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| 1 | Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients显示文摘 | Lu Wen Jingyi Li Huahu Guo Xiaomeng Liu Shengmin Zheng Dafang Zhang Weihua Zhu Jianhui Qu Limin Guo Dexiao Du Xiao Jin Yuhao Zhang Yun Gao Jie Shen Hao Ge Fuchou Tang Yanyi Huang Jirun Peng | 2015 | Cell Research2015，25，11： | 19 |
| 2 | Multi-omics analyses of 398 foxtail millet accessions reveal genomic regions associated with domestication,metabolite traits,and antiinflammatory effects显示文摘Foxtail millet(Setaria italica),which was domesticatedfromthewild speciesgreenfoxtail(Setaria viridis),isa richsource of phytonutrientsfor humans.To evaluate how breeding changed themetabolome offoxtail millet grains,we generated and analyzed the datasets encompassing the genomes,transcriptomes,metabolomes,and anti-inflammatory indices from 398 foxtail millet accessions.We identified hundreds of common variants that influence numerous secondary metabolites.We observed tremendous differences in natural variations of the metabolites and their underlying genetic architectures between distinct sub-groups of foxtail millet.Furthermore,we found that the selection of the gene alleles associated with yellow grains led to altered profiles of metabolites such as carotenoids and endogenous phytohormones.Using CRiSPR-mediated genome editing wevalidated the function of PHYTOENE SYNTHASE1(PSY1)gene in affecting milletgrain colorand quality.Interestingly,our in vitro cell inflammation assays showed that 83 metabolites in millet grains have anti-inflammatory effects.Taken together,ourmulti-omics study illustrates how the breeding history of foxtail millet has shaped its metabolite profile.The datasets we generated in this study also provide important resources for further understanding how millet grain quality is affected by different metabolites,laying the foundations for future millet genetic research and metabolome-assisted improvement. | Xukai Li Jianhua Gao Jingyi Song Kai Guo Siyu Hou Xingchun Wang Qiang He Yanyan Zhang Yakun Zhang Yulu Yang Jiaoyan Tang Hailang Wang Staffan Persson Mingquan Huang Lishuai Xu Linlin Zhong Dongqin Li Yongming Liu Hua Wu Xianmin Diao Peng Chen Xiaowen Wang Yuanhuai Han | 2022 | Molecular Plant2022，15，8： | 8 |
| 3 | Characteristics of distribution of Mycobacterium tuberculosis lineages in China显示文摘The genotyping methods of Mycobacterium tuberculosis would dramatically improve our understanding of the molecular epidemiology of tuberculosis. 3,929 isolates, from a National Survey of Drug-Resistant Tuberculosis in 2007 in China, were successfully genotyped by large sequence polymorphisms and 15 loci variable number tandem repeats. We found that 2,905(2,905/3,929, 73.9%) cases belonged to Lineage 2, dominated in the east and central regions, 975 cases(975/3,929, 24.8%) were Lineage 4, highly prevailed in the west regions, and 36 and 13 cases were Lineage 3 and Lineage 1, respectively. We also explored the associations between lineages(Lineage 2 vs. Lineage 4) and clinical characteristics by logistic regression. For Lineage 2, the risk factors were Han-ethnicity population and fever. However, for Lineage 4, they were occupation(farmer), and degree of education(non-literate). Fully understanding of the distribution of Mycobacterium tuberculosis lineage and its risk factors would play a critical role in tuberculosis prevention, control, and treatment. | Haixia Chen Li He Chao Cai Jingyi Liu Junnan Jia Liang Ma Hairong Huang Lixia Wang Xumin Ni Jimin Gao Weimin Li | 2018 | Science China(Life Sciences)2018，61，6： | 7 |
| 4 | Fault Analysis on a New Block Cipher DBlock with at Most Two Fault Injections显示文摘DBlock is a new family of block ciphers proposed by Wu et al. in Science China in 2015, which consists of three variants specified as DBlock-128/192/256.DBlock-n employs a 20-round Feistel-type structure with n-bit block size and n-bit key size. We propose the first fault analysis on DBlock and show that no more than 2 pairs of correct/faulty ciphertexts are needed to retrieve the master key. In the attack, a byte-oriented fault is injected in round 16, and three properties including differential distribution of the Sbox, bijection nature of the linear function and Feistel-type key scheduling are fully utilized to distinguish between the correct and wrong keys. A fault position guessing strategy based on known intermediates is adopted, which efficiently makes the known-fault attack apply to the random fault model. The experimental results show that, with a pair of ciphertexts, 11.820-bit exhaustive search is needed to derive the whole 128-bit key on average. With 2 pairs of ciphertexts, the unique key can be determined within 6.5 minutes. | FENG Jingyi CHEN Hua GAO Si CAO Weiqiong FAN Limin ZHU Shaofeng | 2018 | Chinese Journal of Electronics2018，27，6： | 3 |
| 5 | Accurate annotation of accessible chromatin in mouse and human primordial germ cells显示文摘广泛、精确的染色质改变在初发的细菌房间(PGC ) 期间是必要的为越过代的基因信息的永存的开发。这里,我们报导 DNase 我过分敏感的地点(DHS ) 标记的远侧的 cis 规章的元素(CRE ) 在鼠标和人的 PGC 开发期间显示出时间地限制的活动。把 DHS 地图用作代理,我们精确地在老鼠 PGC 定位 pluripotency 抄写因素的染色体宽的有约束力的地点。出人意料地,我们发现老鼠女性 meiotic 再结合热点能被 DHS 捕获,并且第一次,我们在老鼠女性 PGC 识别了 12,211 个再结合热点。与 meiotic 女性 PGC 的相对照,有丝分裂拘捕的男 PGC 的染色质 ? 通过在远侧的规章的区域的原子抄写因素 Y (NFY ) 绑定是容许的。而且,我们在 PGC CRE 上检验了进化压力,并且比较 genomic 分析表明那只老鼠和人的 PGC CRE evolutionarily 在哺乳动物外面越过脊椎动物树被保存并且出现强壮的保存。因此,我们的结果在鼠标和人的 PGC 开发期间揭示唯一的、时间地可存取的染色质配置。 | Jingyi Li Shijun Shen Jiayu Chen Wenqiang Liu Xiaocui Li Qianshu Zhu Beiying Wang Xiaolong Chen Li Wu Mingzhu Wang Liang Gu Hong Wang Jiqing Yin Cizhong Jiang Shaorong Gao | 2018 | Cell Research2018，28，11： | 2 |
| 6 | Hybrid Channel Access Mechanism Based on Coexistence Scenario of NR-Unlicensed显示文摘With the rapid development of 5G NR(New Radio),the explosive increment of traffic amount is calling the utilization of unlicensed band.3GPP has proposed LAA(Licensed Assisted Access)to use LTE in unlicensed band and pointed out that NR-U(NR-Unlicensed)can reuse most designs of it.However,the existing channel access mechanism of LAA is conservative under the coexistence scenario of NR-U,which leads to the waste of time resource.To address the problem this paper proposes a hybrid channel access mechanism to take advantage of the LBT(Listen-Before-Talk)mechanism of LAA when channel is quite busy and transmit directly with reduced power when it is relatively idle.The channel busy degree is judged by a series of periodically updated adaptive thresholds.System-level simulation verifies that under the coexistence scenario of NR-U the proposed mechanism can achieve higher UPT(User Perceived Throughput)and lower delay than other channel access mechanisms. | Zhening Zhang Jingyi Chen Mingyang Dong Yuehong Gao Jingjing Wang | 2020 | China Communications2020，17，1： | 2 |
| 7 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 8 | Integrated microdevice with a windmill-like hole array for the clog-free,efficient,and self-mixing enrichment of circulating tumor cells显示文摘Circulating tumor cells(CTCs)have tremendous potential to indicate disease progression and monitor therapeutic response using minimally invasive approaches.Considering the limitations of affinity strategies based on their cost,effectiveness,and simplicity,size-based enrichment methods that involve low-cost,label-free,and relatively simple protocols have been further promoted.Nevertheless,the key challenges of these methods are clogging issues and cell aggregation,which reduce the recovery rates and purity.Inspired by the natural phenomenon that the airflow around a windmill is disturbed,in this study,a windmill-like hole array on the SU-8 membrane was designed to perturb the fluid such that cells in a fluid would be able to self-mix and that the pressure acting on cells or the membrane would be dispersed to allow a greater velocity.In addition,based on the advantages of fluid coatings,a lipid coating was used to modify the membrane surface to prevent cell aggregation and clogging of the holes.Under the optimal conditions,recovery rates of 93%and 90%were found for A549 and HeLa cells in a clinical simulation test of our platform with a CTC concentration of 20-100 cells per milliliter of blood.The white blood cell(WBC)depletion rate was 98.7%(n=15),and the CTC detection limit was less than 10 cells per milliliter of blood(n=6).Moreover,compared with conventional membrane filtration,the advantages of the proposed device for the rapid(2 mL/min)and efficient enrichment of CTCs without clogging were shown both experimentally and theoretically.Due to its advantages in the efficient,rapid,uniform,and clog-free enrichment of CTCs,our platform offers great potential for metastatic detection and therapy analyses. | Hao Li Jinze Li Zhiqi Zhang Zhen Guo Changsong Zhang Zixu Wang Qiuquan Guo Chao Li Chuanyu Li Jia Yao Anran Zheng Jingyi Xu Qingxue Gao Wei Zhang Lianqun Zhou | 2022 | Microsystems & Nanoengineering2022，8，1： | 1 |
| 9 | DIW1 encoding a cladeⅠPP2C phosphatase negatively regulates drought tolerance by de-phosphorylating TaSnRK1.1 in wheat显示文摘Drought seriously impacts wheat production(Triticum aestivum L.),while the exploitation and utilization of genes for drought tolerance are insufficient.Leaf wilting is a direct reflection of drought tolerance in plants.Clade A PP2Cs are abscisic acid(ABA)co-receptors playing vital roles in the ABA signaling pathway,regulating drought response.However,the roles of other clade PP2Cs in drought tolerance,especially in wheat,remain largely unknown.Here,we identified a gain-of-function drought-induced wilting 1(DIW1)gene from the wheat Aikang 58 mutant library by map-based cloning,which encodes a cladeⅠprotein phosphatase 2C(TaPP2C158)with enhanced protein phosphatase activity.Phenotypic analysis of overexpression and CRISPR/Cas9 mutant lines demonstrated that DIW1/TaPP2C158 is a negative regulator responsible for drought resistance.We found that TaPP2C158 directly interacts with TaSnRK1.1 and de-phosphorylates it,thus inactivating the TaSnRK1.1–Ta AREB3 pathway.TaPP2C158 protein phosphatase activity is negatively correlated with ABA signaling.Association analysis suggested that C-terminal variation of TaPP2C158 changing protein phosphatase activity is highly correlated with the canopy temperature,and seedling survival rate under drought stress.Our data suggest that the favorable allele with lower phosphatase activity of TaPP2C158 has been positively selected in Chinese breeding history.This work benefits us in understanding the molecular mechanism of wheat drought tolerance,and provides elite genetic resources and molecular markers for improving wheat drought tolerance. | Jingyi Wang Chaonan Li Long Li Lifeng Gao Ge Hu Yanfei Zhang Matthew P.Reynolds Xueyong Zhang Jizeng Jia Xinguo Mao Ruilian Jing | 2023 | Journal of Integrative Plant Biology2023，65，8： | 1 |
| 10 | All-inorganic lead-free NiO_(x)/Cs_(3)Bi_(2)Br_(9) perovskite heterojunction photodetectors for ultraviolet multispectral imaging显示文摘Bismuth-based perovskites are considered to be promising candidates to substitute the toxic lead-based perovskite in optoelectronics due to their excellent optoelectronic properties,high environmental friendliness,and(moisture,light,and heat)stability.However,there are still few reports about high performance bismuth-based perovskite ultraviolet photodetectors,and is more lacking in ultraviolet imaging demonstration.Herein,we reported a self-powered NiO_(x)/Cs_(3)Bi_(2)Br_(9) heterojunction photodetector with excellent photodetection performance by electrochemical depositing NiOx as the hole transport layer.The optimized NiO_(x)/CsaBi_(2)Brg heterojunction photodetector exhibits excellent ultraviolet detection performance with a fast response speed of 3.04/4.65 ms,wide linear dynamic range of 116.6 dB,decent responsivity of 4.33 mA·W^(-1) at 0 V bias,and high detectivity of 1.3×10^(11) jones.The outstanding performance of the optimized NiO_(x)/Cs_(3)Bi_(2)Br_(9) heterojunction photodetector is enough to meet the high-quality ultraviolet imaging.Therefore,we further integrated the optimized NiO_(x)/Cs_(3)Bi_(2)Br_(9) heterojunction photodetector to the transmission mode ultraviolet multispectral imaging system,achieving admirable imaging results at weak light condition.This work will play a positive role in promoting the development of bismuth-based ultraviolet photodetection and ultraviolet multispectral imaging. | Yujin Liu Yuxin Gao Jingyi Zhi Rongqing Huang Wanjun Li Xinyue Huang Genghua Yan Zhong Ji Wenjie Mai | 2022 | Nano Research2022，15，2： | 1 |
| 11 | The Relationship between Chinese Real Estate Market and Stock Market 显示文摘 | Xiaohui Gao Jingyi Li Gu Anthony Yanxiang | 2012 | Journal of International Business Research2012，11，1： | 1 |
| 12 | Finite Element Analysis and Experimental Studies on Hybird Magnetic Bearing 显示文摘 | Liwei Song Jingyi Gao Wei Zhu | 2010 | IEEE Vehicle Power and Propulsion Conference2010，，： | 1 |
| 13 | A dynamic risk-based early warning monitoring system for population-based management of cardiovascular disease显示文摘Risk prediction tools are crucial for population-based management of cardiovascular disease(CVD).However,most prediction models are currently used to assess long-term risk instead of the risk of short-term CVD onset.We developed a Dynamic Risk-based Early wAming Monitoring(DREAM)system using large-scale,real-time electronic health record data from 2010 to 2020 from the CHinese Electronic health Records Research in Yinzhou study.The dynamic risk scores were derived from a 1:5 matched nested case-control set comprising 70,470 individuals(11,745 CVD events)and then validated in a cohort of 81,205 individuals(5950 CVD events).The individuals were Chinese adults aged 40-79 years without a history of CVD at baseline.Eleven predictors related to vital signs,laboratory tests,and health service utilization were selected to establish the dynamic scores.The proposed scores were significantly associated with the subsequent CVD onset(adjusted odds ratio,1.21;95%confidence interval,1.20-1.23).The area under the receiver operating characteristic curves(AUCs)was 0.6010(0.5929-0.6092)and 0.6021(0.5937-0.6105)for the long-term 10-year CVD risk<10%and≥10%groups in the derivation set,respectively.In the long-term 10-year CVD risk>10%group in the validation set,the change in AUC in addition to the long-term risk was 0.0235(0.0155-0.0315).By increasing the risk threshold from 7 to 16 points,the proportion of true subsequent CVD cases among those given alerts increased from 40.61%to 85.31%.In terms of management efficiency,the number needed to manage per CVD case ranged from 2.46 to 1.17 using the risk scores.With the increasing popularity and integration of EHR systems with wearable technology,the DREAM scores can be incorporated into an early-warning system and applied in dynamic,real-time,EHR-based,automated management to support healthcare decision making for individuals,general practitioners,and policymakers. | Xiaofei Liu Qianqian Li Weiye Chen Peng Shen Yexiang Sun Qi Chen Jinguo Wu Jingyi Zhang Ping Lu Hongbo Lin Xun Tang Pei Gao | 2021 | Fundamental Research2021，1，5： | 1 |
| 14 | Papers published from 1995 to 2012 by six Traditional Chinese Medicine universities in China: a bibliometric analysis based on science citation index显示文摘OBJECTIVE: The quality and quantity of published research papers are important in both scientific and technology fields. Although there are several bibliometric studies based on citation analysis, very few have focused on research related to Traditional Chinese Medicine in China. METHODS: The bibliometric method used in this study included the following focuses: publication outputs for each year, paper type, language of publication, distribution of internationally collaborative countries, sources of funding, authorization number, distribution of institutes regarding collaborative publications, research fields, distribution of out-puts in journals, citation data, and h-index. RESULTS: A total of 3809 papers published from 1995 to 2012 were extracted from the science citation index(SCI). The cumulative number of papers from all six universities is constantly increasing. The United States attained the dominant position regarding complementary and alternative medicine research. The Chinese Academy of Sciences was the greatest participator in collaborative efforts. Research field analysis showed that the research mainly focused on pharmacology pharmacy, chemistry, integrative complementary medicine, plant sciences, and biochemistry molecular biology. The Shanghai University of Chinese Medicine had the most citations. CONCLUSION: In recent years, in terms of SCI papers, the six Traditional Chinese Medicine universities studied here have made great advances in scientific research. | Kuo Gao Guihua Tian Qing Ye Xing Zhai Jianxin Chen Tiegang Liu Kaifeng Liu Jingyi Zhao Shengyun Ding | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 1 |
| 15 | Bifunctional Salen-Cu(II) Complex as Efficient Catalyst for N-Arylation of Imidazoles and Suzuki-Miyaura Coupling Reactions显示文摘 | WANG Yi GAO Jingyi ZHAO Mengdan LI Jiamei | 2015 | Chemical Research in Chinese Universities2015，31，4： | 1 |
| 16 | Intrauterine hyperglycemia impairs endometrial receptivity via up-regulating SGK1 in diabetes显示文摘Diabetes is a complex metabolic disorder which can adversely affect reproductive function. SGK1 is found to be up-regulated in multiple tissues of diabetic patients. However, the effects of diabetes on endometrial SGK1 expression and endometrial receptivity remain unknown. In this study, we established a streptozotocin-induced diabetic mouse model and observed reduced implantation sites, retarded development of pinopodes, increased SGK1, and aberrant expression of LIF and MUC1 in the endometrial epithelium. We injected the uterine lumen of normal mice with high-glucose solution and cultured endometrial cells in high-glucose medium to mimic intrauterine hyperglycemia. Both studies provided compelling evidence that hyperglycemia could lead to diminished embryo implantation and dysregulated SGK1, LIF and MUC1. Additionally, through over-expression of SGK1 in vivo and in vitro, we found that enhanced SGK1 also decreased LIF expression, increased MUC1 expression, and attenuated embryo implantation rate. We further identified that hyperglycemia-activated SMAD2/3 might be responsible for the enhancement of SGK1 and verified directly the interaction between SMAD3 and corresponding SMAD binding elements within SGK1 promoter. Taken together, our study confirmed the association between diabetes-related hyperglycemia and endometrial receptivity defects. Hyperglycemia-induced SGK1 has a tremendous role in this pathological process, rendering it as an attractive therapeutic target for diabetes-related reproductive disorders. | Haiyan Xu Jingyi Li Luyang Jin Dan Zhang Bin Chen Xinmei Liu Xianhua Lin Yiting Huang Zhanghong Ke Juan Liu Lin Gao Jianzhong Sheng Hefeng Huang | 2022 | Science China(Life Sciences)2022，65，8： | 1 |
| 17 | Ginsenoside R b3 attenuates oxidative stress and preserves endothelial function in renal arteries from hypertensive rats显示文摘 | Youhua Wang Jinghui Dong Ping Liu Chi Wai Lau Zhen Gao Duan Zhou Jingyi Tang Chi Fai Ng Yu Huang | 2014 | Br J Pharmacol2014，，13： | 1 |
| 18 | Fungal spore record of pastoralism on the NE Qinghai-Tibetan Plateau since the middle Holocene显示文摘Pastoralism is considered a crucial factor in the eventual year-round occupation of high-altitude regions(>3000 m asl)of the Qinghai-Tibetan Plateau,and the northeastern Qinghai-Tibetan Plateau(NE-QTP)was an important corridor for early human occupation.We analyzed fossil fungal spore records for the last 8500 years from a high resolution aeolian section at Langgeri(LGR)on the NE-QTP.Thirty-two fungal spore types were identified in the LGR section,including seven coprophilous types.We combined analysis of coprophilous fungal spores,Cyperaceae,Artemisia,and Hippophae pollen,and the charcoal>50µm fraction to explore the timing and controls of pastoralism on the NE-QTP since the middle Holocene.Pastoralism commenced at LGR shortly before ca.5.5 ka and gradually increased between ca.5.5–3.5 ka,but markedly intensified after ca.2.2 ka,with three periods of growth at ca.2.1–1.9,1.4–1.2,and 0.6–0 ka,and a decline at ca.1.1–0.6 ka.The timing of changes in pastoral activity on the NE-QTP based on the coprophilous fungal spore record is supported by regional archeology and historical documents.Technological and political developments,rather than climate change,played key roles in the long-term fluctuations of regional pastoralism on the NE-QTP in the late Holocene. | Haicheng WEI Chongyi E Ronglei DUAN Jing ZHANG Yongjuan SUN Guangliang HOU Jingyi GAO | 2021 | Science China Earth Sciences2021，64，8： | 1 |
| 19 | Quick photofabrication of functional nanospheres from de novo designed peptides for NIR fluorescence and MR imaging显示文摘Combining the noncovalent and covalent interactions,a series of peptide amphiphiles were designed de novo and synthesized to architect functional assemblies by means of photochemistry.The strand of peptide sequence was structurally capped with photoactive tyrosine-tyrosine(YY)motifs at both termini,and the spacing was filled by alternating of hydrophilic D(L-aspartate)and hydrophobic X(ε-aminocaproic acid)structure.Upon visible-light irradiation,these de novo designed peptides underwent rapid photocrosslinking within merely 10 min.Interestingly,the modulation of alternating D-X pairs in occupying spacer would adjust molecular amphiphilicity,regulate charge distribution,and control particle size and loading capacity of peptide nanospheres(PNS)in aqueous media.With entirely peptide-based matrix,this PNS system could host cationic indicators of fluorescent rhodamine and magnetic GdIII for exemplar near infrared(NIR)fluorescence and magnetic resonance(MR)imaging,which paves a pathway to biomaterial and biomedical applications using de novo designed peptides. | Jingyi Zhao Chen Li Xue-Wang Gao Ke Feng Hao Liu Sijie He Wenhua Zhao Shumin Yang Jianqun Shao Ling Ye Bin Chen Nan Xie Chen-Ho Tung Li-Zhu Wu | 2023 | Nano Research2023，16，3： | 0 |
| 20 | Health status assessment of axial piston pump under variable speed显示文摘The axial piston pump usually works under variable speed conditions.It is important to evaluate the health status of the axial piston pump under the variable speed condition.Aiming at the characteristic signals obtained under different wear levels of the port plate,a feature signal extraction method under variable speed conditions is proposed.Firstly,the combination of complete ensemble empirical mode decomposition with adaptive noise(CEEMDAN)energy spectrum and fast spectral kurtosis principle is used to accurately extract the intrinsic mode function(IMF)component containing the sensitive information of the degraded feature.Then,the aspect ratio analysis method of the angle domain variational mode decomposition(VMD)is used to process the feature index containing the sensitive information of the degraded feature.In order to evaluate the health status of the axial piston pump under variable speed,the vibration reliability analysis method for axial piston pump based on Weibull proportional failure rate model is proposed.The experimental results show that the proposed method can accurately evaluate the health status of the axial piston pump. | 郭锐 Li Hucheng Zhao Zhiqian Zhang Rongbing Zhao Jingyi Gao Dianrong | 2020 | High Technology Letters2020，26，3： | 0 |
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