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| 1 | Endovascular therapy for Acute ischemic Stroke Trial (EAST): study protocol for a prospective, multicentre control trial in China显示文摘Background and purpose:5 recent trials have shown the benefit of endovascular treatment for acute ischaemic stroke(AIS)due to large vessel occlusion of the anterior circulation.This study aims to evaluate the safety and efficacy of Solitaire thrombectomy in patients with moderate-to-severe stroke in the Chinese population,which has a high prevalence of intracranial atherosclerosis.Methods and analysis:This multicentre prospective control study will involve 17 stroke centres in China,and plans to recruit 150 patients in the intervention group,and 150 patients in the medical group,in which patients meet enrolment criteria but refuse intervention.Patients with AIS due to large vessel occlusion indicated for treatment with Solitaire stent retriever within 12 hours of symptom onset,and who meet the inclusion and exclusion criteria,will be enrolled in this study.The primary efficacy endpoint is functional independence as defined by a modified Rankin Scale(mRS)score≤2 at 90 days or by functional improvement as defined by mRS,using shift analysis.The procedural efficacy endpoint is arterial recanalisation of the occluded target vessel measured by a modified Thrombolysis in Cerebral Infarction(mTICI)score equal or superior to 2b right following the use of the study device.The primary safety endpoint is symptomatic intracranial haemorrhage(sICH)within 24±3 hours postprocedure.Ethics and dissemination:The protocol was approved by the Ethics Committee at the coordinating centre and by the local Institutional Review Board of each participating centre.Trial registration number:NCT02350283. | Zhongrong Miao Xiaochuan Huo Feng Gao Xiaoling Liao Chunjuan Wang Ya Peng Yibin Cao Shengli Chen Meng Zhang Changchun Jiang Xiaoxiang Peng Cunfeng Song Liping Wei Qiyi Zhu Zaiyu Guo Li Liu Hang Lin Hua Yang Wei Wu Hui Liang Anding Xu Kangning Chen Xingquan Zhao Yuesong Pan Hao Li Liping Liu Yilong Wang Yongjun Wang EAST investigators | 2016 | Stroke & Vascular Neurology2016，1，2： | 8 |
| 2 | Influence of Mo on the microstructure and mechanical properties of TiC-based cermets显示文摘The microstructures and mechanics properties of TiC-based cermets composed of TiC,WC,Ni,Co,Mo,and Cr3C2 were investigated.The results show that Mo has a great effect on the sintering densification,microstructures,and mechanical properties.The microstructures and distribution of Mo and Ti in the TiC-based cermets were analyzed.It was indicated that a new phase with Ti,Mo,W,and C was formed on the rim of(Ti,W)C grains by means of an addition of Mo into the TiC-based cermets.The new phase with a surrounding structure was of great aid to improve the wettability of the liquid phase on the solid phase surface of TiC,decrease the porosity and refine the grains of the hard phase,which gave rise to the increase in strength and hardness.The properties of the TiC-based cermets could be further improved to some extent by adding WC,Cr2C3,and Co. | WANG Xingqing,HE Xiaoxiang,and GUO Hailiang School of Materials Science and Engineering,Shanghai University,Shanghai 200072,China | 2010 | Rare Metals2010，29，4： | 5 |
| 3 | A five-fold pig bacterial artificial chromosome library:a resource for positional cloning and physical mapping显示文摘一个猪用绳子拖的平底渡船图书馆从一头 maleErhualian 猪与 genomic DNA 被构造。在有后部的 III 片 384 井盘子的部分消化以后(20 个盘子每超级水池) 。屏蔽系统的二拍子的圆舞 4 尺寸 PCR 被建立屏蔽积极克隆。一般水准插入 128 kb 的尺寸从 105 随机孤立的克隆被估计,它显示图书馆是超过五次 genomic 范围。为概率到的示范从图书馆选出任何唯一的基因或 DNA 标记, 10 单个拷贝的基因外面被屏蔽,积极克隆与 3.6 的一般水准在 1 和 8 之间被产出。积极超级水池为从猪染色体的不同区域选择的 32 个微卫星标记被获得。为每个标记的积极超级水池的数字与 4.78 的一般水准从 1 ~ 9 变化。这个用绳子拖的平底渡船图书馆为猪提供一个另外的资源物理印射和基因鉴定。 | LIU Wei ZHANG Ying LIU Zhaoliang GUO Li WANG Xiaobo FEI Jing FENG Jidong ZHAO Rui HU Xiaoxiang LI Ning | 2006 | Progress in Natural Science:Materials International2006，16，8： | 4 |
| 4 | Effect of Chaiqinchengqi decoction on inositol requiring enzyme 1α in alveolar macrophages of dogs with acute necrotising pancreatitis induced by sodium taurocholate显示文摘OBJECTIVE: To investigate the effect of Chaiqinchengqi decoction(CQCQD) on inositol requiring enzyme 1α(IRE1α) in alveolar macrophages(AMs)of the dog model of acute necrotising pancreatitis(ANP) induced by sodium taurocholate.METHODS: Fifteen beagle dogs were randomised into a control group,ANP group and CQCQD group(n = 5 per group). ANP was induced by a retrograde duct injection of 50 mg/kg of 5% sodium taurocholate. The dogs in the control group received injections of the same volume of saline as the sodium taurocholate. After the models were induced,the dogs in the CQCQD group were administered 10 m L/kg CQCQD every 2 h for 6 h. Two hours after the last administration of either CQCQD or saline,they were sacrificed by anaesthesia. AMs were collected to determine the IRE1α and Interleukin-1β(IL-1β)m RNA and protein expression,and pancreatic tissues were collected for histopathology analysis.RESULTS: Compared with the ANP group,the m RNA and protein expression of IRE1α and the protein expression of IL-1β of AMs in the CQCQD group were significantly down-regulated,and the pancreatic histopathology score of the CQCQD group also was lower. There was no significant difference in the m RNA expression of IL-1β of AMs between the two groups.CONCLUSION: The CQCQD-induced down-regulation of the IL-1β protein expression may involve the down-regulation of the m RNA and protein expression of IRE1α in AMs. | Guo Jia Wang Xiaoxiang Luo Ruijie Zhang Xiaoxin Yang Xiaonan Xia Qing Xue Ping | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 4 |
| 5 | Deep learning based user scheduling for massive MIMO downlink system显示文摘In this paper,we investigate a user scheduling algorithm for massive multiple-input multipleoutput(MIMO)systems over more general correlated Rician fading channels.To achieve low latency and high throughput,a new user scheduling algorithm based on deep learning(DL)is proposed,which exploits only statistical channel state information.The proposed scheduling network is trained to grasp the mapping from the statistical signal and interference pattern to the user scheduling decision through supervised learning.It can predict the optimal scheduling scheme from statistical CSI without iterative calculation after offline training.Simulation results demonstrate the superior performance of the proposed algorithm in terms of calculation time,and it achieves almost the same throughput as the optimal scheduling algorithm which is obtained through exhaustive search.Furthermore,with the normalization of the input data,the proposed scheduling network is robust to the change of the channel environment and the number of transmit antennas. | Xiaoxiang YU Jiajia GUO Xiao LI Shi JIN | 2021 | Science China(Information Sciences)2021，64，8： | 1 |
| 6 | Evolution of tumor microenvironment in colorectal liver metastases under treatment stress显示文摘Dear editor,The tumor microenvironment(TME)heavily impacts disease biology and may influence responses to systemic treatments,and thereby,affects patients’prognosis.In our previous study,we found that immune features could predict prognosis and guide the therapy choices for stage I-III colon cancer[1,2].Increasing evidence shows that therapyinduced TME changes can promote tumor progression,metastasis,and the development of resistance[3,4].However,the TME dynamics in colorectal liver metastases(CRLM)under treatment are still incompletely clear. | Na Huang Dongqiang Zeng Xiaoxiang Rong Chunlin Wang Zhenzhen Wu Jian Guo Yuqi Wang Jin Li Jing Li Jiao Wang Siting Zheng Genjie Huang Jianping Bin Yulin Liao Qian Li Xin Yi Wangjun Liao Min Shi | 2022 | Cancer Communications2022，42，5： | 1 |
| 7 | Effects ofnon - stoichiometry on the mechanical properties ofNd2 - xZr2 + xO7 + x /2ceramics显示文摘 | Zhang Yu Guo Lei Zhao Xiaoxiang | 2014 | Mterials Letters2014，136，： | 1 |
| 8 | Effect of Phase Structure Evolution on Thermal Expansion and Toughness of (Nd1-xScx)2Zr2O7 (x = 0, 0.025, 0.05, 0.075, 0.1 ) Ceramics显示文摘Nd_2Zr_2O_7 is being explored as an alternate thermal barrier coating(TBC) material for operating above1300 °C, and great effort has been made to enlarge its thermal expansion coefficient(TEC) and improve its toughness. In this study, Sc_2O_3 was doped to Nd_2Zr_2O_7. The phase structure, TECs and toughness of((Nd_(1-x)Scx))_2Zr_2_O7(x= 0, 0.025, 0.05, 0.075, 0.1) compounds were investigated.((Nd_(1-x)Scx))_2Zr_2_O7(x = 0, 0.025,0.05, 0.075) exhibited pyrochlore structure, while((Nd_(0.9)Sc_(0.1)))_2Zr_2O_7 consisted of pyrochlore and fluorite phases. With the increase of the Sc_2O_3 content, the ordering degree of the pyrochlore in the compounds decreased. In((Nd_(1-x)Scx))_2Zr_2O_7 series,((Nd_(0.925)Sc_(0.075)))_2Zr_2O_7 exhibited the largest TEC, while the toughness of the compounds increased with increasing the Sc_2O_3 content. The related mechanisms were discussed based on the crystal structure analysis. Considering the TEC and toughness, 10 mol% Sc_2O_3 was suggested as the optimal doping content for Nd_2Zr_2O_7 ceramic. | Xiaoxiang Zhao Lei Guo Caimei Wang Yu Zhang Fuxing Ye | 2017 | Journal of Materials Science & Technology2017，33，2： | 1 |
| 9 | The protective effect of MT-α-glucan against streptozotocin (STZ)-induced NIT-1 pancreatic β-cell damage显示文摘 | Lei Hong Wang Qin Guo Shuzhen Han Juncheng Sun Hanju Zhang Xiaoxiang Wu Wutong | 2013 | Carbohydrate Polymers2013，，2： | 1 |
| 10 | Design of a prediction system based on the dynamical feed-forward neural network显示文摘Analysis and prediction of time series play a significant role in scientific fields of meteorology,epidemiology,and economy.Efficient and accurate prediction of signals can give an early detection of abnormal variations,provide guidance on preparing a timely response and avoid presumably adverse impacts.In this paper,a prediction system is designed based on the dynamical feed-forward neural network.The trajectory information in the reconstructed phase space,which is topologically equivalent to the dynamical evolution of the system,is applied to establish the prediction model.Moreover,an integer constrained particle swarm optimization algorithm is employed to select the optimal time delay,which is the parameter of our system.Simulation results for applications on the Lorenz system,stock market index,and influenza data indicate that our proposed method can produce efficient and reliable predictions. | Xiaoxiang GUO Weimin HAN Jingli REN | 2023 | Science China(Information Sciences)2023，66，1： | 1 |
| 11 | Preventing autosomal-dominant hearing loss in Bth mice with CRISPR/CasRx-based RNA editing显示文摘CRISPR/RfxCas13d(CasRx)editing system can specifically and precisely cleave single-strand RNAs,which is a promising treatment for various disorders by downregulation of related gene expression.Here,we tested this RNA-editing approach on Beethoven(Bth)mice,an animal model for human DFNA36 due to a point mutation in Tmc1.We first screened 30 sgRNAs in cell cultures and found that CasRx with sgRNA3 reduced the Tmc1^(Bth)transcript by 90.8%,and the Tmc1 wild type transcript(Tmc1^(+))by 44.3%.We then injected a newly developed AAV vector(AAV-PHP.eB)based CasRx into the inner ears of neonatal Bth mice,and we found that Tmc1^(Bth)was reduced by 70.2%in 2 weeks with few off-target effects in the whole transcriptome.Consistently,we found improved hair cell survival,rescued hair bundle degeneration,and reduced mechanoelectrical transduction current.Importantly,the hearing performance,measured in both ABR and DPOAE thresholds,was improved significantly in all ages over 8 weeks.We,therefore,have validated the CRISPR/CasRx-based RNA editing strategy in treating autosomal-dominant hearing loss,paving way for its further application in many other hereditary diseases in hearing and beyond. | Ziwen Zheng Guo Li Chong Cui Fang Wang Xiaohan Wang Zhijiao Xu Huiping Guo Yuxin Chen Honghai Tang Daqi Wang Mingqian Huang Zheng-Yi Chen Xingxu Huang Huawei Li Geng-Lin Li Xiaoxiang Hu Yilai Shu | 2022 | Signal Transduction and Targeted Therapy2022，7，4： | 1 |
| 12 | LncRNA-Airn alleviates acute liver injury by inhibiting hepatocyte apoptosis via the NF-κB signaling pathway显示文摘Acute liver injury is a common and serious syndrome caused by multiple factors and unclear pathogenesis.If the injury persists,liver injury can lead to cirrhosis and liver failure and ultimately results in the development of liver cancer.Emerging evidence has indicated that long noncoding RNAs(lncRNAs)play an important role in the development of liver injury.However,the role of antisense Igf2r RNA(Airn)in acute liver injury and its underlying mechanism remain largely unclear.In this study,we show that Airn is upregulated in liver tissue and primary hepatocytes from an acute liver injury mouse model.Consistently,Airn is also overexpressed in serum samples of patients with acute-on-chronic liver failure and is negatively correlated with the Model for End-Stage Liver Disease(MELD)score.Moreover,gene knockout and rescue assays reveal that Airn alleviates CCl_(4)-induced liver injury by inhibiting hepatocyte apoptosis and oxidative stress in vivo.Further investigation reveals that Airn decreases H_(2)O_(2)-induced hepatocyte apoptosis in vitro.Mechanistically,we reveal that Airn represses CCl_(4)-and H_(2)O_(2)-induced enhancement of phosphorylation of p65 and IκBα,suggesting that Airn inhibits hepatocyte apoptosis by inactivating the NF-κB pathway.In conclusion,our results demonstrate that Airn can alleviate acute liver injury by inhibiting hepatocyte apoptosis via inactivating the NF-κB signaling pathway,and Airn could be a potential biomarker for acute liver injury. | Shuai Shao Yu Zhang Feng Zhou Xiaoxiang Meng Zhenjun Yu Guantong Li Lina Zheng Kun Zhang Yuhan Li Beichen Guo Qi Liu Mengxia Zhang Xiaoxiao Du Wei Hong Tao Han | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 1 |
| 13 | Organocatalytic dynamic kinetic resolution of N-arylindole lactams:atroposelective construction of axially chiral amino acids bearing a C–N chiral axis显示文摘Organocatalytic dynamic kinetic resolution of configurationally labile cyclic molecules represents one of the most efficient methods for the atroposelective construction of axially chiral molecules bearing a tetra-ortho-substituted chiral axis.Notably,this privileged strategy is limited to constructing a C–C chiral axis.Herein,organocatalytic dynamic kinetic resolution of configurationally labile N-arylindole lactams has been successfully achieved at the first time,allowing for access to a structurally diverse set of axially chiral N-arylindole amino esters with a tetra-ortho-substituted C–N chiral axis in excellent yields and atroposelectivities.In addition to the N-arylindole skeleton,N-aryl thieno[3,2-b]pyrrole,furo[3,2-b]pyrrole,and pyrrolo[2,3-b]pyridine skeletons are also compatible with this transformation.This transition-metal-free facile strategy features a broad substrate scope,mild reaction conditions,easy scale-up and excellent atom economy.Several potentially valuable molecules,such as axially chiral peptides,were efficiently generated from the resulting configurationally stable axially-chiral N-arylindole amino esters,demonstrating the power of this strategy. | Xianfang Hong Jingcheng Guo Jinhua Liu Wei Cao Chenlong Wei Ye Zhang Xiaoxiang Zhang Zhenqian Fu | 2022 | Science China Chemistry2022，65，5： | 0 |
| 14 | Correlation between jerky flow and jerky dynamics in a nanoscratch on a metallic glass film显示文摘Chaos has been well understood in dynamic system, however, how the chaotic behavior occur in jerky flow in material, is still not clear, and is lack of specific chaotic attractor. Here the jerky evolution of lateral force and the stair-like fluctuation of lateral displacement are observed for Ni62 Nb38(at.%) metallic glass film during nanoscratch process. This jerky flow is investigated by using the largest Lyapunov exponent, Kolmogorov entropy and fractal dimension, and chaotic behavior of lateral force-time and normal displacement-lateral displacement sequences is verified. In addition to time series analysis, it is found that jerk equation can be used to describe the jerky flow of the metallic-glass film during nanoscratch. More importantly, unambiguous chaotic attractor is presented by jerky dynamics using 'jerk'-singularities, namely the total change rate of lateral force relative to scratch time. These reveal an inner connection between jerky flow and jerky dynamics in nanoscratch of a metallic-glass film. | LiPing Yu DongXue Han JingLi Ren XiaoXiang Guo ShaoKang Guan Gang Wang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，7： | 0 |
| 15 | Immunosuppressive therapy selectively modulates B-cell responses in patients with rheumatic and musculoskeletal diseases receiving the inactivated COVID-19 vaccine显示文摘Background:Immunosuppressive medication reduces the immunogenicity of the coronavirus disease 2019(COVID-19)vaccines in patients with rheumatic and musculoskeletal diseases(RMDs).However,the underlying mechanism remains unclear.The primary aim of our study was to dissect the impact of immunosuppressive medication on cellular and humoral immune responses in RMD patients receiving the inactivated COVID-19 vaccine.Methods:A total of 28 RMD patients and five healthy controls(HCs)receiving two doses of the inactivated COVID-19 vaccine(Sinovac-CoronaVac)were prospectively enrolled.Blood samples were collected before the primary vaccination(Week 0)and one week after the second vaccination(Week 5).Neutralizing antibody(nAb)titers and autoantibody titers were measured by a pseudovirus-based neutralization assay and enzyme-linked immunosorbent assay,respectively.CD4^(+)T-cell and CD19^(+)B-cell subsets and serum cytokines were analyzed by flow cytometry.Results:The inactivated COVID-19 vaccine was immunogenic in RMD patients and HCs after the second vaccination,but the nAb titers were lower in RMD patients than those in HCs.Only patients with systemic lupus erythematosus(SLE)had notably increased nAb titers.Remarkably,IgG^(+)CD27^(+),IgG^(+)IgG1^(+),and IgG^(+)IgG1^(−)B cells were reduced,whereas IgG−IgG1^(+)B cells,and total IgA and IgG titers were markedly increased.However,Tfh cell and Tfr cell subsets and cytokines produced by Tfh cells were not increased.The flare rate was low in RMD patients with comparable autoantibody titers,unchanged CD4^(+)T cell subsets and serum proinflammatory cytokines(interleukin[IL]-6,IL-17,interferon-γ,and tumor necrosis factor-α)after the second vaccination.Conclusions:Immunosuppressive therapy decreased the immunogenicity of the vaccine and maintained a low flare rate by selectively modulating B cell but not CD4^(+)T cell responses in RMD patients receiving the inactivated COVID-19 vaccine.Optimization of the treatment regimen might ensure a durable and robust COVID-19 vaccination response. | Rui Li Ruru Guo Jia Li Bing Zheng Ronghao Xu Xiaoyue Jiang Yingying Chen Guo Tang Qianqian Li Yixuan Li Jiaqi Feng Xiaoxiang Chen Ying Wang Shuang Ye Fang Du Liangjing Lu Jun Deng | 2023 | Rheumatology & Autoimmunity2023，3，2： | 0 |
| 16 | Transcription-wide impact by RESCUE-induced off-target single-nucleotide variants in mammalian cells显示文摘RNA base editing is a promising tool in precise molecular therapy. Currently, there are two widely used RNA base editors, REPAIRand RESCUE. REPAIR only facilitates A-to-I conversions, while RESCUE performs both A-to-I and C-to-U conversions. Thus, RESCUEcan generate twice the number of mutations compared to REPAIR. However, transcription-wide impact due to RESCUE-induced offtarget single-nucleotide variants (SNVs) is not fully appreciated. Therefore, to determine the off-target effects of RESCUE-mediatedediting, we employed transcription-wide sequencing on cells edited by RESCUE. The SNVs showed different off-target effects onmRNA, circRNA, lncRNA, and miRNA expression patterns and their interacting networks. Our results illustrate the transcriptionwide impact of RESCUE-induced off-target SNVs and highlight the need for careful characterization of the off-target impact by thisediting platform. | Guo Li Xiaoning Zhu Yihan Wang Hongru Ma Yuzhe Wang Hanyu Wu Xiangyang Li Yiling Wang Jianen Gao Xuexin Chen Xingxu Huang Yuan Yao Xiaoxiang Hu | 2023 | Journal of Molecular Cell Biology2023，15，2： | 0 |
| 17 | Sparse identification-assisted exploration of the atomic-scale deformation mechanism in multiphase CoCrFeNi high-entropy alloys显示文摘This study investigated the atomic-scale deformation mechanism of multiphase CoCrFeNi high-entropy alloys(HEAs)at liquid helium,liquid nitrogen,and room temperatures.A million-atom multiphase HEA was prepared using molecular dynamics simulation involving melt and quench processes.The HEA exhibited high-density dislocations and some twins,consistent with experimental observations.Quantitative analysis revealed an inconsistent evolution of the microstructure under tensile deformation.In particular,the elastic and initial plastic stages exhibited an increase in the disordered structure at the expense of the face-centered cubic and hexagonal close-packed structures,followed by a subsequent transformation involving multiple structural rearrangements.Furthermore,through sparse identification,a model depicting microstructural evolution during tension was extracted for the CoCrFeNi HEA at three typical temperatures and three tensile rates.The model highlighted the importance of the body-centered cubic structure in the evolutionary process. | XIAO Lu GUO XiaoXiang SUN YuTong WANG Gang LONG WeiMin LIAW Peter K. REN JingLi | 2024 | Science China(Technological Sciences)2024，67，4： | 0 |
| 18 | Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulin μ heavy-chain transgenic mice显示文摘In this study,we introduced the bovine immunoglobulinμheavy-chain gene(the orphaned gene on BTA11)into mouse germline cells.Bovine IgM was highly expressed in selected transgenic lines,and it largely inhibited rearrangements of the endogenous immunoglobulin heavy chain(IgH)genes in these lines.The forced expression of bovine IgM resulted in reduced numbers of pro-and pre-B cells but increased the number of immature B cells in the transgenic mice.Bovine IgM-expressing B cells can migrate from the bone marrow to the spleen,but most of the cells are arrested at the T1 transitional B cell stage,leading to a significantly lower number of T2 transitional and mature B cells in the spleen.Although the serum concentrations of endogenous IgM and IgG in the transgenic mice were significantly decreased,the IgA levels were slightly increased compared to the WT mice.The bovine IgM level in the serum was only one-tenth to one-fifth of that of endogenous mouse IgM,suggesting that most of the serum immunoglobulin were contributed by endogenous IgH gene-expressing B cells.These transgenic mice also exhibited a lower frequency of unique complementarity determining region 3(CDR3)sequences in their VH repertoire and Vκrepertoire but exhibited an increased frequency of unique CDR3 in their Vλrepertoire.Compared to the WT mice,the transgenic mice had a significantly higher percentage of mouse IgMexpressing B cells that expressedλchains.Finally,we showed that the transgenic mice were deficient in a specific antibody response to antigen stimulation. | Min ZHANG Xueqian CHENG Dan CHU Jingwen LIANG Yi SUN Li MA Beilei XU Min ZHENG Meili WANG Liming REN Xiaoxiang HU Qingyong MENG Ran ZHANG Ying GUO Yunping DAI Robert AITKEN Ning LI Yaofeng ZHAO | 2014 | Frontiers of Agricultural Science and Engineering2014，1，2： | 0 |
| 19 | Extracting governing system for the plastic deformation of metallic glasses using machine learning显示文摘This paper shows hidden information from the plastic deformation of metallic glasses using machine learning.Ni_(62)Nb_(38)(at.%)metallic glass(MG)film and Zr_(64.13)Cu_(15.75)Al_(10)Ni_(10.12)(at.%)BMG,as two model materials,are considered for nano-scratching and compression experiment,respectively.The interconnectedness among variables is probed using correlation analysis.The evolvement mechanism and governing system of plastic deformation are explored by combining dynamical neural networks and sparse identification.The governing system has the same basis function for different experiments,and the coefficient error is≤0.14%under repeated experiments,revealing the intrinsic quality in metallic glasses.Furthermore,the governing system is conducted based on the preceding result to predict the deformation behavior.This shows that the prediction agrees well with the real value for the deformation process. | Liping Yu Xiaoxiang Guo Gang Wang Baoan Sun Dongxue Han Cun Chen Jingli Ren Weihua Wang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，6： | 0 |
| 20 | Genome-Wide Association Study for Milled Grain Appearance Traits Using Multi-Parent Advanced Generation Intercross Population in Rice显示文摘The identification of loci and markers associated with milled grain appearance traits is essential for breeding high-yielding and good-quality rice variety.To detect stable loci for these characteristics,grain length(GL),grain width(GW),grain length/width(GLW),chalkiness degree(CD),chalky-grain rate(CR)and translucency degree(TD)of 378 rice lines were evaluated in three seasons.These lines were derived from a multi-parent advanced generation intercross(MAGIC)population. | LI Xiaoxiang LIU Jindong GUO Liang WEI Xiucai WANG Yamei PAN Xiaowu DONG Zheng LIU Wenqiang LIU Licheng MIN Jun LIU Sanxiong YE Guoyou LI Yongchao | 2023 | Rice science2023，30，5： | 0 |
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