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| 1 | The Tartary Buckwheat Genome Provides Insights into Rutin Biosynthesis and Abiotic Stress Tolerance显示文摘 | Zhang, Lijun Li, Xiuxiu Ma, Bin Gao, Qiang Du, Huilong Han, Yuanhuai Li, Yan Cao, Yinghao Qi, Ming Zhu, Yaxin Lu, Hongwei Ma, Mingchuan Liu, Longlong Zhou, Jianping Nan, Chenghu Qin, Yongjun Wang, Jun Cui, Lin Liu, Huimin Liang, Chengzhi Qiao, Zhijun | 2017 | Molecular Plant2017，10，9： | 53 |
| 2 | Transmission Dynamics of an Outbreak of the COVID-19 Delta Variant B.1.617.2——Guangdong Province,China,May-June 2021显示文摘On May 21,2021,a local case of coronavirus disease 2019(COVID-19)was confirmed in a 75-year-old woman(experienced onset of symptoms on May 18)in Liwan District,Guangzhou City,Guangdong Province,China.The number of infections has increased in the following 10 days and led to 5 generations of transmission. | Meng Zhang Jianpeng Xiao Aiping Deng Yingtao Zhang Yali Zhuang Ting Hu Jiansen Li Hongwei Tu Bosheng Li Yan Zhou Jun Yuan Lei Luo Zimian Liang Youzhi Huang Guoqiang Ye Mingwei Cai Gongli Li Bo Yang Bin Xu Ximing Huang Yazun Cui Dongsheng Ren Yanping Zhang Min Kang Yan Li | 2021 | China CDC weekly2021，3，27： | 51 |
| 3 | Field experiment on a robust hierarchical metropolitan quantum cryptography network显示文摘A hierarchical metropolitan quantum cryptography network upon the inner-city commercial telecom fiber cables is reported in this paper. The seven-user network contains a four-node backbone net with one node acting as the subnet gateway, a two-user subnet and a single-fiber access link, which is realized by the Faraday-Michelson interferometer set-ups. The techniques of the quantum router, optical switch and trusted relay are assembled here to guarantee the feasibility and expandability of the quantum cryptography network. Five nodes of the network are located in the government departments and the secure keys generated by the quantum key distribution network are utilized to encrypt the instant video, sound, text messages and confidential files transmitting between these bureaus. The whole implementation including the hierarchical quantum cryptographic communication network links and the corresponding application software shows a big step toward the practical user-oriented network with a high security level. | XU FangXing CHEN Wei WANG Shuang YIN ZhenQiang ZHANG Yang LIU Yun ZHOU Zheng ZHAO YiBo LI HongWei LIU Dong HAN ZhengFu GUO GuangCan | 2009 | Chinese Science Bulletin2009，54，17： | 40 |
| 4 | Strategies of minimally invasive treatment for intrahepatic and extrahepatic bile duct stones显示文摘 | Zongming Zhang Zhuo Liu Limin Liu Mengmeng Song Chong Zhang Hongwei Yu Baijiang Wan Mingwen Zhu Zixu Liu Hai Deng Haiming Yuan Haiyan Yang Wenping Wei Yue Zhao | 2017 | Frontiers of Medicine2017，11，4： | 37 |
| 5 | Coordinated regulation of apical hook development by gibberellins and ethylene in etiolated Arabidopsis seedlings显示文摘当在土壤发芽时,当通过土壤耸出时,黑暗成年的 Arabidopsis 幼苗开发一个顶端的钩,它保护子叶和顶端的 meristematic 纸巾。几荷尔蒙被报导清楚地调制这个过程。以前的研究证明了乙烯和赤霉素(气体) 并列地调整钩发展,尽管内在的分子的机制大部分是未知的。当 paclobutrazol 镇压了时,这里,我们显示出提高的那 GA 3 ethylene-overexpression 和 EIN3-overexpression (EIN3ox ) 导致了钩弯曲,并且 della 异种展出了夸大的钩弯曲,它要求了发信号的未经触动的乙烯小径。基因学习表明那提高 GA 的钩开发依赖于无钩 1 (HLS1 ) ,调停的一个中央管理者多重发信号小径的输入在顶端的钩开发期间。我们进一步发现那 GA 3 导致(并且 DELLA 蛋白质镇压了) 在乙烯感觉迟钝的 3/EIN3-LIKE 的 HLS1 表示 1 (EIN3/EIL1 ) 依赖举止, EIN3/EIL1 由此激活 HLS1 抄写由对它的倡导者直接有约束力。另外, DELLA 蛋白质被发现与 EIN3/EIL1 的 DNA 有约束力的领域交往并且镇压 EIN3/EIL1-regulated HLS1 表示。有 naphthylphthalamic 酸的处理,一个极的植物生长素运输禁止者,镇压 EIN3ox 线的组成地夸大的钩弯曲和 della 异种,支持那植物生长素在钩开发乙烯和 GA 小径下游地工作。一起拿,我们的结果作为联系 DELLA 的抄写因素的一个新类识别 EIN3/EIL1 并且证明 GA 由经由 EIN3/EIL1 函数的 derepression 导致 HLS1 的表达式部分与乙烯在合作支持顶端的钩形成。 | Fengying An Xing Zhang Ziqiang Zhu Yusi Ji Wenrong He Zhiqiang Jiang Mingzhe Li Hongwei Guo | 2012 | Cell Research2012，22，5： | 34 |
| 6 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 7 | Correction of β-thalassemia mutant by base editor in human embryos显示文摘 | Puping Liang Chenhui Ding Hongwei Sun Xiaowei Xie Yanwen Xu Xiya Zhang Ying Sun Yuanyan Xiong Wenbin Ma Yongxiang Liu Yali Wang Jianpei Fang Dan Liu Zhou Songyang Canquan Zhou Junjiu Huang | 2017 | Protein & Cell2017，8，11： | 34 |
| 8 | Distribution and genesis of the anomalously high porosity zones in the middle-shallow horizons of the northern Songliao Basin显示文摘High-quality reservoirs occur in the middle-shallow horizons of the northern Songliao Basin. The distribution and genesis of their anomalously high porosity zones were studied using measured porosities, examination of ordinary thin sections and blue epoxy resin-impregnated thin sections and by SEM. The results show that there are three anomalously high porosity zones at the depth of 450-900 m, 1,300-1,900 m, 2,050-2,350 m respectively, named zone i, zone ii and zone iii from top to bottom. Horizontally, zone i and zone ii are distributed all over the basin except in the Southeastern Uplift, while zone iii is only distributed in the Central Depression. Zone i was formed by meteoric water leaching as well as organic acid dissolution. Zones ii and iii were dominantly formed by organic acid dissolution. Additionally, clay mineral transformation generating H+ and hydrocarbon emplacement retarding the cementation of sandstones are also important for the formation of zones ii and iii. | Meng Yuanlin Liang Hongwei Meng Fanjin Wu Heyong Wang Cheng Xiu Hongwen Zhang Anda Li Yaguang Guo Rixin | 2010 | Petroleum Science2010，7，3： | 29 |
| 9 | Advanced landfill leachate treatment using a two-stage UASB-SBR system at low temperature显示文摘A two-stage upflow anaerobic sludge blanket(UASB) and sequencing batch reactor(SBR) system was introduced to treat landfill leachate for advanced removal of COD and nitrogen at low temperature.In order to improve the total nitrogen(TN) removal efficiency and to reduce the COD requirement for denitrification,the raw leachate with recycled SBR nitrification supernatant was pumped into the first-stage UASB(UASB1) to achieve simultaneous denitrification and methanogenesis.The results showed that UASB1 played an important role in COD removal and UASB2 and SBR further enhanced the nutrient removal efficiency.When the organic loading rates of UASB1,UASB2 and SBR were 11.95,1.63 and 1.29 kg COD/(m3·day),respectively,the total COD removal efficiency of the whole system reached 96.7%.The SBR acted as the real undertaker for NH4+-N removal due to aerobic nitrification.The system obtained about 99.7% of NH4+-N removal efficiency at relatively low temperature(14.9-10.9°C).More than 98.3% TN was removed through complete denitrification in UASB1 and SBR.In addition,temperature had a significant effiect on the rates of nitrification and denitrification rather than the removal of TN and NH4+-N once the complete nitrification and denitrification were achieved. | Hongwei Sun,Qing Yang,Yongzhen Peng,Xiaoning Shi,Shuying Wang,Shujun Zhang Key Laboratory of Beijing Water Quality Science and Water Envirocnnment Recovery Engineering,Beijing University of Technology,Beijing 100124,China | 2010 | Journal of Environmental Sciences2010，22，4： | 26 |
| 10 | Effects of the two-step ageing treatment on the microstructure and properties of 7B04 alloy pre-stretched thick plates显示文摘The effects of the two-step ageing parameters (temperature and time) on the mechanical properties and electrical conductivity of 7B04 (Al-Zn-Mg-Cu) pre-stretched thick plates were studied. The results reveal that the initial T1 ageing contributes a major increase of the tensile strength, and the 0.2% proof stress value reaches 482 MPa after ageing for 7 h at 115°C. Behavioral differences in the tensile properties of the alloy after the two-step ageing treatment were less with the first-step ageing at 115°C for different time periods (7, 14, and 21 h). The effects of the second ageing parameters on the properties and microstructure of the 7B04 alloy were remarkable. TEM analysis of the samples aged at Temper I (7 h at 115°C + 12 h at 160°C) and Temper II (7 h at 115°C + 16 h at 165°C) indicates that two kinds of phases, i.e. η′ and η phases, precipitate from the matrix and efficiently improve the tensile strength of the alloy, and the grain boundary precipitates are coarse and discrete. There are obvious precipitate free zones (PFZs) along the grain boundary in the microstructure of the alloy after the two-step ageing treatment. | LI Zhihui XIONG Baiqing ZHANG Yong 'an ZHU Baohong WANG Feng LIU Hongwei | 2007 | Rare Metals2007，26，3： | 24 |
| 11 | Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system显示文摘MicroRNAs (miRNAs ) 是内长的 noncoding RNA (~ 22 nt ) 在细胞质在 post-transcriptional 水平调整目标基因表示。在房间原子核的要求功能的 argonaute 家庭蛋白质提示了我们假设那 miRNAs 的 miRNAs 和 miRNA 的存在的最近的发现可以也在房间原子核有规章的功能。在这研究,我们证明老鼠 miR-709 主要位于各种各样的房间类型的原子核并且它的原子本地化模式很快在 apoptotic 刺激之上变化。在房间原子核, miR-709 直接在 pri-miR-15a/16-1 上绑在一个 19-nt miR-709 识别元素并且阻止它处理成 pre-miR-15a/16-1,导致 miR-15a/16-1 成熟的抑制。而且,原子 miR-709 通过 miR-15a/16-1 小径参予房间 apoptosis 的规定。在摘要,现在的学习提供一 miRNA 能由直接在原子核指向他们的主要抄本控制另外的 miRNAs 的生物的续生说的第一条证据。 | Rui Tang Limin Li Dihan Zhu Dongxia Hou Ting Cao Hongwei Gu Jing Zhang Junyuan Chen Chen-Yu Zhang Ke Zen | 2012 | Cell Research2012，22，3： | 23 |
| 12 | Trends in cancer mortality in China from 2004 to 2018:A nationwide longitudinal study显示文摘Background:The long-term trend in cancer death in a rapidly developing country provides information for cancer prophylaxis.Here,we aimed to identify the trends in cancer mortality in China during the 2004-2018 period.Methods:Using raw data from the national mortality surveillance system of China,we assessed the mortalities of all cancer and site-specific cancers during the 2004-2018 period.The participants were divided into three age groups:≥65 years,40-64 years,and≤39 years.Changing trends in cancer death by gender,residency,and tumor location were estimated using fitting joinpoint models to log-transformed crude mortality rates(CMRs)and age-standardizedmortality rates(ASMRs).Results:Cancer death accounted for 24% of all-cause of death in China during 2014-2018.The CMR of all cancer was 150.0 per 100,000 persons.Cancer was the leading cause of death in the population<65 years.The six major cancer types(lung/bronchus cancer,liver cancer,stomach cancer,esophagus cancer,colorectal cancer,and pancreas cancer)accounted for 75.85% of all cancer deaths.The CMR of all cancer increased while the ASMR decreased during 2014-2018(P<0.001).Lung/bronchus cancer and liver cancer were the leading causes of cancer death in the population<65 years,accounting for 45.31%(CMR)and 44.35%(ASMR)of all cancer death,respectively.The ASMR of liver cancer was higher in the 40-64 years population than in the≥65 years population,in contrast to the other five major cancers.The ASMRs of liver cancer,stomach cancer,and esophagus cancer decreased although they were higher in rural residents than in urban residents;the ASMRs of lung/bronchus cancer,colorectal cancer,and pancreas cancer increased in rural residents although they were higher in urban residents than in rural residents during 2014-2018.Conclusion:Although the ASMR of all cancer decreased in China during 2004-2018,lung/bronchus cancer and liver cancer remained the leading causes of cancer-related premature death.Lung/bronchus cancer,colorectal cancer,and pancreas cancer increased in rural residents. | Dongming Jiang Lijuan Zhang Wenbin Liu Yibo Ding Jianhua Yin Rongbing Ren Qi Li Yifan Chen Jiaying Shen Xiaojie Tan Hongwei Zhang Guangwen Cao | 2021 | Cancer Communications2021，41，10： | 23 |
| 13 | Protective effect of periplaneta americana extract on intestinal mucosal barrier function in patients with sepsis显示文摘OBJECTIVE: To investigate the effect of the periplaneta americana extract on the intestinal mucosal barrier and prognostic implications in patients with sepsis. METHODS: Sixty and six patients with sepsis were assigned randomly to treatment group (32 cases) and control group (32 cases). The extractfrom periplaneta americana plus conventional medication for sepsis was administered to the treatment group, while the control group only received conventional treatment. The gastrointestinal function scores and acute physiology and chronic health evaluation II (APACHEⅡ) scores of all subjects were documented at baseline, at days 1, 3 and 7 after treatment respectively and their blood endotoxin was tested at the same time points as well.The incidence of death was recorded for both groups throughout the trial. RESULTS: At days 3 and 7 after treatment, gastroin-testinal function score, APACHE II, and endotoxin level in treatment group wasbetter than that in control group and the difference between them was significant (both P<0.05). Although the incidence of death in treatment group was less than that in control group, the difference between the two groups was not significant (P> 0.05). CONCLUSION: The extract of periplaneta americana had protective effect on intestinal mucosal barrier and could improve the condition and prognosis in patients with sepsis. | Hongwei Zhang Liyou Wei Zhenyu Zhang Shuzheng Liu Gang Zhao Jing Zhang Yanling Hu | 2013 | Journal of Traditional Chinese Medicine2013，33，1： | 21 |
| 14 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth显示文摘发信号的调停肽的 cell-to-cell 在植物在细胞的功能的协作和定义有关键角色。肽受体匹配为理解位于调停肽的发信号下面的机制是重要的。这里,我们报导根分裂组织生长的指导结构的鉴定为植物开发重要的因素(RGF ) 受体。基于签名 ligand 识别,主题(Arg-x-Arg ) 在充满白氨酸的重复受体 kinases (LRR-RKs ) 的一个亚科保存了的试金识别了机能上地 uncharacterized LRR-RK At4g26540 作为 RGF1 (RGFR1 ) 的受体。我们进一步在 2.6 Å 的一个决定与 RGFR1 的 LRR 领域在建筑群解决了 RGF1 的水晶结构;,它表明 Arg-x-Gly-Gly (RxGG ) 主题为由 RGFR1 的 RGF1 的硫酸盐组的特定的识别负责。基于 RxGG 主题,我们识别了另外四 RGFR。在导致 RGF 的发信号的五 RGFR 的参予被生物化学、基因的数据支持。我们也提供证明 SERK 为 RGF 作为合作受体工作的证据。一起拿,我们的学习识别 RGF 受体,能连接 RGF 的合作受体与他们的下游的部件发信号并且为与他们的肽 ligands 的 LRR-RKs 的基于结构的匹配提供原则的一个证明。 | Wen Song Li Liu Jizong Wang Zhen Wu Heqiao Zhang Jiao Tang Guangzhong Lin Yichuan Wang Xing Wen Wenyang Li Zhifu Han Hongwei Guo Jijie Chai | 2016 | Cell Research2016，26，6： | 20 |
| 15 | Precise nanomedicine for intelligent therapy of cancer显示文摘Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations. | Huabing Chen Zhanjun Gu Hongwei An Chunying Chen Jie Chen Ran Cui Siqin Chen Weihai Chen Xuesi Chen Xiaoyuan Chen Zhuo Chen Baoquan Ding Qian Dong Qin Fan Ting Fu Dayong Hou Qiao Jiang Hengte Ke Xiqun Jiang Gang Liu Suping Li Tianyu Li Zhuang Liu Guangjun Nie Muhammad Ovais Daiwen Pang Nasha Qiu Youqing Shen Huayu Tian Chao Wang Hao Wang Ziqi Wang Huaping Xu Jiang-Fei Xu Xiangliang Yang Shuang Zhu Xianchuang Zheng Xianzheng Zhang Yanbing Zhao Weihong Tan Xi Zhang Yuliang Zhao | 2018 | Science China Chemistry2018，61，12： | 19 |
| 16 | MiR-29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6显示文摘Osteosarcoma 是骨头的最普通的主要肉瘤,并且它是在青少年和年轻成年人之中的癌症死亡的一个领先的原因。然而,糟糕位于 osteosarcoma carcinogenesis 遗体下面的分子的机制理解。最近, cyclin 依赖的 kinase (CDK6 ) 6 作为重要 oncogene 被识别。我们发现了那 CDK6 蛋白质水平,而非 CDK6 mRNA 水平,比的在 osteosarcoma 纸巾是高得多的在正常邻近的纸巾,它显示在 osteosarcoma 涉及 CDK6 规定的 post-transcriptional 机制。MiRNAs 是镇压的小非编码的 RNA 在 post-transcriptional 水平的基因表示并且广泛地被显示了在许多人的癌症起重要作用。在这研究,我们用生物信息学方法作为 CDK6 的一个新奇管理者调查了 miR-29b 的角色。我们证明 CDK6 能是由经由到在 osteosarcoma 房间的 3-UTR 区域的绑定的 miR-29b 的 downregulated。而且,我们在 osteosarcoma 纸巾识别了在 miR-29b 和 CDK6 蛋白质层次之间的反的关联。最后,我们在 osteosarcoma 房间检验了 CDK6 表示的 miR-29b-driven 压抑的功能。结果表明 miR-29b 由在增长和移植进程指向 CDK6 充当 osteosarcoma 的肿瘤 suppressor。一起拿,我们的结果在 osteosarcoma 在 CDK6 的规定为 miR-29b 加亮一个重要角色并且可以为未来 osteosarcoma 治疗打开新大街。 | Kegan Zhu Lei Liu Junliang Zhang Yanbo Wang Hongwei Liang Gentao Fan Zhenhuan Jiang Chen-Yu Zhang Xi Chen Guangxin Zhou | 2016 | Protein & Cell2016，7，6： | 18 |
| 17 | Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。 | Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang | 2016 | Cell Research2016，26，6： | 17 |
| 18 | Effective gene editing by high-fidelity base editor 2 in mouse zygotes显示文摘通过相应再结合的指向的点 mutagenesis 广泛地在基因研究被使用了并且为在病人修理引起疾病的变化保持可观的诺言。然而,象 mosaicism 那样的问题和低 mutagenesis 效率继续提出挑战到如此的途径的临床的申请。最近,一个基础编辑器() 在 cytidine (C) 脱氨基酶上造的系统和 CRISPR/Cas9 技术在植物,酵母,和人的房间为指向的点 mutagenesis 作为一个其他的方法被开发。然而,基础编辑器高效地在 deamination 窗口中把 C 变换成 thymidine (T) 是否指向了在鼠标胚胎的基础编辑,仍然保持不清楚是可行的。在这份报告,我们产生了基础编辑的一个修改高保真版本 2 (HF2-BE2 ) ,并且调查了它在老鼠胚胎编辑功效的底。我们发现 HF2-BE2 能高效地把 C 变换成 T,与直到在老鼠胚胎的 100% biallelic 变化效率。不同于 BE3, HF2-BE2 能在目标和非目标海滨上把 C 变换成 T,扩展基础编辑器的编辑范围。令人惊讶地,我们发现 HF2-BE2 能也使脱去氨基对 gRNA 有约束力的区域近似的 C。一起拿,我们的工作表明由基础编辑,和下划线在鼠标产生点变化的可行性小心地优化编辑系统以便消除近似地点的 deamination 的底的需要。 | Puping Liang Hongwei Sun Ying Sun Xiya Zhang Xiaowei Xie Jinran Zhang zhen Zhang Yuxi Chen Chenhui Ding Yuanyan Xiong Wenbin Ma Dan Liu Junjiu Huang Zhou Songyang | 2017 | Protein & Cell2017，8，8： | 17 |
| 19 | A novel ionic liquids-based scrubbing process for efficient CO_(2) capture显示文摘A novel alkanolamine-based ionic liquid,N-methyl-diethanolammonium tetrafluoroborate ([MDEA][BF4]),was synthesized in our laboratory.The ionic liquid-based composite solution consisting of N-methyl-diethanolamine (MDEA),[MDEA][BF4],piperazine (PZ) and H2O was investigated for CO_(2) capture.The optimal performance for CO_(2) capture was found at 45°C,1.50 MPa,probably due to a synergistic action of the reaction and the transport.No apparent corrosion was found on stainless and carbon steel with the above composite solution.This finding is very significant to the promotion of its engineering application. | ZHANG SuoJiang ZHANG XiangPing ZHAO YanSong ZHAO GuoYing YAO XiaoQian YAO HongWei | 2010 | Science China Chemistry2010，53，7： | 16 |
| 20 | Simulation of particle flow in a bell-less type charging system of a blast furnace using the discrete element method显示文摘A three-dimensional model was established by the discrete element method(DEM) to analyze the flow and segregation of particles in a charging process in detail.The simulation results of the burden falling trajectory obtained by the model were compared with the industrial charging measurements to validate the applicability of the model.The flow behavior of particles from the weighing hopper to the top layer of a blast furnace and the heaping behavior were analyzed using this model.A radial segregation index(RSI)was used to evaluate the extent of the size segregation in the charging process.In addition,the influence of the chute inclination angle on the size segregation and burden profile during the charging process was investigated. | Jianliang Zhang Jiayong Qiu Hongwei Guo Shan Ren Hui Sun Guangwei Wang Zhengkai Gao | 2014 | Particuology2014，12，5： | 16 |
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