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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Recent signal and impact of wet-to-dry climatic shift in Xinjiang, China显示文摘The Xinjiang region of China is among the most sensitive regions to global warming.Based on the meteorological and hydrological observation data,the regional wet-to-dry climate regime shifts in Xinjiang were analyzed and the impacts of climatic shift on the eco-hydrological environment of Xinjiang were assessed in this study.The results showed that temperature and precipitation in Xinjiang have increased since the mid-1980 s,showing a warming-wetting trend.However,drought frequency and severity significantly increased after 1997.The climate of Xinjiang experienced an obvious shift from a warm-wet to a warm-dry regime in 1997.Since the beginning of the 21 st century,extreme temperatures and the number of high temperature days have significantly increased,the start date of high temperature has advanced,and the end date of high temperature has delayed in Xinjiang.In addition,the intensity and frequency of extreme precipitation have significantly increased.Consequently,regional ecology and water resources have been impacted by climatic shift and extreme climate in Xinjiang.In response,satellite-based normalized difference vegetation index showed that,since the 1980 s,most regions of Xinjiang experienced a greening trend and vegetation browning after 1997.The soil moisture in Xinjiang has significantly decreased since the late 1990 s,resulting in adverse ecological effects.Moreover,the response of river runoff to climatic shift is complex and controlled by the proportion of snowmelt to the runoff.Runoff originating from the Tianshan Mountains showed a positive response to the regional wet-to-dry shift,whereas that originating from the Kunlun Mountains showed no obvious response.Both climatic shift and increased climate extremes in Xinjiang have led to intensification of drought and aggravation of instability of water circulation systems and ecosystem.This study provides a scientific basis to meet the challenges of water resource utilization and ecological risk management in the Xinjiang region of China. | YAO Junqiang MAO Weiyi CHEN Jing DILINUER Tuoliewubieke | 2021 | Journal of Geographical Sciences2021，31，9： | 4 |
| 3 | Facile fabrication of durable superhydrophobic fabrics by silicon polyurethane membrane for oil/water separation显示文摘Nowadays, oil contamination has become a major reason for water pollution, and presents a global environmental challenge. Although many efforts have been devoted to the fabrication of oil/water separation materials, their practical applications are still hindered by their weak durability, poor chemical tolerance,environmental resistance, and potential negative impact on health and the environment. To overcome these drawbacks, this work offers a facile method to fabricate the eco-friendly and durable oil/water separation membrane fabrics by alkaline hydrolysis and silicon polyurethane coating. The X-ray photoelectron spectroscopy, scanning electron microscopy, and atomic force microscopy results demonstrate that silicon polyurethane membrane could be coated onto the surface of hydrolyzed polyester fabric and form a micro-/nano-scaled hierarchical structure. Based on this, the modified fabric could have a stable superhydrophobic property with a water contact angle higher than 150°, even after repeated washing and mechanical abrasion 800 times, as well as chemical corrosion. Moreover, the modified fabrics show excellent oil/water separation efficiency of up to 99% for various types of oil–water mixture. Therefore, this durable, eco-friendly and cost-efficient superhydrophobic fabric has great potential in large-scale oil/water separation. | Taoyan Mao Runhui Xiao Peng Liu Jiale Chen Junqiang Luo Su Luo Fengwei Xie Cheng Zheng | 2023 | Chinese Journal of Chemical Engineering2023，55，3： | 0 |
| 4 | Templated freezing assembly precisely regulates molecular assembly for free-standing centimeter-scale microtextured nanofilms显示文摘Nature provides diverse models for manufacturing complex and hierarchical materials by controlling molecular assembly at scales ranging from sub-nano to macroscale. However, developing artificial strategies for manufacturing hierarchical materials with comparable machining capabilities to nature is extremely challenging. Here, a templated freezing assembly strategy is reported, enabling simultaneously regulating molecular assembly spatiotemporally to obtain hierarchical materials with structure control from sub-nano to macroscale. In this way, unique centimeter-scale freestanding nanofilms are assembled from diverse molecules, e.g., proteins and conjugated polymers. A generated silk fibroin(SF) nanofilm presents a tunable β-sheet fraction from 5% to 47%, fiber width from 30 to 3,000 nm, and micro-textures with desired shapes. Such a strategy will lay the foundation for customizing hierarchical functional materials from single or multi-component molecules, e.g., desired bioscaffolds with controlled cell adhesion. | Junqiang Mao Huimei Cao Jie Liu Xin Zhou Qingrui Fan Jianjun Wang | 2023 | Science China Chemistry2023，66，3： | 0 |
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