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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Carbon-based perovskite solar cells: From single-junction to modules显示文摘Perovskite solar cells(PSCs)have attracted more and more attention in the scientific community due to their high performance and simple fabrication process.In the past few years,emerging technologies have made manufacturing large-scale PSC modules possible.However,stability and fabrication issues still limit the modularization and commercialization of PSCs.Carbon materials have been widely used in PSCs to overcome these challenges due to their excellent optical,electrical,and mechanical properties.In addition,the hydrophobic properties of certain carbon materials are highly effective at protecting the perovskite film from moisture and improving the stability of PSCs.All these superior properties have made carbon one of the most promising materials to fabricate future highperformance PSC modules with long service lifetimes.In this review,recent developments of carbon-based materials in different layers of single-junction PSCs will first be discussed,with an emphasis on functionalities related to PSCs’stability and modularization.Then,current improvements and future discussions in the manufacturing of monolithic PSC modules will be reviewed in detail. | Rui He Xiaozhou Huang Mason Chee Feng Hao Pei Dong | 2019 | Carbon Energy2019，1，1： | 6 |
| 3 | Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B显示文摘作为克积极的、形成孢子的厌氧的杆菌, Clostridium 顽固(C。顽固) 为严重、致命的 pseudomembranous 大肠炎负责,并且形成世界范围的最迫切的抗菌素抵抗威胁。流行 C。顽固全球性是联系抗菌素的腹泻的领先的原因,特别由于 hypervirulent 的出现,种类与高死亡和病态联系了的腹泻。TcdB,关键毒力因素之一由这个细菌藏匿了,通过糟糕理解的机制进入主人房间得到它的病原的效果。这里,我们报导 TcdB 细胞的受体的第一鉴定, chondroitin 硫酸盐 proteoglycan 4 (CSPG4 ) 。CSPG4 开始从屏蔽的一个整个染色体的人的 shRNAmir 图书馆被孤立,并且它的角色被证实由调停 TALEN 并且在人的房间的 CRISPR/Cas9-mediated 基因大美人。CSPG4 为对房间表面有约束力的 TcdB 是批评的,导致细胞骨架混乱和房间死亡。在 CSPG4 的 N 终点和 TcdB 的 C 终点之间的一个直接相互作用被证实,并且 CSPG4 的毒素绑定领域的可溶的肽能保护房间免受 TcdB 的行动的伤害。尤其是, CSPG4/NG2 的完全的损失减少了在没有显著地影响动物死亡的老鼠的被触发 TcdB 的 interleukin-8 正式就职。基于两个在里面 vitro 并且在 vivo 研究,我们为 TcdB endocytosis 建议一个双受体的模型。第一 TcdB 受体的发现为 CSPG4 揭示一个以前不受怀疑的角色并且为 C 的处理提供一个新治疗学的目标。顽固感染。 | Pengfei Yuan Hongmin Zhang Changzu Cai Shiyou Zhu Yuexin Zhou Xiaozhou Yang Ruina He Chan Li Shengjie Guo Shan Li Tuxiong Huang Gregorio Perez-Cordon Hanping Feng Wensheng Wei | 2015 | Cell Research2015，25，2： | 6 |
| 4 | 3D printing of Mg-substituted wollastonite reinforcing diopside porous bioceramics with enhanced mechanical and biological performances显示文摘Mechanical strength and its long-term stability of bioceramic scaffolds is still a problem to treat the osteonecrosis of the femoral head.Considering the long-term stability of diopside(DIO)ceramic but poor mechanical strength,we developed the DIO-based porous bioceramic composites via dilute magnesium substituted wollastonite reinforcing and three-dimensional(3D)printing.The experimental results showed that the secondary phase(i.e.10%magnesium substituting calcium silicate;CSM10)could readily improve the sintering property of the bioceramic composites(DIO/CSM10-x,x=0-30)with increasing the CSM10 content from 0%to 30%,and the presence of the CSM10 also improved the biomimetic apatite mineralization ability in the pore struts of the scaffolds.Furthermore,the flexible strength(12.5 -30 MPa)and compressive strength(14-37 MPa)of the 3D printed porous bioceramics remarkably increased with increasing CSM10 content,and the compressive strength of DIO/CSM10-30 showed a limited decay(from 37 MPa to 29 MPa)in the Tris buffer solution for a long time stage(8 weeks).These findings suggest that the new CSM10-reinforced diopside porous constructs possess excellent mechanical properties and can potentially be used to the clinic,especially for the treatment of osteonecrosis of the femoral head work as a bioceramic rod. | Dongshuang He Chen Zhuang Sanzhong Xu Xiurong Ke Xianyan Yang Lei Zhang Guojing Yang Xiaoyi Chen Xiaozhou Mou An Liu Zhongru Gou | 2016 | Bioactive Materials2016，1，1： | 5 |
| 5 | The Abnormal High Expression of B Cell Activating Factor Belonging to TNF Superfamily (BAFF) and Its Potential Role in Kidney Transplant Recipients显示文摘B cell activating factor belonging to TNF superfamily (BAFF) is a critical regulator of B cell maturation and survival. In this present study, the expression characteristic of BAFF in kidney transplantation recipients was investigated, its potential significance was analyzed and peripheral blood of follow-up kidney transplant recipients was studied. Flow cytometric assay results showed that, cell-surface BAFF was significantly highly expressed on peripheral CD3+ T lymphocytes in ≥ 5 yrs group of kidney transplant recipients, compared with other groups (p < 0.05). BAFF expression could be found on CD4+ T cells and CD8+ T cells. The BAFF mRNA levels in peripheral mononuclear cells were consistent with the protein levels. However, serum soluble BAFF levels were inter-individually different in each group. Stratified by renal function, it was found that cell-surface BAFF levels were significantly higher in those with abnormal renal function, compared with recipients with normal renal function (p < 0.05). ELISA assay results showed that expression levels of cell surface BAFF were significantly correlated with anti-HLA Ⅰ & Ⅱ antibodies. These results indicate that BAFF may be involved in the development of graft-loss and influences the long-time outcome of kidney allograft, likely mediated by interfering with immune response. | Haiyan Xu Xiaozhou He Qing Liu Yingdi Chen Yibei Zhu Dan Shi Xueguang Zhang | 2008 | Cellular & Molecular Immunology2008，5，6： | 3 |
| 6 | Abnormally High Expression of BAFF on T Lymphocytes from Lung Cancer- associated Pleural Effusions and Its Potent Anti-tumor Effect显示文摘在现在的学习,激活从恶意的肋膜的流出( MPE )在 T 淋巴细胞上属于肿瘤坏死因素家庭( BAFF )和它的受体( BAFF-R 和 TACI )的因素的 B 房间的表情被排序的激活荧光的房间( FACS )检验分析,并且与那些相比在从非恶意的肋膜的流出( NMPE )和健康控制的 T 淋巴细胞上。它被发现那 CD3 积极 T 淋巴细胞(包括 CD25 和 CD69 积极房间的 CD4 , CD8 ,和部分)在肺的 MPE ,癌症高度并且一致地表示了 BAFF 分子,当 BAFF 的高表情能仅仅在植物凝集素(公众房产管理局)或白介素被发现时,( IL-2 ) 2 从 NMPE 或健康控制导致了 T 淋巴细胞。这些结果与从由即时 PCR 的 BAFF mRNA 察觉的结果一致。另外,当 TACI 的表达式在 CD4^+ T 房间上被增加,但是减少时,从 MPE 的 T 淋巴细胞显著地从 NMPE 或健康控制比那些表示了更多的 BAFF-R,在 CD8^+ T 房间上什么时候与控制相比。Annexin/PI 试金建议 recombinant 人 BAFF (rhBAFF ) 能从 MPE 支持 T 淋巴细胞的幸存率,当圈套受体 TACI-Fc 熔化蛋白质能支持 T 淋巴细胞的 apoptosis 率时。在 ELISA 试金检测的上层清液的 Cytokines 显示出那 rhBAFF 能显著地起来在像的 TACI-Fc-treated 组在 vitro,和 IFN-gamma 水平调整 IFN-gamma 的分泌物控制组的。所有这些结果显示从 MPE 的 T 淋巴细胞上的 BAFF 的反常地高的表示可以起反肿瘤效果的一个作用。 | Haiyan XU Xiaozhou HE Yibei ZHU Tiangzan YAN Hongbin MA Xueguang ZHANG | 2007 | Acta Biochimica et Biophysica Sinica2007，39，12： | 3 |
| 7 | Frameless stereotactic aspiration and thrombolysis of moderate thalamic hemorrhage显示文摘To the editor:Frameless stereotactic aspiration and thrombolysis (FSAT) is appropriate for treating deep-seated brain hematoma such as thalamic haemorrhage (TH).1 We performed FSAT to determine the efficacy and safety of this method for treating moderate TH (hematoma volume of 10-30 ml). From December 2006 to November 2011,a total of 75 consecutive moderate TH patients were enrolled in this study.These patients were non-randomly assigned to two groups,the FSAT group and the conservative group,according to the preference of physicians or patients.The study protocol was approved by the Medical Ethics Committee of the Third Affiliated Hospital of Soochow University.The final analysis included 27 patients in the FSAT group and 48 patients in conservative group. | Lian Xuegan Huang Hongwei Wu Jian Wei Ning Zhou Jianzhong Sheng Shiying He Xiaozhou | 2014 | Chinese Medical Journal2014，，12： | 2 |
| 8 | Preconditioning with Hyperbaric Oxygen Induces Tolerance Against Renal Ischemia-Reperfusion Injury Via Increased Expression of Heme Oxygenase-1显示文摘 | Xiaozhou He Xianlin Xu Min Fan Xiao Chen Xuejun Sun Guanghua Luo Lujun Chen Qinfeng Mu Yuehua Feng Qingyan Mao Zhifu Chao | 2011 | Journal of Surgical Research2011，，2： | 2 |
| 9 | A model for universal spatial variations of temperature fluctuations inturbulent Rayleigh-Bénard convection显示文摘We propose a theoretical model for spatial variations of the temperature varianceσ2(z,r)(z is the dis-tance from the sample bottom and r the radial coordinate)in turbulent Rayleigh-Bénard convection(RBC).Adapting the“attached-eddy”modelofshearflowtothe plumesofRBC,wederivedanequationforσ2 which is based on the universal scaling of the normalized RBC temperature spectra.This equation in-cludes both logarithmic and power-law dependences on z/λth,whereλth is the thermal boundary layer thickness.The equation parameters depend on r and the Prandtl number Pr,but have only an extremelyweak dependence on the Rayleigh number Ra Thus our model provides a near-universal equation for thetemperature variance profile in turbulent RBC. | Xiaozhou He Eberhard Bodenschatz Guenter Ahlers | 2021 | Theoretical & Applied Mechanics Letters2021，11，2： | 1 |
| 10 | Capn4 contributes to tumor invasion and metastasis in clear cell renal cell carcinoma cells via modulating talin-focal adhesion kinase signaling pathway显示文摘Calpain 小子单元(Capn4 ) 1 被显示了与清楚的房间的转移 / 侵略相关肾的房间癌(ccRCC ) 。这研究试图进一步阐明位于调停 Capn4 的 ccRCC 下面的分子的机制前进。在 ccRCC 房间的 mRNA 表示层次被量的即时 PCR 测量。房间粘附,侵略,和移植上的 Capn4 的效果被房间粘附试金,房间侵略试金,和愈合创伤的试金分别地检验。蛋白质层次被西方的污点分析检测。在 vivo 的癌症转移上的 Capn4 的效果在一个裸体老鼠异种皮移植模特儿被估计。Capn4 在 ccRCC 房间是起来调整的,这被发现,并且 Capn4 overexpression 压制了房间粘附活动并且在 786-O 房间增加了房间侵略和移植,当 Capn4 silencing 增加了房间粘附活动并且损害了侵略和 Caki-1 房间的迁居能力时。Capn4 overexpression 也在 786-O 房间增加了劈开的 talin 的蛋白质水平,当 Capn4 silencing 减少了时在 Caki-1 房间的劈开的 talin 的蛋白质水平。发信号的焦点的粘附 kinase (FAK )/AKT/MAPK 被 Capn4 overexpression 在 786-O 房间激活,并且被 Capn4 下面规定在 Caki-1 房间禁止。Capn4 overexpression 增加了矩阵 metalloproteinase 的蛋白质层次 2 (MMP-2 ) ,在 786-O 房间的 vimentin, N-cadherin,和下面调整的 E-cadherin 当 Capn4 silencing 减少了时,蛋白质在 Caki-1 房间 MMP-2, vimentin, N-cadherin,和起来调整的 E-cadherin 铺平。Capn4 也支持了癌症转移在在里面 vivo 裸体人老鼠异种皮移植模型。我们的结果含有在 ccRCC 侵略和移植的 Capn4 的功能的角色,它可以在 ccRCC 贡献癌症转移。 | Qianfeng Zhuang Weiping Luo Mingran Zhang Min Fan Hao Lu Renfang Xu Xiaozhou He | 2018 | Acta Biochimica et Biophysica Sinica2018，50，5： | 1 |
| 11 | Preconditioning with hyperbaric Oxygen induces tolerance against renal ischemiareperfusion injury via increased expression of heme oxygenase- 1 显示文摘 | He Xiaozhou Xu Xianlin Fan Min | 2011 | JSurgRes2011，170，2： | 1 |
| 12 | Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo显示文摘 | Wu Yugang Wang Liang He Xiaozhou | 2008 | Cellular Immunology2008，253，2： | 1 |
| 13 | Survival after radical cystectomy for bladder cancer:Multicenter comparison between minimally invasive and open approaches显示文摘Objective:To investigate oncological outcomes in patients with bladder cancer who underwent minimally invasive radical cystectomy(MIRC)or open radical cystectomy(ORC).Methods:We identified patients with bladder cancer who underwent radical cystectomy(RC)in 13 centers of the Chinese Bladder Cancer Consortium(CBCC).Perioperative outcomes were compared between MIRC and ORC.The influence of surgical approaches on overall survival(OS)and cancer-specific survival(CSS)in the entire study group and subgroups classified according to pathologic stage or lymph node(LN)status was assessed with the log-rank test.Multivariable Cox proportional hazard models were used to evaluate the association among OS,CSS and risk factors of interest.Results:Of 2098 patients who underwent RC,1243 patients underwent MIRC(1087 laparoscopic RC and 156 robotic-assisted RC,respectively),while 855 patients underwent ORC.No significant differences were noted in positive surgical margin rate and 90-day postoperative mortality rate.MIRC was associated with less estimated blood loss,more LN yield,higher rate of neobladder diversion,longer operative time,and longer length of hospital stay.There was no significant difference in OS and CSS according to surgical approaches(pZ0.653,and 0.816,respectively).Subgroup analysis revealed that OS and CSS were not significantly different regardless of the status of extravesical involvement or LN involvement.Multivariable Cox regression analyses showed that the surgical approach was not a significant predictor of OS and CSS.Conclusions:Our study showed that MIRC was comparable to conventional ORC in terms of OS and CSS. | Weibin Xie Junming Bi Qiang Wei Ping Han Dongkui Song Lei Shi Dingwei Ye Yijun Shen Xin Gou Weiyang He Shaogang Wang Zheng Liu Jinhai Fan Kaijie Wu Zhiwen Chen Xiaozhou Zhou Chuize Kong Yang Liu Chunxiao Liu Abai Xu Baiye Jin Guanghou Fu Wei Xue Haige Chen Tiejun Pan Zhong Tu Tianxin Lin Jian Huang | 2020 | Asian Journal of Urology2020，7，3： | 1 |
| 14 | Genomic Surveillance for SARS-CoV-2—China,September 26,2022 to January 29,2023显示文摘Introduction:The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has generated 2,431 variants over the course of its global transmission over the past 3 years.To better evaluate the genomic variation of SARS-CoV-2 before and after the optimization of coronavirus disease 2019(COVID-19)prevention and control strategies,we analyzed the genetic evolution branch composition and genomic variation of SARS-CoV-2 in both domestic and imported cases in China(the data from Hong Kong and Macao Special Administrative Regions and Taiwan,China were not included)from September 26,2022 to January 29,2023.Methods:Analysis of the number of genome sequences,sampling time,dynamic changes of evolutionary branches,origin,and clinical typing of SARS-CoV-2 variants submitted by 31 provincial-level administrative divisions(PLADs)and Xinjiang Production and Construction Corps(XPCC)was conducted to assess the accuracy and timeliness of SARS-CoV-2 variant surveillance.Results:From September 26,2022 to January 29,2023,20,013 valid genome sequences of domestic cases were reported in China,with 72 evolutionary branches.Additionally,1,978 valid genome sequences of imported cases were reported,with 169 evolutionary branches.The prevalence of the Omicron variants of SARS-CoV-2 in both domestic and imported cases was consistent with that of international epidemic variants.Conclusions:This study provides an overview of the prevalence of Omicron variants of SARS-CoV-2 in China.After optimizing COVID-19 prevention and control strategies,no novel Omicron variants of SARSCoV-2 with altered biological characteristics or public health significance have been identified since December 1,2022. | Shiwen Wang Peihua Niu Qiudong Su Xiaozhou He Jing Tang Ji Wang Yenan Feng Cao Chen Xiang Zhao Zhixiao Chen Wenling Wang Zeyuan Yin Yuchao Wu Changcheng Wu Lili Li Aili Cui Yan Zhang Caiyun Long Xiaoyu Yang Zhongxian Zhang Hong Bo Wenbo Xu SARS-CoV-Genome Working Group | 2023 | China CDC weekly2023，5，7： | 1 |
| 15 | Space-time correlations in turbulent Rayleigh–Bnard convection显示文摘The recent development of the elliptic model(He,et al. Phy. Rev. E, 2006), which predicts that the space-time correlation function Cu(r, τ) in a turbulent flow has a scaling form Cu(rE, 0) with rEbeing a combined space-time separation involving spatial separation r and time delay τ, has stimulated considerable experimental efforts aimed at testing the model in various turbulent flows. In this paper, we review some recent experimental investigations of the space-time correlation function in turbulent Rayleigh–B′enard convection. The experiments conducted at different representative locations in the convection cell confirmed the predictions of the elliptic model for the velocity field and passive scalar field, such as local temperature and shadowgraph images.The understanding of the functional form of Cu(r, τ) has a wide variety of applications in the analysis of experimental and numerical data and in the study of the statistical properties of small-scale turbulence. A few examples are discussed in the review. | Xiaozhou He Penger Tong | 2014 | Acta Mechanica Sinica2014，30，4： | 1 |
| 16 | Vertical multiple-layer structure of temperature and turbulent diffusivity in the South China Sea显示文摘We report field measurements of vertical profiles of the turbulent diffusivity and temperature at different stations in the South China Sea(SCS).Our study shows that the measured turbulent diffusivity follows a power-law distribution with a varying exponent in water layers.Similar multiple-layer scaling regimes were also observed from the temperature fluctuations.Combining turbulent diffusivity and temperature fluctuations,the vertical structure of temperature was revealed.Furthermore,we discussed the temperature profiles in each layer.A constant function of a dimensionless temperature profile was found in water layers that have identical turbulence conditions.Our results reveal the multiple-layer structure of temperature in the SCS.This study contributes to the understanding of the vertical structure of multiple layers in the SCS and provides clues for exploring the physical mechanism for maintaining the temperature structure. | Xin He Changrong Liang Yang Yang Guiying Chen Xiaodong Shang Xiaozhou He Penger Tong | 2022 | Acta Oceanologica Sinica2022，41，10： | 1 |
| 17 | Cryptosporidiosis threat under climate change in China:prediction and validation of habitat suitability and outbreak risk for human-derived Cryptosporidium based on ecological niche models显示文摘Background Cryptosporidiosis is a zoonotic intestinal infectious disease caused by Cryptosporidium spp.,and its transmission is highly influenced by climate factors.In the present study,the potential spatial distribution of Cryptosporidium in China was predicted based on ecological niche models for cryptosporidiosis epidemic risk warning and prevention and control.Methods The applicability of existing Cryptosporidium presence points in ENM analysis was investigated based on data from monitoring sites in 2011–2019.Cryptosporidium occurrence data for China and neighboring countries were extracted and used to construct the ENMs,namely Maxent,Bioclim,Domain,and Garp.Models were evaluated based on Receiver Operating Characteristic curve,Kappa,and True Skill Statistic coefficients.The best model was constructed using Cryptosporidium data and climate variables during 1986‒2010,and used to analyze the effects of climate factors on Cryptosporidium distribution.The climate variables for the period 2011‒2100 were projected to the simulation results to predict the ecological adaptability and potential distribution of Cryptosporidium in future in China.Results The Maxent model(AUC=0.95,maximum Kappa=0.91,maximum TSS=1.00)fit better than the other three models and was thus considered the best ENM for predicting Cryptosporidium habitat suitability.The major suitable habitats for human-derived Cryptosporidium in China were located in some high-population density areas,especially in the middle and lower reaches of the Yangtze River,the lower reaches of the Yellow River,and the Huai and the Pearl River Basins(cloglog value of habitat suitability>0.9).Under future climate change,non-suitable habitats for Cryptosporidium will shrink,while highly suitable habitats will expand significantly(χ^(2)=76.641,P<0.01;χ^(2)=86.836,P<0.01),and the main changes will likely be concentrated in the northeastern,southwestern,and northwestern regions.Conclusions The Maxent model is applicable in prediction of Cryptosporidium habitat suitability and can achieve excellent simulation results.These results suggest a current high risk of transmission and significant pressure for cryptosporidiosis prevention and control in China.Against a future climate change background,Cryptosporidium may gain more suitable habitats within China.Constructing a national surveillance network could facilitate further elucidation of the epidemiological trends and transmission patterns of cryptosporidiosis,and mitigate the associated epidemic and outbreak risks. | Xu Wang Yanyan Jiang Weiping Wu Xiaozhou He Zhenghuan Wang Yayi Guan Ning Xu Qilu Chen Yujuan Shen Jianping Cao | 2023 | Infectious Diseases of Poverty2023，12，2： | 0 |
| 18 | Elevated expression of hepcidin post-renal ischemia reperfusion injury显示文摘 | Cuixing Zhou Xiaozhou He Dong Xue Nin Xu | 2013 | Acta Biochimica et Biophysica Sinica2013，45，4： | 0 |
| 19 | Back to Science in Searching for SARS-CoV-2 Origins显示文摘In recent decades,emerging and re-emerging human-infecting pathogens have been represented as huge threats to public health and have become a global concern(1).After outbreaks of two coronaviruses(CoVs),severe acute respiratory syndrome coronavirus(SARS-CoV)and Middle East respiratory syndrome coronavirus(MERS-CoV),severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)became the first-known pandemic hastening CoV with tremendous wrecking to the world(2).The origin tracing of these emerging pathogens is of great significance in infectious disease prevention and control(3–4).The origin of SARS-CoV-2 remains elusive after the more than 3-year pandemic,though scientists around the world are making great efforts.From the experience of studying many other infectious pathogens,origin tracing is systematic and time-consuming work.The supposed origins of many infectious pathogens are still in debate,including SARS-CoV and human immunodeficiency virus,etc(5). | William J Liu Wenwen Lei Xiaozhou He Peipei Liu Qihui Wang Zhiqiang Wu Yun Tan Shuhui Song Gary Wong Jian Lu Jingkun Jiang Qiang Wei Mingkun Li Juncai Ma Xiaozhong Peng Yixue Li Baoxu Huang Yigang Tong Jun Han Guizhen Wu | 2023 | China CDC weekly2023，5，14： | 0 |
| 20 | A Knowledge Survey on Health Education of Echinococcosis Among Students — Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China, 2020显示文摘Summary What is already known about this topic?Previous surveys have mainly focused on how well residents and primary school students have understood the core knowledge of echinococcosis control and are limited in terms of the comprehensiveness of the knowledge category and respondents.What is added by this report?There were some shortcomings in related knowledge of echinococcosis among students,which showed a tendency to know methods but not the rationale.The differences among regions indicated a lack of a unified system for training educators and allocating comprehensive educational material.What are the implications for public health practices?The results of this study provide evidence to potentially help improve health education programs in the new phase of echinococcosis prevention and control in China. | Xu Wang Meihua Fu Qian Wang Wei Li Zeli Danba Shuai Han Xiaozhou He Jianfeng Ba Chumu Luorong Quzhen Jiangyang Yixi Luorong Dali Chunyang Li Dandan Shi Yayi Guan Weiping Wu Ning Xiao | 2022 | China CDC weekly2022，4，8： | 0 |
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