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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Efficacy of Banxia Xiexin decoction in a rat model of chronic atrophic gastritis显示文摘OBJECTIVE:To investigate the effectiveness of Banxia Xiexin decoction(BXD)in a rat model of chronic atrophic gastritis(CAG).METHODS:Sixty 6-week-old healthy Wistar rats(30 males,30 females)were used in the present study.A rat model of CAG was successfully established using the combined active immunization/ethanol/sodium deoxycholate method.BXD was prepared from a mixture of seven Chinese herbs,and was intragastrically administered to CAG rats at three different doses(6,12,and 24 g·kg^-1·d^-1).Af-ter 24 weeks,the rats were euthanized,and gastric tissue specimens were collected.Gastric mucosal specimens were stained with hematoxylin and eosin for histological examination to evaluate the degree of inflammation and morphological changes.Immunohistochemical staining was performed to examine the mucosal expression of proliferating cell nuclear antigen.Serum gastrin levels were measured using radioimmunoassay.The expression of Notch signaling-associated genes was examined by quantitative polymerase chain reaction and Western blot assay.RESULTS:BXD at all three doses significantly reversed the adverse effects generated by CAG in rats.Compared with control rats,the CAG rats who were administered BXD had an accelerated growth rate,reduced inflammatory cell infiltration,improved gastric mucosal morphology,augmented thickness of the gastric mucosa,increased number of gastric glands,enhanced mucosal expression of proliferating cell nuclear antigen,and elevated serum gastrin levels. | Bai Yu Chen Yongcan Chen Yu Yan Maoxiang Wei Hongquan Wang Hengcang Zeng Guoliang Yang Xiyin | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 14 |
| 3 | 声波激励的超小型纳机电系统磁电天线显示文摘当前的小型天线依赖于电磁波的谐振,因此天线的尺寸与电磁波波长相关。典型的天线尺寸大于波长的1/10,而进一步缩小天线尺寸在近十年来都是一个公开的挑战。介绍一种通过悬浮铁氧/压电薄膜异质结构的声波激励纳机械磁电天线。这种磁电天线通过其在声波谐振频率处的磁电效应接收和发射电磁波。磁电天线中的体声波激发铁磁薄膜的磁化振荡,产生电磁波的辐射;反之,天线感应电磁波的磁场,得到压电电压输出。这种磁电天线(尺寸仅为波长的千分之一)比现有小型天线的尺寸小1到2个数量级,但性能却没有降低,在便携式无线通信系统中具有很大的应用潜力。 | Tianxiang Nan Hwaider Lin Yuan Gao Alexei Matyushov Guoliang Yu Huaihao Chen Neville Sun Shengjun Wei Zhiguang Wang Menghui Li Xinjun Wang Amine Belkessam Rongdi Guo Brian Chen James Zhou Zhenyun Qian Yu Hui Matteo Rinaldi Michael E.McConney BrANDon M.Howe Zhongqiang Hu John G.Jones Gail J.Brown Nian Xiang Sun 张建强(翻译) 陈鼎鼎(审校) | 2017 | 通信对抗2017，36，4： | 8 |
| 4 | Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease: a randomized controlled clinical study显示文摘OBJECTIVE: To assess the efficacy and safety of Reduning injection for fever, rash, and ulcers in children with mild hand, foot, and mouth disease(HFMD). METHODS: A stratified-block randomized, double-blind, parallel-controlled, and multicenter clinical trial was conducted with 360 patients in five hospitals across China: Quanzhou Children's Hospital, Shijiazhuang No. 5 Hospital, Shanghai Public Health Centre, Hunan Provincial Children's Hospital, and Kaifeng Children's Hospital. Patients were randomized into three groups with 120 in each. Group A was treated with Western Medicine, group B with Reduning injection, a Chinese herbal medicine, and group C with both Reduning injection and Western Medicine. Results were compared for treatment efficacy and safety on HFMD. The clinical outcomes were observed as follows: fever and onset time of antifebrile effect(time to bring the body temperature down ≥0.5℃ after medication); cumulative time for fever recovery(body temperature recovering to normal and lasting more than 24 h without medication); cumulative time for rash disappearance(without new rashes or ulcers appearing and the original ones fading away); and cumulative time for mouth ulcer disappearance. RESULTS: For the onset time of the antifebrile effect, there was no statistical difference between groups A and B(P>0.05) and groups B and C(P> 0.05). However, there was a statistical difference between groups A and C(P<0.05), and the effect in group C was the best. For the cumulative time for rash disappearance, there was no statistical difference between groups A and B(P>0.05). There were statistical differences between groups A and C, and groups B and C(P<0.05), and the effect in group C was the best. For the cumulative time for mouth ulcers disappearance, there were no statistical differences among the three groups(P>0.05). CONCLUSION: Reduning injection with Western Medicine for symptomatic treatment is most effective for mild HFMD. No adverse reactions were observed. | Guoliang Zhang Jie Zhao Liyun He Shiyan Yan Ziqiang Zhuo Haojie Zheng Yongping Mu Shuangjie Li Xi Zhang Jihan Huang Xiuhui Li Jianping Liu Hehe Wan Chaoyu Wei Wei Xiao | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 7 |
| 5 | Microstructure and tensile properties of ultrafine grained copper processed by equal-channel angular pressing显示文摘相等隧道的尖紧迫(ECAP ) 过程被用于 12 公里 x 12 公里 x 在房间温度的纯铜(99.98 wt.%) 的 80 公里营舍。shear 变丑特征,微观结构进化,和张力的性质被调查。高力量的联合(~ 4 20 MPa ) 并且高延伸到失败(~ 2 5%) 在房间温度在八 ECAPpasses 以后被完成。与 nanocrystalline 谷物混合极其细小的谷物(~ 0 .2 μ m )(~ 8 0 nm ) 导致了高张力的力量和韧性。 | WEI Wei CHEN Guang WANG Jingtao CHEN Guoliang | 2006 | Rare Metals2006，25，6： | 4 |
| 6 | Consensus Control of Multi-Agent Systems Using Fault-Estimation-in-the-Loop:Dynamic Event-Triggered Case显示文摘The paper develops a novel framework of consensus control with fault-estimation-in-the-loop for multi-agent systems(MASs)in the presence of faults.A dynamic event-triggered protocol(DETP)by adding an auxiliary variable is utilized to improve the utilization of communication resources.First,a novel estimator with a noise bias is put forward to estimate the existed fault and then a consensus controller with fault compensation(FC)is adopted to realize the demand of reliability and safety of addressed MASs.Subsequently,a novel consensus control framework with fault-estimation-in-the-loop is developed to achieve the predetermined consensus performance with the l_(2)-l_(∞)constraint by employing the variance analysis and the Lyapunov stability approaches.Furthermore,the desired estimator and controller gains are obtained in light of the solution to an algebraic matrix equation and a linear matrix inequality in a recursive way,respectively.Finally,a simulation result is employed to verify the usefulness of the proposed design framework. | Yamei Ju Derui Ding Xiao He Qing-Long Han Guoliang Wei | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，8： | 4 |
| 7 | Comparison of the oncological,perioperative and functional outcomes of partial nephrectomy versus radical nephrectomy for clinical T1b renal cell carcinoma:A systematic review and metaanalysis of retrospective studies显示文摘Objective:To conduct a meta-analysis assessing the perioperative,functional and oncological outcomes of partial nephrectomy(PN)and radical nephrectomy(RN)for T1b tumours.The primary endpoints were the oncological outcomes.The secondary endpoints were the perioperative and functional outcomes.Methods:A systematic literature review was performed by searching multiple databases through February 2019 to identify eligible comparative studies according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement.Identified reports were assessed according to the Newcastle-Ottawa Scale for nonrandomized controlled trials.Results:Overall,13 retrospective cohort studies were included in the analysis.Patients undergoing PN were younger(weighted mean difference[WMD]3.49 years,95%confidence interval[CI]5.16 to1.82;p<0.0001)and had smaller masses(WMD0.45 cm,95%CI0.59 to0.31;p<0.0001).There were no differences in the oncological outcome,which was demonstrated by progression-free survival(hazard ratio[HR]0.70;pZ0.22),cancerspecific mortality(HR 0.91;pZ0.57)and all-cause mortality(HR 1.01;pZ0.96).The two procedures were similar in estimated blood loss(WMD16.47 mL;pZ0.53)and postoperative complications(risk ratio[RR]1.32;pZ0.10),and PN provided better renal function preservation and was related to a lower likelihood of chronic kidney disease onset(RR 0.38;pZ0.006).Conclusion:PN is an effective treatment for T1b tumours because it offers similar surgical morbidity,equivalent cancer control,and better renal preservation compared to RN. | Yucong Zhang Gongwei Long Haojie Shang Beichen Ding Guoliang Sun Wei Ouyang Man Liu Yuan Chen Heng Li Hua Xu Zhangqun Ye | 2021 | Asian Journal of Urology2021，8，1： | 4 |
| 8 | Large manipulative experiments reveal complex effects of food supplementation on population dynamics of Brandt's voles显示文摘Although food supplementation is well known to increase population density,there is still debate on the causative effects of food supplementation on reproduction,survival,and immigration.Large manipulative experiments,which exclude any confounding effects of dispersal and predation,are essential for clarifying the debate.In this study,we investigated the effects of food supplementation on Brandt's vole population dynamics and plant community in eight large enclosures(0.48 ha each) from2010 to 2014.Food supplementation showed significant positive effects on population density due to increases in recruitment;however,it showed a complex effect on survival of voles:positive in non-breeding seasons,but negative in breeding seasons.In addition,food supplementation increased the quality of plants(as reflected by increased crude protein content),but decreased the quantity of less preferred plants in experimental enclosures.Thus,food seems to have direct positive effects on small rodents through improvement of food supply and indirect negative effects through food-induced density-dependent effects,and may have long-term effects on rodents through altering plant community composition and abundance. | Baofa Yin Guoliang Li Xinrong Wan Guozhen Shang Wanhong Wei Zhibin Zhang | 2017 | Science China(Life Sciences)2017，60，8： | 4 |
| 9 | Study on the interaction between engineering construction and ecosystem changes in the Longitudinal Range-Gorge Region显示文摘这份报纸拿在作为主要科学问题设计构造和生态系统变化之间的相互作用。基于 DPSIR ( Drive-Press-State-Impact-Response )框架,这研究分析在从开车,出版社,状态,影响和反应的方面设计构造和生态系统变化之间的相互作用的通匝,向前带相互作用模型,相互作用情形分析方法和相互作用索引(开车反应索引, IIDR ,开车影响索引, IIDI ,影响反应索引,红外,影响索引, IIII ),并且预付相应计算模型和相互作用索引 sy 并且也,这份报纸采用不同相互作用索引到尊重影响在上和对设计建设的反应,并且作为例子在纵的范围峡区域(LRGR ) 拿 Manwan 水力发出的电力车站和道路交通建设分析并且验证相互作用模型。由建设的结果和 Manwan 水力发出的电力的操作的系统的分析,车站是分别地 3.67, 3.92, 14.35 和 0.35。没有在相互作用系统,和利用的通匝元素的显著变化水力发出的电力车站基于想象有益于地区性的环境和社会的持续发展没有考虑环境费用,散开效果,潜在的否定效果和潜力,水力发出的电力的回答驻扎建设。通过一些案例研究,我们造了的相互作用模型在相互作用显示出很好的实际价值量的分析并且相互作用索引系统构造。 | CUI BaoShan HU Bo ZHAI HongJuan WEI GuoLiang WANG Juan School of Environment,Beijing Normal University State Key Joint Laboratory of Environmental Simulation and Pollution Contro,Beijing 100875,China | 2007 | Chinese Science Bulletin2007，52，A02： | 3 |
| 10 | Tribological behavior of black phosphorus nanosheets as water-based lubrication additives显示文摘Black phosphorus(BP)with a layered structure has been used gradually as a lubrication additive in the tribological area.In this study,BP powders are produced via an easy method of high-energy ball milling using red phosphorus as a raw material.Subsequently,BP nanosheets are prepared via liquid exfoliation in N-methyl pyrolidone solvent.The tribological behavior of BP nanosheets as water-based lubrication additives(BP-WL)is evaluated under Ti6Al4V(TC4)/GCr15 contact.The results suggest that the 70 mg/L BP-WL sample exhibits excellent lubrication performance,whose coefficient of friction(COF)and ball wear rate reduced by 32.4%and 61.1%,respectively,compared with those of pure water.However,as the load increased,the tribological properties of BP-WL reduced gradually because of the agglomeration of BP nanosheets.Based on tribological experiments and worn surface analysis,boundary lubrication mechanisms are proposed.The friction reduced,which is primarily attributed to the low interlaminar shear and adsorption of BP nanosheets.In addition,a tribochemical reaction film comprising TiO_(2),Al_(2)O_(3),and Fe_(2)O_(3)effectively protects the surface of titanium alloy/steel from wear.This new water-based lubrication additive can be used to process titanium alloys. | Qingjuan WANG Tingli HOU Wei WANG Guoliang ZHANG Yuan GAO Kuaishe WANG | 2022 | Friction2022，10，3： | 3 |
| 11 | The research of space-time coupled spectral element method for acoustic wave equations显示文摘A space-time coupled spectral element method based on Chebyshev polynomials is presented for solving time-dependent wave equations.Acoustic propagation problems in1+1,2+1,3+1 dimensions with the Dirichlet boundary conditions are simulated via space-time coupled spectral element method using quadrilateral,hexahedral and tesseractic elements respectively.Space-time coupled spectral element method can obtain high-order precision over time.With the same total number of nodes,higher numerical precision is obtained if the higher-order Chebyshev polynomials in space directions and lower-order Chebyshev polynomials in time direction are adopted.Numerical illustrations have indicated that the space-time algorithm provides higher precision than the semi-discretization.When space-time coupled spectral element method is used,time subdomain-by-subdomain approach is more economical than time domain approach. | GENG Yanhui QIN Guoliang WANG Yang HE Wei | 2016 | Chinese Journal of Acoustics2016，35，1： | 3 |
| 12 | Calculation of Temperature Field During Laser Transformation Hardening of Cylindrical Bodies显示文摘A Two-dimensional transient heat transfer model for laser transformation hardening process of cylindrical bodies has been developed. The surface heat loss of the sample, the latent heat of phase transformation, and the temperature dependence of thermal properties of material were considered. The laser heat source was considered as a moving Gaussian heat flux with a constant velocity. Finite element method was used to calculate the transient temperature field. A program to calculate the temperature field was developed using FORTRAN language. The transient temperature field, the width and depth of laser transformation hardening zone of 42CrMo steel sample during laser transformation hardening process was calculated. The widths and depths of laser transformation hardening zones of 42CrMo steel samples were also measured experimentally. The calculated widths and depths of laser transformation hardening zones are in good agreement with the experimental results. | Liwen Zhang, Lixia Wei Guoliang Zhang, J. Th.MDe Hosson Yuanliang Xia , Fugang Wang 1.The State Key Laboratory for Materials Modification by Laser, Ion and Electron Beams 2.Material Engineering Department of Dalian University of Technology, Dalian 11 60 | 2000 | Journal of Shanghai Jiaotong university(Science)2000，5，1： | 3 |
| 13 | Research Progress on Agrobacterium tumefaciens-based Transgenic Technology in Brassica rapa显示文摘Brassica rapa L.is cultivated globally and consumed in many areas worldwide.Using the transgenic Agrobacterium-mediated transformation method,which is a reproducible and efficient technique,genes can be transferred into various B.rapa species.This review summarizes the processes involved in Agrobacterium-mediated transformation of B.rapa,including surface seed sterilization,co-cultivation with A.tumefaciens,induction of callus/shoot/root formation,and confirmation of transgenic plants.In addition,factors such as the Agrobacterium strain,plant genotype,explant age,transformation efficiency of the hybrid or inbred line,and the concentrations of N6-benzyl amino purine and naphthalene acetic acid,are discussed.And this review shows clearly how to do it,what to do,and what not to do in the transgenic Agrobacterium-mediated in Brassica rapa.The information presented here lays the foundation for a simple and efficient method that resolves existing problems and improves overall transgenic B.rapa production,thereby benefiting both basic and applied research. | LI Guoliang YUE Lixin LI Fei ZHANG Shifan ZHANG Hui QIAN Wei FANG Zhiyuan WU Jian WANG Xiaowu ZHANG Shujiang SUN Rifei | 2018 | Horticultural Plant Journal2018，4，3： | 3 |
| 14 | A small scale expression screen identifies tissue specific markers in the Dugesia japonica strain Pek-1显示文摘Freshwater planaria has tremendous capacity to reform the missing part of the body and therefore is considered as one of the most important model organism for regeneration study. At present, Schmidtea mediterranea and Dugesia japonica are the two major species utilized for laboratory manipulations. Dugesia japonica flatworms are widely distributed in the Far East including Cherry Valley region in the northwest area of Beijing, China. We reported here the establishment of an asexual Dugesia japonica strain Pek1, as a suitable system for regeneration study. Using morphological, karyotypical as well as phylogenetic analyses, we confirmed that these flatworms indeed belonged to Dugesia japonica. We went on to show that the commonly used in situ probes and immunohistochemistry reagents and protocols were applicable to the Pek1 strain. Using this strain, we carried out small scale analysis on EST, RNAi and gene expression. We identified 193 unique EST sequences and 65 of them had not been reported in planarian. By RNAi analysis, we showed that 48 genes, when downregulated individually, had no effect on regeneration. Furthermore, we identified 3 groups of tissue specific expressing genes that were useful for cell lineage analysis. We concluded that the Dugesia japonica Pek1 strain could be another suitable animal model to regeneration research. | Changxin Ma Xiaoan Wang Shuizhou Yu Guoliang Chai Hanxia Su Liang Zheng Wei Wu | 2010 | Journal of Genetics and Genomics2010，37，9： | 3 |
| 15 | AN UTILITIES BASED APPROACH FOR MULTI-PERIOD DYNAMIC PORTFOLIO SELECTION显示文摘这篇论文建议了一个多时期动态最佳的公事包选择模型。假设被做保证推理的严格。这条途径描绘了开发;真实证券市场变化;是一次尝试补救一些最近的研究的缺乏。模型是二次的编程的一种标准形式。而且,这篇论文在真实证券市场论述了一个数字例子。 | Guoliang YANG Siming HUANG Wei CHEN | 2007 | Journal of Systems Science and Systems Engineering2007，16，3： | 2 |
| 16 | Association of a single nucleotide polymorphism at 6q25.1, rs2046210, with endometrial cancer risk among Chinese women显示文摘A recent genome-wide association study identified a new susceptibility locus for breast cancer, rs2046210, which is a single nucleotide polymorphism (SNP) located upstream of the estrogen receptor α (ESR1) gene on chromosome 6q25.1. Given that endometrial cancer shares many risk factors with breast cancer and both are related to estrogen exposure and that rs2046210 is in close proximity to the ESR1 gene, we evaluated the association of SNP rs2046210 with endometrial cancer risk among 953 cases and 947 controls in a population-based, case-control study conducted in Shanghai, China. Logistic regression models were used to derive odds ratios (ORs) and 95% confidence intervals (95% CIs) after adjusting for potential confounders. We found that the A allele of rs2046210, linked to an increased risk of breast cancer, was associated with increased but not statistically significant risk of endometrial cancer (OR = 1.16, 95% CI = 0.96-1.41 for the GA and AA genotypes compared with the GG genotype); the association was stronger among post-menopausal women (OR = 1.28, 95% CI = 1.00-1.65). The association tended to be stronger among women with higher or longer estrogen exposure than among women with relatively lower or shorter exposure to estrogen. Our study suggests that rs2046210 may play a role in the etiology of endometrial cancer. Additional studies are needed to confirm our findings. | Guoliang Li Yong-Bing Xiang Regina Courtney Jia-Rong Cheng Bo Huang Ji-Rong Long Hui Cai Wei Zheng Xiao-Ou Shu Qiuyin Cai | 2011 | Chinese Journal of Cancer2011，30，2： | 2 |
| 17 | A series of novel Zn(Ⅱ) and Mn(Ⅱ) metal-organic frameworks constructed by 2,4-bis-oxyacetate-benzoic acid: syntheses, structures and photoluminescence显示文摘A new carboxylic acid ligand, 2,4-bis-oxyacetate-benzoic acid(H3BOABA), was designed and introduced to construct novel metal-organic framework materials. [Zn Na(BOABA)(phen)(H2O)]·H2O(1), Zn Na(BOABA)(2), Mn3(BOABA)2(phen)2(3), [Mn2(BOABA)(OH)]·(H2O)2(4)(CCDC: 885138, 885137, 894225, 883094) were hydrothermally synthesized and characterized by elemental analysis, IR spectra and thermal gravimetric analyses. Crystal structures of the complexes were determined by single crystal X-ray diffraction method. Complex 1 is a one dimensional double edges non-interpenetrated framework decorated by the phen ligands on the surface. Complex 2 is an unique three dimensional open framework, consisting of Zn(II) and Na(I). Complex 3 is an unique double edges one dimensional MOF containing a [Mn3(BOABA)2(phen)2]n non-interpenetrated structure. Complex 4 is a two dimensional plane structure containing two Mn atoms in the same coordination environment. The interaction between four complexes and DNA were studied by Et Br fluorescence probe. Meanwhile, photoluminescence studies revealed that these four complexes display strong fluorescent emission bands in the solid state at room temperature. | Yan Lv Pei Shi Wei Shen Xiaoju Chen Guoliang Zhao | 2015 | Science China Chemistry2015，58，3： | 2 |
| 18 | Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis显示文摘Impairment of glucose(Glu)uptake and storage by skeletal muscle is a prime risk factor for the development of metabolic diseases.Heterogeneous nuclear ribonucleoprotein A1(hnRNP Al)is a highly abundant RNA-binding protein that has been implicated in diverse cellular functions.The aim of this study was to investigate the function of hnRNP A1 on muscle tissue insulin sensitivity and systemic Glu homeostasis.Our results showed that conditional deletion of hnRNP Al in the muscle gave rise to a severe insulin resistance phenotype in mice fed a high-fat diet(HFD).Conditional knockout mice fed a HFD showed exacerbated obesity,insulin resistance,and hepatic steatosis.In vitro interference of hnRNP Al in C2C12 myotubes impaired insulin signal transduction and inhibited Glu uptake,whereas hnRNP Al overexpression in C2C12 myotubes protected against insulin resistance induced by supraphysiological concentrations of insulin.The expression and stability of glycogen synthase(gysl)mRNA were also decreased in the absence of hnRNP A l.Mechanistically,hnRNP Al interacted with gys l and stabilized its mRNA,thereby promoting glycogen synthesis and maintaining the insulin sensitivity in muscle tissue.Taken together,our findings are the first to show that reduced expression of hnRNP Al in skeletal muscle affects the metabolic properties and systemic insulin sensitivity by inhibiting glycogen synthesis. | Mingxia Zhao Lihong Shen Zijun Ouyang Manru Li Guoliang Deng Chenxi Yang Wei Zheng Lingdong Kong Xuefeng Wu Xudong Wu Wenjie Guo Ye Yin Qiang Xu Yang Sun | 2020 | Journal of Molecular Cell Biology2020，12，4： | 2 |
| 19 | Fixing, preventing, and recovering from concurrency bugs显示文摘Concurrency bugs are becoming widespread with the emerging ubiquity of multicore processors and multithreaded software. They manifest during production runs and lead to severe losses. Many effective concurrency-bug detection tools have been built. However, the dependability of multi-threaded software does not improve until these bugs are handled statically or dynamically. This article discusses our recent progresses on fixing, preventing, and recovering from concurrency bugs. | DENG DongDong JIN GuoLiang de KRUIJF Marc LI Ang LIBLIT Ben LU Shan QI ShanXiang REN JingLei SANKARALINGAM Karthikeyan SONG LinHai WU YongWei ZHANG MingXing ZHANG Wei ZHENG WeiMin | 2015 | Science China(Information Sciences)2015，58，5： | 2 |
| 20 | External stimuli controlled multiferroic charge-transfer crystals显示文摘Multiferroic 费用转移晶体拉了重要兴趣由于他们的同时偶极并且订的纺纱。众多的理论、试验性的研究证明了在施主和领受人建筑群之间的分子的叠在调节费用转移起一个重要作用启用的 multifunctionality。此处,我们证明费用转移相互作用能被分离的栈控制,由 polythiophene 施主组成 -- 并且 fullerene 基于领受人的结合所有的块共聚物。房间温度磁场效果,铁电性,和各向异性的磁力在费用转移晶体被观察,它能被 photoexcitation 并且充电做进一步控制。而且,费用转移分离了栈晶体证明外部刺激控制了极化和磁化,它为所有器官的 multiferroics 开创他们的多功能的应用程序。 | Wei Qin Xiaomin Chen Jessica Lohrman Maogang Gong Guoliang Yuan Manfred Wuttig Shenqiang Ren | 2016 | Nano Research2016，9，4： | 2 |
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