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| 1 | Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury显示文摘The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan,Hubei province,and rapidly spread to many provinces in China as well as other countries.Here we report the epidemiological,clinical,laboratory,and radiological characteristics,as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen,China.All 12 cases of the 2019-nCoV-infected patients developed pneumonia and half of them developed acute respiratory distress syndrome (ARDS).The most common laboratory abnormalities were hypoalbuminemia,lymphopenia,decreased percentage of lymphocytes (LYM) and neutrophils (NEU),elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH),and decreased CD8 count.The viral load of 2019-nCoV detected from patient respiratory tracts was positively linked to lung disease severity.ALB,LYM,LYM (%),LDH,NEU (%),and CRP were highly correlated to the acute lung injury.Age,viral load,lung injury score,and blood biochemistry indexes,albumin (ALB),CRP,LDH,LYM (%),LYM,and NEU (%),may be predictors of disease severity.Moreover,the Angiotensin Ⅱlevel in the plasma sample from 2019-nCoV infected patients was markedly elevated and linearly associated to viral load and lung injury.Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection. | Yingxia Liu Yang Yang Cong Zhang Fengming Huang Fuxiang Wang Jing Yuan Zhaoqin Wang Jinxiu Li Jianming Li Cheng Feng Zheng Zhang Lifei Wang Ling Peng Li Chen Yuhao Qin Dandan Zhao Shuguang Tan Lu Yin Jun Xu Congzhao Zhou Chengyu Jiang Lei Liu | 2020 | Science China(Life Sciences)2020，63，3： | 157 |
| 2 | Synthesis of hydrophobic carbon nanotubes/reduced graphene oxide composite films by flash light irradiation显示文摘 | Kai Wang Jinbo Pang Liwei Li Shengzhe Zhou Yuhao Li Tiezhu Zhang | 2018 | Frontiers of Chemical Science and Engineering2018，12，3： | 10 |
| 3 | Autonomous driving: cognitive construction and situation understanding显示文摘Autonomous vehicle is a kind of typical complex artificial intelligence system. In current research of autonomous driving, the most widely adopted technique is to use a basic framework of serial information processing and computations, which consists of four modules: perception, planning, decision-making, and control. However, this framework based on data-driven computing performs low computational efficiency,poor environmental understanding and self-learning ability. A neglected problem has long been how to understand and process environmental perception data from the sensors referring to the cognitive psychology level of the human driving process. The key to solving this problem is to construct a computing model with selective attention and self-learning ability for autonomous driving, which is supposed to possess the mechanism of memorizing, inferring and experiential updating, enabling it to cope with traffic scenarios with high noise, dynamic, and randomness. In addition, for the process of understanding traffic scenes,the efficiency of event-related mechanism is more significant than single-attribute scenario perception data.Therefore, an effective self-driving method should not be confined to the traditional computing framework of‘perception, planning, decision-making, and control’. It is necessary to explore a basic computing framework that conforms to human driver’s attention, reasoning, learning, and decision-making mechanism with regard to traffic scenarios and build an autonomous system inspired by biological intelligence. In this article, we review the basic methods and main progress in current data-driven autonomous driving technologies, deeply analyze the limitations and major problems faced by related algorithms. Then, combined with authors’ research, this study discusses how to implement a basic cognitive computing framework of self-driving with selective attention and an event-driven mechanism from the basic viewpoint of cognitive science. It further describes how to use multi-sensor and graph data with semantic information(such as traffic maps and a spatial correlation of events) to realize the associative representations of objects and drivable areas, as well as the intuitive reasoning method applied to understanding the situations in different traffic scenarios. The computing framework of autonomous driving based on a selective attention mechanism and intuitive reasoning discussed in this study can adapt to a more complex, open, and dynamic traffic environment. | Shitao CHEN Zhiqiang JIAN Yuhao HUANG Yu CHEN Zhuoli ZHOU Nanning ZHENG | 2019 | Science China(Information Sciences)2019，62，8： | 6 |
| 4 | Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury显示文摘A recent outbreak of pneumonia in Wuhan,China was found to be caused by a 2019 novel coronavirus(2019-nCoV or SARS-CoV-2 or HCoV-19).We previously reported the clinical features of 12 patients with2019-n Co V infections in Shenzhen,China.To further understand the pathogenesis of COVID-19 and find better ways to monitor and treat the disease caused by 2019-n Co V,we measured the levels of 48 cytokines in the blood plasma of those 12 COVID-19 patients.Thirty-eight out of the 48 measured cytokines in the plasma of 2019-n Co V-infected patients were significantly elevated compared to healthy individuals.Seventeen cytokines were linked to 2019-nCoV loads.Fifteen cytokines,namely M-CSF,IL-10,IFN-α2,IL-17,IL-4,IP-10,IL-7,IL-1 ra,G-CSF,IL-12,IFN-γ,IL-1α,IL-2,HGF and PDGF-BB,were strongly associated with the lung-injury Murray score and could be used to predict the disease severity of2019-n Co V infections by calculating the area under the curve of the receiver-operating characteristics.Our results suggest that 2019-nCoV infections trigger extensive changes in a wide array of cytokines,some of which could be potential biomarkers of disease severity of 2019-n Co V infections.These findings will likely improve our understanding of the immunopathologic mechanisms of this emerging disease.Our results also suggest that modulators of cytokine responses may play a therapeutic role in combating the disease once the functions of these elevated cytokines have been characterized. | Yingxia Liu Cong Zhang Fengming Huang Yang Yang Fuxiang Wang Jing Yuan Zheng Zhang Yuhao Qin Xiaoyun Li Dandan Zhao Shunwang Li Shuguang Tan Zhaoqin Wang Jinxiu Li Chenguang Shen Jianming Li Ling Peng Weibo Wu Mengli Cao Li Xing Zhixiang Xu Li Chen Congzhao Zhou William J Liu Lei Liu Chengyu Jiang | 2020 | National Science Review2020，7，6： | 6 |
| 5 | Survey of reefs based on Landsat 8 operational land imager(OLI)images in the Nansha Islands, South China Sea显示文摘A detailed survey of the reefs in the Nansha Islands' sea that are of strategic importance is conducive to their future development. In this study, a total of 50 Landsat 8 operational land imager(OLI) images were used to analyze the geological features and spectral characteristics of the Nansha reefs. The exposed islands/sandbanks,reef flats and sub-tidal reefs were identified with the near-infrared band, the red and green bands, and the blue band, respectively. Based on the relationships among various characteristics and bands illustrated in the OLI images, the maximum between-cluster variance threshold algorithm(OTSU method) and the mathematical morphology were employed to extract characteristic parameters of the spatial geometry of the reefs from top to bottom, which were subsequently operated by a series of post-processing methods such as vectorization,simplification and topological analysis. Among the 132 standalone reefs and 16 atolls that are identified in the study, four reefs have yet to be named in the Standard Names of Various Islands in the South China Sea and the website Nansha Islands Online(http://gffzzd4db47f6efa542b8h5vnwpb0nbk966xq6.ffgz.tsg.suse.edu.cn/). Another 24 ones are exposed to the atmosphere even during high tides. Taiping Island with an area of 0.57 km^2 represents the largest exposed geological feature. This study demonstrated the applicability of medium-resolution satellite images to derive the coral reef information effectively and thus provided information for the related departments that are responsible to manage the coast.An improved resolution of multispectral bands with the panchromatic band in higher spatial resolution(15 m for OLI image) is expected to provide an optimum satellite based approach to map marine habitats. | DUAN Yuewei LIU Yongxue LI Manchun ZHOU Minxi YANG Yuhao | 2016 | Acta Oceanologica Sinica2016，35，10： | 5 |
| 6 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 7 | Bistratal Au@Bi2S3 nanobones for excellent NIR-triggered/multimodal imaging-guided synergistic therapy for liver cancer显示文摘To fabricate a highly biocompatible nanoplatform enabling synergistic therapy and real-time imaging,novel Au@Bi2S3 core shell nanobones(NBs)(Au@Bi2S3 NBs)with Au nanorods as cores were synthesized.The combination of Au nanorods with Bi2S3 film made the Au@Bi2S3 NBs exhibit ultrahigh photothermal(PT)conversion efficiency,remarkable photoacoustic(PA)imaging and high computed tomography(CT)performance;these Au@Bi2S3 NBs thus are a promising nanotheranostic agent for PT/PA/CT imaging.Subsequently,poly(N-vinylpyrrolidone)-modified Au@Bi2S3 NBs(Au@Bi2S3-PVP NBs)were successfully loaded with the anticancer drug doxorubicin(DOX),and a satisfactory pH sensitive release profile was achieved,thus revealing the great potential of Au@Bi2S3-PVP NBs in chemotherapy as a drug carrier to deliver DOX into cancer cells.Both in vitro and in vivo investigations demonstrated that the Au@Bi2S3-PVP NBs possessed multiple desired features for cancer therapy,including extremely low toxicity,good biocompatibility,high drug loading ability,precise tumor targeting and effective accumulation.Highly efficient ablation of the human liver cancer cell HepG2 was achieved through Au@Bi2S3-PVP NB-mediated photothermal therapy(PTT).As both a contrast enhancement probe and therapeutic agent,Au@Bi2S3-PVP NBs provided outstanding NIR-triggered multi-modal PT/PA/CT imaging-guided PTT and effectively inhibited the growth of HepG2 liver cancer cells via synergistic chemo/PT therapy. | Ruizhuo Ouyang Penghui Cao Pengpeng Jia Hui Wang Tianyu Zong Chenyu Dai Jie Yuan Yuhao Li Dong Sun Ning Guo Yuqing Miao Shuang Zhou | 2021 | Bioactive Materials2021，6，2： | 5 |
| 8 | Measurement of γ detector backgrounds in the energy range of 3-8 MeV at Jinping underground laboratory for nuclear astrophysics显示文摘The astrophysical reaction rate of the charged-particleinduced reaction is dominated by the cross section within the Gamow window.The total cross section σ(E)of a chargedparticle-induced reaction is known to drops steeply with decreasing energy owing to the Coulomb barrier in the entrance channel: | YangPing Shen Jun Su WeiPing Liu Gang Lian Lin Gan LvHua Qiao ShengQuan Yan Yong Zhou Qian Yue Zhi Zeng QingDong Hu YuHao Mi Wei Zhao | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，10： | 5 |
| 9 | Fault tolerant multivehicle formation control framework with applications in multiquadrotor systems显示文摘Compared with the traditional monolithic systems,a group of vehicles operating cooperatively in a formation can achieve greater efficiency and capability [1,2].However,faults may occur more frequently in multivehicle formations because a large number of controllers,sensors,and com- munication equipment exist [3].Occasionally,a fault occurring in one vehicle of the formation may deteriorate the system performance or even cause catastrophic accidents.Thus,fault-tolerant formation control schemes are indispensable to achieve a reliable and safe operation. | Jiantao SHI Donghua ZHOU Yuhao YANG Jun SUN | 2018 | Science China(Information Sciences)2018，61，12： | 4 |
| 10 | Pushing the limits of microwave absorption capability of carbon fiber in fabric design based on genetic algorithm显示文摘The field of electromagnetic wave absorption(EWA)requires the adaptability,tenability,and multifunction of high-performance materials in the future.The design and preparation of EWA materials aiming at performance requirements is the latest research hotspot.Here,a performancedriven strategy for simultaneously coordinating different target performances was proposed to optimize the structure of the periodical long continuous carbon/glass fiber fabric(PCGF)materials through algorithm and simulation.The optimized structure of the PCGF not only improves the impedance matching,but also introduces the induced orientation effect for a high cooperative loss of conductivity,resonance,and periodic structure.The flexible PCGF shows a broad effective absorption bandwidth(EAB)of 32.7 GHz covering a part of the C-band and the whole X-,Ku-,K-,and Ka-bands with a thickness(d)of only 0.92 mm and a density of 5.6×10^(−4) kg·cm^(−3).This highly designable fabric is promising for the EWA practical application owing to integrating the characteristics of good flexibility,acid and alkali resistance,bending resistance,excellent mechanical properties,and easy large-scale preparation. | Yuhao LIU Xiaoxiao HUANG Xu YAN Long XIA Tao ZHANG Jiahao SUN Yanan LIU Yu ZHOU | 2023 | Journal of Advanced Ceramics2023，12，2： | 3 |
| 11 | A Knowledge-Enriched and Span-Based Network for Joint Entity and Relation Extraction显示文摘The joint extraction of entities and their relations from certain texts plays a significant role in most natural language processes.For entity and relation extraction in a specific domain,we propose a hybrid neural framework consisting of two parts:a span-based model and a graph-based model.The span-based model can tackle overlapping problems compared with BILOU methods,whereas the graph-based model treats relation prediction as graph classification.Our main contribution is to incorporate external lexical and syntactic knowledge of a specific domain,such as domain dictionaries and dependency structures from texts,into end-to-end neural models.We conducted extensive experiments on a Chinese military entity and relation extraction corpus.The results show that the proposed framework outperforms the baselines with better performance in terms of entity and relation prediction.The proposed method provides insight into problems with the joint extraction of entities and their relations. | Kun Ding Shanshan Liu Yuhao Zhang Hui Zhang Xiaoxiong Zhang Tongtong Wu Xiaolei Zhou | 2021 | Computers, Materials & Continua2021，，7： | 3 |
| 12 | A comprehensive analysis of the Bencao(herbal)small RNA Atlas reveals novel RNA therapeutics for treating human diseases显示文摘Cross-kingdom herbal mi RNA was first reported in 2012.Using a modified herbal extraction protocol,we obtained 73,677,287sequences by RNA-seq from 245 traditional Chinese Medicine(TCM),of which 20,758,257 were unique sequences.We constructed a Bencao(herbal)small RNA(s RNA)Atlas(http://gffzz4a3adbfa122d4a47h5vnwpb0nbk966xq6.ffgz.tsg.suse.edu.cn),annotated the sequences by sequence-based clustering,and created a nomenclature system for Bencao s RNAs.The profiles of 21,757 mi RNAs in the Atlas were highly consistent with those of plant mi RNAs in mi RBase.Using software tools,our results demonstrated that all human genes might be regulated by s RNAs from the Bencao s RNA Atlas,part of the predicted human target genes were experimentally validated,suggesting that Bencao s RNAs might be one of the main bioactive components of herbal medicines.We established roadmaps for oligonucleotide drugs development and optimization of TCM prescriptions.Moreover,the decoctosome,a lipo-nano particle consisting of 0.5%–2.5%of the decoction,demonstrated potent medical effects.We propose a Bencao(herbal)Index,including small-molecule compounds(SM),protein peptides(P),nucleic acid(N),non-nucleic and non-proteinogenic large-molecule compounds(LM)and elements from Mendeleev's periodic table(E),to quantitatively measure the medical effects of botanic medicine.The Bencao s RNA Atlas is a resource for developing gene-targeting oligonucleotide drugs and optimizing botanical medicine,and may provide potential remedies for the theory and practice of one medicine. | Yinghao Cao Yexuan Lin Na Sun Xinyi Du Yixin Dong Song Mei Xingyu Deng Xiaobei Li Shaoting Guo Kegong Tang Jiaqi Liu Xiangyu Qiao Dandan Zhao Yuhao Qin Cong Zhang Tianyi Xin Xiaohu Shi Congzhao Zhou Tao Dong De-an Guo Benedikt MKessler Dong Xu Jingyuan Song Fengming Huang Xiaoyue Wang Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，10： | 2 |
| 13 | Joint 3D Trajectory and Resource Optimization for A UAV Relay-Assisted Cognitive Radio Network显示文摘In this paper,we consider a new spectrum sharing scenario for a cognitive relay network,where a secondary unmanned aerial vehicle(UAV)relay receives information from the ground secondary base station(SBS)and transmits information to the ground secondary user(SU),coexisting with the primary users(PUs)at the same wireless frequency band.We investigate the optimization of the UAV relay’s three-dimensional(3D)trajectory to improve the communication throughput performance of the secondary network subject to the interference constraints of the PUs.The information throughput maximization problem is studied by jointly optimizing the UAV relay’s 3D trajectory and the transmit power of the SBS and the UAV,subject to the constraints on the velocity and elevation of the UAV relay,the maximum and average transmit power,and the information causality,as well as a set of interference temperature(IT)constraints.An efficient algorithm is proposed to solve the admittedly challenging non-convex problem by using the path discretization technique,the successive convex approximation technique and the alternating optimization method.Finally,simulation results are provided to show that our proposed design outperforms other benchmark schemes in terms of the throughput。 | Zhen Wang Fuhui Zhou Yuhao Wang Qihui Wu | 2021 | China Communications2021，18，6： | 2 |
| 14 | DEAP1 encodes a fasciclin-like arabinogalactan protein required for male fertility in rice显示文摘Arabinogalactan proteins(AGPs)are widely distributed in plant cells.Fasciclin-like AGPs(FLAs)belong to a subclass of AGPs that play important roles in plant growth and development.However,little is known about the biological functions of rice FLA.Herein,we report the identification of a male-sterile mutant of DEFECTIVE EXINE AND APERTURE PATTERNING1(DEAP1)in rice.The deap1 mutant anthers produced aberrant pollen grains with defective exine formation and a flattened aperture annulus and exhibited slightly delayed tapetum degradation.DEAP1 encodes a plasma membrane-associated member of groupⅢplant FLAs and is specifically and temporally expressed in reproductive cells and the tapetum layer during male development.Gene expression studies revealed reduced transcript accumulation of genes related to exine formation,aperture patterning,and tapetum development in deap1 mutants.Moreover,DEAP1 may interact with two rice D6 PROTEIN KINASE-LIKE3 s(OsD6PKL3s),homologs of a known Arabidopsis aperture protein,to affect rice pollen aperture development.Our findings suggested that DEAP1 is involved in male reproductive development and may affect exine formation and aperture patterning,thereby providing new insights into the molecular functions of plant FLAs in male fertility. | Dan Zhou Ting Zou Kaixuan Zhang Pingping Xiong Fuxing Zhou Hao Chen Gongwen Li Kaiyou Zheng Yuhao Han Kun Peng Xu Zhang Shangyu Yang Qiming Deng Shiquan Wang Jun Zhu Yueyang Liang Changhui Sun Xiumei Yu Huainian Liu Lingxia Wang Ping Li Shuangcheng Li | 2022 | Journal of Integrative Plant Biology2022，64，7： | 2 |
| 15 | Recent advances in wireless epicortical and intracortical neuronal recording systems显示文摘An implantable brain-computer interface(BCI)has proven to be effective in the field of sensory and motor function restoration and in the treatment of neurological disorders.Using a BCI recording system,we can transform current methods of human interaction with machines and the environment,especially to help those with cognitive and mobility disabilities regain mobility and reintegrate into society.However,most reported work has focused on a simple aspect of the whole system,such as electrodes,circuits,or data transmission,and only a very small percentage of systems are wireless.A miniature,lightweight,wireless,implantable microsystem is key to realizing long-term,real-time,and stable monitoring on freely moving animals or humans in their natural conditions.Here,we summarize typical wireless recording systems,from recording electrodes,processing chips and controllers,wireless data transmission,and power supply to the system-level package for either epicortical electrocorticogram(ECoG)or intracortical local field potentials(LFPs)/spike acquisition,developed in recent years.Finally,we conclude with our vision of challenges in next-generation wireless neuronal recording systems for chronic and safe applications. | Bowen JI Zekai LIANG Xichen YUAN Honglai XU Minghao WANG Erwei YIN Zhejun GUO Longchun WANG Yuhao ZHOU Huicheng FENG Honglong CHANG Jingquan LIU | 2022 | Science China(Information Sciences)2022，65，4： | 2 |
| 16 | Resource Allocation and Trajectories Design for UAV-Assisted Jamming Cognitive UAV Networks显示文摘Unmanned aerial vehicle(UAV)communications are subject to the severe spectrum scarcity problem.Cognitive UAV networks are promising to tackle this issue while the confidential information is susceptible to be eavesdropped.A UAV jamming assisted scheme is proposed.A joint resource allocation and trajectories optimization problem is formulated in a UAV-assisted jamming cognitive UAV network subject to diverse power and trajectory constraints.An alternative optimization algorithm is proposed to solve the challenging non-convex joint optimization problem.Extensive simulation results demonstrate the superiority of our proposed scheme and many meaningful insights are obtained for the practical design of cognitive UAV networks. | Zhenhui Tao Fuhui Zhou Yuhao Wang Xiaodong Liu Qihui Wu | 2022 | China Communications2022，19，5： | 1 |
| 17 | Exploration of B-site alloying in partially reducing Pb toxicity and regulating thermodynamic stability and electronic properties of halide perovskites显示文摘Alloying strategies provide a high degree of freedom for reducing lead toxicity,improving thermodynamic stability, tuning the optoelectronic properties of ABX3 halide perovskites by varying the alloying element species and their contents.Given the key role of B-site cations in contributing band edge states and modulating structure factors in halide perovskites,the partial replacement of Pb2+with different B-site metal ions has been proposed.Although several experimental attempts have been made to date,the effect of B-site alloying on the stability and electronic properties of halide perovskites has not been fully explored.Herein,we take cubic CsPbBr3 perovskite as the prototype material and systematically explore the effects of B-site alloying on Pb-containing perovskites.According to the presence or absence of the corresponding perovskite phase,the ten alloying elements investigated are classified into three types(i.e.,Type Ⅰ:Sn Ge,Ca,Sr;Type Ⅱ:Cd,Mg,Mn;Type Ⅲ:Ba,Zn,Cu).Based on the first-principles calculations,we obtain the following conclusions.First,these B-site alloys will exist as disordered solid solutions rather than ordered structures at room temperature throughout the composition space.Second,the alloying of Sn and Ge enhances the thermodynamic stability of the cubic perovskite host,whereas the alloying of the other elements has no remarkable effect on the thermodynamic stability of the cubic perovskite host.Third,the underlying physical mechanism for bandgap tuning can be attributed to the atomic orbital energy mismatch or quantum confinement effect.Fourth,the alloying of different elements demonstrates the diversity in the regulation of crystal structure and electronic properties,indicating potential applications in photovoltaic s and self-trapped exciton-based light-emitting applications.Our work provides theoretical guidance for using alloying strategies to reduce lead toxicity,enhance stability,and optimize the electronic properties of halide perovskites to meet the needs of optoelectronic applications. | Xinjiang Wang Muhammad Faizan Kun Zhou Hongshuai Zou Qiaoling Xu Yuhao Fu Lijun Zhang | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，3： | 1 |
| 18 | Research on Dynamic and Static Test Methods for Evaluating the Poisson's Ratio of Orien ted Strand Board显示文摘In this article,dynamic method and static method of testing Poisson's ratio of OSB(Oriented Strand Board)were proposed.Through modal and static numerical analyses,the position where the transverse stress is equal to zero was determined.The binary linear regression method was applied to express the gluing position of the strain gauge as a relational express ion that depended on the length-width ratio and width-thickness ratio of the canti-lever plate.Then the longitudinal and transverse Poisson's ratios of OSB were mea sured by the given dynamic and static methods.In addition,the test results of OSB Poisson's ratio were analyzed with the probability distribution of random variables.The results showed that using the proposed dynamic method and static method,the test results for longitudinal and transverse Poisson's ratios of OSB were quite consistent,despite the gluing position of the strain gauges being different.And these OSB Poisson's ratios were accorded with that obtained by the axial tensile method and the four-point bending method.OSB longitudinal and transverse Poisson's ratios followed Weibull distribution. | Yuhao Zhou Yuhang He Zhaoyu Shen Zheng Wang | 2022 | Journal of Renewable Materials2022，10，12： | 1 |
| 19 | Light-Induced Heat Driving Active Ion Transport Based on 2D MXene Nanofluids for Enhancing Osmotic Energy Conversion显示文摘Osmotic energy from the ocean,also called blue energy,serves as a clean,renewable,and vast energy source for the energy demands of the world.Reverse electrodialysis-based blue energy harvesting via ion-selective membranes,by the regulation and manipulation of directional ion transport,has been greatly developed recently.In particular,light has been employed to enhance directional ion transport for energy conversion through an increase in photo-induced surface charge.Here,the authors demonstrate a novel nanofluidic regulation strategy based on the phenomenon of light-induced heat-driven active ion transport through the lamellar MXene membrane.Due to the great light-induced heat effect,a temperature gradient appears as soon as illumination is applied to an off-center position,inducing an actively temperature gradient-driven ionic species transport.By employing this phenomenon,the authors conducted light-induced heat-enhanced osmotic energy conversion and doubled the osmotic energy conversion power density.This study has extended the scope of light-enhanced osmotic energy conversion and could further bring other photothermal materials into this field.Furthermore,the proposed system provides a new avenue of light-controlled ionic transport for ion gathering,desalination,and energy conversion applications. | Pei Liu Teng Zhou Yunfei Teng Lin Fu Yuhao Hu Xiangbin Lin Xiang-Yu Kong Lei Jiang Liping Wen | 2021 | CCS Chemistry2021，3，4： | 1 |
| 20 | Orally administered BZL-s RNA-20 oligonucleotide targeting TLR4 effectively ameliorates acute lung injury in mice显示文摘The global COVID-19 pandemic emerged at the end of December 2019.Acute respiratory distress syndrome(ARDS)and acute lung injury(ALI)are common lethal outcomes of bacterial lipopolysaccharide(LPS),avian influenza virus,and SARS-Co V-2.Toll-like receptor 4(TLR4)is a key target in the pathological pathway of ARDS and ALI.Previous studies have reported that herbal small RNAs(s RNAs)are a functional medical component.BZL-s RNA-20(Accession number:B59471456;Family ID:F2201.Q001979.B11)is a potent inhibitor of Toll-like receptor 4(TLR4)and pro-inflammatory cytokines.Furthermore,BZLs RNA-20 reduces intracellular levels of cytokines induced by lipoteichoic acid(LTA)and polyinosinic-polycytidylic acid(poly(I:C)).We found that BZL-s RNA-20 rescued the viability of cells infected with avian influenza H5N1,SARS-Co V-2,and several of its variants of concern(VOCs).Acute lung injury induced by LPS and SARS-Co V-2 in mice was significantly ameliorated by the oral medical decoctosome mimic(bencaosome;sphinganine(d22:0)+BZL-s RNA-20).Our findings suggest that BZLs RNA-20 could be a pan-anti-ARDS/ALI drug. | Dandan Zhao Yuhao Qin Jiaqi Liu Kegong Tang Shuaiyao Lu Zirui Liu Yexuan Lin Cong Zhang Fengming Huang Jiahui Chang Chang Li Mingyao Tian Yiming Ma Xiaoyun Li Congzhao Zhou Xiao Li Xiaozhong Peng Ningyi Jin Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，7： | 1 |
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