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| 1 | Expression of orphan nuclear receptor NR4A2 in gastric cancer cells confers chemoresistance and predicts an unfavorable postoperative survival of gastric cancer patients with chemotherapy显示文摘 | Yifang Han Hui Cai Liye Ma Yibo Ding Xiaojie Tan Wenjun Chang Wei Guan Yan Liu Qiuxia Shen Yongwei Yu Hongwei Zhang Guangwen Cao | 2013 | Cancer2013，，19： | 2 |
| 2 | Polymeric architectures of bismuth citrate based on dimeric building blocks显示文摘Four bismuth complexes, (H2En)[Bi2(cit)2(H2O)4/3]·(H2O)x (1), (H2En)3[Bi2(cit)2Cl4]·(H2O)x (2), (HPy)2[Bi2(cit)2(H2O)8/5]·(H2O)x (3) and (H2En)[Bi2(cit)2](H2O)x (4) [cit = citrate4-; En = ethylenediamine; Py = pyridine] have been synthesized and crystallized. The crystal structures reveal that the basic building blocks in all of these complexes are bismuth citrate dimeric units which combine to form polymeric architectures. The embedded protonated ethylenediamine and pyridine moieties in the polymeric frameworks have been identified by X-ray crystallography and solid-state cross polarization/magic angle spinning (CP/MAS) 13C NMR. Based on the framework of complex 1, a structural model of a clinically used antiulcer drug, ranitidine bismuth citrate (RBC) was generated. The behavior of the protonated amine-bismuth citrate complexes in acidic aqueous solution has been studied by electrospray ionization-mass spectrometry (ESI-MS). | YANG Nan AN Yan CAI JiWen HU LiHong ZENG YiBo MAO ZongWan CHEN GuanHua SUN HongZhe | 2010 | Science China Chemistry2010，53，10： | 1 |
| 3 | A joint call for actions to advance taxonomy in China显示文摘Taxonomy plays an important role in understanding the origin, evolution, and ecological functionality of biodiversity. There are large number of unknown species yet to be described by taxonomists, which together with their ecosystem services cannot be effectively protected prior to description. Despite this, taxonomy has been increasingly underrated insufficient funds and permanent positions to retain young talents. Further, the impact factordriven evaluation systems in China exacerbate this downward trend, so alternative evaluation metrics are urgently necessary. When the current generation of outstanding taxonomists retires,there will be too few remaining taxonomists left to train the next generation. In light of these challenges, all co-authors worked together on this paper to analyze the current situation of taxonomy and put out a joint call for immediate actions to advance taxonomy in China. | Chaodong Zhu Arong Luo Ming Bai Michael COrr Zhonge Hou Siqin Ge Jun Chen Yibo Hu Xuming Zhou Gexia Qiao Hongzhi Kong Limin Lu Xiaohua Jin Lei Cai Xinli Wei Ruilin Zhao Wei Miao Qingfeng Wang Zhongli Sha Qiang Lin Meng Qu Jianping Jiang Jiatang Li Jing Che Xuelong Jiang Xiaoyong Chen Lianming Gao Zongxin Ren Chunlei Xiang Shixiao Luo Donghui Wu Dong Liu Yanqiong Peng Tao Su Chenyang Cai Tianqi Zhu Wanzhi Cai Xingyue Liu Hu Li Huaijun Xue Zhen Ye Xuexin Chen Pu Tang Shujun Wei Hong Pang Qiang Xie Feng Zhang Feng Zhang Xianjin Peng Aibing Zhang Taiping Gao Changfa Zhou Chen Shao Libin Ma Zhaoming Wei Yunxia Luan Ziwei Yin Wu Dai Cong Wei Xiaolei Huang Jingxian Liu Xiangsheng Chen Tianci Yi Zhisheng Zhang Zhulidezi Aishan Qin Li Hongying Hu | 2022 | Zoological Systematics2022，47，3： | 1 |
| 4 | Remediation of Cu and As contaminated water and soil utilizing biochar supported layered double hydroxide:Mechanisms and soil environment altering显示文摘Preparing materials for simultaneous remediation of anionic and cationic heavy metals contamination has always been the focus of research. Herein a biochar supported FeMnMg layered double hydroxide(LDH) composites(LB) for simultaneous remediation of copper and arsenic contamination in water and soil has been assembled by a facile co-precipitation approach. Both adsorption isotherm and kinetics studies of heavy metals removal by LB were applied to look into the adsorption performance of adsorbents in water. Moreover, the adsorption mechanisms of Cu and As by LB were investigated, showing that Cu in aqueous solution was removed by the isomorphic substitution, precipitation and electrostatic adsorption while As was removed by complexation. In addition, the availability of Cu and As in the soil incubation experiments was reduced by 35.54%–63.00% and 8.39%–29.04%, respectively by using LB. Meanwhile, the addition of LB increased the activities of urease and sucrase by 93.78%–374.35% and 84.35%–520.04%, respectively, of which 1% of the dosage was the best. A phenomenon was found that the richness and structure of microbial community became vigorous within 1% dosage of LB, which indirectly enhanced the passivation and stabilization of heavy metals. These results indicated that the soil environment was significantly improved by LB. This research demonstrates that LB would be an imaginably forceful material for the remediation of anionic and cationic heavy metals in contaminated water and soil. | Pengling Shao Hua Yin Yingchao Li Yuhao Cai Caiya Yan Yibo Yuan Zhi Dang | 2023 | Journal of Environmental Sciences2023，，4： | 1 |
| 5 | Comparative risk of acute kidney injury among cancer patients treated with immune checkpoint inhibitors显示文摘With the development and introduction of immune checkpoint inhibitors(ICIs)in cancer patients,immune-related side effects have increasingly attracted attention.However,the risks of immune-related renal toxicity are poorly characterized.In this study,we performed a network meta-analysis(NMA)of ICI-related randomized clinical trials(RCTs)to elucidate the comparative risk of acute kidney injury(AKI)in cancer patients receiving different ICIs.We also sought to identify other factors potentially affecting the risk of AKI.PubMed and EMBASE were searched for peer-reviewed trial reports published between January 2000 and May 2021.Eligible studies were RCTs studying ICIs in cancer patients and reporting AKI data.We performed a frequentist NMA to evaluate the risk ratios for grade 1-5 and grade 3-5 AKI between the treatment groups.We also assessed the absolute incidence of AKI in the ICI-containing arm using traditional direct meta-analysis.Once significant heterogeneity was detected in a traditional direct meta-analysis,multivariable meta-regression analysis was applied to identify factors that significantly affected the absolute incidence of AKI.A total of 85 RCTs were included in this study.In the NMA for the risk of grade 1-5 and 3-5 AKI,ipilimumab showed a significantly higher risk than avelumab and durvalumab,whereas 1 mg/kg nivolumab plus 3 mg/kg ipilimumab(N1I3)showed a significantly higher risk than other groups.In terms of treatment ranking,durvalumab±low-dose tremelimumab and avelumab were consistently among the top three safest treatments for grade 1-5 or 3-5 AKI,whereas N1I3,ipilimumab and tremelimumab were consistently among the top three treatments with the highest risk for grade 1-5 or 3-5 AKI.Compared with other cancers,renal cell carcinoma and urothelial carcinoma showed a significantly higher risk of AKI.The incidence of AKI was significantly higher with ICI+chemotherapy than with ICI monotherapy.In this NMA involving largescale up-to-date ICI trials,we demonstrated the comparative safety of existing ICI drugs for grade 1-5 and grade 3-5 AKI.Based on data from the ICI arms of these trials,we also revealed several potential risk factors for immune-related AKI,including tumor type and treatment paradigm. | Fei Liu ZixianWang Xiaofan Li Zhen Zhang Yue Yang Junquan Chen Dinghua Chen Lingling Wu Xiangyu Liu Sujun Han Fangming Wang Wasilijiang Wahafu Yibo Gao Shancheng Ren Nianzeng Xing Guangyan Cai Xiangmei Chen | 2023 | Cancer Communications2023，43，2： | 1 |
| 6 | Turning gray selenium into a nanoaccelerator of tissue regeneration by PEG modification显示文摘Selenium(Se)is an essential trace element involved in nearly all human physiological processes but suffers from a narrow margin between benefit and toxicity.The nanoform of selenium has been proven shown to be more bioavailable and less toxic,yet significant challenges remain regarding the efficient and feasible synthesis of biologically active nanoselenium.In addition,although nanoselenium has shown a variety of biological activities,more interesting nanoselenium features are expected.In this work,hydrosoluble nanoselenium termed Nano-Se in the zero oxidation state was synthesized between gray Se and PEG.A zebrafish screen was carried out in zebrafish larvae cocultured with Nano-Se.Excitingly,Nano-Se promoted the action of the FGFR,Wnt,and VEGF signaling pathways,which play crucial roles in tissue regeneration.As expected,Nano-Se not only achieved the regeneration of zebrafish tail fins and mouse skin but also promoted the repair of skin in diabetic mice while maintaining a profitable safe profile.In brief,the Nano-Se reported here provided an efficient and feasible method for bioactive nanoselenium synthesis and not only expanded the application of nanoselenium to regenerative medicine but also likely reinvigorated efforts for discovering more peculiarunique biofunctions of nanoselenium in a great variety of human diseases. | Jieqiong Cao Yibo Zhang Peiguang Zhang Zilei Zhang Bihui Zhang Yanxian Feng Zhixin Li Yiqi Yang Qilin Meng Liu He Yulin Cai Zhenyu Wang Jie Li Xue Chen Hongwei Liu An Hong Wenjie Zheng Xiaojia Chen | 2022 | Bioactive Materials2022，7，9： | 0 |
| 7 | Wenzhou Website Ties Cultural Knots显示文摘If latest data is correct, there are about 680,890 Wenzhou natives now living as immigrants in 131 countries and regions across the world. Altogether, overseas Wenzhou communities operate 44 Chinese media and 60 plus Chinese schools. Restaurants and other businesses set up and operated by overseas Wenzhou natives are numerous. The data may sound dry and boring, but what they are and what they do overseas are actually serving as a bridge between Wenzhou and the world. | By Cai Yibo Qian Ruogu Xu Zhifang Cai Yibo | 2017 | 文化交流2017，，1： | 0 |
| 8 | Ferroelectricity in hBN intercalated double-layer graphene显示文摘Van der Waals(vdW)assembly of two-dimensional materials has long been recognized as a powerful tool for creating unique systems with properties that cannot be found in natural compounds[Nature 499,419(2013)].However,among the variety of vdW heterostructures and their various properties,only a few have revealed metallic and ferroelectric behaviour signatures[Sci.Adv.5,eaax5080(2019);Nature 560,336(2018)].Here we show ferroelectric semimetal made of double-gated double-layer graphene separated by an atomically thin crystal of hexagonal boron nitride.The structure demonstrates high room temperature mobility of the order of 10 m2·V^(−1)·s^(−1) and exhibits ambipolar switching in response to the external electric field.The observed hysteresis is reversible and persists above room temperature.Our fabrication method expands the family of ferroelectric vdW compounds and offers a promising route for developing novel phase-changing devices.A possible microscopic model of ferroelectricity is discussed. | Yibo Wang Siqi Jiang Jingkuan Xiao Xiaofan Cai Di Zhang Ping Wang Guodong Ma Yaqing Han Jiabei Huang Kenji Watanabe Takashi Taniguchi Yanfeng Guo Lei Wang Alexander S.Mayorov Geliang Yu | 2022 | Frontiers of physics2022，17，4： | 0 |
| 9 | Hazard Analysis and Primary Prevention and Treatment Report of Diseases and Pests in Export Blueberry Base in Majiang County显示文摘To fully understand occurrence and damage status of pests and diseases in export blueberry,systematic survey was conducted in Majiang export blueberry bases in Guizhou Province from 2012 to 2015. A total of 21 kinds of pests and diseases were found on blueberry,including 10 kinds of diseases and 11 kinds of pests. Comprehensive analysis of pests and diseases and their damage degree revealed that pests and diseases causing severe damage were gray mold,scarab and fruit fly,while gray mold and fruit fly might seriously affect the export of blueberry. The prevention and control measures against gray mold and fruit fly were summarized. | Wang Tao Ren Yanling Liao Jiongfeng Zhang Yi Wang Jiayin Yang Feng Wang Juan Wang Kejia Zhang Yibo Chen Xiao Wang Xingning Cai Qiu Xu Ning Ou Houding | 2016 | Plant Diseases and Pests2016，7，3： | 0 |
| 10 | Large scalable,ultrathin and self-cleaning cellulose aerogel film for daytime radiative cooling显示文摘Passive cooling strategy shows great potential in mitigating global warming and reducing energy consumption.Because of the high emissivity in the atmospheric transparency window(λ≈8–13μm),cellulose is considered as a good candidate for radiative cooling.However,traditional cellulose coolers generally show poor solar reflection and can be polluted by dust outside,thereby resulting in poor daytime cooling efficiency.To address these drawbacks,we developed sustainable cellulose nanowhiskers(CNWs)/ZnO composite aerogel films with favorable optical performance,mechanical robustness,and self-cleaning function for efficient daytime radiative cooling,which can be achieved via freeze casting and hot-pressing process.Due to formation of multi-level porous structure and chemical bonds(Si-O-C/Si-O-Si),such aerogel film exhibited high solar reflectance(97%)and high infrared emittance(92.5%).It achieved a sub-ambient temperature drop of 6.9℃under direct sunlight in hot weather.Most importantly,the surface roughness and low surface energy enable cellulose aerogel film hydrophobicity(contact angle=133°),thereby resulting in an anti-dust function.This work provides insight into the design of sustainable thermal regulating materials to realize carbon neutrality. | Chenyang Cai Yuanbo Sun Yi Chen Zechang Wei Yibo Wang Fuling Chen Wanquan Cai Jiawen Ji Yuxin Ji Yu Fu | 2023 | Journal of Bioresources and Bioproducts2023，8，4： | 0 |
| 11 | Deep Drilling Campaign in the Western Qaidam Basin,NE Tibetan Plateau and their Revealed Global Temperature Forcing of Salt Formation in the Late Miocene-Quaternary显示文摘The Qaidam Basin in the NE Tibetan Plateau has contributed the largest amount of potash in China.However,how the potash was formed has long been a subject of debate.Here we carried out a deep | FANG Xiaomin LI Minghui Erwin APPEL WANG Jiuyi HAN Wenxia ZHANG Weilin YANG Yibo CAI Maotang | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
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