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| 1 | Risk assessment and validation of flood disaster based on fuzzy mathematics显示文摘Floods often take place around rivers and plains,which indicates a higher risk of flooding in these areas.This paper adopts fuzzy comprehensive assessment(FCA),simple fuzzy classification(SFC),and the fuzzy similarity method(FSM) to assess flood disaster risk in Kelantan,Malaysia.Validation data,such as the flooded area,paddy area,urban area,residential area,and refuges,were overlaid to validate and analyze the accuracy of flood disaster risk.The results show that(1) 70-75% of flooded areas lie within the higher and high-est risk zones,which shows an effective assessment accuracy;(2) paddy,built-up,and residential areas concentrated in the higher and highest risk zones are more likely to be destroyed by flood disasters;(3) 200-225 refuges in the higher and highest risk zones account for around 50% of all refuges,which means that more refuges should be built in the higher and highest risk zones to meet the accommodation requirement;(4) three methods proved to be feasible and effective in evaluating flood disaster risk,among which FCA is more suitable for the study area than the two other methods. | Weiguo Jiang Lei Deng Luyao Chen Jianjun Wu Jing Li | 2009 | Progress in Natural Science:Materials International2009，19，10： | 35 |
| 2 | Distant eQTLs and Non-coding Sequences Play Critical Roles in Regulating Gene Expression and Quantitative Trait Variation in Maize显示文摘 | Haijun Liu Xin Luo Luyao Niu Yingjie Xiao Lu Chen Jie Liu Xiaqing Wang Minliang Jin Wenqiang Li Qinghua Zhang Jianbing Yan | 2017 | Molecular Plant2017，10，3： | 13 |
| 3 | Sintilimab versus docetaxel as second-line treatment in advanced or metastatic squamous non-small-cell lung cancer:an open-label,randomized controlled phase 3 trial(ORIENT-3)显示文摘Background:Treatment options for Chinese patients with locally advanced or metastatic squamous-cell non-small-cell lung cancer(sqNSCLC)after failure of first-line chemotherapy are limited.This study(ORIENT-3)aimed to evaluate the efficacy and safety of sintilimab versus docetaxel as second-line treatment in patients with locally advanced or metastatic sqNSCLC.Methods:ORIENT-3 was an open-label,multicenter,randomized controlled phase 3 trial that recruited patients with stage IIIB/IIIC/IV sqNSCLC after failure with first-line platinum-based chemotherapy.Patients were randomized in a 1:1 ratio to receive either 200 mg of sintilimab or 75 mg/m^(2) of docetaxel intravenously every 3 weeks,stratified by the Eastern Cooperative Oncology Group performance status.The primary endpoint was overall survival(OS)in the full analysis set(FAS).Secondary endpoints included progression-free survival(PFS),objective response rate(ORR),disease control rate(DCR),duration of response(DoR)and safety.Results:Between August 25,2017,and November 7,2018,290 patients were randomized.For FAS,10 patients fromthe docetaxel armwere excluded.Themedian OS was 11.79(n=145;95%confidence interval[CI],10.28-15.57)months with sintilimab versus 8.25(n=135;95%CI,6.47-9.82)months with docetaxel(hazard ratio[HR]:0.74;95%CI,0.56-0.96;P=0.025).Sintilimab treatment significantly prolonged PFS(median 4.30 vs.2.79 months;HR:0.52;95%CI,0.39-0.68;P<0.001)and showed higher ORR(25.50%vs.2.20%,P<0.001)and DCR(65.50%vs.37.80%,P<0.001)than the docetaxel arm.The median DoRwas 12.45(95%CI,4.86-25.33)months in the sintilimab arm and 4.14(95%CI,1.41-7.23)months in the docetaxel arm(P=0.045).Treatment-related adverse events of grade≥3were reported in 26(18.1%)patients in the sintilimab arm and 47(36.2%)patients in the docetaxel arm.Exploratory biomarker analysis showed potential predictive values of expression levels of two transcription factors,including OVOL2(HR:0.35;P<0.001)and CTCF(HR:3.50;P<0.001),for sintilimab treatment.Conclusions:Compared with docetaxel,sintilimab significantly improved the OS,PFS,and ORR of Chinese patients with previously treated locally advanced or metastatic sqNSCLC. | Yuankai Shi Lin Wu Xinmin Yu Puyuan Xing Yan Wang Jianying Zhou Airong Wang Jianhua Shi Yi Hu Ziping Wang Guangyu An Yong Fang Sanyuan Sun Caicun Zhou Changli Wang Feng Ye Xingya Li Junye Wang Mengzhao Wang Yunpeng Liu Yanqiu Zhao Ying Yuan Jifeng Feng Zhendong Chen Jindong Shi Tao Sun Gang Wu Yongqian Shu Qisen Guo Yi Zhang Yong Song Shucai Zhang Yuan Chen Wei Li Hongrui Niu Wenwei Hu Lijun Wang Jianan Huang Yang Zhang Ying Cheng Zhengdong Wu Bo Peng Jiya Sun Christoph Mancao Yanqi Wang Luyao Sun | 2022 | Cancer Communications2022，42，12： | 8 |
| 4 | The calcium-dependent protein kinase ZmCDPK7 functions in heat-stress tolerance in maize显示文摘Global warming poses a serious threat to crops.Calcium-dependent protein kinases(CDPKs)/CPKs play vital roles in plant stress responses,but their exact roles in plant thermotolerance remains elusive.Here,we explored the roles of heat-induced ZmCDPK7 in thermotolerance in maize.ZmCDPK7-overexpressing maize plants displayed higher thermotolerance,photosynthetic rates,and antioxidant enzyme activity but lower H2 O2 and malondialdehyde(MDA)contents than wild-type plants under heat stress.ZmCDPK7-knockdown plants displayed the opposite patterns.ZmCDPK7 is attached to the plasma membrane but can translocate to the cytosol under heat stress.ZmCDPK7 interacts with the small heat shock protein sHSP17.4,phosphorylates sHSP17.4 at Ser-44 and the respiratory burst oxidase homolog RBOHB at Ser-99,and up regulates their expression.Site-directed mutagenesis of sHSP17.4 to generate a Ser-44-Ala substitution reduced ZmCDPK7’s enhancement of catalase activity but enhanced ZmCDPK7’s suppression of MDA accumulation in heat-stressed maize protoplasts.sHSP17.4,ZmCDPK7,and RBOHB were less strongly upregulated in response to heat stress in the abscisic acid-deficient mutant vp5 versus the wild type.Pretreatment with an RBOH inhibitor suppressed sHSP17.4 and ZmCDPK7 expression.Therefore,abscisic acid-induced ZmCDPK7 functions both upstream and downstream of RBOH and participates in thermotolerance in maize by mediating the phosphorylation of sHSP17.4,which might be essential for its chaperone function. | Yulong Zhao Hanwei Du Yankai Wang Huali Wang Shaoyu Yang Chaohai Li Ning Chen Hao Yang Yihao Zhang Yulin Zhu Luyao Yang Xiuli Hu | 2021 | Journal of Integrative Plant Biology2021，63，3： | 6 |
| 5 | Harnessing the native type I-B CRISPR-Cas for genome editing in a polyploid archaeon显示文摘Research on CRISPR-Cas(clustered regularly interspaced short palindromic repeats-CRISPR associated protein) systems has led to the revolutionary CRISPR/Cas9 genome editing technique. However, for most archaea and half of bacteria, exploitation of their native CRISPR-Cas machineries may be more straightforward and convenient. In this study, we harnessed the native type I-B CRISPR-Cas system for precise genome editing in the polyploid haloarchaeon Haloarcula hispanica. After testing different designs, the editing tool was optimized to be a single plasmid that carries both the self-targeting miniCRISPR and a 600-800 bp donor. Significantly, chromosomal modifications, such as gene deletion, gene tagging or single nucleotide substitution, were precisely introduced into the vast majority of the transformants. Moreover, we showed that simultaneous editing of two genomic loci could also be readily achieved by one step. In summary, our data demonstrate that the haloarchaeal CRISPR-Cas system can be harnessed for genome editing in this polyploid archaeon, and highlight the convenience and efficiency of the native CRISPR-based genome editing strategy. | Feiyue Cheng Luyao Gong Dahe Zhao Haibo Yang Jian Zhou Ming Li Hua Xiang | 2017 | Journal of Genetics and Genomics2017，44，11： | 5 |
| 6 | Development of Cryogenic Disinfectants Using in-18℃and-40℃Environments—Worldwide,2021显示文摘Introduction:Since the outbreak of coronavirus disease 2019(COVID-19)in Beijing Xinfadi Wholesale Market,a series of COVID-19 outbreaks has indicated the threat of transmission due to outer surfaces of objects under low temperatures.Therefore,2 kinds of chlorine-containing disinfectants for−18℃and−40℃were developed in order to solve the problem of low temperature disinfection.Methods:The properties of two cryogenic disinfectants were evaluated by low-temperature test.Staphylococcus aureus and Escherichia coli were used as two indicator microorganisms to evaluate the effects of the two cryogenic disinfectants in the laboratory and field tests according to Technical Specifications for Disinfection(2002 version)and Test method for bactericidal effect of disinfectants in laboratory(GB/T 38502-2020).Results:Two disinfectants could remain in the liquid state at−18℃or−40℃in 72 hours without crystallization and precipitation,and the average log values of microbial reduction before and after disinfection(the average killing log value)both on Staphylococcus aureus and Escherichia coli were>3 in the laboratory and field tests.Discussion:The results showed that these two disinfectants remained functional at low temperature to disinfect the packaging of imported cold chain food and surrounding packaging to prevent transmission of COVID-19 from material to people. | Huihui Sun Hongyang Duan Wei Zhang Chen Liang Luyao Li Yuan Lyu Yanyan Chen Jin Shen Liubo Zhang | 2021 | China CDC weekly2021，3，13： | 4 |
| 7 | Silicon lithium-ion battery anode with enhanced performance: Multiple effects of silver nanoparticles显示文摘Silicon has been regarded as one of the most promising next generation lithium-ion battery anode. However, the poor cyclic stability of the Si based anode has severely limited its practical applications, which is even worse with high mass loading density(>1 mg cm^(-2)). A new concept has been developed to enhance the electrochemical performance of the Si nanoparticle anode. Silver nanoparticles are composited with the silicon nanoparticles in a facile way for the first time. It is found that the mechanical properties of the Si electrode have been significantly improved by the incorporation of the silver nanoparticles, leading to enhanced cyclic performance. With the Si/Ag mass ratio of 4:1, the reversible specific discharge capacity is retained as 1156 m A h g^(-1) after 100 cycles at 200 mA g^(-1), which is more than three times higher than that of the bare silicon(318 mA h g^(-1)). The rate performance has been effectively improved as well due to excellent electron conductivity of the silver nanoparticles. | Shanshan Yin Qing Jia Xiuxia Zuo Shuang Xie Kai Fang Yonggao Xia Jinlong Li Bao Qiu Meimei Wang Jianzhen Ban Xiaoyan Wang Yi Zhang Ying Xiao Luyao Zheng Suzhe Liang Zhaoping Liu Cundong Wang Ya-Jun Cheng | 2018 | Journal of Materials Science & Technology2018，34，10： | 4 |
| 8 | Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms显示文摘Titanium dioxide nanoparticles(TiO_2 NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO_2 NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. This review summarizes the toxic effects of TiO_2 NPs on multiple taxa of microorganisms, algae, plants, invertebrates, and vertebrates. The mechanism of TiO_2 NP toxicity to organisms can be outlined in three aspects: The Reactive Oxygen Species(ROS)produced by TiO_2 NPs following the induction of electron–hole pairs; cell wall damage and lipid peroxidation of the cell membrane caused by NP-cell attachment by electrostatic force owing to the large surface area of TiO_2 NPs; and TiO_2 NP attachment to intracellular organelles and biological macromolecules following damage to the cell membranes. | Jing Hou Luyao Wang Chunjie Wang Songlin Zhang Haiqiang Liu Shiguo Li Xiangke Wang | 2019 | Journal of Environmental Sciences2019，31，1： | 4 |
| 9 | Clinical phenotype of a Chinese patient with RIPK1 deficiency due to novel mutation显示文摘Accumulating evidence indicates that RIPK1 is associated with inflammation and apoptotic.RIPK1 deficiency leads to proinflammatory signaling impaired.However,only few patients with homozygous loss-of-function mutation in RIPK1 gene had been reported until now.Here,we report a Chinese combined immunodeficiency patient.He had recurrent infection,diarrhea after 3 months old.Immune function indicated that T,B and NK cells decreased significantly but immunoglobulins approximately remained normal.Whole-exome sequencing indicated that he had novel compound heterozygous mutations(c.998 C>A from his mother and c.1934 C>T from his father)in RIPK1 gene,which were confirmed by Sanger sequencing.Our study reports novel mutations in RIPK1 gene and new phenotype of patient with RIPK1 deficiency. | Li Lin Ying Wang Luyao Liu Wenjing Ying Wenjie Wang Bijun Sun Jinqiao Sun Xiaochuan Wang | 2020 | Genes & Diseases2020，7，1： | 3 |
| 10 | Engineering self-healing adhesive hydrogels with antioxidant properties for intrauterine adhesion prevention显示文摘Intrauterine adhesion (IUA) is the fibrosis within the uterine cavity. It is the second most common cause of female infertility, significantly affecting women’s physical and mental health. Current treatment strategies fail to provide a satisfactory therapeutic outcome for IUA patients, leaving an enormous challenge for reproductive science. A self-healing adhesive hydrogel with antioxidant properties will be highly helpful in IUA prevention. In this work, we prepare a series of self-healing hydrogels (P10G15, P10G20, and P10G25) with antioxidant and adhesive properties. Those hydrogels exhibit good self-healing properties and can adapt themselves to different structures. They possess good injectability and fit the shape of the human uterus. Moreover, the hydrogels exhibit good tissue adhesiveness, which is desirable for stable retention and therapeutic efficacy. The in vitro experiments using P10G20 show that the adhesive effectively scavenges ABTS+, DPPH, and hydroxyl radicals, rescuing cells from oxidative stress. In addition, P10G20 offers good hemocompatibility and in vitro and in vivo biocompatibility. Furthermore, P10G20 lowers down the in vivo oxidative stress and prevents IUA with less fibrotic tissue and better endometrial regeneration in the animal model. It can effectively downregulate fibrosis-related transforming growth factor beta 1 (TGF-β1) and vascular endothelial growth factor (VEGF). Altogether, these adhesives may be a good alternative for the clinical treatment of intrauterine adhesion. | Luyao Feng Liqun Wang Yao Ma Wanglin Duan Sergio Martin-Saldana Ye Zhu Xianpeng Zhang Bin Zhu Chaowei Li Shibo Hu Mingjie Bao Ting Wang Yuan Zhu Fei Yang Yazhong Bu | 2023 | Bioactive Materials2023，，9： | 3 |
| 11 | Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function显示文摘Innate immunity mediated by Toll-like receptors(TLRs),which can recognize pathogen molecular patterns,plays a critical role in type 1 diabetes development.TLR7 is a pattern recognition receptor that senses single-stranded RNAs from viruses and host tissue cells;however,its role in type 1 diabetes development remains unclear.In our study,we discovered that Tlr7-deficient(Tlr7^(−/−))nonobese diabetic(NOD)mice,a model of human type 1 diabetes,exhibited a significantly delayed onset and reduced incidence of type 1 diabetes compared with Tlr7-sufficient(Tlr7^(+/+))NOD mice.Mechanistic investigations showed that Tlr7 deficiency significantly altered B-cell differentiation and immunoglobulin production.Moreover,Tlr7^(−/−)NOD B cells were found to suppress diabetogenic CD4^(+)T-cell responses and protect immunodeficient NOD mice from developing diabetes induced by diabetogenic T cells.In addition,we found that Tlr7 deficiency suppressed the antigen-presenting functions of B cells and inhibited cytotoxic CD8^(+)T-cell activation by downregulating the expression of both nonclassical and classical MHC class I(MHC-I)molecules on B cells.Our data suggest that TLR7 contributes to type 1 diabetes development by regulating B-cell functions and subsequent interactions with T cells.Therefore,therapeutically targeting TLR7 may prove beneficial for disease protection. | Juan Huang Jian Peng James Alexander Pearson Georgios Efthimiou Youjia Hu Ningwen Tai Yanpeng Xing Luyao Zhang Jianlei Gu Jianping Jiang Hongyu Zhao Zhiguang Zhou F.Susan Wong Li Wen | 2021 | Cellular & Molecular Immunology2021，18，2： | 3 |
| 12 | Honeycomb-patterned films of polystyrene/poly(ethylene glycol): Preparation, surface aggregation and protein adsorption显示文摘Highly ordered honeycomb-patterned polystyrene (PS)/poly(ethylene glycol) (PEG) films were prepared by a water-assisted method using an improved setup, which facilitated the formation of films with higher regularity, better reproducibility, and larger area of honeycomb structures. Surface aggregation of hydrophilic PEG and adsorption of bovine serum albumin (BSA) on the honeycomb-patterned films were investigated. Field emission scanning electron microscopy (FESEM) and atomic force microscopy (AFM) were used to observe the surface morphologies of the films before and after being rinsed with water. As confirmed by the FESEM images and the AFM phase images, PEG was enriched in the pores and could be gradually removed by water. The adsorption of fluorescence-labeled BSA on the films was studied in visual form using laser scanning confocal microscopy. Results clearly demonstrated that the protein-resistant PEG was selectively enriched in the pores. This water-assisted method may be a latent tool to prepare honeycomb-patterned biofunctional surfaces. | WAN LingShu KE BeiBei LI XiaoKai MENG XiangLin ZHANG LuYao XU ZhiKang | 2009 | Science China Chemistry2009，52，7： | 3 |
| 13 | Microbiologically influenced corrosion of 304 stainless steel by halophilic archaea Natronorubrum tibetense显示文摘The corrosion behavior of 304 stainless steel(SS)in the presence of aerobic halophilic archaea Natronorubrum tibetense was investigated.After 14 days of immersion,no obvious pitting pit was observed on the SS surface in the sterile medium.By contrast,the SS exhibited serious pitting corrosion with the largest pit depth of 5.0μm in the inoculated medium after 14 days.The results of electrochemical tests showed that the barrier property of the passive film decreased faster in the inoculated medium.The X-ray photoelectron spectroscopy results indicated that the detrimental Fe2+and Cr6+increased in the passive film under the influence of archaea N.tibetense,which resulted in the accelerated deterioration of passive film and promoted the pitting corrosion.Combined with the energy starvation tests,the microbiologically influenced corrosion mechanism of 304 SS caused by halophilic archaea N.tibetense was discussed finally. | Hongchang Qian Lingwei Ma Dawei Zhang Ziyu Li Luyao Huang Yuntian Lou Cuiwei Du | 2020 | Journal of Materials Science & Technology2020，42，11： | 3 |
| 14 | Astragaloside Ⅳ suppresses post-ischemic natural killer cell infiltration and activation in the brain:involvement of histone deacetylase inhibition显示文摘Natural killer(NK)cells,a type of cytotoxic lymphocytes,can infiltrate into ischemic brain and exacerbate neuronal cell death.Astragaloside Ⅳ(ASIV)is the major bioactive ingredient of Astragalus membranaceus,a Chinese herbal medicine,and possesses potent immunomodulatory and neuroprotective properties.This study investigated the effects of ASIV on post-ischemic brain infiltration and activation of NK cells.ASIV reduced brain infarction and alleviated functional deficits in MCAO rats,and these beneficial effects persisted for at least 7 days.Abundant NK cells infiltrated into the ischemic hemisphere on day 1 after brain ischemia,and this infiltration was suppressed by ASIV.Strikingly,ASIV reversed NK cell deficiency in the spleen and blood after brain ischemia.ASIV inhibited astrocyte-derived CCL2 upregulation and reduced CCR2+NK cell levels in the ischemic brain.Meanwhile,ASIV attenuated NK cell activating receptor NKG2D levels and reduced interferon-γproduction.ASIV restored acetylation of histone H3 and the p65 subunit of nuclear factor-κB in the ischemic brain,suggesting inhibition of histone deacetylase(HDAC).Simultaneously,ASIV prevented p65 nuclear translocation.The effects of ASIV on reducing CCL2 production,restoring acetylated p65 levels and preventing p65 nuclear translocation were mimicked by valproate,an HDAC inhibitor,in astrocytes subjected to oxygen-glucose deprivation.Our findings suggest that ASIV inhibits post-ischemic NK cell brain infiltration and activation and reverses NK cell deficiency in the periphery,which together contribute to the beneficial effects of ASIV against brain ischemia.Furthermore,ASIV’s effects on suppressing NK cell brain infiltration and activation may involve HDAC inhibition. | Baokai Dou Shichun Li Luyao Wei Lixin Wang Shiguo Zhu Zhengtao Wang Zunji Ke Kaixian Chen Zhifei Wang | 2021 | Frontiers of Medicine2021，15，1： | 3 |
| 15 | A core-shell structured COYID-19 mRNA vaccine with favorable biodistribution pattern and promising immunity显示文摘Although inoculation of COVID-19 vaccines has rolled out globally,there is still a critical need for safe and effective vaccines to ensure fair and equitable supply for all countries.Here,we report on the development of a highly efficacious mRNA vaccine,SW0123 that is composed of sequence-modified mRNA encoding the full-length SARS-CoV-2 Spike protein packaged in core-shell structured lipopolyplex(LPP)nanoparticles.SWOT 23 is easy to produce using a large-scale microfluidics-based apparatus.The unique core-shell structured nanoparticle facilitates vaccine uptake and demonstrates a high colloidal stability,and a desirable biodistribution pattern with low liver targeting effect upon intramuscular administration.Extensive evaluations in mice and nonhuman primates revealed strong immunogenicity of SW0123,represented by induction of Th1-polarized T cell responses and high levels of antibodies that were capable of neutralizing not only the wild-type SARS-CoV-2,but also a panel of variants including D614G and N501Y variants.In addition,SW0123 conferred effective protection in both mice and non-human primates upon SARS-CoV-2 challenge.Taken together,SW0123 is a promising vaccine candidate that holds prospects for further evaluation in humans. | Ren Yang Yao Deng Baoying Huang Lei Huang Ang Lin Yuhua Li Wenling Wang Jingjing Liu Shuaiyao Lu Zhenzhen Zhan Yufei Wang Ruhan A Wen Wang Peihua Niu Li Zhao Shiqiang Li Xiaopin Ma Luyao Zhang Yujian Zhang Weiguo Yao Xingjie Liang Jincun Zhao Zhongmin Liu Xiaozhong Peng Hangwen Li Wenjie Tan | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 3 |
| 16 | Rolling texture development in a dual-phase Mg-Li alloy:The role of temperature显示文摘Dual-phase Mg-Li alloys sheets were rolled at four different temperatures ranging from liquid nitrogen to 300℃to explore effect of rolling temperature on texture and mechanical properties of the material.Crystal plasticity simulation was utilized to illustrate the influence of slip activity on rolling texture development.The results show that the rolling texture is largely depended on deformation temperature.Unlike commercial Mg alloys,the critical resolved shear stress of basal slip inα-Mg phase of Mg-Li alloy decreased more significantly by increasing temperature compared to that of pyramidalslip.Enhancement of basal slip by increasing temperature triggered a decrease of split angle of basal poles for the double-peak texture.Prismaticslip largely enhanced by increasing temperature upon 200℃,which induced a wider orientation spread along the transverse direction.For theβ-Li phase,the promotion of{110}<111>slip system at elevated temperature triggered the enhancement of{211}<110>and{111}<211>texture components.The cryo-rolled sample exhibited the highest strength compared to the others due to a strong hardening behavior at this temperature.A two-stage hardening behavior was observed in these as-rolled dual-phase alloys.Strain transition at phase boundaries could be the reason for appearance of this two-stage hardening. | Xiaoyan Li Fei Guo Yanlong Ma Luyao Jiang Hongliang Lai Haiding Liu Dingfei Zhang Risheng Pei | 2023 | Journal of Magnesium and Alloys2023，11，8： | 2 |
| 17 | Submicrosecond electro-optical switching of one-dimensional soft photonic crystals显示文摘Soft photonic crystals are appealing due to their self-assembly ability,wide tunability,and multistimuli-responsiveness.However,their response time is relatively slow,ranging from milliseconds to minutes.Here,we report submicrosecond switching of chiral liquid crystals(LCs)with 1D photonic microstructures,where electric fields modify the orientational order of molecules and quench their fluctuations,rather than altering the orientation.Thus,the adjusted refractive indices result in a fast shift of the photonic bandgap,on the order of 100 ns,which is four orders of magnitude faster than conventional electro-optic switching in cholesterics.This work offers tremendous opportunities for soft photonic applications. | Lingling Ma Chaoyi Li Luyao Sun Zhenpeng Song Yanqing Lu Bingxiang Li | 2022 | Photonics Research2022，10，3： | 2 |
| 18 | Taking the pulse of COVID-19:a spatiotemporal perspective显示文摘The sudden outbreak of the Coronavirus disease(COVID-19)swept across the world in early 2020,triggering the lockdowns of several billion people across many countries,including China,Spain,India,the U.K.,Italy,France,Germany,Brazil,Russia,and the U.S.The transmission of the virus accelerated rapidly with the most confirmed cases in the U.S.,India,Russia,and Brazil.In response to this national and global emergency,the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implementation strategies to rapidly respond to this crisis,for supporting research,saving lives,and protecting the health of global citizens.This perspective paper presents our collective view on the global health emergency and our effort in collecting,analyzing,and sharing relevant data on global policy and government responses,human mobility,environmental impact,socioeconomical impact;in developing research capabilities and mitigation measures with global scientists,promoting collaborative research on outbreak dynamics,and reflecting on the dynamic responses from human societies. | Chaowei Yang Dexuan Sha Qian Liu Yun Li Hai Lan Weihe Wendy Guan Tao Hu Zhenlong Li Zhiran Zhang John Hoot Thompson Zifu Wang David Wong Shiyang Ruan Manzhu Yu Douglas Richardson Luyao Zhang Ruizhi Hou You Zhoua Cheng Zhong Yifei Tian Fayez Beaini Kyla Carte Colin Flynn Wei Liu Dieter Pfoser Shuming Bao Mei Li Haoyuan Zhang Chunbo Liu Jie Jiang Shihong Du Liang Zhao Mingyue Lu Lin Li Huan Zhou Andrew Ding | 2020 | International Journal of Digital Earth2020，13，10： | 2 |
| 19 | Lanthanum-dopedα-Ni(OH)_(2)1D-2D-3D hierarchical nanostructures for robust bifunctional electro-oxidation显示文摘The development of advanced electrocatalysts for electro-oxidation reactions has attracted much attention because of the critical role of such electrocatalysts in improving the overall efficiency of coupled hydrogen production.We have developed an efficient lanthanum-dopedα-Ni(OH)_(2) bifunctional catalyst with a 1D-2D-3D hierarchical nanostructure.It shows superior activity and stability in the anodic oxygen evolution reaction(OER)and urea oxidation reaction(UOR).Enrichment of the edge sites and conducting La doping inα-Ni(OH)_(2) phase enable formation and stabilization of abundant local Ni^(3+)ions.This guarantees ultralow onset potentials in electro-oxidation reactions.The 1D-2D-3D hierarchical nanostructure significantly boosts the in situ generation of high-valence active species,which results in efficient and stable OER and UOR performances,and the synergistic merit of doping-induced facile reaction kinetics.Because of the structural benefits of a large surface area,charge-transfer promotion,good structural stability,and bifunctionality,a 1%La-dopedα-Ni(OH)_(2) hierarchical nanostructure gives superior OER and UOR performances with low overpotentials,large catalytic current densities,and excellent operational stability.It is therefore a promising catalyst for use in simultaneous alkaline wastewater treatment and hydrogen production. | Zimeng Wei Wenbin Sun Shanshan Liu Jindi Qi Luyao Kang jiechen Li Shanshan Lou Junfeng Xie Bo Tanga Yi Xie | 2021 | Particuology2021，19，4： | 1 |
| 20 | Synthesis and unusual proper- ties of novel alkyl benzene sulfonate Gemini surfaetants显示文摘 | Duan Xi gang LuYao Li Ling | 2006 | Colloids Surf A2006，290，： | 1 |
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