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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Climate and environment reconstruction during the Medieval Warm Period in Lop Nur of Xinjiang, China显示文摘We made multi-proxy analysis of 14C, grain size, microfossils, plant seeds, and geochemical elements on samples from a profile in the central West Lake of Lop Nur. The grain size suggests relatively stable sedimentary environment around the Medieval Warm Period (MWP) with weak storm effect, which is followed by frequent strong storm events. Abundant microfossils and plant seeds in this stage indicate a warm and humid fresh to brackish lake environment. C, N, and stable elements are high in content in the sediments while Rb/Sr, Ba/Sr, and Ti/Sr are in a steady low level. In addition, plenty of red willows lived here prior to about 700 a B.P., indicating a favorable environmental condition. The results indicate that the environment in Lop Nur and its west bank turned to be favorable at about 2200 a B.P., where the Loulan Culture began to thrive. Then the climate and environment came to be in the good condition in the Tang and Song Dynasties, when the storm effect became weaker, rainfall increased and the salty lake water turned to be brackish to fresh lake water. Hence, limnic biomass increased with higher species diversity. | MA ChunMei WANG FuBao CAO QiongYing XIA XunCheng LI ShengFeng Li XuSheng | 2008 | Chinese Science Bulletin2008，53，19： | 13 |
| 3 | Approach to increasing the quality of pressure-relieved gas drained from protected coal seam using surface borehole and its industrial application显示文摘 | Yingke Liu Fubao Zhou Jianlong Wang Jun Liu | 2015 | International Journal of Coal Science & Technology2015，2，1： | 13 |
| 4 | A preliminary study of chronology for a newly-discovered ancient city and five archaeological sites in Lop Nor, China显示文摘In the past century, it has long been debated in the archeological, historical, geographical, and many other related communities where the capital of the Luolan and Shanshan states was in the Lop Nor region. This paper presents three AMS radiocarbon ages from a newly-discovered ancient city at about 6.3 km to the northwest of the Xiaohe Graveyard, and fifteen new radiocarbon ages from the Loulan (LA), LE, Qieerqiduke, Milan, and Tuyin sites in Lop Nor. The new investigation shows that the age of newly-discovered ancient city is at ca. 440–500 AD, belonging to the Northern Wei Dynasty (386–534 AD). This is about 100–300 years younger than Loulan (ca. 100–230 AD), LE (ca. 230–300 AD), Qieerqiduke (ca. 200 AD), and Tuyin (ca. 100 AD). A wooden beam from Milan fortress is dated to ca. 370 AD, while the age on north wall at west gate of the fortress is younger, around 770 AD, suggesting that its construction time might be at the Tang Dynasty. According to 14C ages, cultural relic style, and the geographical location, the newly-discovered ancient city is probably attributed to 'Zhubin City', as documented in the historical literature. Temporally, we name the city 'ancient Zhubin River City'. However, the characteristics and functions of this ancient city are largely unknown and need more detailed archaeological excavation and investigation in the future. Given its location near the ancient postal relay of Alagan on the crossroad, there is no doubt that the newly-discovered city was at an important geographical position on the Silk Road, no matter whether it was called 'Zhubin City', or 'Lielo City', or the capital of Loulan state–'Yuni City'. Our findings provide new evidence for the temporal and spatial distribution of ancient relic sites and the development of civilization in western China, thus contributing to our understanding of the relationship between human activities and environmental change in the Lop Nor region. | LU HouYuan XIA XunCheng LIU JiaQi QIN XiaoGuang WANG FuBao YIDILISI Abuduresule ZHOU Li Ping MU GuiJin JIAO YingXin LI JingZhi | 2010 | Chinese Science Bulletin2010，55，1： | 8 |
| 5 | Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes显示文摘Objective: There are no comprehensive studies on survival outcomes and optimal treatment protocols for cervical esophageal cancer(CEC), due to its rare clinical prevalence. Our objective was to determine the relationship between pathological characteristics, treatment protocols, and survival outcomes in Chinese CEC patients.Methods: A total of 500 Chinese CEC patients were selected from our 500,000 esophageal and gastric cardia carcinoma database(1973–2018). There were two main groups: patients treated with surgery, and patients receiving non-surgical treatments(radiotherapy, radiochemotherapy, and chemotherapy). The Chi-square test and Kaplan–Meier method were used to compare the continuous variables and survival.Results: Among the 500 CEC patients, 278(55.6%) were male, and the median age was 60.9 ± 9.4 years. A total of 496 patients(99.2%) were diagnosed with squamous cell carcinoma. In 171(34.2%) patients who received surgery, 22(12.9%) had undergone laryngectomy. In 322(64.4%) patients who received non-surgical treatments, 245(76.1%) received radiotherapy. Stratified survival analysis showed that only T stage was related with survival outcomes for CEC patients in the surgical group, and the outcomes between laryngectomy and non-laryngectomy patients were similar. It was noteworthy that the 5-year survival rate was similar in CEC patients among the different groups treated with surgery, radiotherapy, chemotherapy, or radiochemotherapy(P = 0.244). Conclusions: The CEC patients had similar survival outcomes after curative esophagectomy and radiotherapy, including those with or without total laryngectomy. These findings suggest that radiotherapy could be the initial choice for treatment of Chinese CEC patients. | Peinan Chen Xueke Zhao Fuyou Zhou Xin Song Shoujia Hu Yan Jin Xianzeng Wang Xuena Han ZongminFan Ran Wang Bei Li Wenli Han Panpan Wang Jilin Li Lixin Wan Liguo Zhang Qide Bao Fubao Chang Yanru Qin Zhiwei Chang Jianwei Ku Haijun Yang Ling Yuan Jingli Ren Xuemin Li Lidong Wang | 2020 | Cancer Biology & Medicine2020，17，1： | 6 |
| 6 | Environmental significance exploration to Tamarix ConeAge Layer in Lop Nur Lake region显示文摘 | XlA Xuncheng ZHAO Yuanjie WANG Fubao CAO Qiongying | 2005 | Chinese Science Bulletin2005，50，20： | 6 |
| 7 | Chinese expert consensus on conversion therapy for hepatocellular carcinoma(2021 edition)显示文摘Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma(HCC)have resulted in improved response rates.This has provided an opportunity for selected patients with initially unresectable HCC to achieve adequate tumor downstaging to undergo surgical resection,a‘conversion therapy’strategy.However,conversion therapy is a new approach to the treatment of HCC and its practice and treatment protocols are still being developed.Review the evidence for conversion therapy in HCC and develop consensus statements to guide clinical practice.Evidence review:Many research centers in China have accumulated significant experience implementing HCC conversion therapy.Preliminary findings and data have shown that conversion therapy represents an important strategy to maximize the survival of selected patients with intermediate stage to advanced HCC;however,there are still many urgent clinical and scientific challenges for this therapeutic strategy and its related fields.In order to summarize and learn from past experience and review current challenges,the Chinese Expert Consensus on Conversion Therapy for Hepatocellular Carcinoma(2021 Edition)was developed based on a review of preliminary experience and clinical data from Chinese and non-Chinese studies in this field and combined with recommendations for clinical practice.Sixteen consensus statements on the implementation of conversion therapy for HCC were developed.The statements generated in this review are based on a review of clinical evidence and real clinical experience and will help guide future progress in conversion therapy for patients with HCC. | Hui-Chuan Sun Jian Zhou Zheng Wang Xiufeng Liu Qing Xie Weidong Jia Ming Zhao Xinyu Bi Gong Li Xueli Bai Yuan Ji Li Xu Xiao-Dong Zhu Dousheng Bai Yajin Chen Yongjun Chen Chaoliu Dai Rongping Guo Wenzhi Guo Chunyi Hao Tao Huang Zhiyong Huang Deyu Li Gang Li Tao Li Xiangcheng Li Guangming Li Xiao Liang Jingfeng Liu Fubao Liu Shichun Lu Zheng Lu Weifu Lv Yilei Mao Guoliang Shao Yinghong Shi Tianqiang Song Guang Tan Yunqiang Tang Kaishan Tao Chidan Wan Guangyi Wang Lu Wang Shunxiang Wang Tianfu Wen Baocai Xing Bangde Xiang Sheng Yan Dinghua Yang Guowen Yin Tao Yin Zhenyu Yin Zhengping Yu Bixiang Zhang Jialin Zhang Shuijun Zhang Ti Zhang Yamin Zhang Yubao Zhang Aibin Zhang Haitao Zhao Ledu Zhou Wu Zhang Zhenyu Zhu Shukui Qin Feng Shen Xiujun Cai Gaojun Teng Jianqiang Cai Minshan Chen Qiang Li Lianxin Liu Weilin Wang Tingbo Liang Jiahong Dong Xiaoping Chen Xuehao Wang Shusen Zheng Jia Fan 无 | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 4 |
| 8 | Diatom-based reconstruction of Holocene environmental changes in Angren Lake,Southern Tibet显示文摘Based on the diatom analysis the climatic sequence between 11 000 and 6 000 aBP in Angren, southern Tibet is established, i.e. cold period (11 095-9 970 aBP)→temperate period (9 970-9 870 aBP)→Anathermal (9 870-9 770 aBP)→cool-dry period (9 770-8 740 aBP) →super-megathermal (8 740-8 590 aBP)→Megathermal (8 590-5 970 aBP). And the opinion that the reaction of diatom to temperature change is more sensitive than to other ecological factors has been pointed out and certified. | Shengfeng Li Fubao Wang Jie Zhang Xuhui Shen Zhaoqi Zeng | 1999 | Chinese Science Bulletin1999，44，12： | 3 |
| 9 | Wind power forecasting error-based dispatch method for wind farm cluster显示文摘With the technical development of wind power forecasting,making wind power generation schedule in power systems become an inevitable tendency.This paper proposes a new dispatch method for wind farm(WF)cluster by considering wind power forecasting errors.A probability distribution model of wind power forecasting errors and a mathematic expectation of the power shortage caused by forecasting errors are established.Then,the total mathematic expectation of power shortage from all WFs is minimized.Case study with respect to power dispatch in a WF cluster is conducted using forecasting and actual wind power data within 30 days from sites located at Gansu Province.Compared with the variable proportion method,the power shortage of the WF cluster caused by wind power forecasting errors is reduced.Along with the increment of wind power integrated into power systems,the method positively influences future wind power operation. | Ning CHEN Qi WANG Liangzhong YAO Lingzhi ZHU Yi TANG Fubao WU Mei CHEN Ningbo WANG | 2013 | Journal of Modern Power Systems and Clean Energy2013，1，1： | 3 |
| 10 | Effect of CO_(2)on coal P-wave velocity under triaxial stress显示文摘As P-wave velocity is sensitive to the variations in coal reservoir parameters,it is possible to monitor the injected CO_(2)through P-wave velocity during CO_(2)sequestration in coal.However,the effects of CO_(2)on the coal P-wave velocity under triaxial stress are not clearly discerned.In the present study,different boundary conditions and gases were utilised to investigate the factors affecting the P-wave velocity after the interaction of coal with CO_(2).Experiments with helium indicated that the pore pressure primarily affected the P-wave velocity by altering the effective stress.Experiments with CH4 and CO_(2)indicated that matrix swelling induced-cleats porosity decline significantly promoted P-wave velocity.Moreover,CO_(2)caused a wider scale and severe weakening of coal matrix than CH4,thereby significantly decreasing the P-wave velocity,and the decline in P-wave velocity increases with vitrinite content.Furthermore,experiments under different boundary conditions showed that with the boundary condition having more constraints,the decrement of pore pressure on P-wave velocity is more weaken,whereas the improvement of matrix swelling on P-wave velocity is more evident.This study contributes to understanding the mechanism of effect of CO_(2)on P-wave velocity under triaxial stress condition and provides guidance for monitoring CO_(2)sequestration in coal. | Shuangjiang Zhu Jianhong Kang Youpai Wang Fubao Zhou | 2022 | International Journal of Mining Science and Technology2022，32，1： | 3 |
| 11 | Application of three-phase foam to fight an extraordinarily serious coal mine fire显示文摘 | Fubao Zhou Wanxing Ren Deming Wang Tiliang Song Xiang Li Yuliang Zhang | 2005 | International Journal of Coal Geology2005，，1： | 2 |
| 12 | Real-Time Patient-Specific ECG Arrhythmia Detection by Quantum Genetic Algorithm of Least Squares Twin SVM显示文摘The automatic detection of cardiac arrhythmias through remote monitoring is still a challenging task since electrocardiograms(ECGs)are easily contaminated by physiological artifacts and external noises,and these morphological characteristics show significant variations for different patients.A fast patient-specific arrhythmia diagnosis classifier scheme is proposed,in which a wavelet adaptive threshold denoising is combined with quantum genetic algorithm(QAG)based on least squares twin support vector machine(LSTSVM).The wavelet adaptive threshold denoising is employed for noise reduction,and then morphological features combined with the timing interval features are extracted to evaluate the classifier.For each patient,an individual and fast classifier will be trained by common and patient-specific training data.Following the recommendations of the Association for the Advancements of Medical Instrumentation(AAMI),experimental results over the MIT-BIH arrhythmia benchmark database demonstrated that our proposed method achieved the average detection accuracy of 98.22%,99.65%and 99.41%for the abnormal,ventricular ectopic beats(VEBs)and supra-VEBs(SVEBs),respectively.Besides the detection accuracy,sensitivity and specificity,our proposed method consumes the less CPU running time compared with the other representative state of the art methods.It can be ported to Android based embedded system,henceforth suitable for a wearable device. | Duan Li Ruizheng Shi Ni Yao Fubao Zhu Ke Wang | 2020 | Journal of Beijing Institute of Technology2020，29，1： | 2 |
| 13 | Temperature dependent spectral response characteristic of Ⅲ-Ⅴ compound tandem cell显示文摘The GaInP/GaAs/Ge triple-junction tandem cells with a conversion efficiency of 27.1% were fabricated using metalorganic chemical vapor deposition (MOCVD) technique. Temperature dependence of the spectral response measurements of the GaInP/GaAs/Ge tandem cell was performed by a quantum effi- ciency system at temperatures ranging from 25℃ to 160℃. The red-shift phenomena of the absorption limit for all subcells were observed with increasing temperature, which is dued to the energy gap nar-rowing with temperature. The short-circuit current densities (Jsc) of GaInP, GaAs and Ge subcells at room temperature calculated based on the spectral response data were 12.9, 13.7 and 17 mA/cm2, re- spectively. The temperature coefficient of Jsc for the tandem cell was determined to be 8.9 μA/(cm2·℃), and the corresponding temperature coefficient of the open-circuit voltage deduced from the se- ries-connected model was -6.27 mV/℃. | LIU Lei CHEN NuoFu WANG Yu BAI YiMing CUI Min GAO FuBao | 2009 | Chinese Science Bulletin2009，54，3： | 2 |
| 14 | Positioning Systems and Algorithms for Wireless Sensor Network显示文摘 | Wang Fubao Shi Long Ren Fengyuan | 2004 | Journal of Software2004，16，5： | 1 |
| 15 | Application of three-phase foam to fight an extraordinarily serious coal mine fire显示文摘 | Zhou Fubao Ren Wanxing Wang Deming | | 0，，1： | 1 |
| 16 | Application of three-phase foam to fight an extraordinarily serious coal mine fire 显示文摘 | ZHOU Fubao REN Wanxing WANG Deming | 2006 | International Journal of Coal Geology2006，67，12： | 1 |
| 17 | Applica-tion of three-phase foam to fight an extraordinarily seri-ous coal mine fire显示文摘 | Fubao Zhou Wanxing Ren Deming Wang etl | 2006 | International Journal of Coal Geol-ogy2006，，95： | 1 |
| 18 | Numerical simulation of the flow field in cavitations nozzle for impinging streams reactor显示文摘 | Li Qin Wang Huilin Li Fubao | 2010 | Advanced Material Research2010，97，7： | 1 |
| 19 | Directory of recenttesting methods for coals to spontaneous combustion显示文摘 | Zhou Fubao Wang Deming | 2007 | Journal of Fire Sciences2007，22，2： | 1 |
| 20 | Climatic changes in the Qinghai-Xizang (Tibetan) region of China during the Holocene 显示文摘 | Wang Fubao | 1987 | Quaternary Research1987，28，4： | 1 |
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