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| 1 | Ecohydrological change mechanism of a rainfed revegetation ecosystem at southeastern edge of Tengger desert,Northwest China显示文摘Study is made on a 45 km-long artificial ecosystem without irrigation in Tengger desert on the basis of long-term ecological monitoring and ecohydrological fundamentals.Changes in water allocation, utilization, cycle and balance patterns in more than 40-year evolution of the soil-plant system are analyzed. The formation of a drought horizon in shrub rhizosphere and its effect, ecohydrological function of the crust and its effect on the soil-plant system change are discussed. Driven by water self-regulation and water stress, the soil-plant system is going to develop towards the steppe desert to ensure more effective use and optimum collocation of water resource. | XIAO Honglang CHENG Guodong LI Xinrong SONG Yaoxuan WANG Xinping | 2004 | Science China Earth Sciences2004，47，z1： | 9 |
| 2 | Development of microsatellite markers and their utilization in genetic diversity analysis of cultivated and wild populations of the mud carp (Cirrhina molitorella)显示文摘Microsatellite markers have been increasingly used in genetic studies on fishery species because of their high applicability in selective breeding programs. Here we reported the development of microsatellite markers and their utilization in mud carp (Cirrhina molitorella). An (CA)15 enriched library has been constructed for mud carp, using the magnetic beads enrichment procedure. Sequence analysis of 60 randomly picked positive colonies indicate that 56 (93.3%) of the colonies contain microsatellites. Microsatellite polymorphism was as-sessed using 10 mud carp individuals, and 12 microsatellite loci turned out to be polymorphic. We utilized these loci to study the genetic diversity of a wild population (WM) and a cultured population (CM) of the mud carp. A total of 109 alleles were detected with an average of 9.08 alleles per locus. The mean value of the observed heterozygosity of WM and CM was 0.6361 and 0.6417, respectively, and sig-nificant decrease of genetic diversity in CM was not observed. The genetic distance between the two populations was 0.1546 and the value of GST was 0.0473. This showed that there existed a slight genetic differentiation between WM and CM. | Cheng Yang Xinping Zhu Xiaowen Sun | 2008 | Journal of Genetics and Genomics2008，35，4： | 9 |
| 3 | Qiguiyishen decoction reduced the accumulation of extracellular matrix in the kidneys of rats with adriamycin-induced nephropathy显示文摘OBJECTIVE: To investigate the effect of Qiguiyishen decoction(QGYS) on the severity of nephropathy.METHODS: Twenty-four rats were randomly divided into four groups(Ⅰ, Ⅱ, Ⅲ, Ⅳ) according to the random number table. Group Ⅰ as control group did not establish nephropathy model. Groups Ⅱ,Ⅲ, and Ⅳ were intravenously administered Adriamycin(7.5 mg/kg) through the tail vein to establish nephropathy model. QGYS was prepared with the extracts of Huangqi(Radix Astragali Mongolici),Danggui(Radix Angelicae Sinensis),Niuxi(RadixAchyran-this Bidentatae), and Chuanxiong(Rhizoma Chuanxiong).Group Ⅳ was administered QGYS (2mL·kg-1·d-1), group Ⅲ was administered benazepril(10 mL·kg-1·d-1), and group Ⅰ, Ⅱ was administered water(2mL·kg-1·d-1)once daily for eight weeks.RESULTS: QGYS reduced the excretion of urinary protein and N-acetyl-β-D-glucosaminidase and alleviated the accumulation of extracellular matrix(ECM) in renal tissue. Additionally, QGYS effectively regulated the levels of transforming growth factor,tissue inhibitor of matrix metalloproteinase, and matrixmetalloprote in asesin the kidney of the rats.CONCLUSION:QGYS may reduce the accumulation of ECM in the kidneys of rats with Adriamycin-induced nephropathy. | Minggang Wei Wei Sun Weiming He Li Ni Xiaofeng Cai Zongqi Cheng Kun Gao Fengling Li Lin Chen Xinping Zhang | 2014 | Journal of Traditional Chinese Medicine2014，34，3： | 4 |
| 4 | First experimental constraints on WIMP couplings in the effective field theory framework from CDEX显示文摘We present weakly interacting massive particles(WIMPs) search results performed using two approaches of effective field theory from the China Dark Matter Experiment(CDEX), based on the data from both CDEX-1B and CDEX-10 stages. In the nonrelativistic effective field theory approach, both time-integrated and annual modulation analyses were used to set new limits for the coupling of WIMP-nucleon effective operators at 90% confidence level(C.L.) and improve over the current bounds in the low mχregion. In the chiral effective field theory approach, data from CDEX-10 were used to set an upper limit on WIMP-pion coupling at 90% C.L. We for the first time extended the limit to the m_(χ)<6 GeV/c^(2) region. | Yi Wang Zhi Zeng Qian Yue LiTao Yang KeJun Kang YuanJing Li Mehment Agartioglu HaiPeng An JianPing Chang JingHan Chen YunHua Chen JianPing Cheng Cheng Yi Chiang WenHan Dai Zhi Deng ChangHao Fang XinPing Geng Hui Gong QiuJu Guo XuYuan Guo HongJian He Li He ShengMing He JinWei Hu TuChen Huang HanXiong Huang HaiTao Jia LiPing Jia Xi Jiang HauBin Li JianMin Li Jin Li MingXuan Li RenMingJie Li Xia Li YuLan Li Bin Liao FongKay Lin ShinTed Lin ShuKui Liu YanDong Liu Yu Liu YuanYuan Liu ZhongZhi Liu Hao Ma YuCai Mao QiYuan Nie JinHua Ning Hui Pan NingChun Qi Jie Ren XiChao Ruan ChangSong Shang Vivek Sharma Ze She Lakhwinder Singh Monoj Kumar Singh TianXi Sun ChangJian Tang WeiYou Tang Yang Tian GuangFu Wang Li Wang Qing Wang Yu Chen Wang YunXiang Wang Zhen Wang Henry Tsz-King Wong ShiYong Wu YuCheng Wu HaoYang Xing Yin Xu Tao Xue YuLu Yan Nan Yi ChunXu Yu HaiJun Yu JianFeng Yue Ming Zeng BingTao Zhang Lei Zhang FengShou Zhang ZhenYu Zhang KangKang Zhao MingGang Zhao JiFang Zhou ZuYing Zhou JingJun Zhu | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，8： | 3 |
| 5 | One-dimensional/three-dimensional analysis of transient cavitating flow in a venturi tube with special emphasis on cavitation excited pressure fluctuation prediction显示文摘The large eddy simulation(LES) method is used to simulate cavitating flow in a venturi tube. The simulated results agree fairly well with the experimental data. To quantitatively describe the relationship between cavitation evolution and excited pressure fluctuation in the venturi tube, a modified prediction model is proposed and its accuracy is verified by the LES results. Based on the original one-dimensional model for the external cavitating flow around a hydrofoil, this model is corrected according to the internal cavitating flow characteristics in the venturi tube. The results show that the original one-dimensional model ignores the choking effect of cavitating flow, which is obvious in a venturi tube with a narrow flow channel, thus leading to an inaccurate prediction of pressure fluctuation in the venturi tube. The modified model can significantly overcome its deficiencies and improve the accuracy of the pressure fluctuation prediction, providing a theoretical basis and guidance for engineering application to controlling the pressure fluctuation in a venturi tube or for other internal flows. | WANG LuYan JI Bin CHENG HuaiYu WANG Jiong LONG XinPing | 2020 | Science China(Technological Sciences)2020，63，2： | 3 |
| 6 | Seawater hydraulics:From the sea surface to depths of 11000 meters显示文摘Using seawater as the working medium,the seawater hydraulic system has significant advantages in the deep sea,such as eliminating contamination caused by oil leaks,no oil tanks,and the ability to automatically adapt to sea depths.As working depths increase,seawater hydraulic technology faces enormous challenges.First,the physical and chemical properties of seawater,such as density,temperature,and composition,change significantly.Second,hydraulic components are subject to an environmental pressure of up to 110 MPa,which causes serious deformation or even seizure of moving pairs and significantly affects the efficiency of hydraulic components.The friction and wear characteristics between the moving pairs also significantly change with the change in sea depth,therefore developing the matching material according to depth is necessary.Finally,the cavitation characteristic of a valve port is obviously different from that on land,so special material and structure should be used to improve the service life of the valve port.These factors severely restrict the improvement of the working depths and characteristics of seawater hydraulic components.This article focuses on the abovementioned problems and provides solutions for deep-sea seawater hydraulic technology. | LIU YinShui CHENG Qian WANG ZhenYao PANG Hao DENG YiPan ZHOU XinPing LUO XiaoHui CUI Yan WU DeFa | 2022 | Science China(Technological Sciences)2022，65，9： | 2 |
| 7 | Active canopy sensor-based precision N management strategy for rice显示文摘 | Yinkun Yao Yuxin Miao Shanyu Huang Lei Gao Xiaobo Ma Guangming Zhao Rongfeng Jiang Xinping Chen Fusuo Zhang Kang Yu Martin Gnyp Georg Bareth Cheng Liu Liqin Zhao Wen Yang Huamin Zhu | 2012 | Agronomy for Sustainable Development2012，，4： | 1 |
| 8 | Effects of Tirofiban on Platelet Activation and Endothelial Function in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention显示文摘 | Kuan Wang Guoxing Zuo Liuying Zheng Cheng Zhang Dong Wang Zhongnan Cao Sheng Hu Xinping Du | 2015 | Cell Biochemistry and Biophysics2015，，1： | 1 |
| 9 | Influence of nozzle exit tip thickness on the performance and flow field of jet pump显示文摘 | LONG Xinping HAN Ning CHENG Qian | | 0，，10： | 1 |
| 10 | Use of digital camera to assess nitrogen status of winter wheat in the northern China plain 显示文摘 | Jia Liangliang Cheng Xinping | 2004 | Journal of Plant Nutrition2004，27，3： | 1 |
| 11 | Use of digital camera to assess nitrogen status of winter wheat in the northern China plain 显示文摘 | Jia Liangliang Cheng Xinping | 2004 | Journal of Plant Nutrition2004，27，3： | 1 |
| 12 | Weekly Assessment of the COVID-19 Pandemic and Risk of Importation--China, March 25, 2020显示文摘Along with the announcement of COVID-19 as a global pandemic by the World Health Organization(WHO)on March 12,2020,COVID-19 appeared to be spreading rapidly around the world.By 10:00 CET on March 25,2020,a total of 331,619 confirmed cases and 15,146 deaths were reported from 195 foreign countries and regions on 6 continents plus the Diamond Princess international cruise ship,and among them,124 countries and regions had local transmission.Cumulatively,the WHO website reported 15,918 confirmed COVID-19 cases from 16 countries and regions in the Western Pacific excluding China,220,516 cases from 60 countries and regions in Europe,2,344 cases from 10 countries and regions in South-East Asia,29,631 cases from 21 countries and regions in the Eastern Mediterranean,60,834 cases from 48 countries and regions in the Americas,and 1,664 cases from 39 countries and regions in Africa(1). | Mingfan Pang Zuoru Liang Zhida Cheng Jun Zhang Nan Huang Li Guo Zengtao Jiao Xinping Yang Yufei Wang Zhongjie Li Yanping Zhang Ke Lyu Wenxiao Tu Xiaopeng Qi Xinhua Li Xiaoping Dong | 2020 | China CDC weekly2020，2，14： | 1 |
| 13 | Chinese registry of rheumatoid arthritis(CREDIT)V:sex impacts rheumatoid arthritis in Chinese patients显示文摘Background: The impact of sex on the clinical manifestations of rheumatoid arthritis (RA) were diversely reported in the literature. The Chinese Registry of rhEumatoiD arthrITis provides a platform for the investigation of this issue in Chinese patients.Methods: Demographic and clinical parameters were collected from all enrolled patients with RA and from patients with early RA (disease duration ≤6 months). The differences in data regarding disease activity, comorbidities, and medications for RA were compared between men and women. The proportions of patients who achieved remission and low disease activity were compared at enrollment and during 3-, 6-, and 12-month follow-up visits.Results: A total of 11,564 patients were enrolled, 83.6% of whom were female. In all the enrolled patients and patients with early RA, C-reactive protein (CRP, 12.0vs. 6.7 mg/L), pain visual analogue scale (4.8vs. 4.5), patient’s and physician’s global assessment (4.9vs. 4.5 and 4.9vs. 4.5), 28-joint disease activity score using DAS28-CRP (4.3vs. 4.0) simplified disease activity index (21.9vs. 19.9), and clinical disease activity index (19.3vs. 18.0) were significantly higher in men than in women. Additionally, the swollen joint count/tender joint count and DAS28 using erythrocyte sedimentation rate were higher in male patients than in female patients with early RA. More female patients with early RA reached the treatment target at baseline than male patients (23.4%vs. 18.2%, assessed by CDAI). At 3 months, 6 months, and 12 months, the proportion of remission and treatment target achievement was similar in both sexes. Coronary artery disease (CAD) and stroke were more frequent in men than in women.Conclusions: In Chinese patients with RA, men were found to have more active disease, as well as more cases of CAD and stroke. Therefore, sex should be carefully considered during the personalization of RA treatment. | Nan Jiang Qin Li Hongbin Li Yongfei Fang Lijun Wu Xinwang Duan Jian Xu Cheng Zhao Zhenyu Jiang Yanhong Wang Qian Wang Xiaomei Leng Mengtao Li Xinping Tian Xiaofeng Zeng CREDIT Co-Authors | 2022 | Chinese Medical Journal2022，135，18： | 1 |
| 14 | Influence of noz- zle exit tip thickness on the performance and flow field of jet pump显示文摘 | Long Xinping Han Ning Cheng Qian | 2008 | Journal of Mechanical Science and Tech- nology2008，22，： | 1 |
| 15 | Anthropogenic monoterpenes aggravating ozone pollution显示文摘Monoterpenes have been known to have a critical influence on air quality and climate change through their impact on the formation of fine particles.Here we present field evidence that monoterpene oxidations largely enhanced local ozone production in a regional site in eastern China.The observed monoterpene was most likely from biomass burning rather than biogenic emissions,as indicated by the high correlation with CO at night-time,and the observed ratio of these two species was consistent with previously determined values from biomass burning experiments.Fast monoterpene oxidations were determined experimentally based on direct radical measurements,leading to a daily ozone enhancement of 4-18 parts per billion by volume(ppb),which was 6%-16%of the total ozone production,depending on the speciation of monoterpenes.It demonstrates that the previously overlo oked anthropogenic monoterpenes make an important contribution to 0_(3) production in eastern China.The role could possibly be important at similar locations across China and other parts of the world that are characterized by massive emissions,especially where there are high NO_(x) levels.Our results highlight that anthropogenic monoterpenes should be taken into account when proceeding with the coordinated mitigation of O_(3) and particulate matter pollution. | Haichao Wang Xuefei Ma Zhaofeng Tan Hongli Wang Xiaorui Chen Shiyi Chen Yaqin Gao Ying Liu Yuhan Liu Xinping Yang Bin Yuan Limin Zeng Cheng Huang Keding Lu Yuanhang Zhang | 2022 | National Science Review2022，9，9： | 1 |
| 16 | Use of digital camera to assess nitrogen status of winter wheat in the northern China plain 显示文摘 | Jia Liangliang Cheng Xinping | 2004 | Journal of Plant Nutrition2004，27，3： | 1 |
| 17 | Reciprocal costimulatory molecules control the activation of mucosal type 3 innate lymphoid cells during engagement with B cells显示文摘Innate lymphoid cells(ILCs)are the counterpart of T helper cells in the innate immune system and share multiple phenotypes with T helper cells.Inducible T-cell costimulator(ICOS)is recognized on T cells and participates in T-cell activation and T and B-cell engagement in lymphoid tissues.However,the role of ICOS in ILC3s and ILC3-involved interactions with the immune microenvironment remains unclear.Here,we found that ICOS expression on human ILC3s was correlated with the activated state of ILC3s.ICOS costimulation enhanced the survival,proliferation,and capacity of ILC3s to produce cytokines(IL-22,IL-17A,IFN-γ,TNF,and GM-CSF).Via synergistic effects of ICOS and CD40 signaling,B cells promoted ILC3 functions,and ILC3-induced T-cellindependent B-cell IgA and IgM secretion primarily required CD40 signaling.Hence,ICOS is essential for the nonredundant role of ILC3s and their interaction with adjacent B cells. | Xinping Lv Shan Zhu Jing Wu Jinfeng Shi Qiuyu Wei Tete Li Ning Yang Chunyan Liu Lingli Qi Guoxia Zang Hang Cheng Zhiguang Yang Chengyan Jin Yusheng Wang Jiuwei Cui Hideki Ueno Yong-Jun Liu Jingtao Chen | 2023 | Cellular & Molecular Immunology2023，20，7： | 0 |
| 18 | A critical review on composite solid electrolytes for lithium batteries:Design strategies and interface engineering显示文摘The rapid development of new energy vehicles and 5G communication technologies has led to higher demands for the safety,energy density,and cycle performance of lithium-ion batteries as power sources.However,the currently used liquid carbonate compounds in commercial lithium-ion battery electrolytes pose potential safety hazards such as leakage,swelling,corrosion,and flammability.Solid electrolytes can be used to mitigate these risks and create a safer lithium battery.Furthermore,high-energy density can be achieved by using solid electrolytes along with high-voltage cathode and metal lithium anode.Two types of solid electrolytes are generally used:inorganic solid electrolytes and polymer solid electrolytes.Inorganic solid electrolytes have high ionic conductivity,electrochemical stability window,and mechanical strength,but suffer from large solid/solid contact resistance between the electrode and electrolyte.Polymer solid electrolytes have good flexibility,processability,and contact interface properties,but low room temperature ionic conductivity,necessitating operation at elevated temperatures.Composite solid electrolytes(CSEs) are a promising alternative because they offer light weight and flexibility,like polymers,as well as the strength and stability of inorganic electrolytes.This paper presents a comprehensive review of recent advances in CSEs to help researchers optimize CSE composition and interactions for practical applications.It covers the development history of solid-state electrolytes,CSE properties with respect to nanofillers,morphology,and polymer types,and also discusses the lithium-ion transport mechanism of the composite electrolyte,and the methods of engineering interfaces with the positive and negative electrodes.Overall,the paper aims to provide an outlook on the potential applications of CSEs in solid-state lithium batteries,and to inspire further research aimed at the development of more systematic optimization strategies for CSEs. | Tianqi Yang Cheng Wang Wenkui Zhang Yang Xia Hui Huang Yongping Gan Xinping He Xinhui Xia Xinyong Tao Jun Zhang | 2023 | Journal of Energy Chemistry2023，，9： | 0 |
| 19 | Aberrant expression of the extracellular matrix component Biglycan regulated by Hedgehog signalling promotes colorectal cancer cell proliferation显示文摘Hedgehog(Hh)signalling plays essential roles in regulating embryonic development and contributes to tumour initiation,growth and progression in multiple cancers.The detailed mechanism by which Hh signalling participates in tumour growth warrants thorough study,although several downstream target genes have been identified.Herein,a set of novel targets of Hh signalling was identified in multiple types of tumour cells via RNA-Seq analysis.Among these targets,the expression regulation and oncogenic function of the extracellular matrix component biglycan(BGN)were investigated.Further investigation verified that Hh signalling activates the expression of BGN via the transcription factor Gli2,which directly binds to the promoter region of BGN.Functional assays revealed that BGN facilitates tumour cell growth and proliferation in colorectal cancer(CRC)cells,and xenograft assays confirmed that BGN also promotes tumour growth in vivo.Moreover,analysis of clinical CRC samples showed that both the protein and mRNA levels of BGN are increased in CRC tissues compared to those in adjacent tissues,and higher expression of BGN is correlated with poorer prognosis of CRC patients,further confirming the function of BGN in CRC.Taken together,aberrantly activated Hh signalling increases the expression of BGN,possibly regulates the extracellular matrix,and thereby promotes tumour growth in CRC. | Shaopeng Zeng Feifei Zhou Yiqing Wang Zhenyu Zhai Linlin Xu Hailong Wang Xinping Chen Shiwen Luo Minzhang Cheng | 2022 | Acta Biochimica et Biophysica Sinica2022，54，2： | 0 |
| 20 | DNA methylation markers in the diagnosis and prognosis of common leukemias显示文摘The ability to identify a specific type of leukemia using minimally invasive biopsies holds great promise to improve the diagnosis,treatment selection,and prognosis prediction of patients.Using genome-wide methylation profiling and machine learning methods,we investigated the utility of CpG methylation status to differentiate blood from patients with acute lymphocytic leukemia(ALL)or acute myelogenous leukemia(AML)from normal blood.We established a CpG methylation panel that can distinguish ALL and AML blood from normal blood as well as ALL blood from AML blood with high sensitivity and specificity.We then developed a methylation-based survival classifier with 23 CpGs for ALL and 20 CpGs for AML that could successfully divide patients into high-risk and low-risk groups,with significant differences in clinical outcome in each leukemia type.Together,these findings demonstrate that methylation profiles can be highly sensitive and specific in the accurate diagnosis of ALL and AML,with implications for the prediction of prognosis and treatment selection. | Hua Jiang Zhiying Ou Yingyi He Meixing Yu Shaoqing Wu Gen Li Jie Zhu Ru Zhang Jiayi Wang Lianghong Zheng Xiaohong Zhang Wenge Hao Liya He Xiaoqiong Gu Qingli Quan Edward Zhang Huiyan Luo Wei Wei Zhihuan Li Guangxi Zang Charlotte Zhang Tina Poon Daniel Zhang Ian Ziyar Run-ze Zhang Oulan Li Linhai Cheng Taylor Shimizu Xinping Cui Jian-kang Zhu Xin Sun Kang Zhang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
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