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| 1 | New Classification of Herlyn-Werner-Wunderlich Syndrome显示文摘 | Lan Zhu Na Chen Jia-Li Tong Wei Wang LeiZhang Jing-He Lang | 2015 | Chinese Medical Journal2015，，2： | 30 |
| 2 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 3 | The Qitai radio telescope显示文摘This study presents a general outline of the Qitai radio telescope(QTT)project.Qitai,the site of the telescope,is a county of Xinjiang Uygur Autonomous Region of China,located in the east Tianshan Mountains at an elevation of about 1800 m.The QTT is a fully steerable,Gregorian-type telescope with a standard parabolic main reflector of 110 m diameter.The QTT has adopted an umbrella support,homology-symmetric lightweight design.The main reflector is active so that the deformation caused by gravity can be corrected.The structural design aims to ultimately allow high-sensitivity observations from 150 MHz up to115 GHz.To satisfy the requirements for early scientific goals,the QTTwill be equipped with ultra-wideband receivers and large field-of-view multi-beam receivers.A multi-function signal-processing system based on RFSo C and GPU processor chips will be developed.These will enable the QTT to operate in pulsar,spectral line,continuum and Very Long Baseline Interferometer(VLBI)observing modes.Electromagnetic compatibility(EMC)and radio frequency interference(RFI)control techniques are adopted throughout the system design.The QTT will form a world-class observational platform for the detection of lowfrequency(nano Hertz)gravitational waves through pulsar timing array(PTA)techniques,pulsar surveys,the discovery of binary black-hole systems,and exploring dark matter and the origin of life in the universe.The QTT will also play an important role in improving the Chinese and international VLBI networks,allowing high-sensitivity and high-resolution observations of the nuclei of distant galaxies and gravitational lensing systems.Deep astrometric observations will also contribute to improving the accuracy of the celestial reference frame.Potentially,the QTT will be able to support future space activities such as planetary exploration in the solar system and to contribute to the search for extraterrestrial intelligence. | Na Wang Qian Xu Jun Ma Zhiyong Liu Qi Liu Hailong Zhang Xin Pei Maozheng Chen Richard N.Manchester Kejia Lee Xingwu Zheng Hans J.Kärcher Wulin Zhao Hongwei Li Dongwei Li Martin Süss Matthias Reichert Zhongyi Zhu Congsi Wang Mingshuai Li Rui Li Ning Li Guljaina Kazezkhan Wenming Yan Gang Wu Lang Cui Ming Zhang Haitao Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，8： | 14 |
| 4 | Preparation and phase change performance of Na_2HPO_4·12H_2O@poly(lactic acid) capsules for thermal energy storage显示文摘Micro-encapsulated phase-change materials(micro PCMs) with Na_2 HPO_4·12 H_2 O encapsulated in poly(lactic acid)(PLA) shell were prepared by a solvent evaporation–precipitation method that involves the use of a coaxial needle. The effects of PLA concentration, stirring speed, injection rate of core and shell solutions, and polyvinyl alcohol(PVA) concentration on phase change properties were investigated. The thermal properties of microP CMs were characterized by differential scanning calorimetry(DSC). The capsules prepared under the optimal conditions are about 2 mm in diameter and show a latent heat of up to 122.2 J·g^(-1). | Na Fan Lang Chen Guoyong Xie Donghong Yin Chak-Tong Au Shuangfeng Yin | 2019 | Chinese Journal of Chemical Engineering2019，27，3： | 4 |
| 5 | Effectiveness of flesh-moistening paste in psoriasis vulgaris patients with symptom pattern of blood stasis:a randomized and parallel-controlled trial显示文摘OBJECTIVE:To evaluate the efficacy and safety of flesh-moistening paste for treating psoriasis vulgaris in patients with blood stasis pattern in terms of Traditional Chinese Medicine(TCM).METHODS:Eudipleural rashes on both the left and right side of the same patients with psoriasis vulgaris,diagnosed via TCM as blood stasis pattern,were selected as the targeted skin lesions.A randomized,double-blind,parallel-controlled,multicenter controlled trial was conducted.The targeted skin lesions were categorized into either the treatment or control group.The treatment group used the flesh-moistening paste;the control group used a placebo.Both the paste and the placebo were topically applied twice daily for eight weeks.The patients were examined biweekly to evaluate the effects.The two groups were compared in terms of the psoriasis area and severity index(PASI)of the targeted skin lesions,which is scored according to erythema,desquamation,infiltration,area,pruritus,and improvement of skin barrier function.Adverse events were recorded during the study period.SPSS 21.0 was used to analyze the data.RESULTS:Fifty-six patients were enrolled between February 2016 and October 2017.Two were complicated by cardio-cerebrovascular disease and were excluded;thus,54 outpatients were finally enrolled in the study.Four dropped out during the study period:three failed to complete their follow-up visits for unknown reasons,and one exited due to an adverse event.The final trial comprised 50 of the 56 originally selected patients,with a 92.6%completion rate.After 8 weeks of treatment,the targeted skin lesion scores differed significantly(P<0.05).The PASI scores of the targeted skin lesions differed significantly beginning at week 6(P<0.05).The treatment group presented better results than those of the control group.Only one patient had an adverse reaction associated with the treatment.Improvements in skin barrier function differed significantly(P<0.05).CONCLUSION:The flesh-moistening paste demonstrated a reliable curative effect and safety for treating psoriasis vulgaris in patients with blood stasis patterns.The topical paste improved the barrier function of the skin lesions. | Guo Xinwei Lang Na Li Guanru Li Ping Qu Jianhua Zhou Dongmei Wang Ping Cang Zhang Deng BingXu Lou Weihai Xu Jingna Lan Haibing Liu Yumin Zhang Weishu Sun Liyun | 2020 | Journal of Traditional Chinese Medicine2020，40，6： | 4 |
| 6 | Marginal fit of ce- mented and screw-retained crowns incorporated on the Straumann(ITI)Dental Implant System: an in vitro study 显示文摘 | Tosches NA Br/i gger U Lang NP | 2009 | Clin Oral Implants Res2009，20，1： | 1 |
| 7 | A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo 显示文摘 | Huizenga NA Koper JW De lange P | 1998 | Clin Endocr Metabol1998，83，1： | 1 |
| 8 | A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo显示文摘 | Huiznea NA Kopper IW de Lange P | 1998 | J Clin Endocrinol Metab1998，83，： | 1 |
| 9 | Dynamic force feedback in a virtual knee palpation显示文摘 | Langrana NA Burdear G Lange K | 1994 | ArtifIntell Med1994，6，4： | 1 |
| 10 | Plastid and nuclear phylogenomic incongruences and biogeographic implications of Magnolia s.l.(Magnoliaceae)显示文摘Magnoliaceae,an assemblage of early diverged angiosperms,comprises two subfamilies,speciose Magnolioideae with approximately 300 species in varying numbers of genera and monogeneric Liriodendroideae with two species in Liriodendron L.This family occupies a pivotal phylogenetic position with important insights into the diversification of early angiosperms,and shows intercontinentally disjunct distribution patterns between eastern Asia and the Americas.Widespread morphological homogeneity and slow substitution rates in Magnolia L.s.l.resulted in poorly supported phylogenetic relationships based on morphology or molecular evidence,which hampers our understanding of the genus,temporal and spacial evolution.Here,based on the newly generated genome skimming data for 48 Magno/fa s.l.species,we produced robust/Vlagno/kj phylogenies using genome-wide markers from both plastid genomes and single nucleotide polymorphism data.Contrasting the plastid and nuclear phylogenies revealed extensive cytonuclear conflicts in both shallow and deep relationships.ABBA-BABA and PhyloNet analyses suggested hybridization occurred within sect.Yulania,and sect.Magnolia,which is in concordance with the ploidy level of the species in these two sections.Divergence time estimates and biogeographic reconstruction indicated that the timing of the three tropical Magnolia disjunctions coincided with the mid-Eocene cooling climate and/or late Eocene climate deterioration,and two temperate disjunctions occurred much later,possibly during the warm periods of the Miocene,hence supporting the boreotropical flora concept of Magnolia s.l. | Shan-Shan Dong Ya-Ling Wang Nian-He Xia Yang Liu Min Liu Lian Lian Na Li Ling-Fei Li Xiao-An Lang Yi-Qing Gong Lu Chen Ernest Wu Shou-Zhou Zhang | 2022 | Journal of Systematics and Evolution2022，60，1： | 1 |
| 11 | Role of the endo- thelium in the vascular effects of the thrombin receptor( protease - activated receptor type 1 ) in humans 显示文摘 | Gudmundsd6ttir IJ Lang NN Boon NA | 2008 | J Am Coil Cardiol2008，51，18： | 1 |
| 12 | Sub-nanometer ultrathin epitaxy of AlGaN and its application in efficient doping显示文摘Solving the doping asymmetry issue in wide gap semiconductors is a key dificulty and long-standing challenge for device applications.Here,a desorption-tailoring strategy is proposed to juggle the carrier concentration and transport.Specific to the p-doping issue in Al-rich AlGaN,self-assembled p-AlGaN superlattices with an average Al composition of over 50%are prepared by adopting this approach.The hole concentration as high as 8.1×10^(18)cm^(-3)is thus realized at room temperature,which is attributed to the signifcant reduction of effective Mg activation energy to 17.5 meV through modulating the activating path,as well as the highlighted Mg surface-incorporation by an intentional interruption for desorption.More importantly,benefting from the constant ultrathin barrier thickness of only three monolayers via this approach,vertical miniband transport of holes is verifed in the p-AlGaN superlattices,greatly satisfying the demand of hole injection in device application.280 nm deep-ultraviolet light emitting diodes are then fabricated as a demo with the desorption-tailored Al-rich p-AlGaN superlattices,which exhibit a great improvement of the carrier injection efficiency and light extraction efficiency,thus leading to a 55.7%increase of the light output power.This study provides a solution for p-type doping of Al-rich AlGaN,and also sheds light on solving the doping asymmetry issue in general for wide-gap semiconductors. | Jiaming Wang Mingxing Wang Fujun Xu Baiyin Liu Jing Lang Na Zhang Xiangning Kang Zhixin Qin Xuelin Yang Xinqiang Wang Weikun Ge Bo Shen | 2022 | Light(Science & Applications)2022，11，4： | 1 |
| 13 | Evolutionary mechanism of b-oriented TS-1 film on porous α-Al_2O_3 supported chitosan surface in hydrothermal reactions显示文摘The acid-base titration,atomic force microscopy(AFM),contact angle technique,energy dispersive X-ray(EDX)and electron probe microanalysis(EPMA)were performed to check the existence of the gel-layer on the chitosan surface after it was dipped in aqueous TPAOH solution as well as in TS-1 synthesis solution.The evolution of TS-1 monolayer and multi-layered film on the chitosan surface was studied using SEM imaging at different stages during hydrothermal reactions.Experimental evidence for the formation mechanism of supported zeolite films and membranes revealed that a gel-layer enriched with TPA cations and TS-1 precursors was first formed on the chitosan surface,followed by the nucleation within the gel-layer especially on the chitosan surface.The nuclei formed on the chitosan surface were further transformed into crystalline particles and TS-1 crystal grains.The nuclei beyond the chitosan surface subsequently grew up,leading to the formation of multi-layered TS-1 film with preferential b-orientation.The result is significant for engineering the microstructure of supported zeolite films and membranes in hydrothermal reactions. | LIU XiuFeng WANG XiaoDong NA Ping JIANG HaiYang LANG Lin ZHAO HongShe ZHANG BaoQuan | 2010 | Chinese Science Bulletin2010，55，27： | 1 |
| 14 | Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers-Smoking,thrombin,and vascular responses in vivo显示文摘 | Lang NN Guomundsdottir IJ Boon NA | 2008 | J Am Coll Cardiol2008，52，1： | 1 |
| 15 | Recognition dynamics up to microsconds revealed from an RDC-derived ubiquitin ensemble in solution显示文摘 | Lange OF Lakomek NA Far e C | 2008 | Science2008，320，5882： | 1 |
| 16 | SOCS3 regulates the plasticity of gp130 signaling显示文摘 | Pauleau nA L Parganas E | 2003 | Nat Immunol2003，4，6： | 1 |
| 17 | Role of the endothelium in the vascular effects of the thrombin receptor (protease-activated receptor type 1) in humans显示文摘 | Gudmundsdóttir IJ Lang NN Boon NA | 2008 | J Am Cell Cardiol2008，51，18： | 1 |
| 18 | Human adrenocorticotropin-secreting pituitary adenomas show frequent loss of heterozygosity at the glucocorticoid receptor gene locus显示文摘 | Huizenga NA de Lange P Koper JW | 1998 | J Clin Endocrinol Metab1998，83，3： | 1 |
| 19 | Rapid dissociation and on-site saturation evaluation of methane hydrate sediment samples for natural gas hydrate exploitation显示文摘Natural gas hydrate is a kind of clean energy with huge reserves,and the saturation(volume percentage of hydrate in pore space of sediments)is the key parameter for determining whether the reservoir is worthy of exploitation.In this work,rapid hydrate dissociation by the combination of heat injection and NaCl inhibitor addition was studied,and an on-site evaluation method for hydrate saturation in sediment samples was proposed by using a core sampler to transfer hydrate samples under pressure.The results showed that the average gas production rate per unit volume was increased significantly to reach 7.22 L/Lr$min-1 by the injection of NaCl aqueous solution with 50.9C,which was attributed to the increase of the chemical potential to further accelerate the rate of hydrate dissociation in the presence of NaCl.Furthermore,for the measurement of methane hydrate samples saturation with a volume of 673 cm3(which contained 1.4 mol hydrates with the saturation of 58%),hydrate saturation could be accurately achieved within 30 min with a relative error lower than 11.7%This work may provide new thoughts for on-site saturation evaluation and rapid dissociation of hydrate samples during natural gas hydrate exploitation. | Shuanshi Fan Kai Guo Yanhong Wang Xuemei Lang Na Wei Qingping Li | 2021 | Petroleum2021，7，4： | 1 |
| 20 | A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo显示文摘 | Huizenga NA Koper JW De Lange P | 1998 | J Clin Endocrinol Metab1998，83，1： | 1 |
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