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| 1 | Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis显示文摘精子发生在双 spermatogonial 干细胞(SSC ) 哪个生产 haploid 精子期间是一个区别过程。这个高度专业化的过程精确在 transcriptional, posttranscriptional,和翻译层次被控制。这里,我们报导那 N 6-methyladenosine (m 6 一) ,调整基因表示的一个 epitranscriptomic 标记,在精子发生期间起必要作用。我们现在的全面 m 6 从五个发展阶段的老鼠 spermatogenic 房间的 mRNA methylomes:无差别的 spermatogonia,类型 A 1 spermatogonia, preleptotene spermatocytes, pachytene/diplotene spermatocytes,和圆 spermatids。m 6 有 Vasa-Cre 的 RNA methyltransferase Mettl3 或 Mettl14 引起 m 6 SSC 的 A 和弄空。m 6 为 SSC 增长 / 区别被要求的抄本的一个弄空 dysregulates 翻译。在有 Stra8-GFPCre 的先进细菌房间的 Mettl3 和 Mettl14 的联合删除破坏精子形式,而有在先进细菌房间的 Mettl3 或 Mettl14 的单个删除的老鼠显示出正常精子发生。从双异种老鼠展览的 spermatids 损害了为精子形式是必要的 haploid 特定的基因的翻译。这研究加亮 mRNA m 6 在 germline 开发的修正,潜在地保证在精子发生的不同阶段协调了翻译。 | Zhen Lin Phillip J Hsu Xudong Xing Jianhuo Fang Zhike Lu Qin Zou Ke-Jia Zhang Xiao Zhang Yuchuan Zhou Teng Zhang Youcheng Zhang Wanlu Song Guifang Jia Xuerui Yang Chuan He Ming-Han Tong | 2017 | Cell Research2017，27，10： | 61 |
| 2 | 2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma显示文摘The incidence of papillary thyroid carcinoma(PTC)has exponentially increased in recent years.Papillary thyroid microcarcinoma(PTMC)accounts for the majority of the reported cases of PTC.The debates and crucial issues in PTMC management have received researchers'attention.To further improve the clinical management of PTMC in China, | Ming Gao Minghua Ge Qinghai Ji Ruochuan Cheng Hankui Lu Haixia Guan Li Gao Zhuming Guo Tao Huang Xiaoming Huang Xiaoming Li Yansong Lin Qinjiang Liu Xin Ni Yi Pan Jianwu Qin Zhongyan Shan Hui Sun Xudong Wang Zhengang Xu Yang Yu Daiwei Zhao Naisong Zhang ShengZhang Ying Zheng Jingqiang Zhu Dapeng Li Xiangqian Zheng 无 | 2017 | Cancer Biology & Medicine2017，14，3： | 23 |
| 3 | A Strigolactone Biosynthesis Gene Contributed to the Green Revolution in Rice显示文摘Plant architecture is a complex agronomic trait and a major factor of crop yield,which is affected by several important hormones.Strigolactones(SLs)are identified as a new class hormoneinhibiting branching in many plant species and have been shown to be involved in various developmental processes.Genetical and chemical modulation of the SL pathway is recognized as a promising approach to modify plant architecture.However,whether and how the genes involved in the SL pathway could be utilized in breeding still remain elusive.Here,we demonstrate that a partial loss-of-function allele of the SL biosynthesis gene,HIGH TILLERING AND DWARF 1/DWARF17(HTD1/D17),which encodes CAROTENOID CLEAVAGE DIOXYGENASE 7(CCD7),increases tiller number and improves grain yield in rice.We found that the HTD1 gene had been widely utilized and co-selected with Semidwarf 1(SD1),both contributing to the improvement of plant architecture in modern rice varieties since the Green Revolution in the 1960s.Understanding how phytohormone pathway genes regulate plant architecture and how they have been utilized and selected in breeding will lay the foundation for developing the rational approaches toward improving crop yield. | Yuexing Wang Lianguang Shang Hong Yu Longjun Zeng Jiang Hu Shen Ni Yuchun Rao Sanfeng Li Jinfang Chu Xiangbing Meng Lei Wang Ping Hu Jijun Yan Shujing Kang Minghao Qu Hai Lin Tao Wang Quan Wang Xingming Hu Hongqi Chen Bing Wang Zhenyu Gao Longbiao Guo Dali Zeng Xudong Zhu Guosheng Xiong Jiayang Li Qian Qian | 2020 | Molecular Plant2020，13，6： | 23 |
| 4 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 5 | Island partition of the distribution system with distributed generation显示文摘In this paper, a novel optimum island partition model based on Tree Knapsack Problem (TKP) is presented for the distribution system integrated with distributed generation (DG), and a Depth-first Dynamic Programming Algorithm (DPA) is used to solve this model. With the considerations of the load priority, controlled/uncontrolled loads, and the constraints of power balance, voltage and equipment capacity, the model can meet the practical engineering requirements very well. The island partition problem of the distribution system integrated with multiple DGs is first decomposed into multiple TKPs, each of which is solved by DPA respectively. Then, the initial optimum island partition scheme is gained through an island combination procedure, and the final island partition scheme is obtained after feasibility checking and adjustment. Since the algorithm proposed owns the advantages of strong theoretical foundation and low computational complexity, it can find the approximate optimal solution within a limited time. The results of examples demonstrate the validity of the new model and algorithm. | WANG XuDong & LIN JiKeng* Key laboratory of Power System Simulation and Control of Ministry of Education, Tianjin University, Tianjin 300072, China | 2010 | Science China(Technological Sciences)2010，53，11： | 21 |
| 6 | Model and Algorithm for the Optimal Controlled Partitioning of Power Systems显示文摘解列是电力系统在故障时结构完整性得不到保证的情况下分裂为2个或多个孤立稳定运行子系统的过程或操作。及时恰当的主动解列操作将能有效地避免因保护连锁动作使得电力系统被动解列而崩溃所造成的巨额经济损失。结合图论中的相关概念和输电网最优解列的物理过程,建立电力系统最优主动解列断面选择问题的完整数学模型,并基于含连通图约束的背包问题(connected graph constrained knapsack problem,CGKP)及其求解算法提出“搜索+调整”的2阶段求解方法。为降低问题的复杂性,将完整数学模型分解成图的最优平衡分割问题和基于优化潮流的调节问题,并分2个阶段分别求解。其中,图的最优平衡分割问题又被分解成多个CGKP,利用基于含CGKP的图分割方法进行求解。所提出的主动解列策略具有较强理论基础,计算复杂度低,算例的计算结果证明了该模型及算法的正确性和有效性。 | LIN Jikeng LI Shengwen WU Peng WANG Xudong SHAO Guanghui XU Xingwei MA Xin | 2012 | 中国电机工程学报2012，32，13： | 15 |
| 7 | Laser performance of the SG-Ⅲ laser facility显示文摘SG-Ⅲ laser facility is now the largest laser driver for inertial confinement fusion research in China. The whole laser facility can deliver 180 kJ energy and 60 TW power ultraviolet laser onto target, with power balance better than 10%.We review the laser system and introduce the SG-Ⅲ laser performance here. | Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Jingqin Su Kuixing Zheng Xiaodong Yuan Hai Zhou Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Xuewei Deng | 2016 | High Power Laser Science and Engineering2016，4，3： | 13 |
| 8 | Laser performance upgrade for precise ICF experiment in SG-Ⅲ laser facility显示文摘The SG-Ⅲlaser facility(SG-Ⅲ)is the largest laser driver for inertial confinement fusion(ICF)researches in China,which has 48 beamlines and can deliver 180 kJ ultraviolet laser energy in 3 ns.In order to meet the requirements of precise physics experiments,some new functionalities need to be added to SG-Ⅲand some intrinsic laser performances need upgrade.So at the end of SG-Ⅲ's engineering construction,the 2-year laser performance upgrade project started.This paper will introduce the newly added functionalities and the latest laser performance of SG-Ⅲ.With these function extensions and performance upgrade,SG-Ⅲis now fully prepared for precise ICF experiments and solidly paves the way towards fusion ignition. | Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Xiaodong Yuan Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Rui Zhang Fang Wang Huaiting Jia Xuewei Deng | 2017 | Matter and Radiation at Extremes2017，2，5： | 13 |
| 9 | Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo显示文摘 | Yanjing Song Chuan Tong Yao Wang Yunhe Gao Hanren Dai Yelei Guo Xudong Zhao Yi Wang Zizheng Wang Weidong Han Lin Chen | 2018 | Protein & Cell2018，9，10： | 11 |
| 10 | Prognostic Factors Predicting the Postoperative Survival Period Following Treatment for Primary Retroperitoneal Liposarcoma显示文摘 | Xudong Zhao Peiyu Li Xiaohui Huang Lin Chen Na Liu Yaoguang She | 2015 | Chinese Medical Journal2015，，1： | 9 |
| 11 | Attenuated Listeria monocytogenes as a cancer vaccine vector for the delivery of CD24, a biomarker for hepatic cancer stem cells显示文摘稀释 Listeria monocytogenes (LM ) 是为癌症疫苗的交货的有希望的候选人向量。在由介绍抗原的房间的吞噬作用以后,这个细菌刺激主要 histocompatibility 建筑群(MHC ) 我和 MHC-II 小径并且导致抗原特定的 T 淋巴细胞的增长。包含复制缺乏的 LM 种类 Δ 的基因修正的新策略; dalΔ dat (Lmdd ) 被开发了表示并且藏匿人的 CD24 蛋白质。CD24 是仔细与 hepatocellular 癌(HCC ) 的 apoptosis,转移和复发被联系的肝的癌症干细胞 biomarker。在在老鼠的静脉内的管理以后, Lmdd-CD24 首先在怒气和肝被散布并且没引起严重机关损害。Lmdd-CD24 有效地增加了干扰素(IFN ) 的数字 -γ-producing CD8 + T 房间和 IFN-γ分泌物。Lmdd-CD24 也提高了 IL-4- 和 IL-10-producing T 助手 2 房间的数字。Lmdd-CD24 疫苗的功效进一步对 Hepa1-6-CD24 肿瘤被调查,它腹股沟地被接种进老鼠。Lmdd-CD24 显著地在老鼠减少了肿瘤尺寸并且增加了他们的幸存。尤其是, T 规章的房间(Treg ) 的减小数并且特定的 CD8 +T 房间活动的改进在渗入肿瘤的淋巴细胞(TIL ) 被观察。这些结果对 HCC 建议 Lmdd-CD24 疫苗的一个潜在的应用程序。 | Yu Yang Jiajie Hou Zhe Lin Han Zhuo DianyuChen Xudong Zhang Yun Chen Beicheng Sun | 2014 | Cellular & Molecular Immunology2014，11，2： | 9 |
| 12 | A comparative study of the osteogenic performance between the hierarchical micro/submicro-textured 3D-printed Ti6Al4V surface and the SLA surface显示文摘Three-dimensional(3D)printed titanium and its alloys have broad application prospect in the field of biomedical implant materials,although the biological performance of the original surface should be improved.Learning from the development experience of conventional titanium implants,to construct a hierarchical hybrid topological surface is the future direction of efforts.Since the original 3D-printed(3D hereafter)Ti6Al4V surface inherently has micron-scale features,in the present study,we introduced submicron-scale pits on the original surface by acid etching to obtain a hierarchical micro/submicro-textured surface.The characteristic and biological performance of the 3D-printed and acid-etched(3DA hereafter)surface were evaluated in vitro and in vivo,compared with the conventional sandblasted,large-grit,acid-etched(SLA hereafter)surface.Our results suggested the adhesion,proliferation and osteogenic differentiation of bone marrow derived mesenchymal stromal cells(BMSCs),as well as the in vivo osseointegration on 3DA surfaces were significantly improved.However,the overall osteogenic performance of the 3DA surface was not as good as the conventional SLA surface. | Jinkai Zhanga Jiaqiang Liu Chengtao Wang Fengshan Chen Xudong Wang Kaili Lin | 2020 | Bioactive Materials2020，5，1： | 8 |
| 13 | Advanced hydrogels for the repair of cartilage defects and regeneration显示文摘Cartilage defects are one of the most common symptoms of osteoarthritis(OA),a degenerative disease that affects millions of people world-wide and places a significant socio-economic burden on society.Hydrogels,which are a class of biomaterials that are elastic,and display smooth surfaces while exhibiting high water content,are promising candidates for cartilage regeneration.In recent years,various kinds of hydrogels have been developed and applied for the repair of cartilage defects in vitro or in vivo,some of which are hopeful to enter clinical trials.In this review,recent research findings and developments of hydrogels for cartilage defects repair are summarized.We discuss the principle of cartilage regeneration,and outline the requirements that have to be fulfilled for the deployment of hydrogels for medical applications.We also highlight the development of advanced hydrogels with tailored properties for different kinds of cartilage defects to meet the requirements of cartilage tissue engineering and precision medicine. | Wei Wei Yuanzhu Ma Xudong Yao Wenyan Zhou Xiaozhao Wang Chenglin Li Junxin Lin Qiulin He Sebastian Leptihn Hongwei Ouyang | 2021 | Bioactive Materials2021，6，4： | 8 |
| 14 | Investigation and Improvement of the Staggered Labyrinth Seal显示文摘Recent studies on staggered labyrinth seals have focused on the effects of different parameters,such as the pressure ratio and rotational speed on the leakage flow rate.However,few investigations pay sufficient attention to flow details and the sealing mechanism,which would be of practical importance in designing seals having higher performance.This paper establishes a theoretical model to study the seal mechanism,thus revealing that leakage is determined by the pressure ratio and geometric structure.Numerical simulation is implemented to illustrate details of the flow field within the seal structure.Viscous dissipation is used to quantitatively investigate the contribution that each location makes to the seal performance,revealing that orifices and stagnation points are the most important positions in the seal structure,generating the most dissipation.The orifice is carefully studied by using the theoretical model.Experiments for different pressure ratios are conducted and the results match well with those of the theoretical model and numerical simulation,verifying the theoretical model and analysis of the seal mechanism.Three new designs,based on a good understanding of the seal mechanism,are presented,with one reducing leakage by 24.5%. | LIN Zhirong WANG Xudong YUAN Xin SHIBUKAWA Naoki NOGUCHI Taro | 2015 | Chinese Journal of Mechanical Engineering2015，28，2： | 7 |
| 15 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 16 | Introduction to Cloud Manufacturing显示文摘Cloud manufacturing is a new, networked and intelligent manufacturing model that is service-oriented, knowledge based, high performance, and energy efficient. In this model, state-of-the-art technologies such as informatized manufacturing, cloud computing, Internet of Things, semantic Web, and high-performance computing are integrated in order to provide secure, reliable, and high quality on-demand services at low prices for those involved in the whole manufacturing lifecycle. As an important part of cloud manufacturing, cloud simulation technology based on the COSIM-CSP platform has primarily been applied in the design of a multidisciplinary virtual prototype of a flight vehicle. This lays the foundation for further research into cloud manufacturing. | Li Bohu Zhang Lin Chai Xudong | 2010 | ZTE Communications2010，8，4： | 6 |
| 17 | Microstructure and mechanical properties of Al-Mg-Mn alloy with erbium显示文摘The effect of trace element Er on the microstructure and properties of Al-6Mg-0.7Mn-0.1Cr-0.15Ti alloy was investigated. The results show that the ultimate room-temperature and high-temperature strength sof the alloy have not increased obviously with the addition of erbium, but the uniform elongation of alloys decreases from 9% and 27.5% to 5.5% and 22.5%, respectively. The reason is that the addition of Er will first react with Ti, Cr to form Al20Ti2Er, Al8Cr4Er phases. The precipitation strengthening makes up the weakening of grain refinement strengthening. During deformation, the primary Al(TiCr)Er and Al3Er particles fracture first and act as the microcrack sources because of the stress concentration. | Wang, Xudong Lin, Shuangping Yang, Junjun Tang, Zhenlei Nie, Zuoren | 2012 | Rare Metals2012，31，3： | 6 |
| 18 | Large-area high quality PtSe2 thin film with versatile polarity显示文摘Two-dimensional(2D)materials have attracted increasing attention for their outstanding structural and electrical properties.However,for mass-production of field effect transistors(FETs)and potential applications in integrated circuits,large-area and uniform 2D thin films with high mobility,large on-off ratio,and desired polarity are needed to synthesize firstly.Here,a transfer-free growth method for platinum diselenide(PtSe2)films has been developed.The PtSe2 films have been synthesized with various thicknesses in centimeter-sized scale.Typical FET made from a few layer PtSe2 show p-type unipolar,with a high field-effect hole mobility of 6.2 cm^(2) V^(−1) s^(−1) and an on-off ratio of 5×10^(3).The versatile semimetal-unipolar-ambipolar transition in synthesized PtSe2 films is also firstly observed as the thickness thinning.This work realizes the large-scale preparation of PtSe2 with prominent electrical properties and provides a new strategy for polarity's modulation. | Wei Jiang Xudong Wang Yan Chen Guangjian Wu Kun Ba Ningning Xuan Yangye Sun Peng Gong Jingxian Bao Hong Shen Tie Lin Xiangjian Meng Jianlu Wang Zhengzong Sun | 2019 | InfoMat2019，1，2： | 5 |
| 19 | The synergistic effect of 3D-printed microscale roughness surface and nanoscale feature on enhancing osteogenic differentiation and rapid osseointegration显示文摘Personalized precision therapy and rapid osseointegration are the main development directions of dental implants.3 D printing is a vital advanced manufacturing technology for personalized precision therapy.However,the osteogenesis of the 3 D printed Ti6 Al4 V implants is unsatisfactory.From the bionic perspective,the hierarchical micro/nano-topography can mimic the microenvironment of the multilevel structure of natural bone tissue and may endow the implant surface with superior bioactivity.In the present study,the hierarchical micro/nano-topography was successfully fabricated by construction the nanoscale feature on 3 D printed microscale roughness surface of 3 D-printed Ti6 Al4 V implants by alkali-heat treatment and hydrothermal treatment.Then the cell biological responses in vitro and osseointegration performance in vivo were systematically evaluated.The hierarchical micro/nano-topography evidently increased the roughness,improved the hydrophilicity and accelerated the hydroxyapatite deposition and mineralization,which significantly enhanced the adhesion,differentiation and extracellular matrix mineralization of bone marrow derived mesenchymal stromal cells(BMSCs).Most importantly,the hierarchical micro/nano-topography on 3 D-printed implants facilitated the new bone formation and rapid osseointegration in vivo.Our study suggested that 3 D-printed implant with micro/nano-topography may be a promising candidate to be applied in orthopedic field to meet the need of customized therapy and rapid osseointegration. | Hui Wang Jiaqiang Liu Chengtao Wang Steve Guofang Shen Xudong Wang Kaili Lin | 2021 | Journal of Materials Science & Technology2021，，4： | 5 |
| 20 | Performability analysis of avionics system with multilayer HM/FM using stochastic Petri nets显示文摘The integrated modular avionics (IMA) architecture is an open standard in avionics industry, in which the number of functionalities implemented by software is greater than ever before. In the IMA architecture, the reliability of the avionics system is highly affected by the software applications. In order to enhance the fault tolerance feature with regard to software application failures, many industrial standards propose a layered health monitoring/fault management (HM/FM) scheme to periodically check the health status of software application processes and recover the malfunctioning software process whenever an error is located. In this paper, we make an analytical study of the HM/FM system for avionics application software. We use the stochastic Petri nets (SPN) to build a formal model of each component and present a method to combine the components together to form a complete system model with respect to three interlayer query strategies. We further investigate the effectiveness of these strategies in an illustrative system. | Wan Jianxiong Xiang Xudong Bai Xiaoying Lin Chuang Kong Xiangzhen Li Jianxiang | 2013 | Chinese Journal of Aeronautics2013，26，2： | 4 |
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