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| 1 | Optical meta-waveguides for integrated photonics and beyond显示文摘The growing maturity of nanofabrication has ushered massive sophisticated optical structures available on a photonic chip.The integration of subwavelength-structured metasurfaces and metamaterials on the canonical building block of optical waveguides is gradually reshaping the landscape of photonic integrated circuits,giving rise to numerous metawaveguides with unprecedented strength in controlling guided electromagnetic waves.Here,we review recent advances in meta-structured waveguides that synergize various functional subwavelength photonic architectures with diverse waveguide platforms,such as dielectric or plasmonic waveguides and optical fibers.Foundational results and representative applications are comprehensively summarized.Brief physical models with explicit design tutorials,either physical intuition-based design methods or computer algorithms-based inverse designs,are cataloged as well.We highlight how meta-optics can infuse new degrees of freedom to waveguide-based devices and systems,by enhancing light-matter interaction strength to drastically boost device performance,or offering a versatile designer media for manipulating light in nanoscale to enable novel functionalities.We further discuss current challenges and outline emerging opportunities of this vibrant field for various applications in photonic integrated circuits,biomedical sensing,artificial intelligence and beyond. | Yuan Meng Yizhen Chen Longhui Lu Yimin Ding Andrea Cusano Jonathan A.Fan Qiaomu Hu Kaiyuan Wang Zhenwei Xie Zhoutian Liu Yuanmu Yang Qiang Liu Mali Gong Qirong Xiao Shulin Sun Minming Zhang Xiaocong Yuan Xingjie Ni | 2021 | Light(Science & Applications)2021，10，12： | 6 |
| 2 | Surface Amendments Can Ameliorate Subsoil Acidity in Tea Garden Soils of High-Rainfall Environments显示文摘强烈酸的土壤(pH < 5.0 ) 对茶(山茶 sinensis ) 有害生产和质量。很少信息都不在表面修正案的能力上存在改善在茶花园土壤的心土酸味。A 120-d 温室列沥滤实验用通常可得到的土壤改良物被进行。碱的炉渣(作为) 并且器官的残余,猪粪肥(下午) 和在灰碱度和 C/N 比率不同的油菜籽蛋糕(RC ) 独自并且在联合被合并到土壤列的表面(0-15 厘米)(10 厘米内部的直径 ×
50 厘米长) 从 Ultisol 的酸的土壤层(15-30 厘米) 与土壤收拾行李(起始的 pH = 4.4 ) 。在 120-d 实验期间,土壤列被浇(在 9 应用上的大约 127 公里) 根据长期的平均数,年度降雨(1 143 公里) 和 leachates 镇定、分析。在实验的结束,土壤列被划分成各种各样的深度,土壤的化学性质被测量。有更高的 C/N 比率的下午增加了心土 pH,而有更低的 C/N 比率的 RC 减少了心土 pH。然而,联合了有的修正案独自修正案比也减少心土酸味的一个极有能力。心土的 pH 的增加主要被归功于到减少的基础阳离子集中和在溶解的器官的碳(文档) 和从修改的层被沥滤在下面的硝酸盐的固定在场的器官的阴离子的分解。一重要(P < 0.05 ) 在碱度生产之间的关联(减少的可交换的酸味 -N 周期碱度) 并且碱度平衡(网碱度生产 -N 周期碱度) 在实验的结束被观察。另外,联合了显著地增加的修正案(P < 0.05 ) 心土阳离子集中和减少的心土艾尔浸透(P < 0.05 ) 。联合应用就象表面的器官的修正案,土壤在在高降雨的区域减少心土酸味是有效的。在地条件下面并且在更长的 timeframes 上的进一步的调查被需要充分在改善理解他们的实际有效性在自然地发生沥滤下面的更深的土壤层的酸味政体。 | WANG Lei Clayton R. BUTTERLY CHEN Qiuhui MU Zhibo WANG Xia XI Yunguan ZHANG Jibing XIAO Xingji | 2016 | Pedosphere2016，26，2： | 5 |
| 3 | Strength and deformation behaviors of veined marble specimens after vacuum heat treatment under conventional triaxial compression显示文摘The mechanical behaviors of rocks affected by high temperature and stress are generally believed to be significant for the stability of certain projects involving rocks, such as nuclear waste storage and geothermal resource exploitation. In this paper, veined marble specimens were treated to high temperature treatment and then used in conventional triaxial compression tests to investigate the effect of temperature, confining pressure, and vein angle on strength and deformation behaviors. The results show that the strength and deformation parameters of the veined marble specimens changed with the temperature, presenting a critical temperature of 600℃. The triaxial compression strength of a horizontal vein(β = 90°) is obviously larger than that of a vertical vein(β = 0°). The triaxial compression strength,elasticity modulus, and secant modulus have an approximately linear relation to the confining pressure. Finally,Mohr–Coulomb and Hoek–Brown criteria were respectively used to analyze the effect of confining pressure on triaxial compression strength. | Haijian Su Hongwen Jing Qian Yin Liyuan Yu Yingchao Wang Xingjie Wu | 2017 | Acta Mechanica Sinica2017，33，5： | 5 |
| 4 | Enhancement for φ-OTDR Performance by Using Narrow Linewidth Light Source and Signal Processing显示文摘以便基于阶段敏感的光时间域反射计提高一个分布式的声学的察觉到系统的 signal-to-noise-ratio (我们建议了的 -OTDR), 分割的 unwrapping 算法,阶段差别的平均评价,和过滤方法的无限的推动反应(IIR ) 的联合。信号质量的改进数字地被表明。而且,我们学习了影响在 -OTDR 表演上源于轻来源噪音。结果看了那在 -OTDR 系统使用的轻来源的线宽什么时候更狭窄,系统的表演更好。简言之,当更狭窄的线宽光来源被选择,平均评价阶段差别的方法被使用时,如此的一个 -OTDR 系统能获得高质量的使解调的信号。 | Meng ZHANG Song WANG Yuanwei ZHENG Yao YANG Xingjie SA Li ZHANG | 2016 | Photonic Sensors2016，6，1： | 3 |
| 5 | Camptothecin-based nanodrug delivery systems显示文摘The drug camptothecin has a wide range of antitumor effects in cancers including gastric cancer,rectal and colon cancer,liver cancer,and lung cancer.Camptothecin-based drugs inhibit topoisomerase 1(Topo 1),leading to destruction of DNA,and are currently being used as important chemotherapeutic agents in clinical antitumor treatment.However,the main obstacle associated with cancer therapy is represented by systemic toxicity of conventional anticancer drugs and their low accumulation at the tumor site.In addition,low bioavailability,poor water solubility,and other shortcomings hinder their anticancer activity.Different from traditional pharmaceutical preparations,nanotechnology-dependent nanopharmaceutical preparations have become one of the main strategies for different countries worldwide to overcome drug development problems.In this review,we summarized the current hotspots and discussed a variety of camptothecin-based nanodrugs for cancer therapy.We hope that through this review,more efficient drug delivery systems could be designed with potential applications in clinical cancer therapy. | Yan Wen Yingze Wang Xiaoli Liu Wei Zhang Xinhe Xiong Zhongxiao Han Xingjie Liang | 2017 | Cancer Biology & Medicine2017，14，4： | 3 |
| 6 | Individual-tree diameter growth model for Korean pine plantations based on optimized interpolation of meteorological variables显示文摘To explore the influence of meteorological variables on the growth of Korean pine(Pinus koraiensis Sieb.et Zucc.) plantations and provide a scientific reference for the production and management of Korean pine,three approaches to interpolate meteorological variables during the growing season(i.e.,May-September) were compared in Heilongjiang Province,China.Optimized meteorological variable interpolation results were then combined with stand and individual tree variables,based on data from 56 sample plots and 2886 sample trees from Korean pine plantations in two regions of the province to develop an individualtree diameter growth model(Model I) and an individualtree diameter growth model with meteorological variables(Model Ⅱ) using a stepwise regression method.Moreover,an individual-tree diameter growth model with regional effects(Model Ⅲ) was developed using dummy variables in the regression,and the significance of introducing these dummy variables was verified with an F-test statistical analysis.The models were validated using an independent data set,and the predictive performance of the three models was assessed via the adjusted coefficient of determination(R_(a)^(2)) and root mean square error(RMSE).The results suggest that the growth increment in tree diameter of Korean pine plantations was significantly correlated with the natural logarithm of initial diameter(ln D),stand basal area(BAS),logarithmic deformation of the stand density index(ln SDI),ratio of basal area of trees larger than the subject tree to their initial diameter at breast height(DBH)(BAL/D),and the maximum growingseason precipitation(Pgmax).The individual-tree diameter growth models of Korean pine plantations developed in this study will provide a good basis for estimating and predicting growth increments of Korean pine forests over larger areas. | Man Wang Yinghui Zhao Zhen Zhen Xingji Jin | 2021 | Journal of Forestry Research2021，32，4： | 3 |
| 7 | Anti-NLRP3 inflammasome abietane diterpenoids from Callicarpa bodinieri and their structure elucidation显示文摘Callica rpabodinieri is a Chinese traditional medicine herb with anti-inflammatory activity in clinic.Herein,we report two new 9,10-seco and etherified abietane diterpenoids bodinieric acids J and K(1 and 2) and one known compound(3) isolated from the leaves and twigs of this plant.Their chemical structures were elucidated by detailed spectrometry data analysis and DP4+NMR calculation methods.Hypothetical biosynthetic pathways of 1-3 were preliminarily speculated.Compound 3 inhibited inflammasome activation and exhibited blockage of NLRP3 inflammasome activation at non-cytotoxic concentrations in vitro. | Junbo Gao Xingjie Zhang Kun Shang Weimao Zhong Ruihan Zhang Xiaochang Dai Xiaoli Li Qi Wang Yan Zou Weilie Xiao | 2020 | Chinese Chemical Letters2020，31，2： | 3 |
| 8 | A core-shell structured COYID-19 mRNA vaccine with favorable biodistribution pattern and promising immunity显示文摘Although inoculation of COVID-19 vaccines has rolled out globally,there is still a critical need for safe and effective vaccines to ensure fair and equitable supply for all countries.Here,we report on the development of a highly efficacious mRNA vaccine,SW0123 that is composed of sequence-modified mRNA encoding the full-length SARS-CoV-2 Spike protein packaged in core-shell structured lipopolyplex(LPP)nanoparticles.SWOT 23 is easy to produce using a large-scale microfluidics-based apparatus.The unique core-shell structured nanoparticle facilitates vaccine uptake and demonstrates a high colloidal stability,and a desirable biodistribution pattern with low liver targeting effect upon intramuscular administration.Extensive evaluations in mice and nonhuman primates revealed strong immunogenicity of SW0123,represented by induction of Th1-polarized T cell responses and high levels of antibodies that were capable of neutralizing not only the wild-type SARS-CoV-2,but also a panel of variants including D614G and N501Y variants.In addition,SW0123 conferred effective protection in both mice and non-human primates upon SARS-CoV-2 challenge.Taken together,SW0123 is a promising vaccine candidate that holds prospects for further evaluation in humans. | Ren Yang Yao Deng Baoying Huang Lei Huang Ang Lin Yuhua Li Wenling Wang Jingjing Liu Shuaiyao Lu Zhenzhen Zhan Yufei Wang Ruhan A Wen Wang Peihua Niu Li Zhao Shiqiang Li Xiaopin Ma Luyao Zhang Yujian Zhang Weiguo Yao Xingjie Liang Jincun Zhao Zhongmin Liu Xiaozhong Peng Hangwen Li Wenjie Tan | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 3 |
| 9 | Examination of Resource Curse Hypothesis: Mineral Resources Exploitation and Economic Growth in Xinjiang Autonomous Region显示文摘The mineral resources exploitation stage and the economic growth rate are various in different regions of Xinjiang Autonomous region. Using the method of location quotient, this paper identifies and classifies the intensive regions of three types of mineral resources, known as coal, oil and natural gas, respectively. The intensive regions of economic growth were also identified, according to the rate of per capita GDP growth at prefecture, autonomous prefecture and city. The relationships between different mineral resources and economic growth are different, for example, the relationship between economic growth and coal resource is positive, while the relationship between economic growth and oil resource, or natural gas resource is negative. This study empirically examines the effects of natural resources on economic growth of Xinjiang. The results show that whilst natural resources have a positive impact on growth, and can make a negative impact on growth through the transmission channels, such as investment, manufacture, human capital, and scientific and technologic innovation. Moreover, it studies the transmission channels, that is, the effect of natural resources on the other explanatory variables, and calculates the indirect effect of natural resources on growth for each transmission channel, and comprehensive effects of natural resources on growth. The calculated result of comprehensive effects indicates that the positive direct effects of natural resources on growth are shown to outweigh the negative indirect effect of Xinjiang autonomous region. | Zhang Xinhua Gu Shuzhong Wang Xingjie Wu Hong Zhou Hong Hu Yongjun | 2011 | Chinese Journal of Population,Resources and Environment2011，9，1： | 2 |
| 10 | A Toolkit of CRISPR-Based Genome Editing Systems in Drosophila显示文摘The last couple of years have witnessed an explosion in development of CRISPR-based genome editing technologies in cell lines as well as in model organisms. In this review, we focus on the applications of this popular system in Drosophila. We discuss the effectiveness of the CRISPR/Cas9 systems in terms of delivery, mutagenesis detection, parameters affecting efficiency, and off-target issues, with an emphasis on how to apply this powerful tool to characterize gene functions. | Jiang Xu Xingjie Ren Jin Sun Xia Wang Huan-Huan Qiao Bo-Wen Xu Lu-Ping Liu Jian-Quan Ni | 2015 | Journal of Genetics and Genomics2015，42，4： | 2 |
| 11 | Effect of lanthanum on methaold fuel exhaust deep oxidation over palladium catalyst 显示文摘 | Wang Xingji Wan Ying Lu Guanzhong | 2003 | Journal of Rare Earths2003，21，1： | 1 |
| 12 | Development of a new tissue-equivalent material applied to optimizing surgical accuracy显示文摘 | Jiang Shan Su Zhiliang Wang Xingji | 2013 | Materials Science and Engineering C-Materials for Biological Applications2013，33，7： | 1 |
| 13 | Mechanics-based bevel-tip needle deflection model during needle-soft tissue interaction process显示文摘 | Jiang Shan Wang Xingji Su Zhiliang | 2014 | Journal of Mechanics in Medicine and Biology2014，14，14： | 1 |
| 14 | An efficient method for global parameter sensitivity analysis and its applications to the Australian community land surface model (CABLE)显示文摘 | Lu Xingjie Wang Yingping Ziehn T | 2013 | Agricultural and Forest Meteorology2013，182，： | 1 |
| 15 | Hydroxypropyl-β-cyclodextrin copolymers and their nanoparticles as doxorubicin delivery system 显示文摘 | Wang Tiewei Zhang Chunling Liang Xingjie | 2011 | J Pharm Sci2011，100，3： | 1 |
| 16 | MiR-199a-3p promotes gastric cancer progression by targeting ZHX1显示文摘 | Zhenqiang Wang Xingjie Ma Qiang Cai Xinjing Wang Beiqin Yu Qu Cai Bingya liu Zhenggang Zhu Chen Li | 2014 | FEBS Letters2014，，： | 1 |
| 17 | Force modeling for needle insertion into soft tissue based on mechanical properties and geometric parameters显示文摘The force model during needle insertion into soft tissue is important for accurate percutaneous intervention.In this paper,a force model for needle insertion into a tissue- equivalent material is presented and a series of experiments are conducted to acquire data from needle soft- tissue interaction process.In order to build a more accurate insertion force model,the interaction force between a surgical needle and soft tissue is divided into three parts:stiffness force,friction force,and cutting force.The stiffness force is modeled on the basis of contact mechanics model.The friction force model is presented using a modified Winkler' s foundation model.The cutting force is viewed as a constant depending on a given tissue.The proposed models in the paper are established on the basis of the mechanical properties and geometric parameters of the needle and soft tissue.The experimental results illustrate that the force models are capable of predicting the needle-tissue interaction force.The force models of needle insertion can provide real-time haptic feedback for robot-assisted procedures,thereby improving the accuracy and safety of surgery. | 宿志亮 Jiang Shan Wang Xingji Yan Yu | 2014 | High Technology Letters2014，20，3： | 1 |
| 18 | An efficient method for global parameter sensitivity analysis and its applications to the Australian community land surface model (CABLE)显示文摘 | Xingjie Lu Ying-Ping Wang Tilo Ziehn Yongjiu Dai | 2013 | Agricultural and Forest Meteorology2013，，： | 1 |
| 19 | Moxibustion modulates working memory in patients with amnestic mild cognitive impairment:a functional magnetic resonance imaging study显示文摘OBJECTIVE:To investigate the correlation between changes in brain activity associated with working memory and assessment scales of memory scores in amnestic mild cognitive impairment(aMCI)before and after moxibustion therapy.METHODS:aMCI patients were randomized into the moxibustion treatment(MT)group and the placebo moxibustion(PM)group.Each group received either moxibustion therapy or a placebo moxibustion for eight weeks.Neuropsychological performance and functional brain responses to a working memory task were assessed at baseline and at the end of treatment.Memory function was evaluated individually by the Rivermead behavioral memory test(RBMT),and working memory was assessed by the N-back task.RESULTS:Compared with the PM group,RBMT score changes were significant(P<0.05).In the MT group,the accuracy of the N-back texts increased compared with those before the intervention.After moxibustion intervention,the right insula,postcentral gyrus,precentral gyrus,superior temporal gyrus,thalamus,lingual gyrus,calcarine sulcus,posterior cingulate gyrus,middle frontal gyrus and anterior frontal gyrus were significantly activated(P=0.01,Cluster-level Family-Wise Error=0.05).Pearson correlation analysis showed that the insula,lingual gyrus and posterior cingulate gyrus were associated with changes in N-back score.Spearman correlation analysis showed that the postcentral gyrus,superior temporal gyrus,thalamus,lingual gyrus,and posterior cingulate gyrus were correlated with RBMT score changes.CONCLUSION:Moxibustion treatment improved memory in aMCI patients and was associated with the activation of the brain region of the insula,lingual gyrus,posterior cingulate gyrus,postcentral gyrus,superior temporal gyrus,and thalamus,which may be an important mechanism by which moxibustion improves the memory function. | LI Xingjie LIU Qiqi XIA Rui LIU Jun WANG Dan SHI Jiao KUANG Yuxing DAI Yalan HUANG Haoyu TANG Wei CHEN Shangjie | 2023 | Journal of Traditional Chinese Medicine2023，43，4： | 1 |
| 20 | Preparation and characterization of doxorubicin functionalized tiopronin-capped gold nanorods for cancer therapy显示文摘Gold nanomaterials are immerging candidates in medical diagnosis and treatment.Among them,gold nanorods(Au NRs)are widely used for cancer treatment.Tiopronin as a novel thiol drug was used to stabilize Au NRs in this work.Doxorubicin(DOX),a chemotherapeutic drug which works by interacting with DNA to arrest the cell cycle and induce apoptosis,was linked to Au NRs through electrostatic reaction with tiopronin,to obtain Au-TIOP-DOX NRs.Au NRs are also regarded as hyperthermia agents for photothermal cancer treatment.This delivery system(Au-TIOP-DOX NRs)was designed for passively targeting tumor cells in cancer therapy.More importantly,the carboxyl groups of tiopronin can be modified with some biological molecules(DNA/RNA,peptides,or drugs)to make Au NRs as a novel drug-delivery system for cancer treatment. | HUO ShuaiDong JIN ShuBin ZHENG KaiYuan HE ShengTai WANG DongLiang LIANG XingJie | 2013 | Chinese Science Bulletin2013，58，33： | 1 |
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