This paper presents a high-precision,successive approximation register(SAR)analog-to-digital converter(ADC)with resistive analog front-end for lowvoltage and wide input range applications.To suppress the serious nonlinearity brought by the voltage coefficients of analog front-end without deteriorating differential nonlinearity performance,a mixed-signal calibration scheme based on piecewise-linear method with calibration digital-to-analog converter is proposed.A compensation current is designed to sink or source from the reference to keep it independent of input signal,which greatly improves the linearity performance.Fabricated in a 0.5-μm CMOS process,the proposed ADC achieves 88-dB signalto-noise-and-distortion ratio and 103-dB spurious free dynamic range with 5-V supply voltage and 2.5-V reference voltage,and the total power consumption is 37.5 mW. | LUO Hongrui ZHAO Xianlong JIAO Zihao ZHANG Jie WANG Xiaofei ZHANG Ruizhi ZHANG Hong | 2022 | Chinese Journal of Electronics2022，31，4： | 0 |
| 19 | Clinical features of 162 fatal cases of COVID-19:a multi-center retrospective study显示文摘Background:The coronavirus disease 2019(COVID-19)has affected approximately 2 million individuals worldwide;however,data regarding fatal cases have been limited.Objective:To report the clinical features of 162 fatal cases of COVID-19 from 5 hospitals in Wuhan between December 30,2019 and March 12,2020.Methods:The demographic data,signs and symptoms,clinical course,comorbidities,laboratory findings,computed tomographic(CT)scans,treatments,and complications of the patients with fatal cases were retrieved from electronic medical records.Results:The median patient age was 69.5(interquartile range:63.0–77.25)years,and 80%of the patients were over 61 years.A total of 112(69.1%)patients were men.Hypertension(45.1%)was the most common comorbidity,while 59(36.4%)patients had no comorbidity.At admission,131(81.9%)patients had severe or critical COVID-19,whereas 39(18.1%)patients with hypertension or chronic lung disease had moderate COVID-19.In total,126(77.8%)patients received antiviral treatment,while 132(81.5%)patients received glucocorticoid treatment.A total of 116(71.6%)patients were admitted to the intensive care unit(ICU),and 137(85.1%)patients received mechanical ventilation.Most patients received mechanical ventilation before ICU admission.Approximately 93.2%of the patients developed respiratory failure or acute respiratory distress syndrome.There were no significant differences in the inhospital survival time among the hospitals(P=0.14).Conclusion:Young patients with moderate COVID-19 without comorbidity at admission could also develop fatal outcomes.The in-hospital survival time of the fatal cases was similar among the hospitals of different levels in Wuhan. | Xianlong Zhou Guoyong Ding Qing Fang Jun Guo Luyu Yang Ping Wang Shou-Zhi Fu Ang Li Jian Xia Jiangtao Yu Jianyou Xia Min Ma Zhuanzhuan Hu Lei Huang Ruining Liu Cheng Jiang Shaoping Li Mingxia Yu Xizhu Xu Yan Zhao Quan Hu Weijia Xing Zhigang Zhao | 2022 | Emergency and Critical Care Medicine2022，2，3： | 0 |
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