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| 1 | Enhanced tolerance to drought stress in transgenic tobacco plants overexpressing VTE1 for increased tocopherol production from Arabidopsis thaliana显示文摘 | Xiaoli Liu Xuejun Hua Juan Guo Dongmei Qi Lijuan Wang Zhipeng Liu Zhiping Jin Shuangyan Chen Gongshe Liu | 2008 | Biotechnology Letters2008，，7： | 1 |
| 2 | Enhanced drought tolerance in transgenic Leymus?chinensis plants with constitutively expressed wheat TaLEA 3显示文摘 | Lijuan Wang Xiaofeng Li Shuangyan Chen Gongshe Liu | 2009 | Biotechnology Letters2009，，2： | 1 |
| 3 | Crustins from eyestalk cDNA library of swimming crab Portunus trituberculatus : Molecular characterization, genomic organization and expression analysis显示文摘 | Zhaoxia Cui Chengwen Song Yuan Liu Shuangyan Wang Qianqian Li Xihong Li | 2012 | Fish and Shellfish Immunology2012，，4： | 1 |
| 4 | Enhanced drought tolerance in transgenic Leymus?chinensis plants with constitutively expressed wheat TaLEA 3显示文摘 | Lijuan Wang Xiaofeng Li Shuangyan Chen Gongshe Liu | 2009 | Biotechnology Letters2009，，2： | 1 |
| 5 | The ability of NT-proBNP to detect chronic heart failure and predict all-cause mortality is higher in elderly Chinese coronary artery disease patients with chronic kidney disease显示文摘 | Shihui Fu Ying Ye Yongyi Bai Tiehui Xiao Liang Wang Bing Zhu Yuan Liu Shuangyan Yi Leiming Luo | 2013 | 2013 (defa)2013，，： | 1 |
| 6 | Crustins from eyestalk cDNA library of swimming crab Portunus trituberculatus : Molecular characterization, genomic organization and expression analysis显示文摘 | Zhaoxia Cui Chengwen Song Yuan Liu Shuangyan Wang Qianqian Li Xihong Li | 2012 | Fish and Shellfish Immunology2012，，4： | 1 |
| 7 | Relationship of recurrent laryngeal nerve with inferior horn of thyroid cartilage,inferior thyroid artery,berry's ligament and Zuckerkandl's tubercle:A study in corpses显示文摘The pivotal role of four anatomical landmarks:inferior horn of thyroid cartilage,inferior thyroid artery(ITA),Berry's ligament(BL)and Zuckerkandl's tubercle(ZT)on recurrent laryngeal nerve(RLN)protection has received more attention.In our study,anatomy of 14 specimens(28 sides in total)were dissected to investigate the relationship between RLN and these four landmarks. | Wang Changjing Xia Yujun Wang Shuangyan | 2021 | 解剖学杂志2021，44，S01： | 1 |
| 8 | Exploration of Near Water Rural Landscape Planning and Design:Taking Shiping Village,Zhijiang City in Hubei Province as an Example显示文摘By centering on the problems in rural environment and ecology in new rural planning of China,this study is to discuss the new rural planning modes through the effective methods on the near water rural landscape planning and design.Based on the studies of the status at home and abroad,borrowing ideas from successful cases,this study intends to apply the landscape ecological design technique to the Shiping Village,Zhijiang City in Hubei Province by depending on the near water geographical position and water resources.Through improving pools,fishponds,rivers,canals and other environments near water and planning and design of landscape,modern ecological new countryside with features of water resource is formed.Through discussion,we find effective ways to improve ecological environment of countryside,protect style and feature of countryside near water,construct people-oriented rural development system of and promote the construction of rural human habitat environment.Such landscape planning model of countryside near water obtains good ecological and environmental effect,and provides references for projects of similar themes. | WANG Hongying SUN Shuangyan MA Lingyun | 2012 | Journal of Landscape Research2012，4，11： | 1 |
| 9 | Restoration of Eutrophic Water Using Nymphaea tetragona Georgi显示文摘[Objective]The study aimed to explore the approaches of utilizing Nymphaea tetragona Georgi by doing research on removing nitrogen and phosphorus from sewage using N.tetragona Georgi.[Method]With N.tetragona Georgi as the research object,a comparative analysis on the content of total nitrogen(TN) and total phosphorus(TP) was carried out after N.tetragona Georgi was planted in sewage.TN content was determined by alkaline potassium persulfate digestion-UV spectrophotometric method(GB11894-89),and TP content was measured by using ammonium molybdate spectrophotometric method(GB11893-89).[Result]The removal rate of TN and TP reached 12.31% and 8.64% respectively under natural conditions after N.tetragona Georgi was cultivate in the sewage for 13 days.Afterward,the removal rate has no significant change.[Conclusion]N.tetragona Georgi can purify sewage to some degree,and the removal efficiency of TN was higher than that of TP. | Xianxiang Dai Dongli Duan Shuangyan Wang Zumin Zhang Zhouping Yang Hua Zhen | 2013 | Meteorological and Environmental Research2013，4，1： | 1 |
| 10 | The effect of geometric layout of exit on escape mechanism of crowd显示文摘In dense crowd evacuation,especially in emergencies such as fires,the safe evacuation of large public facilities will face major challenges.At the same time,as cluster congestion tends to occur in the space where the flow rate drops sharply,the superposition of fire incidents and bottleneck areas can easily evolve into malignant disasters and crowd stampedes with serious harm and influence.In this paper,Massmotion based on social force model is used to carry out a numerical simulation on exit position and corner exit form to find out the mechanism and influence law of the slight architectural adjustment on the flow at bottleneck.The results show that the traditional middle exit design is not the best,and the evacuation efficiency of the corner exit is higher than that of the middle exit.Compared with other corner exits,the average time interval between two adjacent persons passing through the bottleneck under the 30°corner exit is the shortest,and the probability of outlet clogging drops the fastest,exceeding 18%of the slowest descending speed.At the 0°corner exit,the waiting time cost of pedestrians is high and the risk of evacuation is high.The outcomes of this work can provide reference for the structural design of the building and the safe evacuation of personnel,so as to improve the evacuation efficiency and safety of pedestrians in the building to some extent. | Jia Li Jinghong Wang Shuangyan Xu Jiaojiao Feng Jiachen Li Zhirong Wang Yan Wang | 2022 | Building Simulation2022，15，4： | 1 |
| 11 | Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure显示文摘Peritoneal fibrosis together with increased capillaries is the primary cause of peritoneal dialysis failure.Mesothelial cell loss is an initiating event for peritoneal fibrosis.We find that the elevated glucose concentrations in peritoneal dialysate drive mesothelial cell pyroptosis in a manner dependent on caspase-3 and Gasdermin E,driving downstream inflammatory responses,including the activation of macrophages.Moreover,pyroptosis is associated with elevated vascular endothelial growth factor A and C,two key factors in vascular angiogenesis and lymphatic vessel formation.GSDME deficiency mice are protected from high glucose induced peritoneal fibrosis and ultrafiltration failure.Application of melatonin abrogates mesothelial cell pyroptosis through a MT1R-mediated action,and successfully reduces peritoneal fibrosis and angiogenesis in an animal model while preserving dialysis efficacy.Mechanistically,melatonin treatment maintains mitochondrial integrity in mesothelial cells,meanwhile activating m TOR signaling through an increase in the glycolysis product dihydroxyacetone phosphate.These effects together with quenching free radicals by melatonin help mesothelial cells maintain a relatively stable internal environment in the face of high-glucose stress.Thus,Melatonin treatment holds some promise in preserving mesothelium integrity and in decreasing angiogenesis to protect peritoneum function in patients undergoing peritoneal dialysis. | Hongxia Ruan Xuejuan Li Lina Zhou Zihan Zheng Rulin Hua Xu Wang Yuan Wang Yujie Fan Shuwen Guo Lihua Wang Shafiq ur Rahman Ziwei Wang Yuyuan Wei Shuangyan Yu Rongzhi Zhang Qian Cheng Jie Sheng Xue Li Xiaoyan Liu Ruqiang Yuan Xiaoyan Zhang Lihong Chen Guowang Xu Youfei Guan Jing Nie Hongqiang Qin Feng Zheng | 2024 | Science China(Life Sciences)2024，67，2： | 0 |
| 12 | Preliminary Study on Heavy Metal Pollution Status of Farmland Soil at Two Sides of Cheng-Guan Expressway显示文摘The heavy metal content of the farmland soil at two sides of Cheng-Guan Expressway is measured to make a preliminary evaluation on its heavy metal pollution status.After digestion and volume fixation of the soil samples collected,measure the Cu,Zn,Cd,Pb and Cr content with atomic absorption spectrophotometry and evaluate the measured data according to Level Two of National Soil Environmental Quality Standard to obtain the contamination status.Cu,Zn and Cd content of the farmland soil for sections of Cheng-Guan Expressway goes beyond Level Two of National Soil Environmental Quality Standard,while the Pb and Cr content meets Level Two of National Soil Environmental Quality Standard.Pb and Cr content of the farmland soil at two sides of Cheng-Guan Expressway is in safe state,while the Cu,Zn and Cd content is in a mild contamination state.Cu,Zn and Cd are the main pollution elements. | Dongli DUAN Shuangyan WANG Zumin ZHANG Zhouping YANG Hua ZHEN | 2013 | Asian Agricultural Research2013，5，8： | 0 |
| 13 | Research advances in peptide-drug conjugates显示文摘Peptide-drug conjugates(PDCs)are drug delivery systems consisting of a drug covalently coupled to a multifunctional peptide via a cleavable linker.As an emerging prodrug strategy,PDCs not only preserve the function and bioactivity of the peptides but also release the drugs responsively with the cleavable property of the linkers.Given the ability to significantly improve the circulation stability and targeting of drugs in vivo and reduce the toxic side effects of drugs,PDCs have already been extensively applied in drug delivery.Herein,we review the types and mechanisms of peptides,linkers and drugs used to construct PDCs,and summarize the clinical applications and challenges of PDC drugs. | Liming Gong Heming Zhao Yanhong Liu Hao Wu Chao Liu Shuangyan Chang Liqing Chen Mingji Jin Qiming Wang Zhonggao Gao Wei Huang | 2023 | Acta Pharmaceutica Sinica B2023，13，9： | 0 |
| 14 | Manganese-Fluorouracil Metallodrug Nanotheranostic for MRI-Correlated Drug Release and Enhanced Chemoradiotherapy显示文摘For cancer therapy,drug delivery systems are often limited by insufficient drug loading capacity,which usually results in systemic toxicity and heavy metabolic burden to excrete the carriers.Herein,we reported a“one-pot”method for constructing metal(Mn^(2+))–fluorouracil(FU)-coordinated nanotheranostics(Mn-FU)by self-assembly of FU(as bridging ligands)and Mn^(2+)(as metal nodes)through Mn–N/O coordination interactions.Importantly,owing to the effective coordination between Mn and FU,Mn-FU exhibits high drug loading efficacy(47.7 wt%),encapsulation efficacy(82.6%),and relatively large yield(1 g/pot).In acidic tumor microenvironments,efficient release of FU and Mn^(2+)is realized because of nitrogen protonation.The released FU and Mn^(2+)from Mn-FU are used for chemotherapy and turn on magnetic resonance imaging(MRI),respectively,achieving MRI-correlated drug release.After PEG modification,Mn-FU displays high tumor homing ability via enhanced permeability and retention effects and quick renal clearance owing to the disassembly in acidic biological conditions.As a result,Mn-FU substantially enhances the synergistic effects of chemoradiotherapy.Meanwhile,the systemic toxic side effects of free FU-based chemoradiotherapy were greatly reduced through this nanotheranostic.Our strategy offers a facile way to construct metallodrug nanotheranostics for efficient cancer theranostics. | Chan Yang Guosheng Song Haifeng Yuan Yue Yang Yuqi Wang Deju Ye Hongmin Meng Shuangyan Huan Xiao-Bing Zhang | 2021 | CCS Chemistry2021，3，4： | 0 |
| 15 | Tone of language,financial disclosure,and earnings management:a textual analysis of form 20-F显示文摘This study investigates the relationship between the tone of financial disclosures and managers’earnings management behavior using Form 20-F filings of Chinese firms listed in the U.S.during 2002–2014.The results show that the proportion of positive,uncertain,or modal words used in financial disclosures is positively related to corporate earnings management,implying that managers attempt to conceal earnings management behavior by manipulating the tone of their financial reports.In addition,robustness tests are conducted using an alternative proxy for earnings management that considers the effects of the financial crisis and separately examines the information and non-information technology industries.The results suggest that the tone used in financial disclosures has informative value,and textual analysis can be an effective tool for identifying earnings management. | Shuangyan Li Guangrui Wang Yongli Luo | 2022 | Financial Innovation2022，8，1： | 0 |
| 16 | Mechanical Analysis and Optimal Design on Transfer Case显示文摘Transfer case of all-terrain vehicle is classic cylindrical helical gear rotor system for power transmission.The power of motor is distributed to the driving axles through it.The mechanical model is established to study its performance and the data is applied to design the structure. | WANG Xinbo ZHU Xuebin LIU Shuangyan WANG Di AN Guangle SONG Xiaobo | 2021 | International Journal of Plant Engineering and Management2021，26，1： | 0 |
| 17 | SnTe nanoparticles physicochemically encapsulated by double carbon as conversion-alloying anode materials for superior potassium-ion batteries显示文摘Telluride tin(SnTe)is a promising conversion-alloying anode for potassium-ion batteries(PIBs)due to its high theoretical specific capacity induced by multi-electron transport reaction and low operating voltage,whereas huge volume expansion and poor kinetics behavior become key scientific bottleneck limiting the battery performances.Herein,SnTe nanoparticles physicochemically wrapped by graphene and nitrogen-doped carbon(SnTe@rGO@NC)are proposed as anode materials for PIBs.The pre-electrostatic interaction urges the formation of Sn-C and Te-C chemical bonds between SnTe and double carbon to strengthen the interfacial stability and electron transfer,and the conductive architecture with hierarchical encapsulation effect is beneficial to maintaining the electrode integrity and electrochemical dynamics.It is demon-strated from first principles calculations and experimental results that SnTe@rGO@NC contributes fast electron transmission,strong K-ion adsorption,and superior K-ion diffusion capability.Ex-situ characteri-zations uncover that SnTe undergoes conversion-alloying dual-mechanism with the products of K_(2)Te and K_(4)Sn_(23)replied on Sn redox site(23SnTe+50K^(+)+50e^(-)↔K_(4)Sn_(23)+23K_(2)Te).Thus,the SnTe@rGO@NC electrode delivers a high initial charge specific capacity of 243.9 mAh g^(-1)at 50 mA g^(-1),superior rate performance(112.6 mAh g^(-1)at 1.0 A g^(-1)),and outstanding cyclic stability at various current densities. | Ting Li Yikun Wang Qianwen Zhou Lingling Yuan Shuangyan Qiao Meng Ma Zhengqing Liu Shaokun Chong | 2023 | Journal of Materials Science & Technology2023，，27： | 0 |
| 18 | Characterization of Carboxymethyl Cellulose Made from Bamboo Harvesting Residues显示文摘Bamboo harvesting residues are wastes by-products of bamboo industries that contain holocellulose for about 63.14%to 70.71%,which often be discarded,incinerated or buried.In this study,carboxymethyl cellulose was prepared from bamboo harvesting residues(bamboo-branch and bamboo-tip)as raw materials.The chemical composition of bamboo harvesting residues,the viscosity and degree of substitution of carboxymethyl cellulose were determined.Carboxymethyl cellulose obtained was further characterized and compared by means of FTIR,SEM,XRD and TG.Results showed that under the optimized identical conditions,the viscosity and degree of substitution of carboxymethyl cellulose from bamboo-branch and bamboo-tip were 6.0 and 78.9 mPa·s,0.75 and 0.89,respectively.Carboxymethyl cellulose obtained from bamboo-tip displayed a lower crystallinity and a better thermal stability as compared to synthetic carboxymethyl cellulose obtained from bamboo-branch and bamboo-culm. | Shuangyan Zhang Shun Yang Chuangui Wang Weiyi Su Huangfei Lv Yuanyuan Li | 2022 | Journal of Renewable Materials2022，10，12： | 0 |
| 19 | Adsorption equilibria of paeoniflorin and albiflorin on cyano-silica column from supercritical carbon dioxide/ethanol显示文摘Adsorption equilibria of paeoniflorin and albiflorin on a cyano-silica column(CN column) from the solution of supercritical carbon dioxide(scCO2) modified with ethanol were studied. The adsorption capacity at 308.15 K,313.15 K, 318.15 K and 323.15 K under pressures corresponding to carbon dioxide/ethanol densities from0.347 g·cm^-3 to 0.662 g·cm^-3 were determined using the elution by characteristic point method(ECP). The effects of temperature and pressure on the solute loading were investigated. The results showed that the lower the temperature, the higher the adsorption capacity. With the decrease of density of scCO2, the adsorption capacity strengthens. The maximum adsorption capacity of paeoniflorin(albiflorin) on the CN column was15.24 mg·ml^-1(31.14 mg·ml^-1) in the range of 0–1.84 mg·ml^-1(0–1.67 mg·ml^-1) of paeoniflorin(albiflorin)standard solution. The adsorption capacity of albiflorin was twice as much as that of paeoniflorin under the same conditions. Adsorption data of paeoniflorin and albiflorin could be well described by the Langmuir model and Freundlich model. Compared with the two model fitting results, the adsorption of paeoniflorin and albiflorin belonged to the monolayer adsorption under conditions of 308.15–323.15 K and 10–17 MPa. | Huisheng Lü Zhi Wang Zhongfeng Geng Yonghui Li Shuangyan Liu Jiatao Liu | 2019 | Chinese Journal of Chemical Engineering2019，27，4： | 0 |
| 20 | A controllable self-localized imaging strategy capable of synchronous in situ tracking of local changes in intracellular bioactive small-molecules显示文摘In situ tracking and localization of ubiquitous bioactive small molecules(BSMs)within their native habitats is particularly challenging because of their low-molecular weight and widespread distribution properties.We report the proof of concept of a synchronous in situ imaging strategy,whereby the representative BSM amino-biothiols(ABs)mediate activation of the selflocalizable probe HYPQS,thereby releasing insoluble emissive precipitates to afford holistic distribution information of ABs.Notably,three organelle-targetable ABs inhibitors were innovatively fabricated for directed clearance of ABs in particular organelles,providing a powerful aid for HYPQS to achieve programmed in situ tracking of ABs in different organelles“on demand”.Biological transmission electron microscopy images confirmed that this probe released insoluble emissive precipitates at the reaction sites,which is of primary importance for achieving synchronous in situ tracking of BSMs.Furthermore,the probe HYPQS was successfully applied to monitor the dynamic changes in the endogenous ABs pool during diverse cell events.This strategy opens a promising avenue for investigating the undiscovered functional mechanism of local BSMs in relevant biological processes. | Ke Li Shuai Xu Benhua Wang Shuangyan Huan Xiangzhi Song Lin Yuan Xiao-Bing Zhang | 2023 | Science China Chemistry2023，66，8： | 0 |
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