|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Characterization and fine mapping of the rice blast resistance gene Pia显示文摘Blast,caused by Magnaporthe oryzae,is one of the most widespread and destructive diseases of rice.Breeding durable resistant cultivars(cvs) can be achieved by pyramiding of various resistance(R) genes.Pia,carried by cv.Aichi Asahi,was evaluated against 612 isolates of M.oryzae collected from 10 Chinese provinces.The Pia gene expresses weak resistance in all the provinces except for Jiangsu.Genomic position-ready marker-based linkage analysis was carried out in a mapping population consisting of 800 F2 plants derived from a cross of Aichi Asahi×Kasalath.The locus was defined in an interval of approximately 90 kb,flanked by markers A16 and A21.Four candidate genes(Pia-1,Pia-2,Pia-3,and Pia-4) ,all having the R gene conserved structure,were predicted in the interval using the cv.Nipponbare genomic sequence.Four candidate resistance gene(CRG) markers(A17,A25,A26,and A27) ,derived from the four candidates,were subjected to genotyping with the recombinants detected at the flanking markers.The first three markers completely co-segregated with the Pia locus,and the fourth was absent in the Aichi Asahi genome and disordered with the Pia locus and its flanking markers,indicating that the fourth candidate gene,Pia-4,could be excluded.Co-segregation marker-based genotyping of the three sets of differentials with known R gene genotypes revealed that the genotype of A26(Pia-3) perfectly matched the R gene genotype of Pia,indicating that Pia-3 is the strongest candidate gene for Pia. | ZENG XiaoShan YANG XianFeng ZHAO ZhengHong LIN Fei WANG Ling PAN QingHua | 2011 | Science China(Life Sciences)2011，54，4： | 13 |
| 2 | Structural basis for the recognition of Asef by adenomatous polyposis coli显示文摘Adenomatous polyposis coli (APC ) 通过激活刺激 APC 的 guanine 核苷酸交换因素调整房间房间粘附和房间移植(GEF;Asef ) ,它通常是通过在它的 Src 相同之间的绑定的 autoinhibited 3 (SH3 ) 并且 Dbl 相同(DH ) 领域。激活 APC 的 Asef 刺激小 GTPase Cdc42,它导致减少的房间房间坚持和提高的房间移植。在 colorectal 癌症,组成地截断了 APC 激活 Asef 并且支持癌症房间移植和 angiogenesis。这里,我们报导人的 APC/Asef 建筑群的水晶结构。我们发现 APC 的犰狳重复域使用一条高度保存的表面沟认出 Asef 的 APC 有约束力的区域(ABR ) ,哪个在绑定之上戏剧性地改变到 APC 的符合构造。为复杂形成的 APC 和 Asef 上的关键残余被变异,他们的重要性被绑定和活动试金表明。有 autoinhibited Asef 的 APC/Asef 建筑群的结构的重迭建议在 APC 和 Asef 之间的绑定可能创造在 Asef-DH 领域和 APC 之间的位的碰撞,它可能在刺激它的 GEF 活动的 Asef 导致一个 conformational 变化。我们的结构因此阐明由 APC 的 Asef 识别的分子的机制,以及对癌症为药品的干预提供一个潜在的目标。 | Zhenyi Zhang Leyi Chen Lei Gao Kui Lin Liang Zhu Yang Lu Xiaoshan Shi Yuan Gao Jing Zhou Ping Xu Jian Zhang Geng Wu | 2012 | Cell Research2012，22，2： | 5 |
| 3 | Evaluation of bond stress-slip models for FRP reinforcing bars in concrete显示文摘 | Lin Xiaoshan Zhang Y X | 2014 | Composite Structures2014，107，： | 1 |
| 4 | A C-tree decomposition algorithm fir 2D and 3D geometric Gnnstraint solving显示文摘 | Gad Xiaoshan Lin Qiang Zhang Guifang | 2006 | Computer- Aided Design2006，38，1： | 1 |
| 5 | Comparative toxicity of several metal oxide nanoparticle aque-ous suspensions to zebrafish (Danio rerio) early developmental stage 显示文摘 | ZHU XIAOSHAN ZHU LIN DUAN ZHENGHUA | 2008 | Environmental Science and Health2008，43，3： | 1 |
| 6 | Comparative toxicity of several metal oxide nanoparticle aqueous suspensions to zebrafish (Danio rerio) early developmental stage显示文摘 | ZHU Xiaoshan ZHU Lin DUAN Zhenghua | 2008 | Environmental Science and Health2008，43，3： | 1 |
| 7 | Wearable membranes from zirconium-oxo clusters cross-linked polymer networks for ultrafast chemical warfare agents decontamination显示文摘The urgent need for immediate personal protection against chemical warfare agents(CWAs)spurs the requirement on robust and highly efficient catalytic systems that can be conveniently integrated to wearable devices.Herein,as a new concept for CWA decontamination catalyst design,sub-nanoscale,catalytically active zirconium-oxo molecular clusters are covalently integrated in flexible polymer network as crosslinkers for the full exposure of catalytic sites as well as robust framework structures.The obtained membrane catalysts exhibit high swelling ratio with aqueous content as 84 wt%and therefore,demonstrate quasi-homogeneous catalytic activity toward the rapid hydrolysis of both CWA,soman(GD)(t_(1/2)=5.0 min)and CWA simulant,methyl paraoxon(DMNP)(t_(1/2)=8.9 min).Meanwhile,due to the covalent nature of cross-linkages and the high flexibility of polymer strands,the membranes possess promising mechanical strength and toughness that can stand the impact of high gas pressures and show high permeation for both CO_(2)and O_(2),enabling their extended applications in the field of collective/personal protective materials with body comfort. | Litao Ma Jiamin Xie Xiaoshan Yan Zhiwei Fan Heguo Li Lin Lu Likun Chen Yi Xin Panchao Yin | 2022 | Chinese Chemical Letters2022，33，6： | 1 |
| 8 | Acute toxieities of six manufactured nanomaterial suspensions to Daphnia magna 显示文摘 | ZHU Xiaoshan ZHU Lin CHEN Yongsheng | 2009 | Journal of Nanoparticle Research2009，11，1： | 1 |
| 9 | Effects of long-term exposure to TDCPP in zebrafish( Danio rerio )–Alternations of hormone balance and gene transcriptions along hypothalamus-pituitary axes显示文摘Background : TDCPP is one of the major chemical of organophosphate flame retardants(OPFRs) that has been detected ubiquitously in both the environment and biota. Previously we observed that it influenced the concentrations of sex and thyroid hormones in a sex-dependent pattern, leading to reproductive impairments after short-term exposure in zebrafish. Here we investigate the consequences of longerterm exposure to TDCPP on the hypothalamic-pituitary-gonad(HPG), hypothalamicpituitary-i nterrenal(HPI), and hypothalamic-pituitary-thyroid(HPT) axes of zebrafish( Danio rerio).Methods : A 120-day exposure test to 0.005, 0.05 and 0.5 mg/L TDCPP was initiated with fertilized eggs. Sex steroid hormones in the treated fishes were measured and transcriptional changes were analyzed.Results : In female fish, exposure to TDCPP resulted in increases in plasma cortisol,follicle stimulating hormone(FSH), luteinizing hormone(LH), 17β-estradiol(E2), cortisol, thyroxine(T4), and triiodothyronine(T3). Transcription of most target genes along HPG, HPI and HPT axes were increased by the exposure. While in male fish the exposure led to decreases in cortisol, FSH, LH, T4, T3, testosterone(T), and 11-ketotestosterone(11-KT). Transcription of genes along HPG, HPI and HPT axes,especially steroidogenic genes, were inhibited in male zebrafish. While, E2/T or E2/11-KT ratio was increased in both female and females. The sex-dependent changes in hormones might be due to differential responses to TDCPP induced stresses. An increase in cortisol level coincided with increases in E2 and THs in female fish, while in males decreases in cortisol as well as T, 11-KT and THs were observed. Long-term exposure to TDCPP at very low(μg/L) concentrations could disrupt hormone balances in a sex dependent way.Conclusion : This study revealed that TDCPP could affect endocrine axes – HPG, HPI and HPT – in zebrafish, and impair zebrafish development. | Xiaoshan Liu Xiaoxun Lu Jiabin Hong Jing Zhang Juntong Lin Mengzhu Jiang Qian Liu Kyungho Choi Jingjing Zhang | 2022 | Animal Models and Experimental Medicine2022，5，3： | 1 |
| 10 | Bond-slip behavior of FRP-reinforced concrete beams 显示文摘 | Lin Xiaoshan Zhang Y X | 2013 | 44:110-1172013，44，： | 1 |
| 11 | N-doped CoAl oxides from hydrotalcites with enhanced oxygen vacancies for excellent low-temperature propane oxidation显示文摘A series of nitrogen-doped CoAlO(N-CoAlO)were constructed by a hydrothermal route combined with a controllable NH_(3) treatment strategy.The effects of NH_(3) treatment on the physico-chemical properties and oxidation activities of N-Co AlO catalysts were investigated.In comparison to CoAlO,a smallest content decrease in surface Co^(3+)(serving as active sites)while a largest increased amount of surface Co^(2+)(contributing to oxygen species)are obtained over N-Co AlO/4h among the N-CoAlO catalysts.Meanwhile,a maximum N doping is found over N-CoAlO/4h.As a result,N-CoAlO/4h(under NH_(3) treatment at 400℃ for 4 hr)with rich oxygen vacancies shows optimal catalytic activity,with a T90(the temperature required to reach a 90% conversion of propane)at 266℃.The more oxygen vacancies are caused by the co-operative effects of N doping and suitable reduction of Co^(3+) for NCoAlO/4h,leading to an enhanced oxygen mobility,which in turn promotes C_(3)H_(8) total oxidation activity dominated by Langmuir-Hinshelwood mechanism.Moreover,in situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTs)analysis shows that N doping facilities the decomposition of intermediate species(propylene and formate)into CO_(2)over the catalyst surface of N-CoAlO/4h more easily.Our reported design in this work will provide a promising way to develop abundant oxygen vacancies of Co-based catalysts derived from hydrotalcites by a simple NH_(3) treatment. | Enhui Wu Daifeng Lin Yinye Chen Xiaoshan Feng Kui Niu Yongjin Luo Baoquan Huang Jianbin Qiu Qingrong Qian Qinghua Chen | 2022 | Journal of Environmental Sciences2022，34，6： | 0 |
| 12 | KDM2B能够依赖其招募PRC1.1复合物的功能调控体细胞重编程显示文摘文章简介PRC1(Polycomb Repressive Complex 1)复合物在发育过程中起着非常重要的作用,很多复合物成分的缺失或者异常都能直接导致胚胎发育的异常。最近的研究发现PRC1包含多种变体,但是其对细胞命运调控的具体机制并不十分清楚。 | Zhiwei Zhou Xuejie Yang Jiangping He Jing Liu Fang Wu Shengyong Yu Yuting Liu Runxia Lin He Liu Yuanbin Cui Chunhua Zhou Xiaoshan Wang Jian Wu Shangtao Cao Lin Guo Lihui Lin Tao Wang Xiaozhong Peng Boqing Qiang Andrew P.Hutchins 裴端卿 陈捷凯 | 2018 | 科学新闻2018，0，4： | 0 |
| 13 | Optical spectroscopy study of Ca_3(Ru_(0.91)Mn_(0.09))_2O_7 single crystal in high magnetic fields显示文摘The magneto-optical spectrum, with magnetic fields up to 42 T, of double layered ruthenates Ca_3(Ru_(0.91)Mn_(0.09))_2O_7(CRMO) single crystal is studied. Both the temperature and magnetic field induced insulator-to-metal transitions(IMTs) are observed via magneto-optical properties of the crystal. The critical magnetic field(H//c) of IMT for CRMO is found to be as large as 35 T at 5 K. The fine structure of optical spectra identified the antiferromagnetic/ferro-orbital-ordering configurations of Ru 4d orbitals at low temperatures. Meanwhile, the configuration of orbital polarization of such double-layer CRMO single crystal is discussed. These results suggest that the orbital degree of freedom plays an important role in the field induced IMT of multi-orbital system. | Xueli Xu Jin Peng Junpei Zhang Zongwei Ma Cheng Chen Junbo Han Bingjie Liu Lingfang Lin Xiaoshan Wu Zhiqiang Mao Zhe Qu Zhigao Sheng | 2019 | Science Bulletin2019，64，1： | 0 |
| 14 | Ultrasmall Ru nanoparticles supported on chitin nanofibers for hydrogen production from NaBH4 hydrolysis显示文摘In this work,a series of chitin-supported Ru catalysts,composed of ultrasmall Ru nanoparticles supported on the chitin nanofibers,with different Ru content from 0.07 wt%to 0.93 wt%,are fabricated.Results from catalyzed NaBH4 hydrolysis experiments indicate that the catalytic activity of the fabricated chitin-supported Ru catalysts increases gradually with the decreasing of Ru content.The rate of hydrogen generation from NaBH4 hydrolysis catalyzed by the catalyst with 0.07 wt%Ru content is as high as 55.29 L min 1 gRu-1 at 30℃,and this reaction exhibits activation energy of 39.16 kJ/mol.The augment of NaBH4 dosage in the experiments does not weaken the catalytic activity.In addition,the fabricated chitin-supported Ru catalysts show excellent durability in NaBH4 hydrolysis,with only 9.2%activity loss after used for 20 cycles.With excellent catalytic activity and durability,the as-obtained Ru catalysts provide a promising choice for promoting hydrogen production from NaBH4 hydrolysis. | Jiapeng Zhang Fanzhen Lin Lijing Yang Zhaoyi He Xiaoshan Huang Dingwei Zhang Hua Dong | 2020 | Chinese Chemical Letters2020，31，7： | 0 |
| 15 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 16 | Layout optimization of steel reinforcement in concrete structure using a truss-continuum model显示文摘Owing to advancement in advanced manufacturing technology,the reinforcement design of concrete structures has become an important topic in structural engineering.Based on bi-directional evolutionary structural optimization(BESO),a new approach is developed in this study to optimize the reinforcement layout in steel-reinforced concrete(SRC)structures.This approach combines a minimum compliance objective function with a hybrid trusscontinuum model.Furthermore,a modified bi-directional evolutionary structural optimization(M-BESO)method is proposed to control the level of tensile stress in concrete.To fully utilize the tensile strength of steel and the compressive strength of concrete,the optimization sensitivity of steel in a concrete–steel composite is integrated with the average normal stress of a neighboring concrete.To demonstrate the effectiveness of the proposed procedures,reinforcement layout optimizations of a simply supported beam,a corbel,and a wall with a window are conducted.Clear steel trajectories of SRC structures can be obtained using both methods.The area of critical tensile stress in concrete yielded by the M-BESO is more than 40%lower than that yielded by the uniform design and BESO.Hence,the M-BESO facilitates a fully digital workflow that can be extremely effective for improving the design of steel reinforcements in concrete structures. | Anbang CHEN Xiaoshan LIN Zi-Long ZHAO Yi Min XIE | 2023 | Frontiers of Structural and Civil Engineering2023，17，5： | 0 |
| 17 | Realization of Oriented and Nanoporous Bismuth Chalcogenide Layers via Topochemical Heteroepitaxy for Flexible Gas Sensors显示文摘Most van der Waals two-dimensional(2D)materials without surface dangling bonds show limited surface activities except for their edge sites.Ultrathin Bi_(2)Se_(3),a topological insulator that behaves metal-like under ambient conditions,has been overlooked on its surface activities.Herein,through a topochemical conversion process,ultrathin nanoporous Bi_(2)Se_(3) layers were epitaxially deposited on BiOCl nanosheets with strong electronic coupling,leading to hybrid electronic states with further bandgap narrowing.Such oriented nanoporous Bi_(2)Se_(3) layers possessed largely exposed active edge sites,along with improved surface roughness and film forming ability even on inkjet-printed flexible electrodes.Superior room-temperature NO_(2) sensing performance was achieved compared to other 2D materials under bent conditions.Our work demonstrates that creating nanoscale features in 2D materials through topochemical heteroepitaxy is promising to achieve both favorable electronic properties and surface activity toward practical applications. | Zhiwei Wang Jie Dai Jian Wang Xinzhe Li Chengjie Pei Yanlei Liu Jiaxu Yan Lin Wang Shaozhou Li Hai Li Xiaoshan Wang Xiao Huang Wei Huang | 2022 | Research2022，，4： | 0 |
| 18 | FBXW7βloss-of-function enhances FASN-mediated lipogenesis and promotes colorectal cancer growth显示文摘Continuous de novo fatty acid synthesis is required for the biosynthetic demands of tumor.FBXW7 is a highly mutated gene in CRC,but its biological functions in cancer are not fully characterized.Here,we report that FBXW7β,a FBXW7 isoform located in the cytoplasm and frequently mutated in CRC,is an E3 ligase of fatty acid synthase(FASN).Cancer-specific FBXW7βmutations that could not degrade FASN can lead to sustained lipogenesis in CRC.COP9 signalosome subunit 6(CSN6),an oncogenic marker of CRC,increases lipogenesis via interacting with and stabilizing FASN.Mechanistic studies show that CSN6 associates with both FBXW7βand FASN,and antagonizes FBXW7β’s activity by enhancing FBXW7βautoubiquitination and degradation,which in turn prevents FBXW7β-mediated FASN ubiquitination and degradation,thereby regulating lipogenesis positively.Both CSN6 and FASN are positively correlated in CRC,and CSN6-FASN axis,regulated by EGF,is responsible for poor prognosis of CRC.The EGF-CSN6-FASN axis promotes tumor growth and implies a treatment strategy of combination of orlistat and cetuximab.Patient-derived xenograft experiments prove the effectiveness of employing orlistat and cetuximab combination in suppressing tumor growth for CSN6/FASN-high CRC.Thus,CSN6-FASN axis reprograms lipogenesis to promote tumor growth and is a target for cancer intervening strategy in CRC. | Wenxia Wei Baifu Qin Weijie Wen Boyu Zhang Haidan Luo Yuzhi Wang Hui Xu Xiaoshan Xie Sicheng Liu Xin Jiang Mengan Wang Qin Tang Jiayu Zhang Runxiang Yang Zongmin Fan Haiwen Lyu Junzhong Lin Kai Li Mong-Hong Lee | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 0 |
| 19 | “Purchasing hope”:the consumption of children’s education in urban China显示文摘Children’s education has become an important part of urban family consumption,and the rapid expansion of private tutoring schools and supplemental lessons has constituted a big part of the children’s education market.Taking the perspective of family studies and using China Education Panel Survey(2013-2014)data,this paper explores the relationship between family structure,parenthood,and the consumption of children’s education.This research shows that family investment in children’s education exhibits dual characteristics of instrumental rationality and emotional expression;children from one-child families,living with both parents and receiving more attention and affection from their parents,have more educational opportunities outside of school;girls receive more advantage over boys.Meanwhile,social class differences in the consumption of children’s education are significant.Middle-class families have greater education expectation and will invest more in children’s education,displaying a significantly stratified preference in supplemental lessons.These findings illustrate the need to take a new look at family studies and consumption research regarding the issue of child education consumption in the future. | Xiaoshan Lin | 2019 | The Journal of Chinese Sociology2019，6，1： | 0 |
| 20 | A Novel Approach for Identifying the Heme-Binding Proteins from Mouse Tissues显示文摘Heme is a key cofactor in aerobic life, both in eukaryotes and prokaryotes. Because of the high reactivity of ferrous protoporphyrin IX, the reactions of heme in cells are often carried out through heme-protein complexes. Traditionally studies of hemebinding proteins have been approached on a case by case basis, thus there is a limited global view of the distribution of heme-binding proteins in different cells or tissues. The procedure described here is aimed at profiling hemne-binding proteins in mouse tissues sequentially by 1) purification of heme-binding proteins by hemeagarose, an affinity chromatographic resin; 2) isolation of heme-binding proteins by SDS-PAGE or two-dimensional electrophoresis; 3) identification of heme-binding proteins by mass spectrometry. In five mouse tissues, over 600 protein spots were visualized on 2DE gel stained by Commassie blue and 154 proteins were identified by MALDI-TOF, in which most proteins belong to heme related. This methodology makes it possible to globally characterize the heme-binding proteins in a biological system. | Xiaolei Li, Xiaoshan Wang, Kang Zhao, Zhengfeng Zhou, Caifeng Zhao, Ren Yan, Liang Lin, Tingting Lei, Jianning Yin, Rong Wang, Zhongsheng Sun, Znyuan Xu, Jingyue Bao, Xiuqing Zhang, Xiaoli Feng, and Siqi Liu* Beijing Genomics Institute, Chinese Academy of Sciences Beijing 101300, China | 2003 | Genomics, Proteomics & Bioinformatics2003，1，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员