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| 1 | Timing of the Wudangshan, Yaolinghe volcanic sequences and mafic sills in South Qinling: U-Pb zircon geochronology and tectonic implication显示文摘The Wudangshan, Yaolinghe volcanic-sedimentary sequences and doleritic-gabbroic sills comprise the largest exposed Precambrian basement in South Qinling. Zircons separated from 5 volcanic-pyroclas- tic samples of the Wudangshan Group, 2 volcanic samples of the Yaolinghe Group and one sample for the mafic sills were used for U-Pb dating by laser ablation-inductively coupled plasma mass spec- trometry (LA-ICPMS). The results reveal that the Wudangshan volcanic sequence was formed at (755±3) Ma (a weighted mean from the 5 samples, MSWD=0.47), whereas the Yaolinghe volcanic suite and the mafic sill were crystallized at (685±5) (2 samples, MSWD=0.36) and (679±3) Ma (MSWD=1.6), respectively, which are equal to each other within analysis errors. These ages are markedly younger than those previously documented for the rocks. The newly obtained ages for the Wudangshan and Yaolinghe Groups are identical to those of the bottom Liantuo and slightly older than those of the Nantuo Forma- tions, respectively, lower strata of the Nanhua (middle to late Neoproterozoic) stratotype section in eastern Three Gorges, Yangtze craton. A range of inherited magmatic zircons was recognized with ages of 830 to 780 Ma, which are typical of Neoprotzrozoic magmatisms recorded along the margins and interior of the Yangtze craton. Thus, there is Neoproterozoic basement comprising 830―780 Ma igne- ous suites in South Qinling; the inherited zircons were detrital sediments derived from the northern margin of the Yangtze craton. Accordingly, it is suggested that the South Qinling is a segment of the Yangtze craton before the Qinling Orogeny. | LING WenLi REN BangFang DUAN RuiChun LIU XiaoMing MAO XinWu PENG LianHong LIU ZaoXue CHENG JianPing YANG HongMei | 2008 | Chinese Science Bulletin2008，53，14： | 44 |
| 2 | U-Pb dating of detrital zircons from the Wudangshan Group in the South Qinling and its geological significance显示文摘U-Pb dating was made by the LA-ICP-MS method for detrital zircons from the Wudangshan volcanic-sedimentary succession in the South Qinling. Samples comprise quartz sandstones of the Wudangshan Group collected from the base of the Yangping For-mation and an upper layer of the Shuangtai Formation overlain its volcanic sequence, and two river-sand collections from the drainage systems cutting across the two formations, respectively. The results show that the Yangping detrital zircons are domi-nated by 830–780 Ma grains with a minor population of ~1.0–0.84 Ga and sporadic grains of ~2.6, ~2.4 and 2.0 Ga, whereas the Shuangtai zircons yield an upper intercept age of 763±33 Ma, identical to the timing of the Wudangshan volcanism within error, with few concordant grains of 1.9 and 0.86 Ga. Age spectra for the two river-sand samples are similar to those of the Yangping and Shuangtai Formations, respectively. It thus suggests that the Wudangshan strata are less than 780 Ma, whereas their major detrital zircon populations of 1.0–0.85 Ga and 830–780 Ma are consistent with timing of the Hannan magmatic activities along the northwestern margin of the South China Block. This suggests a Hannan or adjacent area provenance for the Wudangshan strata. The Wudang area is characterized by rift-related igneous events at ~755 and ~680 Ma, respectively, pointing to a tectono-magmatic history different from the Hannan area. It is inferred that the ~755 Ma magmatism is likely to indicate a separation of the South China Block from the supercontinent Rodinia, while the ~680 Ma event suggests a further split between the South Qinling and some unknown continent. | LING WenLi DUAN RuiChun LIU XiaoMing CHENG JianPing MAO XinWu PENG LianHong LIU ZaoXue YANG HongMei REN BangFang | 2010 | Chinese Science Bulletin2010，55，22： | 24 |
| 3 | 2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma显示文摘The incidence of papillary thyroid carcinoma(PTC)has exponentially increased in recent years.Papillary thyroid microcarcinoma(PTMC)accounts for the majority of the reported cases of PTC.The debates and crucial issues in PTMC management have received researchers'attention.To further improve the clinical management of PTMC in China, | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Li Gao Zhuming Guo Tao Huang Xiaoming Huang Xiaoming Li Yansong Lin Qinjiang Liu Xin Ni Yi Pan Jianwu Qin Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Daiwei Zhao Naisong Zhang ShengZhang Ying Zheng Jingqiang Zhu Dapeng Li Xiangqian Zheng 无 | 2017 | Cancer Biology & Medicine2017，14，3： | 23 |
| 4 | Zircon U-Pb dating on the Mesozoic volcanic suite from the Qingshan Group stratotype section in eastern Shandong Province and its tectonic significance显示文摘A geochronological study of zircon U-Pb on the volcanic rocks from the stratotype section of the Qingshan Group within the Jiaozhou Basin, eastern Shandong Province, is presented. The zircons were analyzed using the method of in situ ablation of a 193 nm excimer laser system coupled with an up to date ICP-MS system. Among the three formations of the Qingshan Group, zircons recovered from the lowest part of the Houkuang Fm. were dated at 106±2 Ma (95% confidence, the same below), whereas those from the lower and upper parts of the Shiqianzhuang Fm. were given ages of 105±4 Ma and 98±1 Ma, respectively. A spatially decreasing trend for the Mesozoic magmatic timing from west to east in the province is observed through comparing the data of this study with those by previous works on the Qingshan volcanic lavas occurring at western Shandong and within the Yishu fault zone. The Qingshan volcanic rocks are constituent of the 'Shoshonite Province' in East China. Exposed at most provinces of central East China along the Tan-Lu fault and the Yangtze fault zones, these volcanic suites are characterized by shoshonite and high-K calcalkalic rocks in lithology and thought to be correlated with the partial melting of continental mantle in genesis. It is also shown that the Qingshan potassic volcanic suite from eastern Shandong basins is distinctly younger than those from other ar-eas of the shoshonite province. By contrary, ages of the Mesozoic to Cenozoic alkaline basalts, sourced by asthenospheric mantle, from both northern Huaiyan basin and northern Dabie belt along the Tan-Lu fault zone and from the Ningwu, Lishui and Luzong basins along the Yangtze fault zone are observably older than those occurring within eastern Shandong. The revealed temporal and spatial patterns in magmatism for the two types of volcanic suites make an important geochronological con-straint on the Mesozoic to Cenozoic dynamic evolution model of the subcontinental lithosphere in East China. | LING WenLi XIE XianJun LIU XiaoMing CHENG JianPing | 2007 | Science China Earth Sciences2007，50，6： | 18 |
| 5 | Phosphorus oxoanion-intercalated layered double hydroxides for high-performance oxygen evolution显示文摘合理设计和为氧进化反应(OER ) 的有效、划算的电极的控制制造为探讨崭新的精力危机是批评的。有特定的夹层阴离子的镍铁分层的双氢氧化物(NiFe-LDHs )( 即磷酸盐,亚磷酸盐,和次磷酸盐) 被一个一起沉淀方法制作并且作为氧进化 electrocatalysts 调查了。磷 oxoanion 的置闰在一个碱的答案提高了 OER 活动;最佳的表演(即, 215 mV, 37.7 mV/dec 的一个小 Tafel 斜坡,和稳定的电气化学的行为的一个低发作潜力) 与设置次磷酸盐的 NiFe-LDH 催化剂被完成,在传统的设置碳酸盐的 NiFe-LDH 上的示威戏剧的改进以活动和耐久性。这提高的表演被归因于在设置的磷的 oxoanions 和分享边的瞬间 6 之间的相互作用(M = Ni, Fe ) 层,它修改表面 Ni 地点的电子结构。这个概念应该为更有效的基于 LDH 的氧进化 electrocatalysts 的设计是鼓舞人心的。 | Ma Luo Zhao Cai Cheng Wang Yongmin Bi Li Qian Yongchao Hao Li Li Yun Kuang Yaping Li Xiaodong Lei Ziyang HUO Wen Liu Hailiang Wang Xiaoming Sun Xue Duan | 2017 | Nano Research2017，10，5： | 12 |
| 6 | Transcriptional activation and phosphorylation of OsCNGC9 confer enhanced chilling tolerance in rice显示文摘Low temperature is a major environmental factor that limits plant growth and productivity.Although transient elevation of cytoplasmic calcium has long been recognized as a critical signal for plant cold tolerance,the calcium channels responsible for this process have remained largely elusive.Here we report that OsCNGC9,a cyclic nucleotide-gated channel,positively regulates chilling tolerance by mediating cytoplasmic calcium elevation in rice(Oryza sativa).We showed that the loss-of-function mutant of OsCNGC9 is defective in cold-induced calcium influx and more sensitive to prolonged cold treatment,whereas OsCNGC9 overexpression confers enhanced cold tolerance.Mechanistically,we demonstrated that in response to chilling stress,OsSAPK8,a homolog of Arabidopsis thaliana OST1,phosphorylates and activates OsCNGC9 to trigger Ca2+influx.Moreover,we found that the transcription of OsCNGC9 is activated by a rice dehydration-responsive element-binding transcription factor,OsDREB1A.Taken together,our results suggest that OsCNGC9 enhances chilling tolerance in rice through regulating cold-induced calcium influx and cytoplasmic calcium elevation. | Jiachang Wang Yulong Ren Xi Liu Sheng Luo Xiao Zhang Xin Liu Qibing Lin Shanshan Zhu Hua Wan Yang Yang Yu Zhang Bin Lei Chunlei Zhou Tian Pan Yongfei Wang Mingming Wu Ruonan jing Yang Xu Meng Han Fuqing Wu Cailin Lei Xiuping Guo Zhijun Cheng Xiaoming Zheng Yihua Wang Zhigang Zhao Ling Jiang Xin Zhang Yong-Fei Wang Haiyang Wang Jianmin Wan | 2021 | Molecular Plant2021，14，2： | 10 |
| 7 | Probing the seeded protocol for high-concentration preparation of silver nanowires显示文摘因为它的潜在的应用,高质量的银 nanowires (Ag NW ) 的大量生产具有重要重要性。卤素离子广泛地为 Ag NW 的合成被使用了;然而由于进异构的成核过程的深卓见的缺乏,通常喂数量的踪迹(例如[Cl -]< 0.25 公里) 被使用,它接着降低先锋的集中([Ag +]) 。这里,我们系统地调查了成核和 Ag NW 的生长行为并且断定异构的成核地点的数字由 AgCl 种子的全部的表面区域被决定,它在降水期间显示了在 Ag + 和 Cl - 的集中之间的一种线性关系。基于这机制,我们成功地与在以前报导的策略作为与那相比为一个水的系统更高为一个 polyol 系统和 5 次高 20 倍的 Ag + 集中生产了高质量的 Ag NW。而且由由控制 AgCl 种子的尺寸定制异构的成核地点,最后的 Ag NW 的直径能是甚至在高 Ag + 集中控制的井。基于机械学的理解,这合成策略能被扩大到另外的 AgX 种子(X = Br -, 我 - 并且 42-) 和基本原则能因此被使用帮助另外的产量很高的金属 NW 的合理合成做好悦耳的尺寸。 | Cheng Wang Baisong Cheng Haichuan Zhang Pengbo Wan Liang Luo Yun Kuang Xiaoming Sun | 2016 | Nano Research2016，9，5： | 8 |
| 8 | Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens显示文摘Naturally,resistant crop germplasms are important resources for managing the issues of agricultural product safety and environment deterioration.We found a spontaneous mutant of‘Newhall’navel orange(Citrus sinensis Osbeck)(MT)with broad-spectrum protections against fungal pathogens in the orchard,postharvest-storage,and artificial inoculation conditions.To understand the defense mechanism of MT fruit,we constructed a genome-scale metabolic network that integrated metabolome and transcriptome datasets.The coordinated transcriptomic and metabolic data were enriched in two sub-networks,showing the decrease in very long chain fatty acid(by 41.53%)and cuticular wax synthesis(by 81.34%),and increase in the synthesis of jasmonic acid(JA)(by 95.23%)and JA-induced metabolites such as 5-dimethylnobietin(by 28.37%)in MT.Furthermore,cytological and biochemical analyses confirmed that the response to fungal infection in MT was independent of wax deficiency and was correlated with the levels of jasmonates,and the expression of plant defensin gene PDF1.2.Results of exogenous application of MeJA and JA inhibitors such as propyl gallate proved that JA-mediated defense contributes to the strong tolerance against pathogens in MT.Our results indicated that jasmonate biosynthesis and signaling are stimulated by the fatty acid redirection of MT,and participate in the tolerance of pathogenic fungi. | Yizhong He Jingwen Han Runsheng Liu Yuduan Ding Jinqiu Wang Li Sun Xiaoming Yang Yunliu Zeng Weiwei Wen Juan Xu Hongming Zhang Xiang Yan Zhaoxing Chen Zuliang Gu Hong Chen Huanqing Tang Xiuxin Deng Yunjiang Cheng | 2018 | Horticulture Research2018，5，1： | 8 |
| 9 | SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target显示文摘Cytokine storm and multi-organ failure are the main causes of SARS-CoV-2-related death.However,the origin of excessive damages caused by SARS-CoV-2 remains largely unknown.Here we show that the SARS-CoV-2 envelope(2-E)protein alone is able to cause acute respiratory distress syndrome(ARDS)-like damages in vitro and in vivo. | Bingqing Xia Xurui Shen Yang He Xiaoyan Pan Feng-Liang Liu Yi Wang Feipu Yang Sui Fang Yan Wu Zilei Duan Xiaoli Zuo Zhuqing Xie Xiangrui Jiang Ling Xu Hao Chi Shuangqu Li Qian Meng Hu Zhou Yubo Zhou Xi Cheng Xiaoming Xin Lin Jin Hai-Lin Zhang Dan-Dan Yu Ming-Hua Li Xiao-Li Feng Jiekai Chen Hualiang Jiang Gengfu Xiao Yong-Tang Zheng Lei-Ke Zhang Jingshan Shen Jia Li Zhaobing Gao | 2021 | Cell Research2021，31，8： | 7 |
| 10 | Zircon SHRIMP U-Pb geochronology,geochemistry and petrogenesis of the upper Eocene Shuangmaidi peraluminous granite in Baoshan Block,Western Yunnan Terrain,southwestern China显示文摘The Baoshan Block is tectonically located in the middle segment of the Sibumasu plate.Granitic magmatism within the Baoshan Block has been considered weakly active due mainly to very limited exposures during the Himalaya orogenic episode.The geochronological study on the buried Shuangmaidi granite has confirmed the existence of the Cenozoic granitoids in the Baoshan Block.The present study indicates that:(1) It is medium-to coarse-grained two mica phyric granite,characterized by high SiO 2 (73.55%-77.16%) and low CaO (0.34%-1.38%) contents,with a total alkalis (K 2 O+Na 2 O) of 5.22%-8.03%,K 2 O/Na 2 O ratios of 0.24-1.79,and total rare earth elements (ΣREE) of the granite between 85 and 125 ppb.All samples are enriched in light REE and exhibit medium negative Eu anomalies;and they show pronounced negative anomalies in Ba,Sr,Ti,and Nb but significant positive anomalies in K,Rb,U,Th,and Pb on mantle-normalized trace element patterns,indicating typi-cally peraluminous to strongly peraluminous S-type granite.(2) The zircon SHRIMP U-Pb ages of the granite are 36.27±0.48 Ma for the samples from ZK7-1 and 35.78±0.49 Ma for those from ZK0-1,respectively.The similar zircon ages from these two drill cores may suggest that the granite samples come from the same buried pluton.(3) 206 Pb/204 Pb values of the granite vary from 20.115 to 25.359,207 Pb/204 Pb from 15.776 to 16.160,and 208 Pb/204 Pb from 39.236 to 41.285,showing the characteristics of radio-active lead anomaly of the upper crust.The (87 Sr/86 Sr) i values calculated on the average age of the two-mica orthoclase granite (36 Ma) range from 0.72524 to 0.77503 and ε Nd (t) values vary from 10.9 to 11.7.These data,along with the depleted-mantle Nd modal ages of 1.73-1.80 Ga,imply that the granites might have formed from partial melting of the Precambrian crystal basements.(4) On the Hf-Rb-Ta diagram,almost all the samples fall within the field of post-collision tectonic setting.The CaO/Na 2 O and Al 2 O 3/TiO 2 ratios suggest that the granitic magma may have formed from partial melting of clay-rich crustal materials with a pos-sible melting temperature of about 900°C and a possible crystallization temperature of 775-795°C.(5) During the post-collision of the Himalaya orogen,with the southeastward extrusion of the Indochina continent resulting from the continuous northward indentation of the India continent into the Asia,the Gaoligong Fault,as the western boundary of the Indochina continent,moved in the dextral strike-slip on a large scale to trigger partial melting of the thickened crust,and the peraluminous granitic magma from which the Shuangmaidi two-mica orthoclase granite derived was formed. | HUANG JingNing CHEN YongQing ZHAI XiaoMing LU YingXiang XIE YongFu CHENG ZhiZhong | 2011 | Science China Earth Sciences2011，54，7： | 7 |
| 11 | Audio Zero-Watermark Scheme Based on Discrete Cosine Transform-Discrete Wavelet TransformSingular Value Decomposition显示文摘Traditional watermark embedding schemes inevitably modify the data in a host audio signal and lead to the degradation of the host signal.In this paper,a novel audio zero-watermarking algorithm based on discrete wavelet transform(DWT),discrete cosine transform(DCT),and singular value decomposition(SVD) is presented.The watermark is registered by performing SVD on the coefficients generated through DWT and DCT to avoid data modification and host signal degradation.Simulation results show that the proposed zero-watermarking algorithm is strongly robust to common signal processing methods such as requantization,MP3 compression,resampling,addition of white Gaussian noise,and low-pass filtering. | Min Lei Yu Yang XiaoMing Liu MingZhi Cheng Rui Wang | 2016 | China Communications2016，13，7： | 7 |
| 12 | Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)显示文摘Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African countries.To reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries.The major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and watermelon.Comparative analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter gourd.Phylogenetic analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from M.charantia.Furthermore,we found that the remaining 166 M.charantia germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,respectively.This study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd. | Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu | 2020 | Horticulture Research2020，7，1： | 7 |
| 13 | Effect of cold rolling process on microstructure and mechanical properties of high strength β titanium alloy thin sheets显示文摘The microstructure and mechanical properties of Ti-3.5Al-5Mo-6V-3Cr-2Sn-0.5Fe high strength titanium alloy sheets prepared by unidirectional cold rolling and two-step cross cold rolling were investigated. Results showed that the β phase grains were refined significantly by cold rolling followed by solution treatment for a short time.Compared to unidirectional cold rolling, the short time solution treatment after two-step cross rolling could significantly reduce the non-uniformity of the microstructure of the alloy sheets. After aging treatment at 550 ℃,the anisotropy of the mechanical properties still existed in the unidirectional rolled sheets, and the tensile strength was highest along the rolling direction. After solution and aging treatment, the anisotropy of the mechanical properties of the two-step cross rolling process sheet was not obvious than unidirectional cold rolling,and alloy had good strength and plasticity matching. | Yan Ma Zhaoxin Du Xiaoming Cui Jun Cheng Guolong Liu Tianhao Gong Huimin Liu Xiaopeng Wang Yuyong Chen | 2018 | Progress in Natural Science:Materials International2018，28，6： | 6 |
| 14 | Characteristics of the Main Journal Bearings of an Engine Based on Non-linear Dynamics显示文摘Many simple nonlinear main journal bearing models have been studied theoretically,but the connection to existing engineering system has not been equally investigated.The consideration of the characteristics of engine main journal bearings may provide a prediction of the bearing load and lubrication.Due to the strong non-linear features in bearing lubrication procedure,it is difficult to predict those characteristics.A non-linear dynamic model is described for analyzing the characteristics of engine main journal bearings.Components such as crankshaft,main journals and con rods are found by applying the finite element method.Non-linear spring/dampers are introduced to imitate the constraint and supporting functions provided by the main bearing and oil film.The engine gas pressure is imposed as excitation on the model via the engine piston,con rod,etc.The bearing reaction force is calculated over one engine cycle,and meanwhile,the oil film thickness and pressure distribution are obtained based on Reynolds differential equation.It can be found that the maximum bearing reaction force always occurs when the maximum cylinder pressure arises in the cylinder adjacent to that bearing.The simulated minimum oil film thickness,which is 3 μm,demonstrates the reliability of the main journal bearings.This non-linear dynamic analysis may save computing efforts of engine main bearing design and also is of good precision and close connection to actual engine main journal bearing conditions. | NI Guangjian ZHANG Junhong CHENG Xiaoming | 2009 | Chinese Journal of Mechanical Engineering2009，22，5： | 6 |
| 15 | Realization of an Optimal Dynamic Geodetic Reference Frame in China:Methodology and Applications显示文摘China Geodetic Coordinate System 2000(CGCS2000)has been used for several years as a formal published reference frame.The coordinates of all global navigation satellite system(GNSS)stations in China need to be corrected to align with the CGCS2000 frame.Different strategies can be adopted for the realization of an optimal reference frame.However,different strategies lead to different results,with differences as great as several decimeters when GNSS station coordinates are transformed into CGCS2000-defined coordinates.The two common methods for the coordinate correction of a GNSS station are quasi-stable adjustment under CGCS2000 and plate movement correction,and the differences between their results can be greater than 10 cm.In this study,a statistic method called'supervised clustering'is applied to the selection of GNSS reference stations;a new scheme named'partition spacing'for the grouping of all processed GNSS stations is proposed;and the plate movement correction method is used to correct the coordinates of all GNSS stations from the GNSS epoch to the CGCS2000 epoch.The results from the new partitioning method were found to be significantly better than those from the conventional station-blocking approach.When coordinates from the stations without grouping were used as the standard,the accuracy of all the three-dimensional coordinate components from the new partitioning method was better than 2 mm.The root mean squares(RMSs)of the velocities in the x,y,and z directions resulting from the supervised clustering method were 0.19,0.45,and 0.32 mm∙a1,respectively,which were much smaller than the values of 0.92,0.72,and 0.97 mm∙a1 that resulted from the conventional approach.In addition,singular spectrum analysis(SSA)was used to model and predict the position nonlinear movements.The modeling accuracies of SSA were better than 3,2,and 5 mm in the east(E),north(N),and up(U)directions,respectively;and its prediction accuracies were better than 5 mm and 1 cm for the horizontal and vertical domains,respectively. | Pengfei Cheng Yingyan Cheng Xiaoming Wang Suqin Wu Yantian Xu | 2020 | Engineering2020，6，8： | 5 |
| 16 | Update China geodetic coordinate frame considering plate motion显示文摘China Geodetic Coordinate System 2000(CGCS2000),as the formal national coordinate reference frame,has been used for 20 years.The coordinates of all Global Navigation Satellite System(GNSS)stations in China need referring to this system.To this end,the first step is to align the coordinates of all stations,usually included in a regional GNSS network,with a given International Terrestrial Reference Frame(ITRF),then these coordinates are corrected to the CGCS2000 in consideration of plate movement.For a better alignment result,regional control stations are needed and their coordinates were estimated from the combination of constraint-free normal equation systems provided by several International GNSS Service(IGS)analysis centers.The effect in using these refined coordinates,which deter-mine a regional coordinate datum,on the alignment result should be evaluated by the coordinate corrections of the regional control stations to the regional coordinate datum,i.e.smaller corrections mean better alignments of the two associated frames.The test results show that the refined coordinates are more accurate than the ones calculated from the station’s velocity,and are well aligned with the ITRF2005.Moreover,for obtaining the coordinates of GNSS stations in an updated CGCS2000 frame,a gridded linear velocity field based on the estimated velocities at 1025 CGCS2000 stations was generated for China's Mainland using the optimal interpolation method,the inverse distance weighting,which is selected from five interpolation methods.The overall precisions of the constructed velocity field at all stations in the East(E)and,North(N)directions are 0.78 mm/a and 0.95 mm/a,respectively.For evaluating the accuracy of the updated CGCS2000 frame,monthly solutions for the coordinates of some CGCS2000 CORS stations in the ITRF2014 during the period from 2000.0 to 2018 were obtained and the Root Mean Square(RMS)of the differences between the coordinates corrected to the CGCS2000 and the known coordinates at these stations are about 2-3 cm. | Pengfei Cheng Yingyan Cheng Xiaoming Wang Yantian Xu | 2021 | Satellite Navigation2021，2，1： | 4 |
| 17 | High-throughput microfabrication of axially tunable helices显示文摘Helical structures exhibit novel optical and mechanical properties and are commonly used in different fields such as metamaterials and microfluidics. A few methods exist for fabricating helical microstructures, but none of them has the throughput or flexibility required for patterning a large surface area with tunable pitch. In this paper, we report a method for fabricating helical structures with adjustable forms over large areas based on multiphoton polymerization(MPP) using single-exposure, three dimensionally structured, self-accelerating, axially tunable light fields. The light fields are generated as a superposition of high-order Bessel modes and have a closed-form expression relating the design of the phase mask to the rotation rate of the beam. The method is used to fabricate helices with different pitches and handedness in the material SU-8. Compared to point-by-point scanning, the method reported here can be used to reduce fabrication time by two orders of magnitude, paving the way for adopting MPP in many industrial applications. | He Cheng Pooria Golvari Chun Xia Mingman Sun Meng Zhang Stephen M.Kuebler Xiaoming Yu | 2022 | Photonics Research2022，10，2： | 4 |
| 18 | Ectopic expression of VRT-A2 underlies the origin of Triticum polonicum and Triticum petropavlovskyi with long outer glumes and grains显示文摘Polish wheat (Triticum polonicum) is a unique tetraploid wheat species characterized by an elongated outer glume. The genetic control of the long-glume trait by a single semi-dominant locus, P1 (from Polish wheat), was established more than 100 years ago, but the underlying causal gene and molecular nature remain elusive. Here, we report the isolation of VRT-A2, encoding an SVP-clade MADS-box transcription factor, as the P1 candidate gene. Genetic evidence suggests that in T. polonicum, a naturally occurring sequence rearrangement in the intron-1 region of VRT-A2 leads to ectopic expression of VRT-A2 in floral organs where the long-glume phenotype appears. Interestingly, we found that the intron-1 region is a key ON/OFF molecular switch for VRT-A2 expression, not only because it recruits transcriptional repressors, but also because it confers intron-mediated transcriptional enhancement. Genotypic analyses using wheat accessions indicated that the P1 locus is likely derived from a single natural mutation in tetraploid wheat, which was subsequently inherited by hexaploid T. petropavlovskyi. Taken together, our findings highlight the promoter-proximal intron variation as a molecular basis for phenotypic differentiation, and thus species formation in Triticum plants. | Jing Liu Zhaoyan Chen Zhihui Wang Zhaoheng Zhang Xiaoming Xie Zihao Wang Lingling Chai Long Song Xuejiao Cheng Man Feng Xiaobo Wang Yanhong Liu Zhaorong Hu Jiewen Xing Zhenqi Su Huiru Peng Mingming Xin Yingyin Yao Weilong Guo Qixin Sun Jie Liu Zhongfu Ni | 2021 | Molecular Plant2021，14，9： | 4 |
| 19 | Synthesis and biological evaluation of 8-substituted and deglucuronidated scutellarin and baicalin analogues as antioxidant responsive element activators显示文摘Flavonoids are important bioactive dietary compounds, which are proved to be antioxidant responsive element (ARE) activators to defend against electrophilic toxicants and oxidative stress. The activators induce ARE gene transcription through Nrf2 factor, a major transcriptional stimulator of cytoprotective genes, relieved from a Keap1 complex. In this report, based on the structures of two flavonoids, scutellarin and baicalin, which are extracted from two common Chinese plants Dengzhanhua (Erigeron breviscapus (vant) Hand-Mazz) and Huangqin (Scutellaria baicalensis Georigi), respectively, we synthesized several 8-substituted and deglucuronidated analogues and identified the ARE activation effects of these flavonoids. We found that the Baicalin, deglucurnonidated Baicalin and diaza cyclopenta derivative were more active. Their dose-dependent upregulation activities of ARE and NQO1 and induction effects of Nrf2 were testified. The results presented that these three analogues had good upregulation effects on ARE, and they could be potentially utilized in relieving oxidative stress, upon further neuroprotective tests. | YANG Ping KONG XiangZhen CHENG ChangMei LI ChangYan YANG XiaoMing ZHAO Xing'E | 2011 | Science China Chemistry2011，54，10： | 3 |
| 20 | 2017 Chinese expert consensus on the clinical application ofserum marker for thyroid cancer显示文摘In recent years, the clinical incidence of thyroid cancer has been increasing year by year, and its risk assessment and clinical management methods have also been accordingly modified and constantly improved. There are great differences between the clinical diagnostic and therapeutic modes and disease management of thyroid cancer employed by various medical institutions in China, particularly with regard to the clinical application of serum marker of thyroid cancer. To this end, the China Anti-Cancer Association Thyroid Cancer Specialized Committee Chinese Association of Thyroid Oncology organized this compilation of ExpertConsensus on Clinical Application of Serum Marker of Thyroid Cancer to help and impel relevant clinical institutions and professionals to standardize clinical diagnosis, treatment, and long-term management of thyroid cancer, and to properly utilize the serum marker for scientific auxiliary clinical diagnosis and assessment of thyroid cancer before and after operation. | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Wei Cui Li Gao Zairong Gao Lin Guo Zhuming Guo Tao Huang Xiaoming Huang Yansong Lin Qinjiang Liu Xin Ni Jianwu Qin Li Ren Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Bin Zhang DaiweiZhao Ying Zheng Jingqiang Zhu Xiangqian Zheng 无 | 2018 | Cancer Biology & Medicine2018，15，4： | 3 |
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