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29篇 您的检索式:作者名="Linhui ZHANG"
    题名 作者 年代 出处 被引量
1RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings显示文摘在有前列腺癌症的不同赛跑的病人之中有显著不同;然而,位于这差别下面的机制仍然保持不清楚。这里,我们在场 transcriptome 的一处全面风景用 RNA-seq,越过关于基因熔化的前列腺癌症 transcriptomes 的揭示巨大的差异,长 noncoding RNA (长 ncRNA ) ,其他的拼接和体的变化从中国人口 14 主要前列腺癌症和他们的配对的正常对应物介绍。14 个肿瘤(21.4%) 中的三个在中国病人怀有 TMPRSS2 尔格熔化,和这熔化的低流行进一步在一个另外的肿瘤集合(10/54=18.5%) 被证实。尤其是,二新奇基因熔化, CTAGE5-KHDRBS3 (20/54=37%) 和 USP9Y-TTTY15 (19/54=35.2%) ,在我们的耐心的队经常发生了。介绍的进一步系统的 transcriptional 识别了是在肿瘤表示的差别的众多的长 ncRNAs。在长 ncRNA 和基因的表示之间的关联的分析建议长 ncRNAs 可以在 transcriptional 规定以外有功能。这研究在中国人口产出新卓见进前列腺癌症的致病。Shancheng Ren Zhiyu Peng Jian-Hua Mao Yongwei Yu Changjun Yin Xin Gao Zilian Cui Jibin Zhang Kang Yi Weidong Xu Chao Chen Fubo Wang Xinwu Guo Ji Lu Jun Yang Min Wei Zhijian Tian Yinghui Guan Liang Tang Chuanliang Xu Linhui Wang Xu Gao Wei Tian Jian Wang Huanming Yang Jun Wang Yinghao Sun 2012Cell Research2012,22,5:66
2Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2.HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou 2019Science China(Physics,Mechanics & Astronomy)2019,62,3:6
3Natural orifice transluminal endoscopic surgery in urology: The Chinese experience显示文摘Objective:To describe the Chinese experience of natural orifice transluminal endoscopic surgery(NOTES)in urology.Methods:From December 2008 to May 2017,35 animal experiments and 305 clinical surgeries of NOTES or natural orifices specimen extractions(NOSE)were performed in China.The animal experiments included five kidney biopsies,24 nephrectomies and six partial nephrectomies.The clinical surgeries included 12 transvaginal NOSE(TV-NOSE),266 hybrid transvaginal NOTES(TV-NOTES)and 27 pure TV-NOTES.The TV-NOSE procedure was performed in five transumbilical laparoendoscopic single-site(U-LESS)nephrectomies,four suprapubic-assisted laparoendoscopic single-site surgery(SA-LESS)nephroureterectomies,and three laparoscopic radical cystectomies.The hybrid TV-NOTES procedure included 210 nephrectomies,31 adrenalectomies,eight nephroureterectomies,13 partial nephrectomies,and four heminephrectomies.The pure TV-NOTES procedure included five renal cyst decortications and 22 nephrectomies.Results:A total of 29 animal experiments were successfully performed.One partial nephrectomy was converted to standard laparoscopic surgery.Two kidney biopsies and two nephrectomies were unsuccessful.A total of 297 clinical surgeries were successfully performed.Six patients who underwent hybrid TV-NOTES were converted to open surgery.Two patients who underwent pure TV-NOTES were converted to SA-LESS.There were 22 major complications,16 occurred intraoperatively and six postoperatively.The mean visual analog score(VAS)of 48 h after the operation was 2.5 points in TV-NOSE,2.3 points in hybrid TV-NOTES and 1.7 points in pure TV-NOTES.The mean follow-up of 50.6(3.0-87.0)months showed that all patients were in good condition.The umbilicus scars were nearly invisible in TV-NOSE and hybrid TV-NOTES.The vaginal incision healed well.Conclusions:TV-NOSE and TV-NOTES are feasible,safe,and effective with little injury,low pain,fast recovery,and good cosmetic outcomes in properly selected patients.They are worth consideration for urological clinical practice.Xiaofeng Zou Guoxi Zhang Tianpeng Xie Yuanhu Yuan Rihai Xiao Gengqing Wu Xiaoning Wang Hui Xu Folin Liu Yuting Wu Yunfeng Liao Quanliang Liu Yinghao Sun Bo Yang Linhui Wang Chuanliang Xu Xiaofeng Gao 2020Asian Journal of Urology2020,7,1:5
4Exploring the Bridge Cases’Role in the Transmission of the SARSCoV-2 Delta Variant—Ruili City,Yunnan Province,China,July–September 2021显示文摘Summary What is already known about this topic?The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Delta variant has proved to have increased transmissibility,and mutations that can cause partial immune escape,which makes its transmission more insidious.What is added by this report?This study showed that probable cases who had negative results in nucleic acid testing but had positive IgM test result and/or IgG test value of over 20 S/CO in antibodies testing.Xiangyu Yan Litao Chang Zekun Wang Linhui Hao Zhongwei Jia Bo Zhang Tiejun Shui 2021China CDC weekly2021,3,50:4
5Design of 60GHz RF Transceiver in CMOS:Challenges and Recent Advances显示文摘With more than 40 years Moore scaling, the speed of CMOS transistors is around 100 GHz. Such fact makes it possible to realize mm-wave circuits in CMOS. However, with the target of achieving broadband and power-efficient operation, 60 GHz CMOS RF transceiver faces severe challenges. After reviewing the technology issues, regarding the 60 GHz applications, this paper discusses design challenges both from the system and the building block levels, and also presents some simulated or measured circuits results.LI Lianming NIU Xiaokang CHEN Linhui CHAI Yuan ZHANG Tao SHI Jun WANG Aili LUO Ying HE Long CHENG Depeng LIU Nan CUI Tiejun YOU Xiaohu 2014China Communications2014,11,6:2
6SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors显示文摘Muta nt isocitrate dehydrog en ase 1(mlDH1)drives tumorigenesis via produci ng on cometabolite R-2-hydroxyglutarate(R-2-HG)across various tumor types.However,mlDHl in hibitors appear only effective in hematological tumors.The therapeutic ben efit in solid tumors remains elusive,likely due to the complex tumor microenvironment.In this study,we discover that R-2-HG produced by IDH1-mutant tumor cells is preferentially imported into vascular endothelial cells and remodels mitochondrial respiration to promote tumor angiogenesis,conferring a therapeutic vulnerability in IDH1-mutant solid tumors.Mechanistically,SLC1 Alz a Na'-depe ndent glutamate tran sporter that is prefere ntially expressed in en dothelial cells,facilitates the in flux of R-2-HG from the tumor microenvironment into the endothelial cells as well as the intracellular trafficking of R-2-HG from cytoplasm to mitochondria.R-2-HG hijacks SLC1A1 to promote mitochondrial Na^(+)/Ca^(2+)exchange,which activates the mitochondrial respiratory chain and fuels vascular en dothelial cell migratio n in tumor an giogenesis.SLC1A1 deficiency in mice abolishes mlDHl-promoted tumor an giogenesis as well as the therapeutic benefit of mlDHl in hibitor in solid tumors.Moreover,we report that HH2301,a newly discovered mlDHl inhibitor,shows promising efficacy in treating IDH1-mutant cholangiocarcinoma in preclinical models.Together,we identify a new role of SLC1A1 as a gatekeeper of R-2-HG-mediated crosstalk between IDH1-mutant tumor cells and vascular en dothelial cells,and dem on strate the therapeutic potential of mlDHl in hibitors in treating IDH1-muta nt solid tumors via disrupting R-2-HG-promoted tumor angiogenesis.Xiaomin Wang Ziqi Chen Jun Xu Shuai Tang Nan An Lei Jiang Yixiang Zhang Shaoying Zhang Qingli Zhang Yanyan Shen Shijie Chen Xiaojing Lan Ting Wang Linhui Zhai Siyuwei Cao Siqi Guo Yingluo Liu Aiwei Bi Yuehong Chen Xiameng Gai Yichen Duan Ying Zheng Yixian Fu Yize Li Liang Yuan Linjiang Tong Kun Mo Mingcheng Wang Shu-Hai Lin Minjia Tan Cheng Luo Yi Chen Jia Liu Qiansen Zhang Leping Li Min Huang 2022Cell Research2022,32,7:2
7Maternal genetic history of ancient Tibetans over the past 4000 years显示文摘The settlement of the Tibetan Plateau epitomizes human adaptation to a high-altitude environment that poses great challenges to human activity.Here,we reconstruct a 4000-year maternal genetic history of Tibetans using 128 ancient mitochondrial genome data from 37 sites in Tibet.The phylogeny of haplotypes M9a1a,M9a1b,D4g2,G2a’c,and D4i show that ancient Tibetans share the most recent common ancestor with ancient Middle and Upper Yellow River populations around the Early and Middle Holocene.In addition,the connections between Tibetans and Northeastern Asians vary over the past 4000 years,with a stronger matrilineal connection between the two during 4000 BPe3000 BP,and a weakened connection after 3000 BP,that are coincident with climate change,followed by a reinforced connection after the Tubo period(1400 BPe1100 BP).Besides,an over 4000-year matrilineal continuity is observed in some of the maternal lineages.We also find the maternal genetic structure of ancient Tibetans is correlated to the geography and interactions between ancient Tibetans and ancient Nepal and Pakistan populations.Overall,the maternal genetic history of Tibetans can be characterized as a long-term matrilineal continuity with frequent internal and external population interactions that are dynamically shaped by geography,climate changes,as well as historical events.Ganyu Zhang Can Cui Shargan Wangdue Hongliang Lu Honghai Chen Lin Xi Wei He Haibing Yuan Tinley Tsring Zujun Chen Feng Yang Tashi Tsering Shuai Li Norbu Tashi Tsho Yang Yan Tong Xiaohong Wu Linhui Li Yuanhong He Peng Cao Qingyan Dai Feng Liu Xiaotian Feng Tianyi Wang Ruowei Yang Wanjing Ping Ming Zhang Xing Gao Yichen Liu Wenjun Wang Qiaomei Fu 2023Journal of Genetics and Genomics2023,50,10:1
8Quantitative analysis of work hardening and dynamic softening behaviors of Cu-6 wt pct Ag binary alloy based on true stress vs strain curves显示文摘The work hardening and dynamic softening behaviors of Cu-6 wt pct Ag binary alloy were studied by hot compression tests under temperature range of 700-850℃ at strain rates of 0.01-10s-1.The critical conditions for the onset of dynamic recrystallization (DRX) were determined based on the conventional strain hardening rate curves (dσ/dε versus σ).The progress of DRX was analyzed by constructing a model of volume fraction of DRX based on flow curves.The strain rate sensitivity (SRS) and activation volume V were calculated.The results show that the DRX almost can happen under all deformation conditions even at high Z deformations where dynamic recovery (DRV) is the main softening mechanism.The DRX fraction curves can well predict the DRX behavior.The strain has significant effects on SRS at the strain rates of 0.01s-1 and 10s-1 which are mainly due to off-equilibrium saturation of dislocation storage and annihilation while the effects of the temperature on the SRS are based on the uniformity of microstructure distribution.The formation of 'forest' of dislocation is contributed to the low activation volume V*(about 168b3) which is independent of Z values at the initial deformation.The cross-slip due to dislocation piled up beyond the grain boundaries or obstacles is related to the low activation volume under the high Z deformation conditions at high strain (ε=0.6) while the fine DRX grains coarsed is the main reason for the high activation volume at low Z under the same strain conditions.Menghan WANG Wenhao WANG Jingjing DONG Linhui ZHANG Yunping LI Akihiko CHIBA 2012Acta Metallurgica Sinica(English Letters)2012,25,6:1
9Comparative proteomics analysis of Pichia pastoris cultivating in glucose and methanol显示文摘The methylotrophic yeast Pichia pastoris(syn.Komagataella phaffii)has been extensively engineered for protein production,and is attracting attention as a chassis cell for methanol biotransformation toward production of small molecules.However,the relatively unclear methanol metabolism hampers the metabolic rewiring to improve the biosynthetic efficiency.We here performed a label-free quantitative proteomic analysis of Pichia pastoris when cultivated in minimal media containing methanol and glucose,respectively.There were 243,158 up-regulated proteins and 244,304 down-regulated proteins in log and stationary phase,respectively,when cultivated in methanol medium compared with that of glucose medium.Peroxisome enrichment further improved the characterization of more differentially expressed proteins(481 proteins in log phase and 524 proteins in stationary phase).We demonstrated the transaldolase isoenzyme(Tal2,Protein ID:C4R244)was highly up-regulated in methanol medium cultivation,which plays an important role in methanol utilization.Our work provides important information for understanding methanol metabolism in methyltrophic yeast and will help to engineer methanol biotransformation in P.pastoris.Rui Hou Linhui Gao Jianhui Liu Zhen Liang Yongjin J.Zhou Lihua Zhang Yukui Zhang 2022Synthetic and Systems Biotechnology2022,7,3:1
10Engineering of Reversible Luminescent Probes for Real-Time Intravital Imaging of Liver Injury and Repair显示文摘As the major organ for drug metabolism and detoxification,the liver is prone to damage and severely impaired functionality.The treatment of liver diseases is based on a clear understanding of the process underlying liver injury and repair.However,intravital real-time imaging of liver injury and repair is still limited due to the lack of in vivo reversible visualization methods.To this end,we proposed a rational design strategy for the development of a reversible upconversion luminescence nanoprobe that allows real-time and in vivo imaging of liver injury and repair processes.As a proof of concept,we first developed a small molecule probe NB3 which can reversibly respond to related analytes of early liver injury[peroxynitrite(ONOO−)]and liver repair[glutathione(GSH)].The small molecule probe was then integrated with a core–shell upconversion nanoparticle to form a sophisticated nanoprobe.Compared with traditional small molecule probes,this nanoprobe exhibited a higher selectivity to ONOO−,longer retention time in liver,and wider dynamic response range to GSH after oxidation by ONOO−.The novel nanoprobe facilitated the successful monitoring and discrimination among the different degrees of liver injury and repair in a mouse model.Xiao Liu Linhui He Xiangyang Gong Yue Yang Dan Cheng Juanjuan Peng Lu Wang Xiao-Bing Zhang Lin Yuan 2022CCS Chemistry2022,4,1:1
11The path to 5G:mmWave aspects显示文摘The wide spectrum and propagation characteristics over the air give mmWave communication unique advantages as well as design challenges for 5G applications.To increase the system speed,capacity,and coverage,there is a need for innovation in the RF system architecture,circuit,antenna,and package in terms of implementation opportunities and constraints.The discuss mmWave spectrum characteristics,circuits,RF system architecture,and their implementation issues are discussed.Moreover,the transmitter key components,i.e.,the receiver,antenna,and packaging are reviewed.LI Lianming NIU Xiaokang CHAI Yuan CHEN Linhui ZHANG Tao CHENG Depeng XIA Haiyang WANG Jiangzhou CUI Tiejun YOU Xiaohu 2016Journal of Communications and Information Networks2016,1,2:1
12Polysaccharide hemostatic system for hemostasis management in colorectal endoscopic mucosal resection显示文摘Rui Huang Yanglin Pan Na Hui Xuegang Guo Linhui Zhang Xiangping Wang Rongchun Zhang Hui Luo Xiong Zhou Qin Tao Zhiguo Liu Kaichun Wu 2014Digestive Endoscopy2014,,1:1
13CENP-A的Ser68位动态磷酸化调控它在着丝粒区域的细胞周期依赖性装配显示文摘细胞出版社《发育细胞》创刊于2001年,本刊致力于搭建细胞生物学与发育生物学两大学科之间的桥梁。受过专业博士训l练的科学编辑与作者、审稿人、编委会成员共同合作,及时发布横跨两个领域令人振奋的研究成果,强调两个领域之间共同面临的问题以及相互之间的关系。该杂志2015年公布的影响因子为9.708。Zhouliang Yu Xiang Zhou Wenjing Wang Wenqiang Deng Junnan Fang Hao Hu Zichen Wang Shangze Li Lei Cui Jing Shen Linhui Zhai Shengyi Peng Jiemin Wong Shuo Dong Zengqiang Yuan Guangshuo Ou Xiaodong Zhang Ping Xu Jizhong Lou Na Yang Ping Chen Rui-Ming Xu 李国红 2016科学新闻2016,0,1:1
14KLF4 facilitates chromatin accessibility remodeling in porcine early embryos显示文摘Chromatin accessibility remodeling driven by pioneer factors is critical for the development of early embryos.Current studies have illustrated several pioneer factors as being important for agricultural animals,but what are the pioneer factors and how the pioneer factors remodel the chromatin accessibility in porcine early embryos is not clear.By employing low-input DNase-seq(liDNase-seq),we profiled the landscapes of chromatin accessibility in porcine early embryos and uncovered a unique chromatin accessibility reprogramming pattern during porcine preimplantation development.Our data revealed that KLF4 played critical roles in remodeling chromatin accessibility in porcine early embryos.Knocking down of KLF4 led to the reduction of chromatin accessibility in early embryos,whereas KLF4 overexpression promoted the chromatin openness in porcine blastocysts.Furthermore,KLF4 deficiency resulted in mitochondrial dysfunction and developmental failure of porcine embryos.In addition,we found that overexpression of KLF4 in blastocysts promoted lipid droplet accumulation,whereas knockdown of KLF4 disrupted this process.Taken together,our study revealed the chromatin accessibility dynamics and identified KLF4 as a key regulator in chromatin accessibility and cellular metabolism during porcine preimplantation embryo development.Wei Zhu Guowei Bu Ruifeng Hu Jixiang Zhang Lianyong Qiao Kai Zhou Tingting Wang Qiao Li Jingjing Zhang Linhui Wu Yali Xie Taotao Hu Shichun Yang Jiaqi Guan Xiaoyu Chu Juanjuan Shi Xia Zhang Falong Lu Xin Liu Yi-Liang Miao 2024Science China(Life Sciences)2024,67,1:0
15Effects of Si Content on Microstructure and Mechanical Properties of 8079 Aluminum Alloy显示文摘Because of high strength and low breaking rate,8079 aluminum alloy has become the main material of double zero aluminum foil.However,there are still many problems in the manufacturing process,such as broken belt,pinhole and so on.As the main influencing element,Si has a great influence on the alloy.In this work,the influences of Si with various contents on microstructural evolution and mechanical properties of 8079 aluminum alloy were analyzed by energy dispersive spectrometer(EDS),optical microscope(OM),X-Ray diffraction analyzer(XRD),universal testing machine and Vickers hardness tester.The results showed that the primary Si phase was tiny and dispersed in the alloy when the content of Si is less than 1.3%.As the second phases dispersion strengthening,the Si phase can improve the strength of the alloy.However,when the Si content was too high,the Si phase increased and coarsened.Meanwhile,Fe-rich phase which increased by Si decreased the fine grain strengthening and the second phases strengthening mechanism.The coarse Si phase and the Fe-rich phase are brittle phase,which are easy to become the crack source in the process of material deformation and reduce the strength and toughness of the alloy.The mechanical property test shows that the performance of 8079 aluminum alloy is the best when the Si content is 1.3%.Linhui ZHANG Xiaoshu KANG Binnian ZHONG 2020Research and Application of Materials Science2020,2,1:0
16Initial experience of laparoendoscopic single-site radical prostatectomy with a novel purpose-built robotic system显示文摘Objective This prospective single-arm clinical trial aimed to evaluated the feasibility and safety of the application of the SHURUI system(Beijing Surgerii Technology Co.,Ltd.,Beijing,China),a novel purpose-built robotic system,in single-port robotic radical prostatectomy.Methods Sixteen patients diagnosed with prostate cancer were prospectively enrolled in and underwent robotic radical prostatectomy from October 2021 to August 2022 by the SHURUI single-port robotic surgical system.The demographic and baseline data,surgical,oncological,and functional outcomes as well as follow-up data were recorded.Results The mean operative time was 226.3(standard deviation[SD]52.0)min,and the mean console time was 183.4(SD 48.3)min,with the mean estimated blood loss of 116.3(SD 90.0)mL.The mean length of postoperative hospital stay was 4.50(SD 0.97)days.Two patients had postoperative complications(Clavien-Dindo Grade II),and both patients improved after conservative treatment.All patients’postoperative prostate-specific antigen levels decreased to below 0.2 ng/mL 1 month after discharge.The mean prostate-specific antigen level further decreased to a mean of 0.0219(SD 0.0641)ng/mL 6 months after surgery.Thirty days postoperatively,12 out of 16 patients reported using no more than one urinary pad per day,and all patients reported satisfactory urinary control without the need for pads 6 months after surgery.Conclusion The SHURUI system is safe and feasible in performing radical prostatectomy via both transperitoneal and extraperitoneal approaches.Tumor control and urinary continence were satisfying for patients enrolled in.The next phase involves conducting a large-scale,multicenter randomized controlled trial to thoroughly assess the effectiveness and safety of the new technology in a broader population.Zheng Wang Chao Zhang Chengwu Xiao Yang Wang Yu Fang Baohua Zhu Shouyan Tang Xiaofeng Wu Hong Xu Yi Zhou Lingfen Wu Zhenjie Wu Bo Yang Yi He Yi Liu Linhui Wang 2023Asian Journal of Urology2023,10,4:0
17An improved evaluation of the neutron background in the PandaX-Ⅱ experiment显示文摘In dark matter direct detection experiments,neutron is a serious source of background,which can mimic the dark matter-nucleus scattering signals.In this paper,we present an improved evaluation of the neutron background in the PandaX-II dark matter experiment by a novel approach.Instead of fully relying on the Monte Carlo simulation,the overall neutron background is determined from the neutron-induced high energy signals in the data.In addition,the probability of producing a dark-matter-like background per neutron is evaluated with a complete Monte Carlo generator,where the correlated emission of neutron(s)andγ(s)in the(α,n)reactions and spontaneous fissions is taken into consideration.With this method,the neutron backgrounds in the Run 9(26-ton-day)and Run 10(28-ton-day)data sets of PandaX-II are estimated to be(0.66±0.24)and(0.47±0.25)events,respectively.QiuHong Wang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui YingJie Fan DeQing Fang ChangBo Fu LiSheng Geng Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo Ke Han ChangDa He Di Huang Yan Huang YanLin Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju YiHui Lai Kun Liang HuaXuan Liu JiangLai Liu WenBo Ma YuGang Ma YaJun Mao Yue Meng Parinya Namwongsa KaiXiang Ni JinHua Ning XuYang Ning XiangXiang Ren ChangSong Shang Lin Si AnDi Tan AnQing Wang HongWei Wang Meng Wang SiGuang Wang XiuLi Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu Jumin Yuan Dan Zhang HongGuang Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou 2020Science China(Physics,Mechanics & Astronomy)2020,63,3:0
18Constraining self-interacting dark matter with the full dataset of PandaX-II显示文摘Self-interacting dark matter(SIDM)is a leading candidate proposed to solve discrepancies between predictions of the prevailing cold dark matter theory and observations of galaxies.Many SIDM models predict the existence of a light force carrier that mediates strong dark matter self-interactions.If the mediator couples to the standard model particles,it could produce characteristic signals in dark matter direct detection experiments.We report searches for signals of SIDM models with a light mediator using the full dataset of the PandaX-II experiment,basing on a total exposure of 132 tonne-days.No significant excess over background is found,and our likelihood analysis leads to a strong upper limit on the dark matter-nucleon coupling strength.We further combine the PandaX-II constraints and those from observations of the light element abundances in the early universe,and show that direct detection and cosmological probes can provide complementary constraints on dark matter models with a light mediator.Jijun Yang Abdusalam Abdukerim Wei Chen Xun Chen Yunhua Chen Chen Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Shengming He Di Huang Yan Huang Ran Huo Yanlin Huang Zhou Huang Xiangdong Ji Yonglin Ju Shuaijie Li Qing Lin Huaxuan Liu Jianglai Liu Xiaoying Lu Wenbo Ma Yugang Ma Yajun Mao Yue Meng Nasir Shaheed Kaixiang Ni Jinhua Ning Xuyang Ning Xiangxiang Ren Changsong Shang Guofang Shen Lin Si Andi Tan Anqing Wang Hongwei Wang Meng Wang QiuHong Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Mengmeng Wu Shiyong Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Yong Yang Chunxu Yu Hai-Bo Yu Jumin Yuan Ying Yuan Xinning Zeng Dan Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou 2021Science China(Physics,Mechanics & Astronomy)2021,64,11:0
19Huge pyogenic liver abscess(PLA)in an elderly patient with dia-betes following the pancreaticoduodenectomy显示文摘We described an elderly female with type 2 diabetes referred to our hospital with fever, nausea and upper abdominal pain. The patient had got duodenal tumor and received the pancreaticoduodenectomy(PD)12 years ago. The laboratory examinations revealed white blood cells(WBC)increasing and severe hypocalcemia. Abdominal computed tomography(CT)revealed a huge gas-forming pyogenic liver abscess(PLA)in left lobe of the liver. The patient got cured after correction of calcium metabolism disorders, treatment with antibiotic and receiving percutaneous tube drainage. We concluded that we should remain on high alert of those patients with DM and the history of cancer, when he or she gets fever of unknown origin and abdominal tenderness. PLA should be considered.Liu Yunfeng Li Linhui Zhang Yi Xu Linxin Yin Jianhong Sun Li Yang Jing 2019中华内分泌外科杂志2019,13,3:0
20Determination of Double Beta Decay Half-Life of 136Xe with the PandaX-4T Natural Xenon Detector显示文摘Precise measurement of two-neutrino double beta decay(DBD)half-life is an important step for the searches of Majorana neutrinos with neutrinoless double beta decay.We report the measurement of DBD half-life of 136xe using the Pandax-4T dual-phase Time Projection Chamber(TPC)with 3.7-tonne natural xenon and the first 94.9-day physics data release.Lin Si Zhaokan Cheng Abdusalam Abdukerim Zihao Bo Wei Chen Xun Chen Yunhua Chen Chen Cheng Yunshan Cheng Xiangyi Cui Yingjie Fan Deqing Fang Changbo Fu Mengting Fu Lisheng Geng Karl Giboni Linhui Gu Xuyuan Guo Ke Han Changda He Jinrong He Di Huang Yanlin Huang Zhou Huang Ruquan Hou Xiangdong Ji Yonglin Ju Chenxiang Li Jiafu Li Mingchuan Li Shu Li Shuaijie Li Qing Lin Jianglai Liu Xiaoying Lu Lingyin Luo Yunyang Luo Wenbo Ma Yugang Ma Yujun Mao Yue Meng Nasir Shaheed Xiaofeng Shang Xuyang Ning Ningchun Qi Zhicheng Qian Xiangxiang Ren Changsong Shang Guofang Shen Wenliang Sun Andi Tan Yi Tao Anqing Wang Meng Wang Qiuhong Wang Shaobo Wang Siguang Wang Wei Wang Xiuli Wang Zhou Wang Yuehuan Wei Mengmeng Wu Weihao Wu Jingkai Xia Mengjiao Xiao Xiang Xiao Pengwei Xie Binbin Yan Xiyu Yan Yong Yang Chunxu Yu Jumin Yuan Ying Yuan Zhe Yuan Dan Zhang Minzhen Zhang Peng Zhang Shibo Zhang Shu Zhang Tao Zhang Li Zhao Qibin Zheng Jifang Zhou Ning Zhou Xiaopeng Zhou Yong Zhou 2023Research2023,,2:0
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