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| 1 | Meso-Cenozoic Evolution of Earth Surface System under the East Asian Tectonic Superconvergence显示文摘The East Asian geological setting has a long duration related to the superconvergence of the Paleo-Asian, Tethyan and Paleo-Pacific tectonic domains. The Triassic Indosinian Movement contributed to an unified passive continental margin in East Asia. The later ophiolites and I-type granites associated with subduction of the Paleo-Pacific Plate in the Late Triassic, suggest a transition from passive to active continental margins. With the presence of the ongoing westward migration of the Paleo-Pacific Subduction Zone, the sinistral transpressional stress field could play an important role in the intraplate deformation in East Asia during the Late Triassic to Middle Jurassic, being characterized by the transition from the E-W-trending structural system controlled by the Tethys and Paleo-Asian oceans to the NE-trending structural system caused by the Paleo-Pacific Ocean subduction. The continuously westward migration of the subduction zones resulted in the transpressional stress field in East Asia marked by the emergence of the Eastern North China Plateau and the formation of the Andean-type active continental margin from late Late Jurassic to Early Cretaceous(160-135 Ma), accompanied by the development of a small amount of adakites. In the Late Cretaceous(135-90 Ma), due to the eastward retreat of the Paleo-Pacific Subduction Zone, the regional stress field was replaced from sinistral transpression to transtension. Since a large amount of late-stage adakites and metamorphic core complexes developed, the Andean-type active continental margin was destroyed and the Eastern North China Plateau started to collapse. In the Late Cretaceous, the extension in East Asia gradually decreased the eastward retreat of the Paleo-Pacific subduction zones. Futhermore, a significant topographic inversion had taken place during the Cenozoic that resulted from a rapid uplift of the Tibet Plateau resulting from the India-Eurasian collision and the formation of the Bohai Bay Basin and other basins in the East Asian continental margin. The inversion caused a remarkable eastward migration of deformation, basin formation and magmatism. Meanwhile, the basins that mainly developed in the Paleogene resulted in a three-step topography which typically appears to drop eastward in altitude. In the Neogene, the basins underwent a rapid subsidence in some depressions after basin-controlled faulting, as well as the intracontinental extensional events in East Asia, and are likely to be a contribution to the uplift of the Tibetan Plateau. | DMITRIENKO Liudmila V. WANG Pengcheng LI Sanzhong CAO Xianzhi Ian SOMERVILLE ZHOU Zaizheng HU Mengying SUO Yanhui GUO Lingli WANG Yongming LI Xiyao LIU Xin YU Shengyao ZHU Junjiang | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 6 |
| 2 | SbMYB3 transcription factor promotes root-specific f lavone biosynthesis in Scutellaria baicalensis显示文摘Scutellaria baicalensis Georgi produces abundant root-specific f lavones(RSFs),which provide various benefits to human health.We have elucidated the complete biosynthetic pathways of baicalein and wogonin.However,the transcriptional regulation of f lavone biosynthesis in S.baicalensis remains unclear.We show that the SbMYB3 transcription factor functions as a transcriptional activator involved in the biosynthesis of RSFs in S.baicalensis.Yeast one-hybrid and transcriptional activation assays showed that SbMYB3 binds to the promoter of flavone synthase II-2(SbFNSII-2)and enhances its transcription.In S.baicalensis hairy roots,RNAi of SbMYB3 reduced the accumulation of baicalin and wogonoside,and SbMYB3 knockout decreased the biosynthesis of baicalein,baicalin,wogonin,and wogonoside,whereas SbMYB3 overexpression enhanced the contents of baicalein,baicalin,wogonin,and wogonoside.Transcript profiling by qRT–PCR demonstrated that SbMYB3 activates SbFNSII-2 expression directly,thus leading to more abundant accumulation of RSFs.This study provides a potential target for metabolic engineering of RSFs. | Yumin Fang Jie Liu Minmin Zheng Sanming Zhu Tianlin Pei Mengying Cui Lijing Chang Hanwen Xiao Jun Yang Cathie Martin Qing Zhao | 2023 | Horticulture Research2023，10，2： | 2 |
| 3 | Overexpression of Sirt6 ameliorates sleep deprivation induced-cognitive impairment by modulating glutamatergic neuron function显示文摘Sleep benefits the restoration of energy metabolism and thereby suppo rts neuronal plasticity and cognitive behaviors.Sirt6 is a NAD+-dependent protein deacetylase that has been recognized as an essential regulator of energy metabolism because it modulates various transcriptional regulators and metabolic enzymes.The aim of this study was to investigate the influence of Sirt6 on cerebral function after chronic sleep deprivation(CSD).We assigned C57BL/6J mice to control or two CSD groups and subjected them to AAV2/9-CMV-EGFP or AAV2/9-CMV-Sirt6-EGFP infection in the prelimbic cortex(PrL).We then assessed cerebral functional connectivity(FC) using resting-state functional MRI,neuron/astrocyte metabolism using a metabolic kinetics analysis;dendritic spine densities using sparse-labeling;and miniature excitato ry postsynaptic currents(mEPSCs) and action potential(AP) firing rates using whole-cell patchclamp recordings.In addition,we evaluated cognition via a comprehensive set of behavioral tests.Compared with controls,Sirt6 was significantly decreased(P<0.05) in the PrL after CSD,accompanied by cognitive deficits and decreased FC between the PrL and accumbens nucleus,piriform cortex,motor co rtex,somatosensory co rtex,olfactory tubercle,insular cortex,and cerebellum.Sirt6 ove rexpression reve rsed CSD-induced cognitive impairment and reduced FC.Our analysis of metabolic kinetics using [1-13C] glucose and [2-13C] acetate showed that CSD reduced neuronal Glu4and GABA2synthesis,which could be fully restored via forced Sirt6 expression.Furthermore,Sirt6 ove rexpression reversed CSD-induced decreases in AP firing rates as well as the frequency and amplitude of mEPSCs in PrL pyramidal neurons.These data indicate that Sirt6 can improve cognitive impairment after CSD by regulating the PrL-associated FC network,neuronal glucose metabolism,and glutamatergic neurotransmission.Thus,Sirt6 activation may have potential as a novel strategy for treating sleep disorder-related diseases. | Jinpiao Zhu Chang Chen Zhen Li Xiaodong Liu Jingang He Ziyue Zhao Mengying He Binbin Nie Zili Liu Yingying Chen Kuanpin Su Xiang Li Juxiang Chen Hongbing Xiang Fuqiang Xu Kangguang Lin Zongze Zhang Jie Wang | 2023 | Neural Regeneration Research2023，18，11： | 1 |
| 4 | A New Approach for Estimating the Number of Sources under the Coexis- tence of Circular and Various Noncircular Sources 显示文摘 | Si Weijian Zhu Tong Zhang Mengying | 2013 | Circuits Systems and Signal Processing2013，32，6： | 1 |
| 5 | Carrier frequency disturbance distributions on GPS during equatorial ionospheric scintillation显示文摘In the equatorial region,deep amplitude fading in global positioning system(GPS)signals frequently occurs during the strong ionospheric scintillation,it can lead to the loss of lock in GPS carrier tracking loops,and result in increased positioning error and even navigation interruption.The relationships between amplitude scintillation indices and detrended carrier frequency are investigated,based on GPS L1 C/A signals during the last peak of the solar cycle at the low latitude site of São Josédos Campos,Brazil(23.2S,45.9W)from 2013 to 2015.Corresponding mathematic model of the probability distribution function is built for the first time to provide statistical analysis on the above relationships.The results show that the standard carrier frequencies reveal an almost linear relation with the amplitude scintillation indices.Moreover,the frequency widths of detrended frequency are proportional to levels of amplitude scintillation when the value of the peak probability is lower than the corresponding boundary.A conclusion can be drawn that different levels of amplitude scintillation will influence the fluctuation of the carrier frequency.The analysis will provide useful guidance to set the receiver’s bandwidth with respect to the different scintillation levels and design the advanced tracking algorithms to improve the robustness and precision of the GPS receiver. | ZHU Xuefen LIN Mengying CHEN Xin CHEN Xiyuan | 2020 | Journal of Systems Engineering and Electronics2020，31，6： | 1 |
| 6 | Overexpression of the mTERT gene by adenoviral vectors promotes the proliferation of neuronal stem cells in vitro and stimulates neurogenesis in the hippocampus of mice显示文摘We sought to construct the adenoviral vector carrying the gene encoding mouse telomerase reverse transcriptase(mTERT),as well as detect its expression and effect on the proliferation of neuronal stem cells.mTERT was am-plified by RT-PCR and then the eukaryotic expression vector of pDC-EGFP-TERT was constructed.After DNA sequence analysis,we detected that there were 293 cells transfected with pDC-EGFP-TERT and helper adenovirus plasmid pBHG lox ΔE1,and three Cre using Lipofectamine 2000 mediation,named Ad-mTERT-GFP,to pack-age adenoviral particles.The Ad-mTERT-GFP was used to infect neuronal stem cells and then the expression and activity of mTERT were detected.In addition,Bromodeoxyuridine labeling test identified the impact of mTERT overexpression on proliferation of neuronal stem cells.The recombinant adenoviral vector confirmed that mTERT was successfully constructed.Overexpression of mTERT stimulated the proliferation of neuronal stem cells both in vitro and in vivo.mTERT overexpression via adenoviral vector carrying mTERT cDNA upregulated the ability of proliferation in neuronal stem cells. | Mengying Liu Yao Hu Lijuan Zhu Chen Chen Yu Zhang Weixiang Sun Qigang Zhou | 2012 | The Journal of Biomedical Research2012，26，5： | 1 |
| 7 | iRGD-reinforced, photo-transformable nanoclusters toward cooperative enhancement of intratumoral penetration and antitumor efficacy显示文摘Insufficient intratumoral penetration greatly hurdles the anticancer performance of nanomedicine. To realize highly efficient tumor penetration in a precisely and spatiotemporally controlled manner, far-red light-responsive nanoclusters (NCs) capable of size shrinkage and charge conversion were developed and co-administered with iRGD to synergistically improve the intratumoral penetration and the anticancer efficacy. The NCs were constructed using the singlet oxygen-sensitive (SOS) polyethylene glycolpolyurethane-polyethylene glycol (PEG-(1O2)PU-PEG) triblock copolymer to encapsulate the doxorubicin (DOX)-loaded, chlorin e6 (Ce6)-conjugated polyamindoamine (PAMAM) dendrimer (DCD) via the double-emulsion method. Co-administration of iRGD notably increased the permeability of NCs within tumor vasculature and tumor tissues. In addition, upon far-red light irradiation (660 nm) of tumors at low optical density (10 mW/cm2), the generated 1O2 could disintegrate the NCs and release the DCD with positive surface charge and ultra-small size (~ 5 nm), which synergized with iRGD to enable deep intratumoral penetration. Consequently, the local 1O2 at lethal concentrations along with the released DOX efficiently and cooperatively eradicated tumor cells. This study provides a convenient approach to spatiotemporally promote the intratumoral penetration of nanomedicine and mediate programmed anticancer therapy. | Jing Yan Rongying Zhu Fan Wu Ziyin Zhao Huan Ye Mengying Hou Yong Liu Lichen Yin | 2020 | Nano Research2020，13，10： | 1 |
| 8 | Degradation kinetic study of lysine in lysine hydrochloride solutions for injection by determining its main degradation product显示文摘A limited number of researches have been reported to apply the Arrhenius equation to study the relationship between drugs and its degradation products so far.In the present work,the thermal degradation kinetics of lysine hydrochloride solutions for injection,the special solvent for ademetionine 1,4-butanedisulfonate(SAM)for injection,was investigated at selected temperatures and pH values.The main degradation product of lysine was separated,purified,and confirmed as lysine lactam.A reversed-phase high performance liquid chromatographic(RP-HPLC)method without derivation was developed for the simultaneous determination of lysine and lysine lactam.The results confirmed that both the lysine degradation and lysine lactam generation followed zero-order reaction kinetics.The degradation and generation rate constants increased with increasing temperatures and decreasing pH values.The temperature-dependent degradation and generation reaction could be sufficiently modeled on the Arrhenius equation with the activation energy of 80.14 and 83.22 kJ/mol,respectively.Meanwhile,a linear relationship existed between the amount of lysine degradation and lysine lactam generation since the approximate activation energy.Considering there could be other side effects,we established an upper limit of lysine lactam(500 mg/ml),as the acceptable criteria for stability to estimate the shelf life together with lysine,which made the prediction more accurate and credible.Extrapolation data demonstrated that the lysine hydrochloride solutions for injection could be stable for two years stored at room temperature. | Mengying Tao Meng Zhu Chunnuan Wu Zhonggui He | 2015 | Asian Journal of Pharmaceutical Sciences2015，10，1： | 1 |
| 9 | Developments in diagnostic applications of saliva in human organ diseases显示文摘Saliva is one of the important body fluids that reflects normal internal characteristics and disease state of an individual.As a multi-composition oral fluid,has high potential for the surveillance of general health and disease,which contains various disease signal biomarkers and is non-invasive,convenient,fast and easy to be accepted by patients.At present,saliva is increasingly used as a biological fluid for diagnosis,monitoring systemic disease states and predicting disease progression,which has been verified.In this review,the molecular compositions and effectiveness of saliva as reliable biological fluid were discussed.Besides the latest research progress in the diagnosis of saliva related to 14 organs were reviewed.The factors affecting saliva diagnosis were discussed.The method to improve the accuracy of prediction through artificial intelligence combined with microfluidic chip was proposed,which laid the foundation for dealing with the prevention,diagnosis,and treatment of related diseases through saliva with great and long-term significance. | Yangyang Cui Mengying Yang Jia Zhu Hangkun Zhang Zhili Duan Song Wang Zhenhua Liao Weiqiang Liu | 2022 | Medicine in Novel Technology and Devices2022，，1： | 0 |
| 10 | Impact of the national hepatitis B immunization program in China:a modeling study显示文摘Background:Elimination of hepatitis B virus(HBV)is a striking challenge for countries with high or moderate disease burden.Therefore,using China as a practical case to share experiences for similar countries may accelerate the achievement of the WHO 2030 target of 90%reduction in HBV-related incidence.We aim to evaluate the impact of national HBV immunization strategies in China;and the feasibility to achieve WHO 2030 targets under diferent scenarios.Methods:We constructed an expanded Susceptible-Exposed-Infectious-Recovered(SEIR)model and decision treeMarkov model to estimate the epidemic of HBV in China,assess the feasibility of 2030 Elimination Goals through the projections and conduct the economic analysis.Least square method was used to calibrate the expanded SEIR model by yearly data of laboratory-confrmed HBV cases from 1990 to 2018.Two models were separately used to evaluate the impact and cost-efectiveness of HBV vaccine by comparing prevalence of chronic HBV infections,qualityadjusted life-years(QALYs),incremental cost efectiveness ratio and beneft–cost ratio(BCR)under various intervention options,providing a basis for exploring new containment strategies.Results:Between 1990 and 2020,the number of chronic HBV infections decreased by 33.9%.The current status quo would lead to 55.73 million infections(3.95%prevalence)in 2030,compared to 90.63 million(6.42%prevalence)of the“Without the NIP”scenario(NIP:National Immunization Program),114.78 million(8.13%prevalence)without any interventions.The prevention of mother to child transmission(PMTCT)strategy showed a net beneft as 12,283.50 dollars per person,with BCR as 12.66,which is higher than that of universal vaccination at 9.49.Compared with no screening and no vaccination,the PMTCT strategy could save 7726.03 dollars for each QALY increase.Conclusions:Our fndings proved the HBV vaccination has demonstrated a substantial positive impact on controlling the epidemic of HBV in terms of efectiveness and economy after about 30 years of implementation of the national hepatitis B immunization program which also provided containment experience for high or medium burden countries.As for China,the next step should focus on exploring strategies to improve diagnosis and treatment coverage to reduce the burden of HBV-related deaths and ultimately eliminate HBV. | Zhixi Liu Mengying Li David W.Hutton Abram L.Wagner Ye Yao Wenlong Zhu Lingsheng Cao Shenglan Tang Jinhua Pan Yesheng Wang Qi Zhao Hong Ren Ying Wang Weibing Wang | 2022 | Infectious Diseases of Poverty2022，11，5： | 0 |
| 11 | Forkhead box family transcription factors as versatile regulators for cellular reprogramming to pluripotency显示文摘Forkhead box(Fox)transcription factors play important roles in mammalian development and disease.However,their function in mouse somatic cell reprogramming remains unclear.Here,we report that FoxD subfamily and FoxG1 accelerate induced pluripotent stem cells(iPSCs)generation from mouse fibroblasts as early as day4 while FoxA and FoxO subfamily impede this process obviously.More importantly,FoxD3,FoxD4 and FoxG1 can replace Oct4 respectively and generate iPSCs with germline transmission together with Sox2 and Klf4.On the contrary,FoxO6 almost totally blocks reprogramming through inhibiting cell proliferation,suppressing the expression of pluripotent genes and hindering the process of mesenchymal to epithelial transition(MET).Thus,our study uncovers unexpected roles of Fox transcription factors in reprogramming and offers new insights into cell fate transition. | Meijun Fu Huan Chen Zepo Cai Yihang Yang Ziyu Feng Mengying Zeng Lijun Chen Yue Qin Baomei Cai Pinghui Zhu Chunhua Zhou Shengyong Yu Jing Guo Jing Liu Shangtao Cao Duanqing Pei | 2021 | Cell Regeneration2021，10，1： | 0 |
| 12 | Detection and Analysis of Strong Ionospheric Scintillation in Equatorial Region显示文摘To detect the occurrence of ionospheric scintillation in the equatorial region,a coherent/non-coherent integration method is adopted on the accumulation of intermediate frequency(IF)signal and local code,in the process of signal acquisition based on software receiver.The processes of polynomial fitting and sixth-order Butterworth filtering are introduced to detrend the tracking results.Combining with ionospheric scintillation detection algorithm and preset thresholds,signal acquisition and tracking,scintillation detection,positioning solution are realized under the influence of strong ionospheric scintillation.Under the condition that the preset threshold of amplitude and carrier phase scintillation indices are set to 0.5 and 0.15,and the percentage of scin-tillation occurrence is 50%,respectively,PRN 12 and 31 affected by strong amplitude scintillation are detected effectively.Results show that the positioning errors in the horizontal direction are below 5m approximately.The software receiver holds performances of accurate acquisition,tracking and positioning on the strong ionospheric scintillation conditions,which can provide important basis and helpful guidance for relevant research on ionospheric scintillation,space weather and receiver design with high performance. | ZHU Xuefen LIN Mengying LU Zhengpeng CHEN Xiyuan | 2021 | Instrumentation2021，8，4： | 0 |
| 13 | Gap-free genome assembly and CYP450 gene family analysis reveal the biosynthesis of anthocyanins in Scutellaria baicalensis显示文摘Scutellaria baicalensis Georgi,a member of the Lamiaceae family,is a widely utilized medicinal plant.The flavones extracted from S.baicalensis contribute to numerous health benefits,including anti-inflammatory,antiviral,and anti-tumor activities.However,the incomplete genome assembly hinders biological studies on S.baicalensis.This study presents the first telomere-to-telomere(T2T)gap-free genome assembly of S.baicalensis through the integration of Pacbio HiFi,Nanopore ultra-long and Hi-C technologies.A total of 384.59 Mb of genome size with a contig N50 of 42.44 Mb was obtained,and all sequences were anchored into nine pseudochromosomes without any gap or mismatch.In addition,we analysed the major cyanidin-and delphinidin-based anthocyanins involved in the determination of blue-purple flower using a widely-targeted metabolome approach.Based on the genome-wide identification of Cytochrome P450(CYP450)gene family,three genes(SbFBH1,2,and 5)encoding flavonoid 3′-hydroxylases(F3′Hs)and one gene(SbFBH7)encoding flavonoid 3′5′-hydroxylase(F3′5′H)were found to hydroxylate the B-ring of flavonoids.Our studies enrich the genomic information available for the Lamiaceae family and provide a toolkit for discovering CYP450 genes involved in the flavonoid decoration. | Tianlin Pei Sanming Zhu Weizhi Liao Yumin Fang Jie Liu Yu Kong Mengxiao Yan Mengying Cui Qing Zhao | 2023 | Horticulture Research2023，10，12： | 0 |
| 14 | Immune characteristics of severe and critical COVID-19 patients显示文摘Dear Editor,Recently,the novel coronavirus disease(COVID-19)has broken out worldwide,1 with rapid increase of infected patients.COVID-19 dominantly leads to pneumonia.2 Among these COVID-19 patients,some appears to be severe symptoms with acute respiratory distress syndrome,organ failure,2 and further present a poor outcome. | Li Yang Jianjun Gou Jianbo Gao Lan Huang Zhiqiang Zhu Shaofei Ji Hongchun Liu Lihua Xing Mengying Yao Yi Zhang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 15 | Hif1蛋白结合组蛋白H2A-H2B二聚体和H3-H4四聚体的结构生物学研究显示文摘组蛋白分子伴侣通过严格调控组蛋白的翻译后修饰,确保了核小体组装及解聚过程中组蛋白的正确沉积及解离,进而调节染色质结构并改变基因活性。 | Mengying Zhang 刘合军 Yongxiang Gao Zhongliang Zhu Zijun Chen Peiyi Zheng Lu Xue Jixi Li 滕脉坤 牛立文 | 2017 | 科学新闻2017，19，4： | 0 |
| 16 | Enhancing Network Throughput via the Equal Interval Frame Aggregation Scheme for IEEE 802.11ax WLANs显示文摘Frame aggregation is fully supported in the newly published IEEE 802.11ax standard to improve throughput.With frame aggregation,a mobile station combines multiple subframes into an aggregate MAC service data unit(A-MSDU)or an aggregate MAC protocol data unit(A-MPDU)for transmission.It is challenging for a mobile station in 802.11ax WLANs to set an appropriate number of subframes being included in an AMSDU or A-MPDU.This problem is solved in this paper by the proposed equal interval frame aggregation(EIFA)scheme which lets a mobile station aggregate at most k subframes at a fixed time period of T.A novel Markov model is developed for deriving the probability of number of subframes in the data buffer at the mobile station,resulting in the throughput and packet delay in the EIFA.Moreover,the optimization problem of maximizing the throughput with the constraint on delay is formulated,and its solution leads to the optimal pair of parameters k and T for improving throughput in the EIFA scheme.Simulation results show the EIFA has a higher throughput than the ones in which the mobile station chooses the minimum,the maximum,or a random number of subframes. | ZHU Yihua XU Mengying | 2023 | Chinese Journal of Electronics2023，32，4： | 0 |
| 17 | Development of Improved Mumps Vaccine Candidates by Mutating Viral mRNA Cap Methyltransferase Sites in the Large Polymerase Protein显示文摘Although a live attenuated vaccine is available for controlling mumps virus(MuV), mumps still outbreaks frequently worldwide. The attenuated MuV vaccine strain S79 is widely used in mumps vaccination in China, but still with many shortcomings, among which the most prominent are the side effects and decreased immunity. Therefore, there is a need to further improve the safety and efficacy of the current MuV vaccine. In the present study, we further attenuated MuV S79 vaccine strain by inhibiting viral mRNA methyltransferase(MTase). We generated a panel of eight recombinant MuVs(rMuVs) carrying mutations in the MTase catalytic site or S-adenosylmethionine(SAM) binding site in the large(L) polymerase protein. These rMuVs are genetically stable and seven rMuVs are more attenuated in replication in cell culture and five r MuVs are more attenuated in replication in lungs of cotton rats compared with the parental vaccine strain S79. Importantly, cotton rats vaccinated with these seven rMuV mutants produced high levels of serum neutralizing antibodies and were completely protected against challenge with a wild-type MuV strain(genotype F). Therefore, our results demonstrate that alteration in the MTase catalytic site or SAM binding site in MuV L protein improves the safety or the immunogenicity of the MuV vaccine and thus mRNA cap MTase may be an effective target for the development of new vaccine candidates for MuV. | Xiaoqiang Hao Yilong Wang Mengying Zhu Dongming Zhou Rongxian Liu Bin Wang Yao-Wei Huang Zhengyan Zhao | 2021 | Virologica Sinica2021，36，3： | 0 |
| 18 | Double-bowl state in photonic Dirac nodal line semimetal显示文摘The past decade has seen a proliferation of topological materials for both insulators and semimetals in electronic systems and classical waves.Topological semimetals exhibit topologically protected band degeneracies,such as nodal points and nodal lines.Dirac nodal line semimetals(DNLS),which own four-fold line degeneracy,have drawn particular attention.DNLSs have been studied in electronic systems but there is no photonic DNLS.Here in this work,we provide a new mechanism,which is unique for photonic systems to investigate a stringent photonic DNLS.When truncated,the photonic DNLS exhibits double-bowl states(DBS),which comprise two sets of perpendicularly polarized surface states.In sharp contrast to nondegenerate surface states in other photonic systems,here the two sets of surface states are almost degenerate over the whole-spectrum range.The DBS and the bulk Dirac nodal ring(DNR)dispersion along the relevant directions,are experimentally resolved. | Mengying Hu Ye Zhang Xi Jiang Tong Qiao Qiang Wang Shining Zhu Meng Xiao Hui Liu | 2021 | Light(Science & Applications)2021，10，9： | 0 |
| 19 | Activity-Dependent Phosphorylation of CDKL5 at Serine 407 Regulates Synaptogenesis and Plasticity显示文摘Dear Editor,The X-linked gene cyclin-dependent kinase-like 5(CDKL5)encodes a serine/threonine kinase that is associated with CDKL5-deficiency disorder(CDD),a severe developmental and epileptic encephalopathy characterized by early-onset seizures,gross developmental delay,and motor disabilities[1].The expression of CDKL5 is highly enriched in the brain and is significantly induced during postnatal development[2]. | Mengying Jiang Qiwu Xu Can Yang Dan Li Ji-Wei Liu Yuxian Zhang Yong-Chuan Zhu Zhi-Qi Xiong | 2023 | Neuroscience Bulletin2023，39，9： | 0 |
| 20 | Eco-friendly iron-catalyzed oxidation of unstrained tertiary aromatic alcohols to ketones显示文摘A general,facile and eco-friendly iron catalysis enables oxidation of unstrained tertiary aromatic alcohols to ketones through C-C bond cleavage even with H_(2)O_(2) as the oxidant.Notably,this transformation can tolerate oxidation-labile functional groups.The robustness of this method is further demonstrated on the late-stage oxidation of complex bioactive molecules. | Shanmei Zhu Penghui Hu Mengying Guo Linlin Zhao Linlin Yang Wei-Jin Gu Wei Han | 2024 | Chinese Chemical Letters2024，35，1： | 0 |
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