|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 基于状态图的对象行为建模显示文摘状态图(State Chart)是对对象的行为的一种描述的方法,并是UML(Unified ModelingLanguage)可视化建模的一部分.文中分析了状态图建模的规则,以及如何用状态图对对象的行为进行建模的方法. | 刘忠 邓苏 沙基昌 张维明 LIU Zhong DENG Su Sha Jichang ZHANG Weiming | 2001 | 计算机工程与设计2001，22，2： | 9 |
| 2 | Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)显示文摘Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African countries.To reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries.The major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and watermelon.Comparative analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter gourd.Phylogenetic analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from M.charantia.Furthermore,we found that the remaining 166 M.charantia germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,respectively.This study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd. | Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu | 2020 | Horticulture Research2020，7，1： | 7 |
| 3 | Applying XML for designing and interchanging information for multidimensional model显示文摘In order to exchange and share information among the conceptual models of data warehouse, and to build a solid base for the integration and share of metadata, a new multidimensional concept model is presented based on XML and its DTD is defined, which can perfectly describe various semantic characteristics of multidimensional conceptual model. According to the multidimensional conceptual modeling technique which is based on UML, the mapping algorithm between the multidimensional conceptual model is described based on XML and UML class diagram, and an application base for the wide use of this technique is given. | Lu Changhui Deng Su Zhang Weiming | 2005 | Journal of Systems Engineering and Electronics2005，16，4： | 2 |
| 4 | Experimental Studies on Impulse Flashover Characteristics of Tower Head Air Gaps of±1 000 kV DC Transmission Lines and显示文摘 | DING Yujian LIAO Weiming SUN Zhaoying SU Zhiyi | 2011 | 中国电机工程学报2011，31，34： | 1 |
| 5 | One-step synthesis of hierarchically porous hybrid TiO2 hollow spheres with high photocatalytic activity显示文摘 | Ruiping LIU Feng REN Jinlin YANG Weiming SU Zhiming SUN Lei ZHANG Chang-an WANG | 2016 | Frontiers of Materials Science2016，10，1： | 1 |
| 6 | Transgenic tomato overexpressing ath-miR399d has enhanced phosphorus accumulation through increased acid phosphatase and proton secretion as well as phosphate transporters显示文摘 | Nan Gao Yanhua Su Ju Min Weishou Shen Weiming Shi | 2010 | Plant and Soil (-)2010，，1： | 1 |
| 7 | The develop- ment of random signal radars显示文摘 | LIU Guosui GU Hong SU Weiming | 1999 | IEEE Transactions on Aerospace and Electronic Systems1999，35，3： | 1 |
| 8 | EXISTENCE OF MULTIPLE PERIODIC SOLUTIONS TO A SECOND-ORDER NONLINEAR DIFFERENCE SYSTEM显示文摘In this paper, by the critical point theory, a sufficient condition for the existence of multiple periodic solutions to a nonlinear second order difference system is obtained. An illustrative example is given. Our results improve and generalize some known ones. | Weiming Tan, Fang Su , Xuewen Qin (Institute of Math. and Physics, Wuzhou University, Wuzhou 543002, Guangxi) | 2011 | Annals of Differential Equations2011，27，2： | 1 |
| 9 | Research on the discrimination methods of algae based on the fluorescence excitation spectra显示文摘The excitation spectra of chlorophyll (Chl) fluorescence can be used to differentiate phytoplankton populations at phylum level in vivo and in situ within a few minutes.The investigated phytoplankton divisions (Dinophyta,Bacillariophyta,Chrysophyta,Cyanophyta,Cryptophyta,Chlorophyta) are each characterized by a specific composition of photosynthetic antenna pigments and,consequently,by a specific excitation spectrum of the Chl fluorescence.Norm excitation spectra (emission of 680 nm and excitation of 400–600 nm) of every division were obtained from several species per division by a F4500 fluorescence spectrophotometer.Fisher’s linear discriminant analysis of the norm spectra shows that the divisions could be discriminated.The discrimination method,established by multivariate linear regression and weighted least squares,was used to differentiate the phytoplankton samples cultured in the laboratory and samples collected from the Jiaozhao Bay at division level.The correctly discriminated samples were more than 94% for single algal species ones,more than 84% for simulatively mixed ones,more than 83% for real mixed ones and 100% for samples collected from the Jiaozhou Bay for the dominant species.The method for phytoplankton differentiation described here can be applied to routine checking by fluorescence spectrophotometer,and benefit the monitoring and supervision tasks related to phytoplankton populations in the marine environments. | HU Xupeng SU Rongguo ZOU Weiming REN Shijun WANG Hongtao CHAI Xiaoping WANG Yiming | 2010 | Acta Oceanologica Sinica2010，29，4： | 1 |
| 10 | The develop- ment of random signal radars显示文摘 | LIU Guosui GU Hong Su Weiming | 1999 | IEEE Transactions on Aerospace and Electronic Systems1999，35，3： | 1 |
| 11 | Use of hydrous manganese dioxide as a potential sorbent for selective removal of lead, cadmium, and zinc ions from water显示文摘 | Qin Su Bingcai Pan Shunli Wan Weiming Zhang Lu Lv | 2010 | Journal of Colloid And Interface Science2010，，2： | 1 |
| 12 | Functions and Design Scheme of Tibet High Altitude Test Base显示文摘The functional orientation of the Tibet High Altitude Test Base, subordinated to the State Grid Corporation of China (SGCC), is to serve power transmission projects in high altitude areas, especially to provide technical support for southwestern hydropower delivery projects by UHVDC transmission and Qinghai-Tibet grid interconnection project. This paper presents the matters concerned during siting and planning, functions, design scheme, the main performances and parameters of the test facilities, as well as the tests and research tasks already carried out. | Yu Yongqing, Li Guangfan, Fan Jianbin, Lu Jiayu, Su Zhiyi, Li Peng, Li Qingfeng, Liao Weiming, Zhou Jun, Guo Jian, Yin Yu and Mao Yan China Electric Power Research Institute Li Peng | 2010 | Electricity2010，21，2： | 0 |
| 13 | Complement of ^(99m)Tc-octreotide scintimammography to mammography in evaluating breast cancers显示文摘In this paper,the 99mTc-octreotide scintimammography as a useful complementary technique of mammography was evaluated in diagnosing breast cancers.The 45 breast lesions were consecutively detected by mammography,and 99mTc-octreotide scintimammography,and both combination technique on the basis of self-examination,physical examination.Clinical diagnosis was confirmed by histopathologic analysis.Radioactivity uptake ratios for tumor vs normal breast tissues (T/NT) were calculated using regions of interest.In the breast cancer groups and the benign lesion groups,the average uptake ratios of the 99mTc-octreotide were 1.63±0.19 and 1.09±0.13,respectively,and t was 9.638 (P<0.001).Based on sensitivity,specificity,accuracy,positive predicting value,and negative predicting value,99mTc-octreotide scintimammography was 87%,79%,84%,90%,and 73%,the mammography was 65%,64%,64%,80%,and 45%,and both combination was 95%,100%,97%,100% and 92%,respectively.This showed that the 99mTc-octreotide scintimammography was more useful than mammography in the evaluating suspected breast cancers,and the combination technique can accurately discriminate lesions. | SU Xinhui HE Xiaojiang WU Hua PAN Weiming HUANG Jingxiong YU Hao CHEN Guibing WANG Wei | 2010 | Nuclear Science and Techniques2010，21，1： | 0 |
| 14 | Organization Mission Planning: Methodology and Application显示文摘Mission planning of organization is to select best strategy to complete its mission under the conditions of organizational states. A new methodology of generating and optimizing strategy of organizational course of actions (COA) was illuminated with a joint campaign. A process of generating and optimizing COA in military force was modeled. And enumerative and heuristic techniques were employed to search optimal strategy for the case of joint campaign. The complex between the two approaches to find best strategy was analyzed. The results from our case were given and compared with reality of joint campaign, on which deficiency of models was taken apart. The optimal COA, obtained from our new methodology under diverse campaigns conditions, is given and analyzed. Results from the simulation of the COA show that our approach to solve optimal strategy of organizational processes accords with traits of general landing campaign. | YANG Dongsheng LIU Zhong ZHANG Weiming SU Ping | 2005 | Tsinghua Science and Technology2005，10，z1： | 0 |
| 15 | ZBTB7A governs 2-DG-inhibited glycolysis by regulating GLUT1 in nasopharyngeal carcinoma显示文摘Our previous studies suggested a potential interaction between the POK erythroid myeloid ontogenic factor ZBTB7A and glucose transporter 1(GLUT1)in nasopharyngeal carcinoma(NPC).This study was designed to confirm the interaction and further evaluate the precise mechanism by which ZBTB7A and GLUT1 regulate NPC development.The binding sites between ZBTB7A and the promoter of GLUT1 were predicted by bioinformatics.Gene expression was measured by quantitative real-time polymerase chain reaction(qPCR),western blotting,and immunohistochemistry.The activities of key glycolysis enzymes,including hexokinase(HK),pyruvate kinase(PK),lactate dehydrogenase(LDH),and lactate,were detected using specific enzyme-linked immunosorbent assay kits.The connection between ZBTB7A and GLUT1 was analyzed by dual-luciferase reporter assay and chromatin immunoprecipitation-qPCR.The vitality,proliferation,and tumorigenicity of the cells expressing different levels of ZBTB7A were tested by adding the glycolysis inhibitor 2-deoxy-D-glucose(2-DG),followed by MTT,colorimetric focus forming,and xenograft assays,respectively.Our results showed that high expression of GLUT1 was associated with late-stage NPC.After constructing stably transfected cells with lentiviruses,ZBTB7A was effectively knocked down in 5-8F cells(RNAi-5-8F)and overexpressed in 6-10B cells(ZBTB7A-6-10B).The up-or downregulation of GLUT1 secondary to ZBTB7A changes was also limited.The vitality and proliferation of the cells expressing low ZBTB7A were notably blocked by 2-DG.The cells expressing high ZBTB7A were not very sensitive to 2-DG.The growth of RNAi-5-8F xenografts was strongly suppressed by 2-DG.The activities of HK,PK,and LDH were suppressed by 2-DG in the cells expressing low ZBTB7A.RNAi-5-8F cells had the lowest 2-DG-induced lactate production.ZBTB7A directly suppressed the promoter region of GLUT1 to regulate GLUT1 expression.Thus,ZBTB7A controls the 2-DG-induced inhibition of glycolysis by affecting GLUT1. | FEI LIU JIAZHANG WEI JIAO LAN YONGLI WANG JIANXIANG YE CHENG SU MINGZHENG MO FENGZHU TANG BING LI MIN LI WEIMING DENG LINSONG YE WENLIN HUANG JINGJIN WENG WEI JIAO SHENHONG QU | 2022 | BIOCELL2022，46，12： | 0 |
| 16 | Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease显示文摘Background and Aims:Osteopontin(OPN)is reported to be associated with the pathogenesis of nonalcoholic fatty liver disease(NAFLD).However,the function of OPN in NAFLD is still inconclusive.Therefore,our aim in this study was to evaluate the role of OPN in NAFLD and clarify the involved mechanisms.Methods:We analyzed the expression change of OPN in NAFLD by bioinformatic analysis,qRT-PCR,western blotting and immunofluorescence staining.To clarify the role of OPN in NAFLD,the effect of OPN from HepG2 cells on macrophage polarization and the involved mechanisms were examined by FACS and western blotting.Results:OPN was significantly upregulated in NAFLD patients compared with normal volunteers by microarray data,and the high expression of OPN was related with disease stage and progression.OPN level was also significantly increased in liver tissue samples of NAFLD from human and mouse,and in HepG2 cells treated with oleic acid(OA).Furthermore,the supernatants of OPN-treated HepG2 cells promoted the macrophage M1 polarization.Mechanistically,OPN activated the janus kinase 1(JAK1)/signal transducers and activators of transcription 1(STAT1)signaling pathway in HepG2 cells,and consequently HepG2 cells secreted more high-mobility group box 1(HMGB1),thereby promoting macrophage M1 polarization.Conclusions:OPN promoted macrophage M1 polarization by increasing JAK1/STAT1-induced HMGB1 secretion in hepatocytes. | Zhihao Xu Feiyang Xi Xinxin Deng Yuqi Ni Changqin Pu Dan Wang Weiming Lou Xufang Zeng Ning Su Chen Chen Ziqiang Zeng Libin Deng Meixiu Jiang | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员