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| 1 | RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。 | Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun | 2012 | Cell Research2012，22，5： | 66 |
| 2 | Long-term changes of phytoplankton community in Xiagu waters of Xiamen,China显示文摘Long-term changes of phytoplankton community by water sampling method in Xiagu Sea waters of Xiamen,China,were investigated in this study.Species composition of the phytoplankton community in these waters changed greatly since the 1950s.The numbers of Dinophyta species increased significantly,although Bacillariophyta species are generally dominant.The succession of dominant species in phytoplankton community is obvious: large-size dominant species such as Biddulphia sinensis of the 1950s were gradually replaced by small-size ones such as Cyclotella striata and Nitzschia closterium,and species that still maintain dominant such as Skeletonema costatum are also small ones,leading the whole phytoplankton community of smaller size.Cell density of phytoplankton community increased greatly,among which cell density of the most dominant species Skeletonema costatum have been increasing in exponent function.Margalef index of phytoplankton community decreased,indicating decline of biodiversity of the community,and dominant character of Skeletonema costatum increased.Generally,the structure of the entire phytoplankton community is becoming more and more singular and unstable,which makes the occurrence of red tides more frequent.The succession in the phytoplankton community is related to the long-term changes in marine environment,influenced by human activities and global climate changes,especially the increases of nutrient content. | CHEN Baohong XU Zhuhua ZHOU Qiulin CHEN Changping GAO Yahui YANG Shengyun JI Weidong | 2010 | Acta Oceanologica Sinica2010，29，6： | 14 |
| 3 | The Mechanism of Cortico-Striato-Thalamo-Cortical Neurocircuitry in Response Inhibition and Emotional Responding in Attention Deficit Hyperactivity Disorder with Comorbid Disruptive Behavior Disorder显示文摘The neurocircuitries that constitute the corticostriato-thalamo-cortical(CSTC) circuit provide a framework for bridging gaps between neuroscience and executive function in attention deficit hyperactivity disorder(ADHD), but it has been difficult to identify the mechanisms for regulating emotional problems from the understanding of ADHD comorbidity with disruptive behavior disorders(DBD). Research based on 'cool'' and 'hot''executive functional theory and the dual pathway models,which are thought of as applied response inhibition and delay aversion, respectively, within the neuropsychological view of ADHD, has shed light on emotional responding before and after decontextualized stimuli, while CSTC circuit-related domains have been suggested to explain the different emotional symptoms of ADHD with or without comorbid DBD. This review discusses the role of abnormal connections in each CSTC circuit, especially in the emotion circuit, which may be responsible for targeted executive dysfunction at the neuroscience level. Thus, the two major domains – abstract thinking(cool) and emotional trait(hot) – trigger the mechanism of onset of ADHD. | Yuncheng Zhu Xixi Jiang Weidong Ji | 2018 | Neuroscience Bulletin2018，34，3： | 12 |
| 4 | Speciation, distribution, and potential ecological risk assessment of heavy metals in Xiamen Bay surface sediment显示文摘Based on the survey of surface sediment in Xiamen Bay in October 2011, the speciation, distribution, and potential ecological risk assessment of heavy metals(Cu, Pb, Zn, Cd, and Cr) in this area were studied using the sequential extraction method and ecological risk assessment method. The results indicated:(1) the total concentrations of these heavy metals were influenced by runoff, industrial wastewater, and sewage, and were all higher in the coastal area than the offshore area while the highest area of Pb was a little farther away from the coastal water due to atmosphere deposition;(2) sequential extractions suggested that Cu was mainly composed with residual and Fe/Mn-oxide bound fractions, Pb was bound to Fe/Mn-oxide, Zn and Cr were dominated by residual, and Cd bound to exchangeable and carbonate fractions;(3) the order of migration and transformation sequence was Cd>Pb>Cu>Zn>Cr and the degree of pollution was Cd>Pb>Cu>Zn>Cr; and(4) the ratios of the secondary and primary phases showed that Zn and Cr were both clean, Cu may be polluted, Pb was moderately polluted, while Cd was heavily polluted. | LIN Cai LIU Yang LI Wenquan SUN Xiuwu JI Weidong | 2014 | Acta Oceanologica Sinica2014，33，4： | 11 |
| 5 | Hierarchical Ni-Co-S@Ni-W-O core-shell nanosheet arrays on nickel foam for high-performance asymmetric supercapacitors显示文摘镍钴硫化物(Ni-Co-S ) 由于他们的优秀传导性和高电气化学的电容在电子设备为申请吸引了广泛的注意。为了便于 Ni-Co-S,优秀的率能力和这些的周期的稳定性的大规模实际申请,混合物必须充分被利用。因此,镍泡沫上的层次 Ni-Co-S@Ni-W-O (Ni-Co-S-W ) 核心 / 壳混血儿 nanosheet 数组经由一个灵巧的三步的热水的方法此处被设计并且综合,由在氩空气下面在一个管状的炉子退火列在后面。混合结构直接作为一个自立的电极被装配,它展出了 1,988 F | Weidong He Zhifu Liang Keyu ji Qingfeng Sun Tianyou Zhai Xijin Xu | 2018 | Nano Research2018，11，3： | 7 |
| 6 | Environmental impact factors and mercury speciation in the sediment along Fujian and eastern Guangdong coasts显示文摘Concentrations of total mercury (THg) and methyl mercury (MeHg) were determined for 32 surface sediments collected along the coastal line of Fujian Province and eastern Guangdong Province. The spatial distributions of THg and MeHg and their environmental impact factors were investigated. The average concentrations of THg and MeHg in the sediments were 31.5 ng/g and 0.096 ng/g, respectively. Both sediment THg and MeHg concentrations showed relatively high value in the Minjiang Estuary and the coastal areas of Quanzhou and Putian. The concentrations overall decreased as the distance to the shoreline increased. The correlations among environmental impact factors and THg, MeHg were analyzed. The sediment THg concentration was highly correlated to the concentrations of organic matter, copper, total nitrogen (TN) and total phosphorus (TP), and significantly correlated to pH value of the bottom seawater and concentration of sediment sulfide. The sediment MeHg concentration was highly correlated to the concentrations of organic matter and copper, and significant correlated to the concentrations of sulfide, TN, TP and pH value of the bottom seawater. | ZHANG Yuanbiao HUO Yunlong LIU Xiyao KUANG Weiming YUAN Dongxing JI Weidong | 2013 | Acta Oceanologica Sinica2013，32，2： | 6 |
| 7 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 8 | Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma显示文摘Osteosarcoma is the most common primary bone sarcoma that mostly occurs in young adults. The causes of osteosarcoma are heterogeneous and still not fully understood. Identification of novel, important oncogenic factors in osteosarcoma and development of better, effective therapeutic approaches are in urgent need for better treatment of osteosarcoma patients. In this study, we uncovered that the oncogene MYC is significantly upregulated in metastastic osteosarcoma samples. In addition, high MYC expression is associated with poor survival of osteosarcoma patients. Analysis of MYC targets in osteosarcoma revealed that most of the osteosarcoma super enhancer genes are bound by MYC. Treatment of osteosarcoma cells with super enhancer inhibitors THZ1 and JQ1 effectively suppresses the proliferation, migration, and invasion of osteosarcoma cells. Mechanistically,THZ1 treatment suppresses a large group of super enhancer containing MYC target genes including CDK6 and TGFB2. These findings revealed that the MYC-driven super enhancer signaling is crucial for the osteosarcoma tumorigenesis and targeting the MYC/super enhancer axis represents as a promising therapeutic strategy for treatment of osteosarcoma patients. | Demeng Chen Zhiqiang Zhao Zixin Huang Du-Chu Chen Xin-Xing Zhu Yi-Ze Wang Ya-Wei Yan Shaojun Tang Subha Madhavan Weiyi Ni Zhan-peng Huang Wen Li Weidong Ji Huangxuan Shen Shuibin Lin Yi-Zhou Jiang | 2018 | Bone Research2018，6，2： | 5 |
| 9 | Spatial and temporal variability of colored dissolved organic matter absorption properties in the Taiwan Strait显示文摘Spatial and temporal variability of the absorption properties of colored dissolved organic matter (CDOM) in the Taiwan Strait was investigated in summer (July to August of 2006) and winter (from December 2006 to January of 2007) seasons. The CDOM absorption coefficient at 280 nm (a 280 ) showed a decreasing trend from nearshore to offshore areas while the spectral slope coefficient parameter calculated between wavelengths 275-295 nm (S 275 295 ) showed an increase, indicative of decreasing aromaticity and molecular weight of the CDOM. The average a 280 in winter (1.47 ± 0.50 m 1 ) was significantly higher than in summer (1.10 ± 0.41 m 1 ), while the average S 275 295 in winter (26.7 ± 5.2 μm 1 ) was significantly lower than in summer (30.6 ± 5.5 μm 1 ), demonstrating clear seasonal variation in CDOM abundance and properties in the Taiwan Strait. A three-end- member conservative mixing model showed that local terrestrial CDOM inputs from several rivers along the western coast were small (<5%). However, the distribution of CDOM in the Taiwan Strait is mainly controlled by water mass movement [i.e., the Zhe-min Coastal Current (ZCC) and the Kuroshio Branch Current (KBC) in winter and the South China Sea Water (SCSW) in summer]. Biological activity was also an important factor affecting the distribution of CDOM in the offshore region in summer months. | LIN Hui GUO Weidong HU Minghui LIN Cai JI Weidong | 2012 | Acta Oceanologica Sinica2012，31，5： | 4 |
| 10 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 11 | Long Noncoding RNA MALAT-1 is a New Potential Therapeutic Target for Castration-Resistant Prostate Cancer显示文摘 | Shancheng Ren Yawei Liu Weidong Xu Yi Sun Ji Lu Fubo Wang Min Wei Jian Shen Jianguo Hou Xu Gao Chuanliang Xu Jiaoti Huang Yi Zhao Yinghao Sun | 2013 | The Journal of Urology2013，，： | 2 |
| 12 | Precision in Liver Surgery显示文摘 | Jiahong Dong ShiZhong Yang Jianping Zeng Shouwang Cai Wenbin Ji Weidong Duan Aiqun Zhang Weizheng Ren Yinzhe Xu Jingwang Tan Xiangyang Bu Ning Zhang Xuedong Wang Xianqiang Wang Xiangfei Meng Kai Jiang Wanqing Gu Zhiqiang Huang | 2013 | Semin Liver Dis2013，，03： | 2 |
| 13 | Decorative near-infrared transmission filters featuring high-efficiency and angular-insensitivity employing ID photonic crystals显示文摘We present a new scheme for visibly-opaque but near-infrared-transmitting filters involving 7 layers based on one-dimensional ternary photonic crystals, with capabilities in reaching nearly 100% transmission efficiency in the near-infrared region. Different decorative reflection colors can be created by adding additional three layers while maintaining the near-infrared transmission performance. In addition, our proposed structural colors show great angular insensitivity up to ±60° for both transverse electric and transverse magnetic polarizations, which are highly desired in various fields. The facile strategy described here involves a simple deposit!on method for the fabrication, thereby having great potential in diverse applications such as image sensors, anti-counterfeit tag, and optical measurement systems. | Chengang Ji Chenying Yang Weidong Shen Kyu-Tae Lee Yueguang Zhang Xu Liu L.Jay Guo | 2019 | Nano Research2019，12，3： | 2 |
| 14 | A network-based gene-weighting approach for pathway analysis显示文摘古典算法瞄准与学习有关显著地识别生物小径调节经常减少的小径到基因集合,与对在一条定义小径以内的各种各样的基因的组成的非等价的明显的无知。我们这里设计了一个基于网络的方法以基因重量决定如此的非等价。决定的基因重量生物学上一致、柔韧联网不安。由把基因重量集成到古典基因设置分析,与为 “ 的随后的修正; over-counting”与多子单元蛋白质联系的偏爱,我们开发了一条新奇称基因的小径分析途径,在称为 “ 的一个 R 包裹实现了基因 Associaqtion 基于网络的小径 Analysis”(GANPA ) 。通过几 microarray 数据集的分析,包括 p53 数据集,气喘数据集和三乳癌数据集,我们证明我们的途径是生物学上可靠、可再现、对 microarray 因此有用的数据解释和假设产生。 | Zhaoyuan Fang Weidong Tian Hongbin Ji | 2012 | Cell Research2012，22，3： | 2 |
| 15 | Distribution of dissolved oxygen and causes of maximum concentration in the Bering Sea in July 2010显示文摘According to data obtained in the Bering Sea during the 4th Chinese National Arctic Research Expedition, the distribution of dissolved oxygen(DO) was studied, causes of its maximum concentration were discussed, and the relationships between DO and other parameters, such as salinity, temperature, and chlorophyll a were analyzed. The results showed DO concentration ranged from 0.53 to 12.05 mg/L in the Bering Sea basin. The upper waters contained high concentrations and the maximum occurred at the depth range from 20 to 50 m. The DO concentration decreased rapidly when the depth was deeper than 200 m and reached the minimum at the depth range from 500 to 1 000 m, and then increased slowly with the depth increasing but still kept at a low level. On the shelf, the DO concentration ranged from 6.53 to 16.63 mg/L with a mean value of 10.75 mg/L, and showed a characteristic of decreasing from north to south. The DO concentration was higher in the area between the Bering Sea and Lawrence Island and was lower in the southeast and southwest of Lawrence Island at the latitude of 62°N. The formation of maximum DO concentration was concerned with phytoplankton photosynthesis and formation of the themocline. To the south of Sta. B07 in the Bering Sea basin, the oxygen produced by photosynthesis permeated to the deeper water and the themocline made it difficult to exchange vertically, and to the north of Sta. B07, the maximum DO concentration occurred above the themocline due to phytoplankton activities. On the shelf, the oxygen produced by phytoplankton photosynthesis gathered at the bottom of the thermocline and formed the DO maximum concentration. In the Bering Sea basin, the DO and salinity showed a weak negative correlation(r=0.40) when the salinity was lower than 33.1, a significant negative correlation(r=0.92) when the salinity ranged from 33.1 to 33.7, and an irregular reversed parabola(r=0.95) when the salinity was greater than 33.7. | SUN Xiuwu LIN Cai CHEN Yong ZHANG Yuanbiao WANG Jigang JI Weidong | 2014 | Acta Oceanologica Sinica2014，33，6： | 2 |
| 16 | The cluster analysis of the water masses in western Taiwan Strait from hydrologic And chemical factors显示文摘TheclusteranalysisofthewatermassesinwesternTaiwanStraitfromhydrologicandchemicalfactors￥HuangZiqiangandJiWeidong(ReceivedAugu... | Huang Ziqiang and Ji Weidong (Third Institute of Oceanography, State Oceanic Administration, Xiamen 361005, China) | 1994 | Acta Oceanologica Sinica1994，13，4： | 2 |
| 17 | miR-133b acts as a tumor suppressor and negatively regulates FGFR1 in gastric cancer显示文摘 | Dacheng Wen Songhe Li Fujian Ji Hong Cao Weidong Jiang Jiaming Zhu Xuedong Fang | 2013 | Tumor Biology2013，，： | 2 |
| 18 | FESTAL: Fault-tolerant elastic scheduling algorithm for real time tasks in virtualized clouds 显示文摘 | Wang Ji Bao Weidong Zhu Xiaomin | 2015 | IEEE Trans on Computers2015，64，1： | 1 |
| 19 | Railway Engineering Experimental Teaching Research Based on the Combination of Field Experiment and Virtual Reality(VR)Technology——Taking Central South University as an Example显示文摘At present,rail transit is developing rapidly in the world,and this means new and changing requirements for the training of talents in railway engineering experiments.Given the current problems of limited laboratory/field instruments for railway engineering experimentsand the safety/administrative difficulties of going to the frontline of railway lines to teach railway engineering experiemnts in the field,the Department of Railway Engineering of Central South University tried to introduce virtual reality(VR)technology to teach students experiments in the field of railway engineering.Through the virtualized experimental methods,students can carry out railway engineering experiments such as;vehicle wheel pair off-axis experiments,track geometry and position detection,etc.by immersive means.It was observed that after performing virtual simulation experiments,students appeared conversant in subsequent field experiments.Thus,VR greatly improves the teaching efficiency of railway engineering experiments. | Zhiping Zeng Zhihui Zhu Weidong Wang Ping Lou Wei Li Bin Yan Hu Ji | 2020 | Review of Educational Theory2020，3，3： | 1 |
| 20 | Judicial Independence and the Values of Procedure显示文摘 | Ji Weidong | 2002 | Social Sciences in China ( A Quarterly Journal in Eng-lish)2002，，2： | 1 |
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