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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Nonlinear phenomena of three-dimensional liquid sloshing in microgravity environment显示文摘The dynamic problem of three-dimen- sional liquid sloshing is numerically studied in this paper. The arbitrary Lagrange-Euler (ALE) kinematic description is introduced into the control equations system. The discrete numerical equations of finite element method are developed by Galerkin weighted residual method. The boundary condition about free-surface tension is represented in the form of weak integration that can be computed by our dif- ferential geometry method derived. The normal vec- tor on free surface is calculated by using accurate formula presented in this paper. The numerical computations are performed and the comparison not only between numerical results and analytical results but also between numerical results and experimental results validated the effectiveness of the method. Finally, large amplitude sloshing of three-dimensional liquid in low-gravity environment is simulated and some important nonlinear characteristics are ob- tained. From the numerical results, it is concluded that the character of nonlinear sloshing of the liquid under low-gravity environment is much different from that of the liquid sloshing under normal gravity envi- ronment. | YUE Baozeng WANG Zhaolin | 2006 | Chinese Science Bulletin2006，51，20： | 16 |
| 3 | EFFECT OF NANOCRYSTALLIZATION ON OXIDATION RESISTANCE OF TiAl INTERMETALLIC COMPOUND显示文摘EFFECTOFNANOCRYSTALLIZATIONONOXIDATIONRESISTANCEOFTiAlINTERMETALLICCOMPOUND①TangZhaolin,WangFuhui,WuWeitaoNationalKeyLaborato... | Tang Zhaolin , Wang Fuhui , Wu Weitao National Key Laboratory for Corrosion and Protection, Young Scientists Laboratory of Surface Engineering, Institute of Corrosion and Protection of Metals, Chinese Academy of Sciences, Shenyang 110015 | 1997 | 中国有色金属学会会刊:英文版1997，7，2： | 13 |
| 4 | Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells显示文摘RNase III DROSHA is upregulated in multiple cancers and contributes to tumor progression by hitherto unclear mechanisms.Here,we demonstrate that DROSHA interacts withβ-Catenin to transactivate STC1 in an RNA cleavage-independent manner,contributing to breast cancer stem-like cell(BCSC)properties.DROSHA mRNA stability is enhanced by N6-methyladenosine(m^(6)A)modification which is activated by AURKA in BCSCs.AURKA stabilizes METTL14 by inhibiting its ubiquitylation and degradation to promote DROSHA mRNA methylation.Moreover,binding of AURKA to DROSHA transcript further strengthens the binding of the m^(6)A reader IGF2BP2 to stabilize m^(6)A-modified DROSHA.In addition,wild-type DROSHA,but not an m^(6)A methylation-deficient mutant,enhances BCSC stemness maintenance,while inhibition of DROSHA m^(6)A modification attenuates BCSC traits.Our study unveils the AURKA-induced oncogenic m^(6)A modification as a key regulator of DROSHA in breast cancer and identifies a novel DROSHA transcriptional function in promoting the BCSC phenotype. | Fei Peng Jie Xu Bai Cui Qilan Liang Sai Zeng Bin He Hong Zou Manman Li Huan Zhao Yuting Meng Jin Chen Bing Liu Shasha Lv Peng Chu Fan An Zifeng Wang Junxiu Huang Yajing Zhan Yuwei Liao Jinxin Lu Lingzhi Xu Jin Zhang Zhaolin Su Zhiguang Li Fangjun Wang Eric W-FLam Quentin Liu | 2021 | Cell Research2021，31，3： | 9 |
| 5 | Numerical study of three-dimensional free surface dynamics显示文摘三维的免费表面的动态问题数字地在这篇论文被学习。淡色啤酒(任意的 Lagrange-Euler ) 运动学的描述被介绍进控制方程系统。淡色啤酒描述方法被用来追踪免费表面。为推测免费表面上的正常向量被介绍的精确明确的表达。由有限元素方法的分离数字方程被 Galerkin 加权的剩余方法开发。关于免费表面的紧张的边界条件在弱集成形式被代表能被在现在的纸导出的一个微分几何学方法计算。接触角的效果在数字算法被合并。而且,数字计算被执行,在计算、分析的结果之间的比较验证了方法的有效性。这篇论文的结果提供液体的动力学的理解释放的一个基础表面,表面紧张和接触角边界在调节被考虑。最后,在一只圆柱的集装箱的液体的大规模振幅 sloshing 的数字模拟被执行并且效果的数字分析一环形圆形的僵硬抑制在圆(筒形) 槽的液体 sloshing 摆动上的 baffle 也被执行。 | Baozeng Yue Zhaolin Wang | 2006 | Acta Mechanica Sinica2006，22，2： | 9 |
| 6 | Reinforcement Learning-Based Joint Task Offloading and Migration Schemes Optimization in Mobility-Aware MEC Network显示文摘Intelligent edge computing carries out edge devices of the Internet of things(Io T) for data collection, calculation and intelligent analysis, so as to proceed data analysis nearby and make feedback timely. Because of the mobility of mobile equipments(MEs), if MEs move among the reach of the small cell networks(SCNs), the offloaded tasks cannot be returned to MEs successfully. As a result, migration incurs additional costs. In this paper, joint task offloading and migration schemes in mobility-aware Mobile Edge Computing(MEC) network based on Reinforcement Learning(RL) are proposed to obtain the maximum system revenue. Firstly, the joint optimization problems of maximizing the total revenue of MEs are put forward, in view of the mobility-aware MEs. Secondly, considering time-varying computation tasks and resource conditions, the mixed integer non-linear programming(MINLP) problem is described as a Markov Decision Process(MDP). Then we propose a novel reinforcement learning-based optimization framework to work out the problem, instead traditional methods. Finally, it is shown that the proposed schemes can obviously raise the total revenue of MEs by giving simulation results. | Dongyu Wang Xinqiao Tian Haoran Cui Zhaolin Liu | 2020 | China Communications2020，17，8： | 7 |
| 7 | Study on Characteristics of Co-firing Ammonia/Methane Fuels under Oxygen Enriched Combustion Conditions显示文摘Having a background of utilising ammonia as an alternative fuel for power generation, exploring the feasibility of co-firing ammonia with methane is proposed to use ammonia to substitute conventional natural gas. However, improvement of the combustion of such fuels can be achieved using conditions that enable an increase of oxygenation, thus fomenting the combustion process of a slower reactive molecule as ammonia. Therefore, the present study looks at oxygen enriched combustion technologies, a proposed concept to improve the performance of ammonia/methane combustion. To investigate the characteristics of ammonia/methane combustion under oxygen enriched conditions, adiabatic burning velocity and burner stabilized laminar flame emissions were studied. Simulation results show that the oxygen enriched method can help to significantly enhance the propagation of ammonia/methane combustion without changing the emission level, which would be quite promising for the design of systems using this fuel for practical applications. Furthermore, to produce low computational-cost flame chemistry for detailed numerical analyses for future combustion studies, three reduced combustion mechanisms of the well-known Konnov's mechanism were compared in ammonia/methane flame simulations under practical gas turbine combustor conditions. Results show that the reduced reaction mechanisms can provide good results for further analyses of oxygen enriched combustion of ammonia/methane. The results obtained in this study also allow gas turbine designers and modellers to choose the most suitable mechanism for further combustion studies and development. | XIAO Hua WANG Zhaolin VALERA-MEDINA Agustin BOWEN Philip J | 2018 | Journal of Thermal Science2018，27，3： | 6 |
| 8 | Applications of membrane distillation technology in energy transformation process-basis and prospect显示文摘Membrane distillation technology is a new type of efficient separation technology that combines traditional distillation technology and membrane separation technology. In the study, applications of membrane distillation technology in thermal engineering and refrigerating engineering with typical energy transformation process were presented. Desorption and regeneration process of saline solution by vacuum membrane distillation was proposed on the basis of the concentration and separation properties of membrane distillation. Membrane distillation technology could be used in lithium bromide absorption refrigeration system, energy storage system, and the regeneration process of liquid desiccant solution in temperature-humidity independent control air-conditioning system. The aim of the applications was to use the low-grade energy such as waste heat, solar energy and geothermal energy adequately and to improve the available temperature difference of heat source. According to latent heat transfer and thermal conduction across the membrane in direct contact membrane distillation process, a novel membrane heat exchanger with both heat transfer and mass transfer processes was proposed. The heat exchanger could be used as the solution heat exchanger of lithium bromide absorption refrigeration system and as the special heat exchanger that recovered heat and pure water simultaneously. Some feasible process flows about the applications of membrane distillation technology to energy transformation process were listed and analyzed. Finally, future research emphases were indicated. | WANG ZanShe GU ZhaoLin FENG ShiYu LI Yun | 2009 | Chinese Science Bulletin2009，54，16： | 6 |
| 9 | High-Energy Batteries:Beyond Lithium-Ion and Their Long Road to Commercialisation显示文摘Rechargeable batteries of high energy density and overall performance are becoming a critically important technology in the rapidly changing society of the twenty-first century.While lithium-ion batteries have so far been the dominant choice,numerous emerging applications call for higher capacity,better safety and lower costs while maintaining sufficient cyclability.The design space for potentially better alternatives is extremely large,with numerous new chemistries and architectures being simultaneously explored.These include other insertion ions(e.g.sodium and numerous multivalent ions),conversion electrode materials(e.g.silicon,metallic anodes,halides and chalcogens)and aqueous and solid electrolytes.However,each of these potential“beyond lithium-ion”alternatives faces numerous challenges that often lead to very poor cyclability,especially at the commercial cell level,while lithium-ion batteries continue to improve in performance and decrease in cost.This review examines fundamental principles to rationalise these numerous developments,and in each case,a brief overview is given on the advantages,advances,remaining challenges preventing cell-level implementation and the state-of-the-art of the solutions to these challenges.Finally,research and development results obtained in academia are compared to emerging commercial examples,as a commentary on the current and near-future viability of these“beyond lithium-ion”alternatives. | Yulin Gao Zhenghui Pan Jianguo Sun Zhaolin Liu John Wang | 2022 | Nano-Micro Letters2022，14，6： | 5 |
| 10 | Methods for large reciprocating compressor capacity control: A review based on pulse signal concept显示文摘Large reciprocating compressors are important equipment used in a wide range of process industries. Most of these compressors have huge power requirements and their capacity often needs to be regulated. Advanced technologies in compressor capacity control are effective approaches for saving large amounts of energy in process industries. This paper reviews the basic theories and the state of the art of the capacity control technologies. In particular, a compressor working procedure is first presented using an analogy to the pulse signal concept. Compressor capacity control methods are classified into pulse frequency modulation and pulse amplitude modulation from a perspective of pulse signal processing. The mechanisms and feasibility of some important methods, including dead volume variable control, partial-stroke and full-stroke suction valve opening, are reviewed. Based on the pulse signal concept, a duty cycle regulation method for capacity control is introduced, and the performance and implementation of the new method are compared with those of the existing suction valve opening methods. The duty cycle regulation method has integrated advantages over the other methods in terms of regulating precision, pressure stability, energy saving and reliability. All the suction valve opening methods can cause gas reflux, resulting in the so-called breathing effect. The breathing effect has negative effects on regulation performance and compressor security, which needs further investigation in the future. | GU ZhaoLin HOU XiongPo WANG ZanShe FENG ShiYu GAO XiuFeng LI Yun | 2011 | Chinese Science Bulletin2011，56，19： | 4 |
| 11 | Effects and mechanism of freeze-thawing cycles on the soil N2O fluxes in the temperate semi-arid steppe显示文摘High nitrous oxide(N2O) emissions during freeze-thawing period(FTP) have been observed in many different ecosystems. However, the knowledge about the dynamic of soil N_2O emissions and its main driving mechanism during the freeze-thawing processes in grassland ecosystem is still limited. An in-situ experiment was conducted during the FTP on the sites with 0 and 15% surplus of the average rainfall and two levels of N addition(0,10 g N/(m^2·year)) during growing season(marked as W0N0, W15N0, W0N10, W15N10, respectively) to explore the effects of water and N background on soil N_2O emissions during FTPs and the relationship between soil N_2O emissions and environmental factors. The results indicated that water and N treatments conducted during growing season did not show significant effect on the N_2O effluxes of FTP, but the soil mineral N contents of W0N10 treatment were significantly higher than those of W0N0, W15N0, W15N10treatments(p < 0.05). The soil PLFA concentrations of microbial groups monitored during 2015 spring freeze-thawing period(2015S-FTP) were lower than those during winter freeze-thawing period of 2014(2014W-FTP), while cumulative soil N_2O emissions of 2015S-FTP were higher than those of 2014W-FTP. The correlations between soil N_2O effluxes and most of the measured environmental factors were insignificant, multiple stepwise regression analysis indicated that the soil temperature, soil NH_4^+-N content and air temperature were the major environmental factors which significantly influenced the N_2O effluxes during 2014W-FTP, and air temperature and soil water content were the significant influencing factors during 2015S-FTP. | Liqin Wang Yuchun Qi Yunshe Dong qin Peng Shufang Guo Yunlong He Zhaolin Li | 2017 | Journal of Environmental Sciences2017，29，6： | 4 |
| 12 | Rational structure design to realize high-performance SiOx@C anode material for lithium ion batteries显示文摘Silicon suboxide(SiOx)is considered to be one of the most promising materials for next-generation anode due to its high energy density.For its preparation,the wet-chemistry method is a cost-effective and readily scalable route,while the so-derived SiOx usually shows lower capacity compared with that prepared by high temperature-vacuum evaporation route.Herein,we present an elaborate particle structure design to realize the wet-chemistry preparation of a high-performance SiOx/C nanocomposite.Dandelion-like highly porous SiOx particle coated with conformal carbon layer is designed and prepared.The highly-porous SiOx skeleton provides plenty specific surface for intimate contact with carbon layer to allow a deep reduction of SiOx to a low O/Si ratio at relatively low temperature(700℃),enabling a high specific capacity.The abundant mesoscale voids effectively accommodate the volume variation of SiOx skeleton,ensuring the high structural stability of SiOx@C during lithiation/delithiation process.Meanwhile,the three-dimensional(3D)conformal carbon layer provides a fast electron/ion transportation,allowing an enhanced electrodereaction kinetics.Owing to the optimized O/Si ratio and well-engineered structure,the prepared SiOx@C electrode delivers an ultra-high capacity(1,115.8 mAh·g^-1 at 0.1 A·g^-1 after 200 cycles)and ultra-long lifespan(635 mAh·g^-1 at 2 A·g^-l after 1,000 cycles).To the best of our knowledge,the achieved combination of ultra-high specific capacity and ultra-long cycling life is unprecedented. | Zhaolin Li Hailei Zhao Jie Wang Tianhou Zhang Boyang Fu Zijia Zhang Xin Tao | 2020 | Nano Research2020，13，2： | 3 |
| 13 | Effect of Sputtered TiAlCr Coatings on Oxidation and Hot Corrosion Resistance of Ti-24Al-14Nb-3V显示文摘The effect of sputtered Ti-50Al-10Cr and Ti-50A1-20Cr coatings on both isothermal and cyclic oxidation resistance at 800-900℃ and hot corrosion resistance at 850℃ of Ti-24Al-14Nb-3V was investigated. Results indicated that Ti-24Al-14Nb-3V alloys exhibited poor oxidation resistance due to the formation of Al2O3+TiO2+AlNbO4 mixed scales in air at 800-900℃ and poor hot corrosion resistance due to the spoliation of scales formed in Na2SO4+K2SO4 melts at 850℃. Both Ti-50Al-10Cr and Ti-50Al-20Cr coatings remarkably improved the oxidation and hot corrosion resistance of Ti-24Al-14Nb-3V alloy. | Fuhui WANG, Chunhong GUAN, Zhaolin TANG and Weitao WU State Key Laboratory for Corrosion and Protection, Institute of Metal Research, The Chinese Academy of Sciences, Shenyang 110016, China | 2001 | Journal of Materials Science & Technology2001，17，5： | 2 |
| 14 | Effects of root dominate over aboveground litter on soil microbial biomass in global forest ecosystems显示文摘Background:Inputs of above-and belowground litter into forest soils are changing at an unprecedented rate due to continuing human disturbances and climate change.Microorganisms drive the soil carbon(C)cycle,but the roles of above-and belowground litter in regulating the soil microbial community have not been evaluated at a global scale.Methods:Here,we conducted a meta-analysis based on 68 aboveground litter removal and root exclusion studies across forest ecosystems to quantify the roles of above-and belowground litter on soil microbial community and compare their relative importance.Results:Aboveground litter removal significantly declined soil microbial biomass by 4.9%but root exclusion inhibited it stronger,up to 11.7%.Moreover,the aboveground litter removal significantly raised fungi by 10.1%without altering bacteria,leading to a 46.7%increase in the fungi-to-bacteria(F/B)ratio.Differently,root exclusion significantly decreased the fungi by 26.2%but increased the bacteria by 5.7%,causing a 13.3%decrease in the F/B ratio.Specifically,root exclusion significantly inhibited arbuscular mycorrhizal fungi,ectomycorrhizal fungi,and actinomycetes by 22.9%,43.8%,and 7.9%,respectively.The negative effects of aboveground litter removal on microbial biomass increased with mean annual temperature and precipitation,whereas that of root exclusion on microbial biomass did not change with climatic factors but amplified with treatment duration.More importantly,greater effects of root exclusion on microbial biomass than aboveground litter removal were consistent across diverse forest biomes(expect boreal forests)and durations.Conclusions:These data provide a global evidence that root litter inputs exert a larger control on microbial biomass than aboveground litter inputs in forest ecosystems.Our study also highlights that changes in above-and belowground litter inputs could alter soil C stability differently by shifting the microbial community structure in the opposite direction.These findings are useful for predicting microbe-mediated C processes in response to changes in forest management or climate. | Yanli Jing Peng Tian Qingkui Wang Weibin Li Zhaolin Sun Hong Yang | 2021 | Forest Ecosystems2021，8，3： | 2 |
| 15 | Screening,identification and antagonistic effect of antagonistic bacteria JTFM1001 against aflatoxin contamination in corn显示文摘Aflatoxin is a strong carcinogenic and toxic fungal toxin produced by Aspergillus flavus and other Aspergillus species,and can seriously threaten the health of consumers,thus becoming a global concern.Corn,as an important oil and economic crop,is highly susceptible contaminated by aflatoxin.In this study,antagonistic bacteria with strong inhibitory effect on aflatoxin were screened to provide support for the treatment aflatoxin contamination control in corn.Ten strains which have strong antagonistic effects against A.flavus were isolated from healthy corn from different corn producing areas in China.Among them,the antagonistic bacteria JTFM1001 through corn kernels in vivo and field experiment,the inhibition effect of aflatoxin contamination reached above 70%and 55%,respectively.And the strain was identified as Bacillus subtilis based on its morphological,physiological and biochemical characteristics and phylogenetic analysis of 16S rDNA.In addition,our data showed that it can colonize in the rhizosphere and survive for a long time,forming the dominant flora,with broad application prospect.Finally,we were surprised to find that the antibacterial metabolites secreted by the antagonistic bacteria was one of the mechanisms of its inhibition of A.flavus and aflatoxin.This will provide us with new ideas and perspectives on the effective prevention and control of aflatoxin contamination in corn and corn oil. | Jing Zhang Yu Wang Zhaolin Du Dasong Lin Lili Huo Li Qin Wei Wang Liwen Qiang Yanpo Yao Yi An | 2021 | Oil Crop Science2021，6，1： | 2 |
| 16 | Viscoelastic plate-fluid interactive vibration and liquid sloshing suppression显示文摘 | Wang Zhaolin Quan Bin Cheng Xuduo | 1990 | Acta Mechanica Sinica1990，，3： | 1 |
| 17 | Low-temperature processing of Fe-Al intermetallic coatings assisted by ball milling显示文摘 | Zhan Zhaolin He Yedong Wang Deren | 2006 | Intermetallics2006，14，1： | 1 |
| 18 | An assessment of regional water resource based on water footprint:A case study of Chonqqing Municipality显示文摘 | Wang Zhaolin Yang Qingyuan Lu Chunyang | 2007 | Journal of Southwest University (Natural Science Edition)2007，29，8： | 1 |
| 19 | Hot-corrosion behavior of TiAl-base intermetallics in molten salts显示文摘 | Tang Zhaolin Wang Fuhui Wu Weitao | 1999 | Oxid Met1999，51，34： | 1 |
| 20 | Hot-corro sion behavior of TiAl-base intermetallics in molten salts 显示文摘 | Tang Zhaolin Wang Fuhui Wu Weitao | 1999 | Oxid Met1999，51，34： | 1 |
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