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| 1 | Surrogate-Assisted Particle Swarm Optimization Algorithm With Pareto Active Learning for Expensive Multi-Objective Optimization显示文摘For multi-objective optimization problems, particle swarm optimization(PSO) algorithm generally needs a large number of fitness evaluations to obtain the Pareto optimal solutions. However, it will become substantially time-consuming when handling computationally expensive fitness functions. In order to save the computational cost, a surrogate-assisted PSO with Pareto active learning is proposed. In real physical space(the objective functions are computationally expensive), PSO is used as an optimizer, and its optimization results are used to construct the surrogate models. In virtual space, objective functions are replaced by the cheaper surrogate models, PSO is viewed as a sampler to produce the candidate solutions. To enhance the quality of candidate solutions, a hybrid mutation sampling method based on the simulated evolution is proposed, which combines the advantage of fast convergence of PSO and implements mutation to increase diversity. Furthermore, ε-Pareto active learning(ε-PAL)method is employed to pre-select candidate solutions to guide PSO in the real physical space. However, little work has considered the method of determining parameter ε. Therefore, a greedy search method is presented to determine the value ofεwhere the number of active sampling is employed as the evaluation criteria of classification cost. Experimental studies involving application on a number of benchmark test problems and parameter determination for multi-input multi-output least squares support vector machines(MLSSVM) are given, in which the results demonstrate promising performance of the proposed algorithm compared with other representative multi-objective particle swarm optimization(MOPSO) algorithms. | Zhiming Lv Linqing Wang Zhongyang Han Jun Zhao Wei Wang | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，3： | 13 |
| 2 | The net primary productivity of Mid-Jurassic peatland and its control factors: Evidenced by the Ordos Basin显示文摘Using the large-scale thick 4# coal seam from the Mid-Jurassic in the southern Ordos Basin as an example, this paper studied the net primary productivity(NPP) level of the Mid-Jurassic peatland, and discussed its control factors. Geophysical logging signals were used for a spectrum analysis to obtain the Milankovitch cycle parameters in coal seam. These were then used to calculate the accumulation rate of the residual carbon in 4# coal seam. The carbon loss can be calculated according to the density and residual carbon content of 4# coal seam. Then, the total carbon accumulation rate of the peatland was further derived, and the NPP of peatland was determined. The results show that the NPP of MidJurassic peatland is higher than that of Holocene at the same latitude. Comprehensive analysis indicates that the temperature, carbon dioxide and oxygen levels in atmosphere are the main control factors of the NPP of Mid-Jurassic peatland. | Wang Dongdong Yan Zhiming Liu Haiyan Lv Dawei Hou Yijun | 2018 | International Journal of Mining Science and Technology2018，28，2： | 7 |
| 3 | Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling显示文摘室的肥大是心血管的疾病的事件的一个强大、独立的预言者。低剂量的乙酰水杨酸酸(阿司匹林) 的脉管的性质通过血小板 cyclooxygenase 的不可逆的抑制提供心血管的好处 1;然而,可能的 anti-hypertrophic 性质和阿司匹林的潜在的机制没详细被调查。在这研究,健康野类型的雄的老鼠随机被划分成三个组并且使遭到了到横向的大动脉的收缩(TAC ) 或假冒的操作。操作 TAC 的老鼠与低剂量的阿司匹林的人的等价物被对待(10 mg 吗? | Samuel Chege Gitau Xuelian Li Dandan Zhao Zhenfeng Guo Haihai Liang Ming Qian Lifang Lv Tianshi Li Bozhi Xu Zhiguo Wang Yong Zhang Chaoqian Xu Yanjie Lu Zhiming Du Hongli Shan Baofeng Yang | 2015 | Frontiers of Medicine2015，9，4： | 6 |
| 4 | Geoscience knowledge graph in the big data era显示文摘Since the beginning of the 21 st century,the geoscience research has been entering a significant transitional period with the establishment of a new knowledge system as the core and with the drive of big data as the means.It is a revolutionary leap in the research of geoscience knowledge discovery from the traditional encyclopedic discipline knowledge system to the computer-understandable and operable knowledge graph.Based on adopting the graph pattern of general knowledge representation,the geoscience knowledge graph expands the unique spatiotemporal features to the Geoscience knowledge,and integrates geoscience knowledge elements,such as map,text,and number,to establish an all-domain geoscience knowledge representation model.A federated,crowd intelligence-based collaborative method of constructing the geoscience knowledge graph is developed here,which realizes the construction of high-quality professional knowledge graph in collaboration with global geo-scientists.We also develop a method for constructing a dynamic knowledge graph of multi-modal geoscience data based on in-depth text analysis,which extracts geoscience knowledge from massive geoscience literature to construct the latest and most complete dynamic geoscience knowledge graph.A comprehensive and systematic geoscience knowledge graph can not only deepen the existing geoscience big data analysis,but also advance the construction of the high-precision geological time scale driven by big data,the compilation of intelligent maps driven by rules and data,and the geoscience knowledge evolution and reasoning analysis,among others.It will further expand the new directions of geoscience research driven by both data and knowledge,break new ground where geoscience,information science,and data science converge,realize the original innovation of the geoscience research and achieve major theoretical breakthroughs in the spatiotemporal big data research. | Chenghu ZHOU Hua WANG Chengshan WANG Zengqian HOU Zhiming ZHENG Shuzhong SHEN Qiuming CHENG Zhiqiang FENG Xinbing WANG Hairong LV Junxuan FAN Xiumian HU Mingcai HOU Yunqiang ZHU | 2021 | Science China Earth Sciences2021，64，7： | 4 |
| 5 | Polarization-enhanced AlGaN solar-blind ultraviolet detectors显示文摘AlGaN solar-blind ultraviolet detectors have great potential in many fields,although their performance has not fully meet the requirements until now.Here,we proposed an approach to utilize the inherent polarization effect of AlGaN to improve the detector performance.AlGaN heterostructures were designed to enhance the polarization field in the absorption layer,and a high built-in field and a high electron mobility conduction channel were formed.As a result,a high-performance solar-blind ultraviolet detector with a peak responsivity of 1.42 A/W at 10 V was achieved,being 50 times higher than that of the nonpolarization-enhanced one.Moreover,an electron reservoir structure was proposed to further improve the performance.A higher peak responsivity of 3.1 A/W at30 V was achieved because the electron reservoir structure could modulate the electron concentration in the conduction channel.The investigation presented here provided feasible approaches to improve the performance of the AlGaN detector by taking advantage of its inherent property. | Ke Jiang Xiaojuan Sun Zi-Hui Zhang Jianwei Ben Jiamang Che Zhiming Shi Yuping Jia Yang Chen Shanli Zhang Wei Lv Dabing Li | 2020 | Photonics Research2020，8，7： | 3 |
| 6 | Discussion about shortening the time of die change to improve stamping production efficiency 显示文摘 | Shao Huiqiang Lv Zhiming | 2007 | Shanghai Auto2007，，9： | 1 |
| 7 | Telomerase Reverse Transcriptase Gene Promoter Mutations Help Discern the Origin of Urogenital Tumors: A Genomic and Molecular Study显示文摘 | Song Wu Peide Huang Chong Li Yi Huang Xianxin Li Yongqiang Wang Chao Chen Zhaojie Lv Aifa Tang Xiaojuan Sun Jingxiao Lu Weiping Li Jie Zhou Yaoting Gui Fangjian Zhou Daping Wang Zhiming Cai | 2013 | European Urology2013，，： | 1 |
| 8 | Elevated expression of CAPON and neuronal nitric oxide synthase in the sciatic nerve of rats following constriction injury显示文摘 | Zhiming Cui Qingshan Lv Meijuan Yan Chun Cheng Zhiqin Guo Junling Yang Mengling Chen Yinyin Xia Li Zhang Aiguo Shen | 2010 | The Veterinary Journal2010，，3： | 1 |
| 9 | An Economic Modd for Power Control in Wireless CDMA Date Networks显示文摘 | Yin Zhiming Xie Jianying Lv Pingbao | 2003 | Proceedings of ICCT2003，，： | 1 |
| 10 | Tunable piezoelectric and ferroelectric responses of Al1-xScxN:The role of atomic arrangement显示文摘In this study,we present first-principles investigations of the atomic structure of Al_(1-x)Sc_(x)N and its influence on its piezoelectric and ferroelectric properties.The unbiased structure searching revealed that Al_(1-x)Sc_(x)N with phase separation feature,where Al N and Sc N form a layered structure with different symmetries,is more stable than the corresponding wurtzite structure.The piezoelectric response of Al_(1-x)Sc_(x)N is strongly dependent on the atomic arrangements;in particular,Al_(0.5)Sc_(0.5)N with a wurtzite structure exhibits a large positive e33of 4.79 C/m^(2),whereas Al_(0.5)Sc_(0.5)N with a phase separation structure exhibits a negative e33of-0.67 C/m^(2).Moreover,the ferroelectric switching of Al_(1-x)Sc_(x)N demonstrated two distinct pathways for the wurtzite and phase separation structures,and the spontaneous polarization thus calculated exhibits entirely different values.Accordingly,we demonstrated that Al_(1-x)Sc_(x)N with a phase separation structure exhibits a low polarization switching barrier of 0.15 e V/f.u.and a large spontaneous polarization of-0.77 C/m^(2);thus,it can serve as a novel Al_(1-x)Sc_(x)N-based ferroelectric material.As the dipoles in Al_(1-x)Sc_(x)N with a phase separation structure are localized in the AlN region,they are individually switchable at no domain wall energy cost and are stable against extrinsic effects. | Hang Zang Zhiming Shi Mingrui Liu Yuping Jia Ke Jiang Jianwei Ben Yang Chen Shunpeng Lv Xiaojuan Sun Dabing Li | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，7： | 0 |
| 11 | Detection of the expression of heat shock protein 70 using quantum dots as fluorescence probe in human renal carcinoma显示文摘 | Cai Lv Jie Zhang Zhiming Bai Huan Yang Xiaobin Zhang | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，3： | 0 |
| 12 | Kinetics Research on In-situ Rapid Dechlorination of 1,4-dichlorobenzene by Microwave-assisted Raney Ni-Al Alloy Catalyst显示文摘[Objective]The research aimed to study rapid dechlorination kinetics of 1,4-dichlorobenzene(1,4-DCB)by microwave-assisted Raney Ni-Al alloy catalyst.[Method]Microwave-assisted Raney Ni-Al alloy catalyst was used for dechlorination of chlorobenzene(CB)and 1,4-DCB to analyze dechlorination kinetics of 1,4-DCB.[Result]Reductive dechlorination reaction of 1,4-DCB by microwave-assisted Raney Ni-Al alloy catalyst was in accordance of the two-order reaction kinetics.Reaction rate constants of 1,4-DCB dechlorination at 35 and 50℃were 0.037 6 and0.151 mol/(L·min),and the activation energy was 76.66 kJ/mol.By microwave-assisted Raney Ni-Al alloy catalyst,dechlorination rate of 1,4-DCB reached 90%at 10 min and 35℃.Moreover,two chlorine atoms were removed simultaneously,reaching the target of efficient dechlorination.[Conclusion]Dechlorination of polychlorinated organic compounds by microwave-assisted Raney Ni-Al alloy catalyst obtained good effect. | Zhiming Chen Zhaoyu Mo Baoying Lv Hong Xie Li Tang | 2013 | Meteorological and Environmental Research2013，4，9： | 0 |
| 13 | Cancer cell employs a microenvironmental neural signal transactivating nucleus-mitochondria coordination to acquire stemness显示文摘Cancer cell receives extracellular signal inputs to obtain a stem-like status,yet how tumor microenvironmental(TME)neural signals steer cancer stemness to establish the hierarchical tumor architectures remains elusive.Here,a pan-cancer transcriptomic screening for 10852 samples of 33 TCGA cancer types reveals that cAMP-responsive element(CRE)transcription factors are convergent activators for cancer stemness.Deconvolution of transcriptomic profiles,specification of neural markers and illustration of norepinephrine dynamics uncover a bond between TME neural signals and cancer-cell CRE activity.Specifically,neural signal norepinephrine potentiates the stemness of proximal cancer cells by activating cAMP-CRE axis,where ATF1 serves as a conserved hub.Upon activation by norepinephrine,ATF1 potentiates cancer stemness by coordinated trans-activation of both nuclear pluripotency factors MYC/NANOG and mitochondrial biogenesis regulators NRF1/TFAM,thereby orchestrating nuclear reprograming and mitochondrial rejuvenating.Accordingly,single-cell transcriptomes confirm the coordinated activation of nuclear pluripotency with mitochondrial biogenesis in cancer stem-like cells.These findings elucidate that cancer cell acquires stemness via a norepinephrine-ATF1 driven nucleus-mitochondria collaborated program,suggesting a spatialized stemness acquisition by hijacking microenvironmental neural signals. | Bin He Rui Gao Shasha Lv Ailin Chen Junxiu Huang Luoxuan Wang Yunxiu Feng Jiesi Feng Bing Liu Jie Lei Bing Deng Bin He Bai Cui Fei Peng Min Yan Zifeng Wang Eric W-F Lam Bilian Jin Zhiming Shao Yulong Li Jianwei Jiao Xi Wang Quentin Liu | 2023 | Signal Transduction and Targeted Therapy2023，8，8： | 0 |
| 14 | Transformer-Based Macroscopic Regulation for High-Speed Railway Timetable Rescheduling显示文摘Unexpected delays in train operations can cause a cascade of negative consequences in a high-speed railway system.In such cases,train timetables need to be rescheduled.However,timely and efficient train timetable rescheduling is still a challenging problem due to its modeling difficulties and low optimization efficiency.This paper presents a Transformer-based macroscopic regulation approach which consists of two stages including Transformer-based modeling and policy-based decisionmaking.Firstly,the relationship between various train schedules and operations is described by creating a macroscopic model with the Transformer,providing the better understanding of overall operation in the high-speed railway system.Then,a policy-based approach is used to solve a continuous decision problem after macro-modeling for fast convergence.Extensive experiments on various delay scenarios are conducted.The results demonstrate the effectiveness of the proposed method in comparison to other popular methods. | Wei Xu Chen Zhao Jie Cheng Yin Wang Yiqing Tang Tao Zhang Zhiming Yuan Yisheng Lv Fei-Yue Wang | 2023 | IEEE/CAA Journal of Automatica Sinica2023，10，9： | 0 |
| 15 | A specific assay for JmjC domain-containing lysine demethylase and its application to inhibitor screening显示文摘Dear Editor, Chromatin is the macromolecular complex of DNA and histone proteins, which provides the scaffold for the packaging of our entire genome. In the basic unit of chromatin, the nucleosomes contain 147 base pairs of DNA, which is wrapped around a histone octamer, with two each of histones H2A, H2B, H3, and H4. Several types of post-translational modifications, including acetylation, phosphorylation, ubiquitination, and methylation, are possible on the tails of histones (Zhang et al., 2015). Combinations of these modifications determine the chromatin structure and transcriptional regulation of genes. Histone methylation is highlighted because of the specific dynamics related to gene regulation. Aberrant histone methylation has been observed in many types of tumors (Albert and Helin, 2010) and may contribute to the neoplastic transformation of cells (Chi et al., 2010). Histone lysine methylation is regulated by two classes of enzymes that have opposing activities: histone lysine methyltransferases (KMTs) and histone lysine demethylases (KDMs). To date, a number of mammalian KDMs have been discovered (Kooistra and Helin, 2012), and they have been separated into two classes: flavin adenine dinucleotide dependent oxidases, which were first discovered in 2004 (Shi et al., 2004), and Jumonji-C (JmjC) domain-containing enzymes, first identified in 2006 (Tsukada et al., 2006). | He Wen Guo Li Yongcan Chen Meiting Li Yafei Lv Zhiming Li Yinglu Li Tianyun Hou Hui Wang Chaohua Liu Xiaopeng Lu Qian Zhu Yantao Bao Ge Liu Xiaofan Li Wei-Guo Zhu | 2019 | Science China(Life Sciences)2019，62，10： | 0 |
| 16 | The deep background of large-scale,Mesozoic Cu-Au-W metallogenesis in northeastern South China:Constraints from Yingshan-Changshan wide-angle seismic reflection/refraction data显示文摘To investigate the geodynamic processes of Mesozoic large-scale mineralization in South China,we deployed a 350-km-long,wide-angle seismic reflection/refraction sounding profile between Yingshan in Hubei and Changshan in Zhejiang.This profile traverses the Cu-Au metallogenic belt in the middle and lower reaches of the Yangtze River(YMB),the Jiangnan W-polymetal metallogenic belt(JNMB),and the Qinhang Cu-polymetal metallogenic belt(QHMB).Our imaging results reveal various interesting velocity features along the profile.(1)The velocity structure is characterized by vertical layering and horizontal blocking;(2)the YMB is marked by high velocity and high V_(p)/V_(s) ratios in general with a significantly uplifted Moho interface and a thin crust of~31 km,and the lower crust contains high-velocity anomalies and has the characteristics of a crustmantle transition zone;(3)the JNMB is bounded by the Jiangnan fault and Jingdezhen-Huangshan fault and has low-velocity anomalies and low V_(p)/V_(s) ratios;and(4)the QHMB is characterized by high-velocity anomalies and high V_(p)/V_(s) ratios.The highvelocity anomalies in the YMB and QHMB represent relatively Cu-Au-rich mafic juvenile lower crust.The formation of this kind of crust is considered to be related to mantle-derived magma underplating or residues of Neoproterozoic oceanic crustal materials,and it also provided sources for large-scale Cu-Au mineralization in the Mesozoic.The JNMB has features similar to those of ancient crusts enriched in W-Sn,the partial melting of which played a leading role in the formation of the superlarge W deposits in this belt.Considering these results and other regional geological data,we propose that a large-scale oblique upwelling of the asthenosphere along the collisional belt of the Yangtze and Cathaysia blocks during the Mesozoic was the deep driving mechanism for the explosive mineralization of Cu,Au,and W in northeastern South China.The boundaries of the blocks or terrains and discontinuities of the lithosphere were the main channels for deep heat and magmas and therefore controlled the spatial distribution of the metallogenic belt. | Jue HOU Tao XU Qingtian LV Zhiming BAI Yongqian ZHANG Zhiyu ZHANG Dan YANG | 2022 | Science China Earth Sciences2022，65，11： | 0 |
| 17 | Trade-offs between ion-conducting and mechanical properties: The case of polyacrylate electrolytes显示文摘Polymer electrolytes(PEs)have been long recognized as the key materials to enable energy-dense batteries and render flexible energy devices practically viable,owing to their chemical and mechanical reliability.However,much of their promise is yet to be realized.The roomtemperature ion conductivity of existing PEs still falls short of the implementation criterion of 10^(-4) S cm^(-1) on the promise of acceptable mechanical properties,thereby precluding their practical application.The twin but inversely related duties of polymers,that is,functioning as both an ion-conducting medium and a structural backbone,underlie this issue but are less elucidated systematically.The polyacrylate(PA)family is among promising polymer matrices on account of ester polarity,electrode compatibility,chemical tunability,and mechanical durability.The extensive applicability of PA in plasticized gels,dry solids,and emerging composites makes PA-based PEs representative to illustrate the trade-off between ion conduction and mechanical strength.We herein seek to outline the stated long-standing conflict exemplified by PA-based PEs,focusing on crucial strategies toward balancing and reconciling the two mutually exclusive properties,with the intention of offering designing guidelines for next-generation PEs. | Guoli Lu Yaojian Zhang Jianjun Zhang Xiaofan Du Zhaolin Lv Junzhe Du Zhiming Zhao Yue Tang Jingwen Zhao Guanglei Cui | 2023 | Carbon Energy2023，5，2： | 0 |
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