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| 1 | De novo characterization of the root transcriptome of a traditional Chinese medicinal plant Polygonum cuspidatum显示文摘Various active components have been extracted from the root of Polygonum cuspidatum.However,the genetic basis for their activity is virtually unknown.In this study,25600002 short reads (2.3 Gb) of P.cuspidatum root transcriptome were obtained via Illumina HiSeq 2000 sequencing.A total of 86418 unigenes were assembled de novo and annotated.Twelve,18,60 and 54 unigenes were respectively mapped to the mevalonic acid (MVA),methyl-D-erythritol 4-phosphate (MEP),shikimate and resveratrol biosynthesis pathways,suggesting that they are involved in the biosynthesis of pharmaceutically important anthraquinone and resveratrol.Eighteen potential UDP-glycosyltransferase unigenes were identified as the candidates most likely to be involved in the biosynthesis of glycosides of secondary metabolites.Identification of relevant genes could be important in eventually increasing the yields of the medicinally useful constituents of the P.cuspidatum root.From the previously published transcriptome data of 19 non-model plant taxa,1127 shared orthologs were identified and characterized.This information will be very useful for future functional,phylogenetic and evolutionary studies of these plants. | HAO DaCheng MA Pei MU Jun CHEN ShiLin XIAO PeiGen PENG Yong HUO Li XU LiJia SUN Chao | 2012 | Science China(Life Sciences)2012，55，5： | 36 |
| 2 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 3 | High salt primes a specific activation state of macrophages, M(Na)显示文摘 | Wu-Chang Zhang Xiao-Jun Zheng Lin-Juan Du Jian-Yong Sun Zhu-Xia Shen Chaoji Shi Shuyang Sun Zhiyuan Zhang Xiao-qing Chen Mu Qin Xu Liu Jun Tao Lijun Jia Heng-yu Fan Bin Zhou Ying Yu Hao Ying Lijian Hui Xiaolong Liu Xianghua Yi Xiaojing Liu Lanjing Zhang Sheng-Zhong Duan | 2015 | Cell Research2015，25，8： | 15 |
| 4 | Astragaloside Ⅳ inhibits pathological functions of gastric cancer-associated fibroblasts显示文摘AIM To investigate the inhibitory effect of astragaloside IV on the pathological functions of cancer-associated fibroblasts,and to explore the underlying mechanism.METHODS Paired gastric normal fibroblast(GNF) and gastric cancer-associated fibroblast(GCAF) cultures were established from resected tissues. GCAFs were treated with vehicle control or different concentrations of astragaloside Ⅳ. Conditioned media were prepared from GNFs,GCAFs,control-treated GCAFs,and astragaloside Ⅳ-treated GCAFs,and used to culture BGC-823 human gastric cancer cells. Proliferation,migration and invasion capacities of BGC-823 cells were determined by MTT,wound healing,and Transwell invasion assays,respectively. The action mechanism of astragaloside Ⅳ was investigated by detecting the expression of micro RNAs and the expression and secretion of the oncogenic factor,macrophage colonystimulating factor(M-CSF),and the tumor suppressive factor,tissue inhibitor of metalloproteinase 2(TIMP2),in different groups of GCAFs. The expression of the oncogenic pluripotency factors SOX2 and NANOG in BGC-823 cells cultured with different conditioned media was also examined.RESULTS GCAFs displayed higher capacities to induce BGC-823 cell proliferation,migration,and invasion than GNFs(P < 0.01). Astragaloside Ⅳ treatment strongly inhibited the proliferation-,migration-and invasion-promoting capacities of GCAFs(P < 0.05 for 10 μmol/L,P < 0.01 for 20 μmol/L and 40 μmol/L). Compared with GNFs,GCAFs expressed a lower level of micro RNA-214(P < 0.01) and a higher level of micro RNA-301 a(P < 0.01). Astragaloside Ⅳ treatment significantly upregulated micro RNA-214 expression(P < 0.01) and down-regulated micro RNA-301 a expression(P < 0.01) in GCAFs. Reestablishing the micro RNA expression balance subsequently suppressed M-CSF production(P < 0.01) and secretion(P < 0.05),and elevated TIMP2 production(P < 0.01) and secretion(P < 0.05). Consequently,the ability of GCAFs to increase SOX2 and NANOG expression in BGC-823 cells was abolished by astragaloside Ⅳ.CONCLUSION Astragaloside Ⅳ can inhibit the pathological functions of GCAFs by correcting their dysregulation of micro RNA expression,and it is promisingly a potent therapeutic agent regulating tumor microenvironment. | Zhen-Fei Wang Da-Guang Ma Zhe Zhu Yong-Ping Mu Yong-Yan Yang Li Feng Hao Yang Jun-Qing Liang Yong-Yan Liu Li Liu Hai-Wen Lu | 2017 | World Journal of Gastroenterology2017，23，48： | 15 |
| 5 | Abating transport GHG emissions by hydrogen fuel cell vehicles: Chances for the developing world显示文摘 | Han HAO Zhexuan MU Zongwei LIU Fuquan ZHAO | 2018 | Frontiers in Energy2018，12，3： | 12 |
| 6 | Catalytic oxidation of benzene over nanostructured porous Co_3O_4-CeO_2 composite catalysts显示文摘Mesostructured Co3O4-CeO2 composite was found to be an effective catalytic material for the complete oxidation of benzene. The Co3O4-CeO2 catalysts with different Co/Ce ratios (mol/mol) were prepared via the nanocasting method and the mesostructure was replicated from two-dimensional (2D) hexagonal SBA-15 and three-dimensional (3D) cubic KIT-6 silicas, respectively. All the obtained Co3O4-CeO2 catalysts exhibited the similar symmetry with the parent silicas and well ordered mesostructures. The Co3O4- CeO2 catalysts with 2D mesostructure showed lower catalytic activities than the corresponding 3D materials. The Co3O4-CeO2 catalyst nanocasted from KIT-6 and with the Co/Ce ratio of 16/1 possessed the best catalytic benzene oxidation activity due to larger quantities of surface hydroxyl groups and surface oxygenated species. The mesostructured Co3O4-CeO2 material thus shows great potential as a promising eco-environmental catalyst for benzene effective elimination. | Chunyan Ma Zhen Mu Chi He Peng Li Jinjun Li Zhengping Hao | 2011 | Journal of Environmental Sciences2011，23，12： | 9 |
| 7 | Management and outcome of pelvic fractures in elderly patients: a retrospective study of 40 cases显示文摘 | Dong Jinlei Hao Wei Wang Bomin Wang Lubo Li Lianxin Mu Weidong Yang Yongliang Xin Maoyuan Wang Fu Zhou Dongsheng | 2014 | Chinese Medical Journal2014，，15： | 8 |
| 8 | Newborn screening with targeted sequencing:a multicenter investigation and a pilot clinical study in China显示文摘Different newborn screening(NBS) programs have been practiced in many countries since the 1960 s. It is of considerable interest whether next-generation sequencing is applicable in NBS. We have developed a panel of 465 causative genes for 596 early-onset, relatively high incidence, and potentially actionable severe inherited diseases in our Newborn Screening with Targeted Sequencing(NESTS) program to screen 11,484 babies in 8 Women and Children’s hospitals nationwide in China retrospectively. The positive rate from preliminary screening of NESTS was 7.85%(902/11,484). With 45.89%(414/902) follow-up of preliminary positive cases, the overall clinically confirmative diagnosis rate of monogenic disorders was 12.07%(50/414), estimating an average of 0.95%(7.85% × 12.07%) clinical diagnosis rate, suggesting that monogenic disorders account for a considerable proportion of birth defects. The disease/gene spectrum varied in different regions of China. NESTS was implemented in a hospital by screening 3923 newborns to evaluate its clinical application. The turn-around time of a primary report, including the sequencing period of < 7 days, was within 11 days by our automatic interpretation pipeline. Our results suggest that NESTS is feasible and cost-effective as a first-tier NBS program, which will change the status of current clinical practice of NBS in China. | Chanjuan Hao Ruolan Guo Xuyun Hu Zhan Qi Qi Guo Xuanshi Liu Yuanhu Liu Yanhua Sun Xiaofen Zhang Feng Jin Xiujie Wu Ren Cai Dingyuan Zeng Xijiang Hu Xiaohua Wang Xiaoping Ji Wenjie Li Quansheng Xing Lanfang Mu Xiulian Jiang Xue Yang Weimin Yang Yan Zhang Qianli Yin Xin Ni Wei Li | 2022 | Journal of Genetics and Genomics2022，49，1： | 7 |
| 9 | Stress spatial evolution law and rockburst danger induced by coal mining in fault zone显示文摘In order to explore the influence of coal mining disturbance on the rockburst occurring in fault zone, this research constructed a mechanical model for the evolution of fault stress, and analyzed the influence of the ratio of horizontal stress to vertical stress on the stability of fault, and the spatial distribution of the stress in fault zone as well as its evolution rule. Furthermore, the rockburst danger at different spatial areas of fault zone was predicated. Results show that: when both sides of the working face are mined out, the fault zone in the working face presents greater horizontal and vertical stresses at its boundaries but exhibits smaller stresses in its middle section; however, the ratio of horizontal stress to vertical stress is found to be greater at middle section and smaller at boundaries. As the working face advances towards the fault, the horizontal and vertical stresses of the fault firstly increases and then decreases; conversely,the ratio of horizontal stress to vertical stress keeps decreasing all the time. Therefore, if the fault zones are closer to the goaf and the coal wall, the stress ratio will be smaller, and the fault slip will be more prone to occur, therefore rockburst danger will be greater. This research results provide guidance for the rockburst prevention and hazard control of the coal mining in fault zone. | Li Teng Mu Zonglong Liu Guangjian Du Junliu Lu Hao | 2016 | International Journal of Mining Science and Technology2016，26，3： | 7 |
| 10 | Effect of tin addition on corrosion behavior of a low-alloy steel in simulated costal-industrial atmosphere显示文摘The effect of tin addition on the atmospheric corrosion behavior of a low-alloy steel in sim ulated coastalindustrial atm osphere has been investigated by indoor wet/dry cyclic corrosion test (CCT). The results indicate that tin addition can obviously make the steel substrate more resistant to atmospheric corrosion by suppressing the cathodic H^+ reduction reaction, and but tin addition is not of obvious beneficial effect when the steel is covered with a thicker rust layer during long-term corrosion process. The reason lies in the fact that the presence of un-reduced H^+ can lower the electrolyte pH value and lead to a loose and porous rust layer on tin-containing steel sample than that on tin-free steel sample. In addition, the 120 CCT cycles corrosion process of the two steels can be divided into three stages. Both the tin-free and tin-containing steels show an increasing corrosion rate during the initial corrosion stage and then exhibit a decreasing corrosion rate during the second and third corrosion stages. Moreover, tin addition makes the tin-containing steel rust layer have a higher amount of α-FeOOH and lower am ount of γ-FeOOH and Fe3O4 than the tin-free steel rust layer. | Bo Liu Xin Mu Ying Yang Long Hao Xueyong Ding Junhua Dong Zhe Zhang Huaxing Hou Wei Ke | 2019 | Journal of Materials Science & Technology2019，35，7： | 6 |
| 11 | Space Flight Validation of Design and Engineering of the ZDPS-1A Pico-satellite显示文摘The ZDPS-1A pico-satellites are the first satellites in China within the 1-10 kg mass range that are successfully operated on orbit. Unlike common pico-satellites, they are designed to be 'larger but stronger' with more powerful platforms and unique payloads so as to bear a better promise for real applications. Through their space flight mission, the functionality and performance of the two flight models are tested on orbit and validated to be mostly normal and in consistency with design and ground tests with only several inconforming occasions. Moreover, they have worked properly on orbit for one year so far, well exceeding their life expectancy of three months. Therefore, the space flight mission has reached all its goals, and verified that the design concept and the engineering process of the picosatellites are sufficient in allowing them the desired functionality and performance in, and the adaption to the launch procedure and the low-Earth orbit space environment. In the foreseeable future, the platform together with the design concept and the engineering process of the pico-satellites are expected to be applied to more complicated real space applications. | YANG Mu WANG Hao WU Changju WANG Chunhui DING Licong ZHENG Yangming JIN Zhonghe | 2012 | Chinese Journal of Aeronautics2012，25，5： | 5 |
| 12 | Co-Estimation of State of Charge and Capacity for Lithium-Ion Batteries with Multi-Stage Model Fusion Method显示文摘Lithium-ion batteries(LIBs)have emerged as the preferred energy storage systems for various types of electric transports,including electric vehicles,electric boats,electric trains,and electric airplanes.The energy management of LIBs in electric transports for all-climate and long-life operation requires the accurate estimation of state of charge(SOC)and capacity in real-time.This study proposes a multistage model fusion algorithm to co-estimate SOC and capacity.Firstly,based on the assumption of a normal distribution,the mean and variance of the residual error from the model at different ageing levels are used to calculate the weight for the establishment of a fusion model with stable parameters.Secondly,a differential error gain with forward-looking ability is introduced into a proportional–integral observer(PIO)to accelerate convergence speed.Thirdly,a fusion algorithm is developed by combining a multistage model and proportional–integral–differential observer(PIDO)to co-estimate SOC and capacity under a complex application environment.Fourthly,the convergence and anti-noise performance of the fusion algorithm are discussed.Finally,the hardware-in-the-loop platform is set up to verify the performance of the fusion algorithm.The validation results of different aged LIBs over a wide range of temperature show that the presented fusion algorithm can realize a high-accuracy estimation of SOC and capacity with the relative errors within 2%and 3.3%,respectively. | Rui Xiong Ju Wang Weixiang Shen Jinpeng Tian Hao Mu | 2021 | Engineering2021，7，10： | 5 |
| 13 | Toward emerging gallium oxide semiconductors:A roadmap显示文摘Owing to the advantages of ultra-wide bandgap and rich material systems,gallium oxide(Ga_(2)O_(3))has emerged as a highly viable semiconductor material for new researches.This article mainly focuses on the growth processes,material characteristics,and applications of Ga_(2)O_(3).Compared with single crystals and the epitaxial growth of other wide-bandgap semiconductors,large-size and high-quality��-Ga_(2)O_(3) single crystals can be efficiently grown with a low cost,making them highly competitive.Thanks to the availability of high-quality single crystals,epi-taxial films,and rich material systems,high-performance semiconductor devices based on Ga_(2)O_(3) go through a booming development in recent years.The defects and interfaces of Ga_(2)O_(3) are comprehensively analyzed owing to their significant influence on practical applications.In this study,the two most common applications of Ga_(2)O_(3) materials are introduced.The high breakdown electric field,high working temperature,and excellent Baliga’s figure-of-merit of Ga_(2)O_(3) represent an inspiring prospect for power electronic devices.In addition,the excellent absorption in deep-ultraviolet band provides new ideas for optoelectronic detectors and ensures the dramatic progress.Finally,the summary,challenges,and prospects of the Ga_(2)O_(3) materials and devices are presented and discussed. | Yuan Yuan Weibing Hao Wenxiang Mu Zhengpeng Wang Xuanhu Chen Qi Liu Guangwei Xu Chenlu Wang Hong Zhou Yanni Zou Xiaolong Zhao Zhitai Jia Jiandong Ye Jincheng Zhang Shibing Long Xutang Tao Rong Zhang Yue Hao | 2021 | Fundamental Research2021，1，6： | 5 |
| 14 | Pharmacological activation of REV-ERBα represses LPSinduced microglial activation through the NF-κB pathway显示文摘REV-ERBα,the NR1D1 (nuclear receptor subfamily 1,group D,member 1)gene product,is a dominant transcriptional silencer that represses the expression of genes involved in numerous physiological functions,including circadian rhythm,inflammation,and metabolism,ahd plays a crucial role in maintaining immune fdnctions. Microglia-mediated neuroinfiammation is tightly associated with various neurodegeneratiye diseases and psychiatricdisorders.However,the role of REV-ERBa in neuroinflammation is largely unclear.In this study,we investigated whether and how pharmacological activation of REV-ERBa affected lipopolysaccharide (LPS)-induced neuroinflammation inmouse microglia in vitro and in vivo.In BV2 cells or primary mouse culturedmicroglia,application of REV-ERBa agonist GSK4112 or SR9011 dose-dependently suppressed LPS-induced microglial activation through the'nuclear factor kappa B (NF-κB)pathway,in BV2 cells,pretreatment with GSK4112 inhibited LPS-induced phosphorylation of the inhibitor of NF-κB alpha (lkBα).kinase (IKK), thus restraining the pbosphorylation and degradation of IKBa,and blocked the nuclear translocation of p65,a NF-κB subunit,thereby suppressing the expression and secretion of the proinflammatory cytokines,such as interleukin 6 (IL- 6)and tumor necrosis factor a (TNFα).Moreover,REV-ERBα agonist-induced inhibi.tion on neuroinflammation protected neurons from microglial activatiOn-induced damage,whichwere also demonstrated in mice with their.ventral midbrain microiniected with GSK4112,and then stimulated with LPS.Our results reveal that enhanced REV-ERBα activity suppresses microglial activation through the NF-κB .pathway in the central nervous system. | Dong-kai Guo Yao Zhu Hong-yang Sun Xing-yun Xu Shun Zhang Zong-bing Hao Guang-hui Wang Chen-chen Mu Hai-gang Ren | 2019 | Acta Pharmacologica Sinica2019，40，1： | 5 |
| 15 | Low-frequency damping behavior of closed-cell Mg alloy foams reinforced with SiC particles显示文摘The damping properties of an Mg alloy foam and its composite foams were investigated using a dynamic mechanical thermal analyzer. The results show that the loss factors of both the Mg alloy and its composite foams are insensitive to temperature and loading frequency when the temperature is less than a critical temperature Tcrit. However, it increases when the temperature exceeds the Tcrit values, which are 200 and 250°C for the Mg alloy foam and the Mg alloy/SiCp composite foams, respectively. The Mg alloy/SiCp composite foams exhibit a higher damping capacity than the Mg alloy foam when the temperature is below 200°C. By contrast, the Mg alloy foam exhibits a better damping capacity when the temperature exceeds 250°C. The variation in the damping capacity is attributed to differences in the internal friction sources, such as the characteristics of the matrix material, abundant interfaces, and interfacial slipping caused by SiC particles, as well as to macrodefects in the Mg alloy and its composite foams. | Wen-zhan Huang Hong-jie Luo Yong-liang Mu Hao Lin Hao Du | 2017 | International Journal of Minerals,Metallurgy and Materials2017，24，6： | 5 |
| 16 | Genetic variation of Ardisia crenata in south China revealed by nuclear microsatellite显示文摘Ardisia crenata Sims,one of the most widely distributed Ardisia in the world,is an important ornamental and medicinal plant species.Using seven polymorphic nuclear microsatellite loci,we studied the genetic variation of 20 natural populations of A.crenata across its distribution center in south China.Significant deviation from the Hardy–Weinberg equilibrium in all populations and at all loci were detected,and the fixation index was high (FIS=0.725),indicating that inbreeding may be dominant in the mixed mating system of this self-compatible species.The average genetic diversity within populations was relatively low(HS=0.321).There was significant genetic differentiation among populations(FST=0.583),which may have resulted from a high level of inbreeding and a low level of gene flow.Ardisia crenata in south China can be roughly divided into an eastern group and a western group,consistent with the floristic division of the Sino-Himalayan forest subkingdom and the Sino-Japanese forest subkingdom.There may be separated glacial refugia in each region. | Hong-Ping MU Lan HONG Hong-Lin CAO Zheng-Feng WANG Zhong-Chao LI Hao SHEN Zhang-Ming WANG Wan-Hui YE | 2010 | Journal of Systematics and Evolution2010，48，4： | 4 |
| 17 | The design of monitoring communication system Based on Power line carrier显示文摘The design of the power line carrier communication system was introduced in this paper,DSP was adopted as the hardware platform to complete the core task.DSP sending terminal delivered the collecting data to the DSP receiving terminal through the power line carrier, and the DSP receiving terminal send the data to PC through a serial port.The design improved the power line carrier communication system and the data transmission became faster and more reliable.The experiment results showed that the PER of the receiving data is less than 0.4%, which satisfied the power line carrier communication requirement Our design is feasible and effective. | Wei-tao MU,Jian-jun HAO,Ping-xiang JIANG,Guo-wei LI (College of Information and Electrical Engineering,Shandong University of Science and Technology,qingdao266510,China) | 2010 | Journal of Measurement Science and Instrumentation2010，1，S1： | 4 |
| 18 | Active sites in CO2 hydrogenation over confined VOx-Rh catalysts显示文摘Metal oxide-promoted Rh-based catalysts have been widely used for CO2 hydrogenation,especially for the ethanol synthesis.However,this reaction usually suffers low CO2 conversion and alcohols selectivity due to the formation of byproducts methane and CO.This paper describes an efficient vanadium oxide promoted Rh-based catalysts confined in mesopore MCM-41.The Rh-0.3VO/MCM-41 catalyst shows superior conversion(〜12%)and ethanol selectivity(〜24%)for CO2 hydrogenation.The promoting effect can be attributed to the synergism of high Rh dispersion by the confinement effect of MCM-41 and the formation of VOr-Rh interface sites.Experimental and theoretical results indicate the formation of til-CO at VOv-Rh interface sites is easily dissociated into*CH X,and then*CH X can be inserted by CO to form CH3,*CO followed by CH3*CO hydrogenation to ethanol. | Guishuo Wang Ran Luo Chengsheng Yang Jimin Song Chuanye Xiong Hao Tian Zhi-Jian Zhao Rentao Mu Jinlong Gong | 2019 | Science China Chemistry2019，62，12： | 4 |
| 19 | Differentiation of a Miniature Inverted Transposable Element (MITE) System in Asian Rice Cultivars and Its Inference for a Diphyletic Origin of Two Subspecies of Asian Cultivated Rice显示文摘在现在的学习,我们在在亚洲栽培米饭(Oryza sativa L.) 的 102 个变化作为 mPing 知道的一个缩小的转换 TransposableElement (螨) 系统上报导调查。我们发现 mPing 人口能被概括进二个家庭, mPing-1 和 mPing-2,根据他们的顺序结构。进一步的分析证明 mPing 的这二个家庭在米饭的二亚种在他们的分发模式有重要偏爱,也就是 O。sativa ssp.japonica 和 indica。O。sativa 装饰用的梨树作为一个一般特点有 mPing-1 的一个更高的比例,而 O。sativa indica 有 mPing-2 的一个更高的比例。我们也在一个加倍的单倍体(DH ) 检验了 mPing 系统 jingxi 的跨 breeding 人口 17 (装饰用的梨树) 并且 zhaiyeqing 8 (indica ) 变化并且观察到 mPing 系统紧没被连接到主要 subspecies-determininggenes。而且,我们在亚洲普通野米饭 O.rufipogon 的 28 就职检查了 mPing 系统并且在 O 发现了 mPing 系统。rufipogon。在 O 的 mPing 系统的分发模式。rufipogon 显示亚洲人的来自二个祖先的起源栽培了米饭 O。sativa 种类。我们没在另一 20 Oryza 种类发现 mPing 系统。这些结果证实了一个以前的假设那 O。rufipogon 和 O。nivara 种类是 O 的近亲。sativa 并且 O 的二现存亚种。sativa 从 O.rufipogon 的相应生态型独立地被发展…… | Hao Hu Jie Mu Hong-Ji Zhang Yue-Zhi Tao Bin Han | 2006 | Journal of Integrative Plant Biology2006，48，3： | 4 |
| 20 | eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses显示文摘It has become increasingly challenging for researchers to analyze the exponentially expanding amount of multi-omic data.Here,we describe multi-functional software named evolutionary GenotypePhenotype Systems(eGPS)that enables users to perform comprehensive multiomic and evolutionary analyses.The eGPS combines the power of cloud computing and the advantage of desktop application,has a user-friendly graphic interface and is highly interactive. | Dalang Yu Lili Dong Fangqi Yan Hailong Mu Bixia Tang Xiao Yang Tao Zeng Qing Zhou Feng Gao Zhonghuang Wang Ziqian Hao Hongen Kang Yi Zheng Hongwei Huang Yuzhang Wei Wei Pan Yaochen Xu Junwei Zhu Shilei Zhao Ciran Wang Pengyu Wang Long Dai Mushan Li Li Lan Yiwei Wang Hua Chen Yi-Xue Li Yun-Xin Fu Zhen Shao Yiming Bao Fangqing Zhao Luo-Nan Chen Guo-Qing Zhang Wenming Zhao Haipeng Li | 2019 | National Science Review2019，6，5： | 4 |
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