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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Computed tomography and magnetic resonance imaging evaluation of pelvic lymph node metastasis in bladder cancer显示文摘Background:Accurate evaluation of lymph node metastasis in bladder cancer(BCa)is important for disease staging,treatment selection,and prognosis prediction.In this study,we aimed to evaluate the diagnostic accuracy of com-puted tomography(CT)and magnetic resonance imaging(MRI)for metastatic lymph nodes in BCa and establish criteria of imaging diagnosis.Methods:We retrospectively assessed the imaging characteristics of 191 BCa patients who underwent radical cys-tectomy.The data regarding size,shape,density,and diffusion of the lymph nodes on CT and/or MRI were obtained and analyzed using Kruskal-Wallis test and χ^(2) test.The optimal cutoff value for the size of metastatic node was deter-mined using the receiver operating characteristic(ROC)curve analysis.Results:A total of 184 out of 3317 resected lymph nodes were diagnosed as metastatic lymph nodes.Among 82 imaging-detectable lymph nodes,51 were confirmed to be positive for metastasis.The detection rate of metastatic nodes increased along with more advanced tumor stage(P<0.001).Once the ratio of short-to long-axis diameter≤0.4 or fatty hilum was observed in lymph nodes on imaging,it indicated non-metastases.Besides,lymph nodes with spiculate or obscure margin or necrosis indicated metastases.Furthermore,the short diameter of 6.8 mm was the optimal threshold to diagnose metastatic lymph node,with the area under ROC curve of 0.815.Conclusions:The probability of metastatic nodes significantly increased with more advanced T stages.Once lymph nodes are detected on imaging,the characteristic signs should be paid attention to.The short diameter>6.8 mm may indicate metastatic lymph nodes in BCa. | Yong Li Feiyu Diao Siya Shi Kaiwen Li Wangshu Zhu Shaoxu Wu Tianxin Lin | 2018 | Cancer Communications2018，38，1： | 7 |
| 3 | Quasi-phase-matching-division multiplexing holography in a three-dimensional nonlinear photonic crystal显示文摘Nonlinear holography has recently emerged as a novel tool to reconstruct the encoded information at a new wavelength,which has important applications in optical display and optical encryption.However,this scheme still struggles with low conversion efficiency and ineffective multiplexing.In this work,we demonstrate a quasi-phasematching(QPM)-division multiplexing holography in a three-dimensional(3D)nonlinear photonic crystal(NPC).3D NPC works as a nonlinear hologram,in which multiple images are distributed into different Ewald spheres in reciprocal space.The reciprocal vectors locating in a given Ewald sphere are capable of fulfilling the complete QPM conditions for the high-efficiency reconstruction of the target image at the second-harmonic(SH)wave.One can easily switch the reconstructed SH images by changing the QPM condition.The multiplexing capacity is scalable with the period number of 3D NPC.Our work provides a promising strategy to achieve highly efficient nonlinear multiplexing holography for high-security and high-density storage of optical information. | Pengcheng Chen Chaowei Wang Dunzhao Wei Yanlei Hu Xiaoyi Xu Jiawen Li Dong Wu Jianan Ma Shengyun Ji Leran Zhang Liqun Xu Tianxin Wang Chuan Xu Jiaru Chu Shining Zhu Min Xiao Yong Zhang | 2021 | Light(Science & Applications)2021，10，8： | 5 |
| 4 | Periodically poled LiNbO3 crystals from 1D and 2D to 3D显示文摘A periodically-poled LiNbO3(PPLN) crystal features space-dependent second-order nonlinear coefficients, which is one of the most important materials to effectively control nonlinear optical interactions through quasi-phase matching(QPM). By using electric-field poling method, 1D and 2D PPLN crystals have been successfully fabricated for laser frequency conversion, quantum light sources, nonlinear beam shaping and nonlinear optical imaging. Recently, femtosecond laser engineering technique is utilized to prepare 3D domain structures inside LiNbO3 crystal, which provides a promising platform to control nonlinear interacting waves in 3D configuration. After 40 years of developments, PPLN crystals still have exciting prospects in fundamental researches and practical applications for integrated photonic chip, quantum information processing,and so on. | WANG TianXin CHEN PengCheng XU Chuan ZHANG Yong WEI DunZhao HU XiaoPeng ZHAO Gang XIAO Min ZHU ShiNing | 2020 | Science China(Technological Sciences)2020，63，7： | 3 |
| 5 | Performance Evaluation Method for Automated Driving System in Logical Scenario显示文摘With the continuous improvement of automated driving technology,how to evaluate the performance of an automated driving system is attracting more and more attention.Meanwhile,with the creation of scenario-based test methods,the traditional evaluation index based on a single test can no longer meet the requirements of high-level safety verification for automated driving system,and the performance evaluation of such a system in logical scenarios will be the mainstream.Based on the scenario-based test method and Turing test theory,a performance evaluation method for an automated driving system in the whole parameter space of a logical scenario is proposed.The logical scenario parameter space is partitioned according to the risk degree of concrete scenario,and the evaluation process in different zones are determined.Subsequently,the anthropo-morphic index in the safe zone and the collision-avoidance index in the danger zone are defined by comparing test results of human driving and ideal vehicle motion.Taking front vehicle low-speed and cut-out scenarios as examples,two automated driving algorithms are tested in the virtual environment,and the test results are evaluated both by the proposed method and by human observation.The results show that the results of the proposed method are consistent with the subjective feelings of humans;additionally,it can be applied to scenario-based tests and the verification process of an automated driving system. | Peixing Zhang Bing Zhu Jian Zhao Tianxin Fan Yuhang Sun | 2022 | Automotive Innovation2022，5，3： | 1 |
| 6 | The downregulation of ErbB3 binding protein 1 (EBP1) is associated with poor prognosis and enhanced cell proliferation in hepatocellular carcinoma显示文摘 | Baoying Hu Yicheng Xiong Runzhou Ni Lixian Wei Dawei Jiang Gang Wang Di Wu Tianxin Xu Fengbo Zhao Mingyan Zhu Chunhua Wan | 2014 | 2014 (1-2)2014，，1： | 1 |
| 7 | Multi-source data-based 3D digital preservation of large scale ancient chinese architecture:A case report显示文摘The 3D digitalization and documentation of ancient Chinese architecture is challenging because of architectural complexity and structural delicacy.To generate complete and detailed models of this architecture,it is better to acquire,process,and fuse multi-source data instead of single-source data.In this paper,we describe our work on 3D digital preservation of ancient Chinese architecture based on multi source data.We first briefly introduce two surveyed ancient Chinese temples,Foguang Temple and Nanchan Temple.Then,we report the data acquisition equipment we used and the multi-source data we acquired.Finally,we provide an overview of several applications we conducted based on the acquired data,including ground and aerial image fusion,image and LiDAR(light detection and ranging)data fusion,and architectural scene surface reconstruction and semantic modeling.We believe that it is necessary to involve multi-source data for the 3D digital preservation of ancient Chinese architecture,and that the work in this paper will serve as a heuristic guideline for the related research communities. | Xiang GAO Hainan CUI Lingjie ZHU Tianxin SHI Shuhan SHEN | 2019 | Virtual Reality & Intelligent Hardware2019，1，5： | 1 |
| 8 | Mitochondrial Dysfunction Mediates Aldosterone-Induced Podocyte Damage显示文摘 | Chunhua Zhu Songming Huang Yanggang Yuan Guixia Ding Ronghua Chen Bicheng Liu Tianxin Yang Aihua Zhang | 2011 | The American Journal of Pathology2011，，5： | 1 |
| 9 | Comparison of UV and UV-LED activated sodium percarbonate for the degradation of O-desmethylvenlafaxine显示文摘As an active metabolite of venlafaxine and emerging antidepressant,Odesmethylvenlafaxine(ODVEN) was widely detected in different water bodies,which caused potential harm to human health and environmental safety.In this study,the comparative work on the ODVEN degradation by UV(254 nm) and UV-LED(275 nm) activated sodium percarbonate(SPC) systems was systematically performed.The higher removal rate of ODVEN can be achieved under UV-LED direct photolysis(14.99%) than UV direct photolysis(4.57%) due to the higher values of photolysis coefficient at the wavelength 275nm.Significant synergistic effects were observed in the UV/SPC(80.38%) and UV-LED/SPC(53.57%) systems and the former exhibited better performance for the elimination of ODVEN.The degradation of ODVEN all followed the pseudo-first-order kinetics well in these processes,and the pseudo-first-order rate constant(kobs) increased with increasing SPC concentration.Radicals quenching experiments demonstrated that both ·OH and CO_(3)·-were involved in the degradation of ODVEN and the second-order rate constant of ODVEN with CO_(3)·-(1.58 × 10^(8)(mol/L)-1sec-1) was reported for the first time based on competitive kinetic method.The introduction of HA,Cl-,NO_(3)-and HCO_(3)-inhibited the ODVEN degradation to varying degrees in the both processes.According to quantum chemical calculation,radical addition at the ortho-position of the phenolic hydroxyl group was confirmed to be the main reaction pathways for the oxidation of ODVEN by·OH.In addition,the oxidation of ODVEN may involve the demethylation,H-abstraction,OH^(-)addition and C-N bond cleavage.Eventually,the UV-LED/SPC process was considered to be more cost-effective compared to the UV/SPC process,although the UV/SPC process possessed a higher removal rate of ODVEN. | Jing Deng Anhong Cai Xiao Ling Qian Sun Tianxin Zhu Qingsong Li Xueyan Li Weizhu Chen | 2023 | Journal of Environmental Sciences2023，，4： | 1 |
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