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| 1 | Migration and accumulation of natural gas in Kela-2 gas field显示文摘With the guidance of petroleum system theory,the dynamic filling history of natural gas in the Kela-2 gasfield is analyzed by using a large suite of oil and gas geo-chemistry evidence in combination with the tectonic evolu-tion history and reservoir evolution history. It concludes thatthe Kela-2 gas field was formed by capturing the gas gener-ated during the main gas generation period, while the latekerogen cracking gas contributed a little to the gas field. Itsuggests that the gas generated during the main gas genera-tion accumulated in the early-formed wide-gentle anticline,which is the necessary condition for natural gas to re-migrateand enrich late to form the large-scale gas reservoir. Thenewest research shows that the filling history of gas in theDabei-1, Yinan-2, Tuziluoke and Dina-2 gas fields was re-lated with the natural gas accumulation in the early wide-gentle anticline as well as late re-migration and enrichmentof natural gas. | WANG Zhaoming WANG Tingdong XIAO Zhongyao XU Zhiming LI Mei LIN Feng | 2002 | Chinese Science Bulletin2002，47，S1： | 16 |
| 2 | Identification of the novel recessive gene pi55(t) conferring resistance to Magnaporthe oryzae显示文摘The elite rice cultivar Yuejingsimiao 2 (YJ2) is characterized by a high level of grain quality and yield, and resistance against Magnaporthe oryzae. YJ2 showed 100% resistance to four fungal populations collected from Guangdong, Sichuan, Liaoning, and Heilongjiang Provinces, which is a higher frequency than that shown by the well-known resistance (R) gene donor cultivars such as Sanhuangzhan 2 and 28zhan. Segregation analysis for resistance with F 2 and F 4 populations indicated the resistance of YJ2 was controlled by multiple genes that are dominant or recessive. The putative R genes of YJ2 were roughly tagged by SSR markers, located on chromosomes 2, 6, 8, and 12, in a bulked-segregant analysis using genome-wide selected SSR markers with F 4 lines that segregated into 3 resistant (R):1 susceptible (S) or 1R:3S. The recessive R gene on chromosome 8 was further mapped to an interval 1.9 cM/152 kb in length by linkage analysis with genomic position-ready markers in the mapping population derived from an F 4 line that segregated into 1R:3S. Given that no major R gene was mapped to this interval, the novel R gene was designated as pi55(t). Out of 26 candidate genes predicted in the region based on the reference genomic sequence of the cultivar Nipponbare, two genes that encode a leucine-rich repeat-containing protein and heavy-metalassociated domain-containing protein, respectively, were suggested as the most likely candidates for pi55(t). | HE XiuYing LIU XinQiong WANG Li WANGLing LIN Fei CHENG YongSheng CHEN ZhaoMing LIAO YaoPing PAN QingHua | 2012 | Science China(Life Sciences)2012，55，2： | 15 |
| 3 | Piglets cloned from induced pluripotent stem cells显示文摘 | Nana Fan Jijun Chen Zhouchun Shang Hongwei Dou Guangzhen Ji Qingjian Zou Lu Wu Lixiazi He Fang Wang Kai Liu Na Liu Jianyong Han Qi Zhou Dengke Pan Dongshan Yang Bentian Zhao Zhen Ouyang Zhaoming Liu Yu Zhao Lin Lin Chongming Zhong Quanlei Wang Shouqi Wang Ying Xu Jing Luan Yu Liang Zhenzhen Yang Jing Li Chunxia Lu Gabor Vajta Ziyi Li Hongsheng Ouyang Huayan Wang Yong Wang Yang Yang Zhonghua Liu Hong Wei Zhidong Luan Miguel A Esteban Hongkui Deng Huanming Yang Duanqing Pei Ning Li Gang Pei Lin Liu Yutao Du Lei Xiao Liangxue Lai | 2013 | Cell Research2013，23，1： | 12 |
| 4 | Synthesis,photophysical properties and TD-DFT calculation of four two-photon absorbing triphenylamine derivatives显示文摘In this study,linear absorption,single-photon excited fluorescence,fluorescence quantum yields,fluorescence lifetime and two-photon excited fluorescence of a series of triphenylamine derivatives (L1,L2,L3 and L4) have been measured.L1 and L3 are D--A type dyes,while L2 and L4 are D--D--A type dyes (D=donor,A=acceptor).The investigated compounds consist of triphenylamine-bearing donor-substituted and/or systematically extended-conjugated length,which are designed to gain insight into the effect of the ethoxyl unit and-linkage length on the linear and nonlinear optical properties.The influence of solvent polarity on the photophysical properties was investigated.Employing time-dependent density functional theory (TD-DFT) calculations,the structure-property relationships are discussed. | KONG Lin YANG JiaXiang ZHOU HongPing LI ShengLi HAO FuYing ZHANG Qiong TU YuLong WU JieYing XUE ZhaoMing TIAN YuPeng | 2013 | Science China Chemistry2013，56，1： | 3 |
| 5 | A trilogy antimicrobial strategy for multiple infections of orthopedic implants throughout their life cycle显示文摘Bacteria-associated infection represents one of the major threats for orthopedic implants failure during their life cycles.However,ordinary antimicrobial treatments usually failed to combat multiple waves of infections during arthroplasty and prosthesis revisions etc.As these incidents could easily introduce new microbial pathogens in/onto the implants.Herein,we demonstrate that an antimicrobial trilogy strategy incorporating a sophisticated multilayered coating system leveraging multiple ion exchange mechanisms and fine nanotopography tuning,could effectively eradicate bacterial infection at various stages of implantation.Early stage bacteriostatic effect was realized via nano-topological structure of top mineral coating.Antibacterial effect at intermediate stage was mediated by sustained release of zinc ions from doped CaP coating.Strong antibacterial potency was validated at 4 weeks post implantation via an implanted model in vivo.Finally,the underlying zinc titanate fiber network enabled a long-term contact and release effect of residual zinc,which maintained a strong antibacterial ability against both Staphylococcus aureus and Escherichia coli even after the removal of top layer coating.Moreover,sustained release of Sr2+and Zn2+during CaP coating degradation substantially promoted implant osseointegration even under an infectious environment by showing more peri-implant new bone formation and substantially improved bone-implant bonding strength. | Yikai Wang Wangsiyuan Teng Zengjie Zhang Xingzhi Zhou Yuxiao Ye Peng Lin An Liu Yan Wu Binghao Li Chongda Zhang Xianyan Yang Weixu Li Xiaohua Yu Zhongru Gou Zhaoming Ye | 2021 | Bioactive Materials2021，6，7： | 3 |
| 6 | Performance analysis of LTE-U coexistence network with WiFi using queueing model显示文摘The unforeseen mobile data explosion as well as the scarce of spectrum resource pose a major challenge to the performance of today's cellular networks which are in urgent need of novel solutions to handle such voluminous mobile data. Long term evolution-unlicensed(LTE-U), which extends the LTE standard operating on the unlicensed band, has been proposed to improve system throughput. In LTE-U system, arriving users will contend the unlicensed spectrum resource with wireless fidelity(WiFi) users to transmit data information. Nevertheless, there is no clear consensus as to the benefits of transmission using unlicensed bands for LTE users. To this end, in this paper an analytical model is presented based on a queue system to understand the performance achieved by unlicensed based LTE system taking quality of services(Qo S) and LTE-U users' behaviors into account. To obtain the stead-state solutions of the queue system, a matrix geometric method is used to solve it. Then, the average delay and utilization of unlicensed band for the LTE-U users is derived by using the queuing model. The performance of LTE-U coexistence is evaluated with WiFi using the proposed model and provide some initial insights as to the advantage of LTE-U in practice. | Hu Zhiqun Lu Zhaoming Lin Shangjuan Wen Xiangming Xu Hen | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，5： | 2 |
| 7 | Haplotype-resolved genome of diploid ginger (Zingiber officinale) and its unique gingerol biosynthetic pathway显示文摘Ginger(Zingiber officinale),the type species of Zingiberaceae,is one of the most widespread medicinal plants and spices.Here,we report a high-quality,chromosome-scale reference genome of ginger‘Zhugen’,a traditionally cultivated ginger in Southwest China used as a fresh vegetable,assembled from PacBio long reads,Illumina short reads,and high-throughput chromosome conformation capture(Hi-C)reads.The ginger genome was phased into two haplotypes,haplotype 1(1.53 Gb with a contig N50 of 4.68 M)and haplotype 0(1.51 Gb with a contig N50 of 5.28 M).Homologous ginger chromosomes maintained excellent gene pair collinearity.In 17,226 pairs of allelic genes,11.9%exhibited differential expression between alleles.Based on the results of ginger genome sequencing,transcriptome analysis,and metabolomic analysis,we proposed a backbone biosynthetic pathway of gingerol analogs,which consists of 12 enzymatic gene families,PAL,C4H,4CL,CST,C3’H,C3OMT,CCOMT,CSE,PKS,AOR,DHN,and DHT.These analyses also identified the likely transcription factor networks that regulate the synthesis of gingerol analogs.Overall,this study serves as an excellent resource for further research on ginger biology and breeding,lays a foundation for a better understanding of ginger evolution,and presents an intact biosynthetic pathway for species-specific gingerol biosynthesis. | Hong-Lei Li Lin Wu Zhaoming Dong Yusong Jiang Sanjie Jiang Haitao Xing Qiang Li Guocheng Liu Shuming Tian Zhangyan Wu Bin Wu Zhexin Li Ping Zhao Yan Zhang Jianmin Tang Jiabao Xu Ke Huang Xia Liu Wenlin Zhang Qinhong Liao Yun Ren Xinzheng Huang Qingzhi Li Chengyong Li Yi Wang Baskaran Xavier-Ravi Honghai Li Yang Liu Tao Wan Qinhu Liu Yong Zou Jianbo Jian Qingyou Xia Yiqing Liu | 2021 | Horticulture Research2021，8，1： | 2 |
| 8 | Improving throughput through dynamically tuning contention window size in dense wireless network显示文摘With the boom of wireless devices, the number of wireless users under wireless local area networks(WLANs) has increased dramatically. However, the standard backoff mechanism in IEEE 802.11 adopts fixed initial contention window(CW) size without considering changes of network load, which leads to a high collision probability and low channel utilization in bursty arrivals. In this paper, a novel CW dynamic adjustment scheme is proposed to achieve high throughput performance in dense user environment. In the proposed scheme, the initial CW size is dynamically adjusted to optimum according to the measured packet collision probability. Simulation results show that the proposed scheme can significantly improve the throughput performance. | Lin Shangjuan Wen Xiangming Hu Zhiqun Lu Zhaoming | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，4： | 1 |
| 9 | Activity-trip chaining behavior of urban low-income populations in Nanjing, China: A structural equations analysis显示文摘 | Zhaoming Chu Hui Chen Lin Cheng Xuewu Chen Senlai Zhu | 2014 | Discrete Dynamics in Nature and Society2014，，： | 1 |
| 10 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 11 | Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition显示文摘Sphingosine-1-phosphate(S1P)is an important bioactive lipid molecule in cell membrane metabolism and binds to G proteincoupled S1P receptors(S1PRs)to regulate embryonic development,physiological homeostasis,and pathogenic processes in various organs.S1PRs are lipid-sensing receptors and are therapeutic targets for drug development,including potential treatment of COVID-19.Herein,we present five cryo-electron microscopy structures of S1PRs bound to diverse drug agonists and the heterotrimeric Gi protein.Our structural and functional assays demonstrate the different binding modes of chemically distinct agonists of S1PRs,reveal the mechanical switch that activates these receptors,and provide a framework for understanding ligand selectivity and G protein coupling. | Yuan Yuan Guowen Jia Chao Wu Wei Wang Lin Cheng Qian Li Ziyan Li Kaidong Luo Shengyong Yang Wei Yan Zhaoming Su Zhenhua Shao | 2021 | Cell Research2021，31，12： | 1 |
| 12 | Correction:Haplotype-resolved genome of diploid ginger (Zingiber officinale)and its unique gingerol biosynthetic pathway显示文摘After online publication of the article 1,the authors noticed the affiliation“College of Landscape Architecture and Life Science/Institute of Special Plants,Chongqing University of Arts and Sciences,Yongchuan,Chongqing,China”for author Yiqing Liu was missing. | Hong-Lei Li Lin Wu Zhaoming Dong Yusong Jiang Sanjie Jiang Haitao Xing Qiang Li Guocheng Liu Shuming Tian Zhangyan Wu Bin Wu Zhexin Li Ping Zhao Yan Zhang Jianmin Tang Jiabao Xu Ke Huang Xia Liu Wenlin Zhang Qinhong Liao Yun Ren Xinzheng Huang Qingzhi Li Chengyong Li Yi Wang Baskaran Xavier-Ravi Honghai Li Yang Liu Tao Wan Qinhu Liu Yong Zou Jianbo Jian Qingyou Xia Yiqing Liu | 2021 | Horticulture Research2021，8，1： | 1 |
| 13 | Generation of gene-target dogs using CRISPR/Cas9 system显示文摘Dear Editor,Dogs(Canis familiaris)serve as human companions and are raised to herd livestock,aid hunters,guard homes,perform police and rescue work,and guide the blind.Dogs exhibit close similarities to humans in terms of metabolic,physiological,and anatomical characteristics,and thus are ideal genetic and clinical models to study human diseases(Tsai et al.,2007).Gene target technology is a powerful tool to create new strains of animals with favorable traits.However,thus far,gene-target dogs have not been developed due to their unique species-specific reproductive characteristics,which limits the applications of dogs especially in the field of biomedical research.Recently,clustered regularly interspaced short palindromic repeats(CRISPRs)/CRISPR-associated(Cas)9 system was applied to edit specific genes with a high efficiency(Cong et al.,2013;Mali et al.,2013).Here we attempt to explore the feasibility of producing gene knockout(KO)dogs by using this technology.Beagle dog,the most widely used breed in biomedical research,was used as our animal model.Myostatin(MSTN)was chosen as the first gene of interest. | Qingjian Zou Xiaomin Wang Yunzhong Liu Zhen Ouyang Haibin Long Shu Wei Jige Xin Bentian Zhao Sisi Lai Jun Shen Qingchun Ni Huaqiang Yang Huilin Zhong Li Li Minhua Hu Quanjun Zhang Zhidong Zhou Jiaxin He Quanmei Yan Nana Fan Yu Zhao Zhaoming Liu Lin Guo Jiao Huang Guanguan Zhang Jun Ying Liangxue Lai Xiang Gao | 2015 | Journal of Molecular Cell Biology2015，7，6： | 1 |
| 14 | Genetic variants in fas signaling pathway genes and risk of gastric cancer显示文摘 | Paula L. Hyland Shih‐Wen Lin Nan Hu Han Zhang Lemin Wang Hua Su Chaoyu Wang Ti Ding Ze‐Zhong Tang Jin‐Hu Fan You‐Lin Qiao Xiaoqin Xiong William Wheeler Carol Giffen Kai Yu Jeff Yuenger Laurie Burdett Zhaoming Wang Stephen J. Chanock Margaret A. Tucker San | 2014 | Int J Cancer2014，，4： | 1 |
| 15 | Effects of atresunate on immune function in mice显示文摘 | Lin Peiying Feng Zhaoming Pan Jingqiang | 1995 | Acta Pharmacologica Sinica1995，16，5： | 1 |
| 16 | Estimation of the Postmortem Interval by Measuring Blood Oxidation‑reduction Potential Values显示文摘Accurate estimation of the postmortem interval(PMI)is an important task in forensic practice.In the last half-century,the use of postmortem biochemistry has become an important ancillary method in determining the time of death.The present study was carried out to determine the correlation between blood oxidation-reduction potential(ORP)values and PMIs,and to develop a three-dimensional surface equation to estimate the PMI under various temperature conditions.A total of 48 rabbits were placed into six groups and sacrificed by air embolism.Blood was obtained from the right ventricle of each rabbit,and specimens were stored at 10℃,15℃,20℃,25℃,30℃,and 35℃.At different PMIs(once every 4 h),the blood ORP values were measured using a PB-21 electrochemical analyzer.Statistical analysis and curve fitting of the data yielded cubic polynomial regression equations and a surface equation at different temperatures.Result:The results showed that there was a strong positive correlation between the blood ORP values at different temperatures and the PMI.This study provides another example of using a three-dimensional surface equation as a tool to estimate the PMI at various temperature conditions. | Zhuqing Jiang Meng You Xu Wang Di Lu Haidong Zhang Shengli Di Fengqin Zhang Zhaoming Guo Xiaofei E Lin Chang Jian Xiang Rufeng Bai Tiantong Yang | 2016 | Journal of Forensic Science and Medicine2016，2，1： | 0 |
| 17 | Comparison of methods for identification of cold tolerance of rice显示文摘Under low temperature stress,theplasmamembrane and chloroplast of plant cellsare impaired,resulting in electrolyte leakage and al-teration of chlorophyll fluorescence which can bemeasured with conductometer and fluoremeter.The cold tolerance of excised leaves of several ricevarieties were determined with these two instru-ments at seedling and heading stages to | LIU Yanzhuo CHEN Zhaoming ZHANG Xu LIN Daoxuan KONG Qingui Rice Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510640,China | 1991 | Chinese Rice Research Newsletter1991，，3： | 0 |
| 18 | Analyses of Medical Malpractice in Judicial Appraisal: 505 Cases显示文摘The purpose of this paper is to investigate and analyze the current situation of medical malpractice and make suggestions for preventative measures from a judicial appraisal standpoint.From 2002 to 2011,we conducted and analyzed 505 medicolegal malpractice experiments at the Fada Institute of Forensic Medicine and Science(FIFMS)in Beijing,People’s Republic of China(PRC).We found that the occurrence of medical disputes in surgical and obstetrical/gynecological cases seemed more frequent.The main causes of medical disputes included issues regarding medical ethics,poor quality of the medical staff,equipment malfunctions,and dereliction of duty by the medical personnel.The reasons for dissatisfaction varied among the different levels of medical service.Basic medical services garnered the most complaints.If we can work to improve the moral and professional standards of the medical staff members,intensify their ethics,and foster good relationships between patients and medical professionals,the quality of medical care would improve and the number of disputes regarding medical services would be reduced. | Meng You Xu Wang Di Lu Haidong Zhang Shengli Di Fengqin Zhang Zhaoming Guo Li Yuan Lin Chang Jian Xiang Lili Yu Yingkai Yang Tiantong Yang | 2015 | Journal of Forensic Science and Medicine2015，1，1： | 0 |
| 19 | Abdominal Pain After Cardiac Surgery Caused by Crohn Disease, Intestinal Ischemia, and Colonic Diverticulitis, Respectively: A Report of 3 Cases显示文摘Abdominal complications following cardiac surgery are rare events,but can be fatal if not diagnosed and managed in time.Aggressive treatments offer a better chance for survival in patients with risk factors.This case report describes the clinical presentation and details of 3 recently operated patients who suffered acute abdominal pain after cardiac surgery.The underlying causes were Crohn disease-associated ileal perforation,intestinal necrosis,and diverticulitis-associated colonic perforation.The presentation and management of these severe conditions are discussed. | Huanan Liu Zhaoming Lin Xiaoshen Zhang | 2024 | Cardiology Discovery2024，4，1： | 0 |
| 20 | Ethical Issues Involved in the Rights of Human Clones and Claims to These Rights: A Discussion with Mr. Gan Shaoping显示文摘尽管人们可以通过克隆技术复制出具有大致相同遗传基因的自然生命体,却无法复制出人自身。每一个人都有其独特的人格与尊严。人类关注克隆人权利问题,是在主体及其自由存在的权利、在人类社会对于生命平等关爱及代际正义感表达意义上而言,而不是在克隆人对于自身自然基质、出身及其选择要求的权利意义上而言。人类既无须通过神秘性为自已的尊严辩护,亦无须借助于他物为自己寻求尊严的依据。人的尊严在于平等的自由及其实现。 | Gao Zhaoming Lin Hong | 2005 | Social Sciences in China2005，26，1： | 0 |
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