|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 3 | Integrated transcriptomic and metabolomic analyses of a wax deficient citrus mutant exhibiting jasmonic acid-mediated defense against fungal pathogens显示文摘Naturally,resistant crop germplasms are important resources for managing the issues of agricultural product safety and environment deterioration.We found a spontaneous mutant of‘Newhall’navel orange(Citrus sinensis Osbeck)(MT)with broad-spectrum protections against fungal pathogens in the orchard,postharvest-storage,and artificial inoculation conditions.To understand the defense mechanism of MT fruit,we constructed a genome-scale metabolic network that integrated metabolome and transcriptome datasets.The coordinated transcriptomic and metabolic data were enriched in two sub-networks,showing the decrease in very long chain fatty acid(by 41.53%)and cuticular wax synthesis(by 81.34%),and increase in the synthesis of jasmonic acid(JA)(by 95.23%)and JA-induced metabolites such as 5-dimethylnobietin(by 28.37%)in MT.Furthermore,cytological and biochemical analyses confirmed that the response to fungal infection in MT was independent of wax deficiency and was correlated with the levels of jasmonates,and the expression of plant defensin gene PDF1.2.Results of exogenous application of MeJA and JA inhibitors such as propyl gallate proved that JA-mediated defense contributes to the strong tolerance against pathogens in MT.Our results indicated that jasmonate biosynthesis and signaling are stimulated by the fatty acid redirection of MT,and participate in the tolerance of pathogenic fungi. | Yizhong He Jingwen Han Runsheng Liu Yuduan Ding Jinqiu Wang Li Sun Xiaoming Yang Yunliu Zeng Weiwei Wen Juan Xu Hongming Zhang Xiang Yan Zhaoxing Chen Zuliang Gu Hong Chen Huanqing Tang Xiuxin Deng Yunjiang Cheng | 2018 | Horticulture Research2018，5，1： | 8 |
| 4 | Baicalein suppresses vasculogenic mimicry through inhibiting RhoA/ROCK expression in lung cancer A549 cell line显示文摘Vasculogenic mimicry(VM)refers to a new tubular network of the blood supply system with abundant extracellular matrix.VM is similar to capillaries but does not involve endothelial cells.As a traditional herbal medicine commonly used in China,baicalein possesses anti-inflammatory and lipoxygenase activities.However,the effects of baicalein on the process of VM formation in nonsmall cell lung cancer(NSCLC)and the underlying mechanisms have remained poorly understood.In this study,baicalein was found to inhibit the viability and motility of A549 cells and induced the breakage of the cytoskeletal actin filament network.In addition,baicalein significantly decreased the formation of VM and downregulated the expressions of VM-associated factors,such as VEcadherin,EphA2,MMP14,MMP2,MIVIP9,PI3K and LAMC2,similar to the effects of ROCK inhibitors.In deed,baicalei n inhibited RhoA/ROCK expression in vitro and in vivo,suggesting the underlying mechanisms of reduced VM formation.Collectively,baicalein suppressed the formation of VM in NSCLC by targeting the RhoA/ROCK signaling pathway,indicating that baicalein might serve as an emerging drug for NSCLC. | Zhe Zhang Li Nong Menglei Chen Xiaoli Gu Weiwei Zhao Minghui Liu Wenwu Cheng | 2020 | Acta Biochimica et Biophysica Sinica2020，52，9： | 5 |
| 5 | Synchrotron radiation-based Fourier-transform infrared spectromicroscopy for characterization of the protein/peptide distribution in single microspheres显示文摘The present study establishes a visualization method for the measurement of the distribution and localization of protein/peptide constituents within a single poly-lactide-co-glycolide(PLGA) microsphere using synchrotron radiation–based Fourier-transform infrared spectromicroscopy(SR-FTIR).The representative infrared wavenumbers specific for protein/peptide(Exenatide) and excipient(PLGA) were identified and chemical maps at the single microsphere level were generated by measuring and plotting the intensity of these specific bands.For quantitative analysis of the distribution within microspheres,Matlab software was used to transform the map file into a 3D matrix and the matrix values specific for the drug and excipient were extracted.Comparison of the normalized SR-FTIR maps of PLGA and Exenatide indicated that PLGA was uniformly distributed,while Exenatide was relatively non-uniformly distributed in the microspheres.In conclusion,SR-FTIR is a rapid,nondestructive and sensitive detection technology to provide the distribution of chemical constituents and functional groups in microparticles and microspheres. | Manli Wang Xiaolong Lu Xianzhen Yin Yajun Tong Weiwei Peng Li Wu Haiyan Li Yan Yang Jingkai Gu Tiqiao Xiao Min Chen Jiwen Zhang | 2015 | Acta Pharmaceutica Sinica B2015，5，3： | 5 |
| 6 | Mizoribine versus mycophenolate mofetil or intravenous cyclophosphamide for induction treatment of active lupus nephritis显示文摘 | Feng Xuebing Gu Fei Chen Weiwei Liu Yan Wei Hua Liu Lin Yin Songlou Da Zhanyun Sun Lingyun | 2014 | Chinese Medical Journal2014，，21： | 5 |
| 7 | Label-free fiber nanograting sensor for real-time in situ early monitoring of cellular apoptosis显示文摘The achievement of functional nanomodules for subcellular label-free measurement has long been pursued in order to fully understand cellular functions.Here,a compact label-free nanosensor based on a fiber taper and zinc oxide nanogratings is designed and applied for the early monitoring of apoptosis in individual living cells.Because of its nanoscale dimensions,mechanical flexibility,and minimal cytotoxicity to cells,the sensing module can be loaded in cells for long term in situ tracking with high sensitivity.A gradual increase in the nuclear refractive index during the apoptosis process is observed,revealing the increase in molecular density and the decrease in cell volume.The strategy used in our study not only contributes to the understanding of internal environmental variations during cellular apoptosis but also provides a new platform for nonfluorescent fiber devices for investigation of cellular events and understanding fundamental cell biochemical engineering. | Danran Li Nina Wang Tianyang Zhang Guangxing Wu Yifeng Xiong Qianqian Du Yunfei Tian Weiwei Zhao Jiandong Ye Shulin Gu Yanqing Lu Dechen Jiang Fei Xu | 2022 | Advanced Photonics2022，4，1： | 5 |
| 8 | Gualoupi (Pericarpium Trichosanthis) injection in combination with convention therapy for the treatment of angina pectoris: a Meta-analysis显示文摘OBJECTIVE: To use a Meta-analysis to review the efficacy and safety of Gualoupi(Pericarpium Trichosanthis) injection(PTI) in the treatment of angina pectoris.METHODS: We searched the available literature up to January 2015 using Chinese National Knowledge Infrastructure(CNKI), Chinese Scientific Journal Database(VIP), the Wanfang database, Pub Med and other English language databases to identify randomized controlled trials of PTI for the treatment of angina pectoris. Two reviewers independently retrieved and extracted the information. Software Review Manager 5.3 was used for statistics analysis.RESULTS: Fourteen studies involving 1621 patients were identified. Compared with conventional therapy alone or conventional therapy plus other Traditional Chinese Injections(TCMIs), PTI plus conventional therapy significantly improved clinical efficacy [odds ratio(OR) = 3.56, 95% confidence interval(CI)(2.65, 4.77)](based on 14 studies), electrocardiograph efficacy [OR = 3.20, 95% CI(2.26, 4.51)](based on 7 studies), and efficacy for Traditional Chinese Medicine Syndromes [OR = 3.13, 95% CI(1.43, 6.89)](based on 3 studies). Moreover, compared with conventional therapy alone or conventional therapy plus other TCMIs, PTI plus conventional therapy significantly decreased the levels of plasma viscosity [mean difference(MD) =- 0.47,95% CI(-0.76,-0.17)](based on 3 studies), and plasma low-density lipoprotein [MD =-0.94, 95%CI(-1.57,-0.30)](based on 3 studies). Eleven studies reported some mild adverse reactions, and no seriousadversedrugreactionswereobserved.CONCLUSION: PTI was found to be effective and safe for the treatment of angina pectoris. This study had certain limitations; thus, more rigorously designed, multi-center, randomized controlled trials in larger populations should be performed to support this observation. | Zhu Yao Xia Wei Liu Weiwei Xu Chongbai Gu Ning | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 4 |
| 9 | Uterine artery embolization combined with ultrasound-guided dilation and 5–8-year follow-up study显示文摘Objective: To evaluate the efficacy and safety of uterine artery embolization(UAE) combined with dilation and curettage(D&C) using ultrasound as a treatment for cesarean scar pregnancy(CSP) and assess its effect on ovarian and reproductive function.Methods: A total of 54 patients with uterine CSP between January 2011 and December 2015 were included in this retrospective study. The patients were treated with UAE combined with D&C using ultrasound for the treatment of CSP and followed up for 5–8 years. Their medical records, medical histories, clinical manifestations, treatment courses, and treatment results were analyzed.Results: The 54 patients were initially treated without severe complications. β-Human chorionic gonadotropin(β-hCG) normalization took 36.11 ± 10.73 days(range, 25–84 days), length of hospitalization was 6.6 ± 1.5 days(range, 4–10 days), and total blood loss was 18.48 ± 8.41 mL(range, 5–33 mL). All patients resumed normal menstruation after 33.48 ± 8.71 days(range, 26–70 days). At the 5–8-year follow-up after UAE combined with D&C by ultrasound for the treatment of uterine CSP, the menstrual volume in 32(59.3%) patients decreased versus before the operation. Compared with pretreatment, the menstrual cycle was prolonged in two(3.7%) cases,shortened in 10(18.5%) cases, irregular in one(1.9%) case, and unchanged in 39(72.2%) cases. Three patients conceived naturally and successfully gave birth to healthy children. Seven(12.96%) patients with accidental natural pregnancies chose induced abortion with no significant change in their sex lives.Conclusion: UAE combined with D&C using ultrasound for the treatment of uterine CSP is safe and effective and may not affect the fertility of patients aged <40 years. However, menstrual volume may be reduced in some patients. | Zhuxin Gu Pengfei Jia Ziyang Gao Weiwei Gu Hui Zhao Suming Zhao | 2022 | Journal of Interventional Medicine2022，5，3： | 2 |
| 10 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 11 | Double-side fabrication process and millimeter waveresponse of intrinsic Josephson junctions显示文摘We adopted double-side fabrication process to prepare intrinsic Josephson junctions (IJJs) based on Bi2Sr2CaCu2O8+x (BSCCO) single crystals. Using crystal cleavage and double-side argon ion milling, we have successfully fabricated very uniform IJJs with the thickness of single crystal slice less than 200 nm. Using quasi-optical system, the response of the IJJs to millimeter wave radiation was studied. With applied magnetic field perpendicular to a-b plane, we have observed Shapiro steps under millimeter wave radiation, and the Josephson oscillation of each junction was phase-locking. | WU JingBo YI DongChao GU ZhengHao KANG Lin XU WeiWei CHEN Jian WU PeiHeng | 2009 | Chinese Science Bulletin2009，54，5： | 2 |
| 12 | Integrated Analysis of Long Noncoding RNA and Coding RNA Expression in Esophageal Squamous Cell Carcinoma显示文摘 | Wei Cao Wei Wu Fachun Shi Xiaobing Chen Lihua Wu Ke Yang Fu Tian Minghui Zhu Guoyong Chen WeiWei Wang Fred G. Biddle Jianqin Gu Soraya E. Gutierrez | 2013 | International Journal of Genomics2013，，： | 1 |
| 13 | Adult rat bone marrow stromal cells differentiate into Schwann cell-like cells in vitro显示文摘 | WeiWei Lin Xue Chen XiaoDong Wang Jie Liu XiaoSong Gu | 2008 | In Vitro Cellular & Developmental Biology - Animal (-)2008，，1： | 1 |
| 14 | Polymorphisms of the vascular endothelial growth factor A gene and susceptibility to sporadic brain arteriovenous malformation in a Chinese population显示文摘 | Hongyan Chen Yuxiang Gu Wenting Wu Dan Chen Peiliang Li Weiwei Fan Daru Lu Fan Zhao Nidan Qiao Huijia Qiu Chaowei Fu Ying Mao Yao Zhao | 2010 | Journal of Clinical Neuroscience2010，，4： | 1 |
| 15 | Quantitative assessment of the association between three polymorphisms in FAS and FASL gene and breast cancer risk显示文摘 | Zexing Wang Jun Gu Weiwei Nie Jing Xu Guichun Huang Xiaoxiang Guan | 2014 | Tumor Biology2014，，： | 1 |
| 16 | Predicting Tie Strength of Chinese Guanxi by Using Big Data of Social Networks显示文摘This paper poses a question:How many types of social relations can be categorized in the Chinese context?In social networks,the calculation of tie strength can better represent the degree of intimacy of the relationship between nodes,rather than just indicating whether the link exists or not.Previou research suggests that Granovetter measures tie strength so as to distinguish strong ties from weak ties,and the Dunbar circle theory may offer a plausible approach to calculating 5 types of relations according to interaction frequency via unsupervised learning(e.g.,clustering interactive data between users in Facebook and Twitter).In this paper,we differentiate the layers of an ego-centered network by measuring the different dimensions of user's online interaction data based on the Dunbar circle theory.To label the types of Chinese guanxi,we conduct a survey to collect the ground truth from the real world and link this survey data to big data collected from a widely used social network platform in China.After repeating the Dunbar experiments,we modify our computing methods and indicators computed from big data in order to have a model best fit for the ground truth.At the same time,a comprehensive set of effective predictors are selected to have a dialogue with existing theories of tie strength.Eventually,by combining Guanxi theory with Dunbar circle studies,four types of guanxi are found to represent a four-layer model of a Chinese ego-centered network. | Xin Gao Jar-Der Luo Kunhao Yang Xiaoming Fu Loring Liu Weiwei Gu | 2020 | Journal of Social Computing2020，1，1： | 1 |
| 17 | Hydrazine bisborane as a promising material for chemical hydrogen storage 显示文摘 | SUN Weiwei GU Qinfen GUO Yanhui | 2011 | Fuel & Energy Abstracts2011，36，13： | 1 |
| 18 | Learning Universal Network Representation via Link Prediction by Graph Convolutional Neural Network显示文摘Network representation learning algorithms,which aim at automatically encoding graphs into low-dimensional vector representations with a variety of node similarity definitions,have a wide range of downstream applications.Most existing methods either have low accuracies in downstream tasks or a very limited application field,such as article classification in citation networks.In this paper,we propose a novel network representation method,named Link Prediction based Network Representation(LPNR),which generalizes the latest graph neural network and optimizes a carefully designed objective function that preserves linkage structures.LPNR can not only learn meaningful node representations that achieve competitive accuracy in node centrality measurement and community detection but also achieve high accuracy in the link prediction task.Experiments prove the effectiveness of LPNR on three real-world networks.With the mini-batch and fixed sampling strategy,LPNR can learn the embedding of large graphs in a few hours. | Weiwei Gu Fei Gao Ruiqi Li Jiang Zhang | 2021 | Journal of Social Computing2021，2，1： | 1 |
| 19 | Poly(ADP-ribose) polymerases regulate cell division and development in Arabidopsis roots显示文摘Root organogenesis involves cell division,differentiation and expansion. The molecular mechanisms regulating root development are not fully understood.In this study, we identified poly(adenosine diphosphate(ADP)-ribose) polymerases(PARPs) as new players in root development. PARP catalyzes poly(ADP-ribosyl)ation of proteins by repeatedly adding ADP-ribose units onto proteins using nicotinamide adenine dinucleotide(NADt)as the donor. We found that inhibition of PARP activities by3-aminobenzomide(3-AB) increased the growth rates of both primary and lateral roots, leading to a more developed root system. The double mutant of Arabidopsis PARPs, parp1parp2, showed more rapid primary and lateral root growth. Cyclin genes regulating G1-to-S and G2-to-Mtransition were up-regulated upon treatment by 3-AB.The proportion of 2C cells increased while cells with higher DNA ploidy declined in the roots of treated plants, resulting in an enlarged root meristematic zone. The expression level of PARP2 was very low in the meristematic zone but high in the maturation zone, consistent with a role of PARP in inhibiting mitosis and promoting cell differentiation. Our results suggest that PARPs play an important role in root development by negatively regulating root cell division. | Caifeng Liu Qiao Wu Weiwei Liu Zongyin Gu Wenjing Wang Ping Xu Hong Ma Xiaochun Ge | 2017 | Journal of Integrative Plant Biology2017，59，7： | 1 |
| 20 | Astragaloside IV attenuates glycated albumin-induced epithelial-to-mesenchymal transition by inhibiting oxidative stress in renal proximal tubular cells显示文摘 | Weiwei Qi Jianying Niu Qiaojing Qin Zhongdong Qiao Yong Gu | 2014 | Cell Stress and Chaperones2014，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员