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| 1 | Rainfall interception by sand-stabilizing shrubs related to crown structure显示文摘On the edge of the Tengger Desert in northern China,revegetation has changed the landscape from moving dunes to stabilized dunes covered by shrubs,which further modifies the pattern of rainfall redistribution.To study rainfall interception loss by shrubs and its relationship to rainfall properties and crown structure,throughfalls passing through crowns of Artemisia ordosica Krash.and Caragana korshinskii Kom.were measured using nine PVC cups under the canopy of each of the two shrubs during 73 rain events over a three-year period,with total rainfall of 260.9 mm.Interception losses of gross rainfall by A.ordosica and C.korshinskii account for 15% and 27% of the total on a crown area basis,and 6% and 11% on a ground area basis,respectively.Individual throughfall(T) and interception(I) were significantly related to rainfall amount(Pg),duration(D),and intensity(R).Ratios of throughfall to rainfall(T/Pg) and interception to rainfall(I/Pg) were not only significantly related to Pg,D,and R,but also to shrub species,and interactions of species with crown volume(CV) and leaf area index(LAI).Under most rain events,interceptions by C.korshinskii with greater CV and LAI were significantly higher than those by A.ordosica,and more rainfall interception occurred at locations closer to the stems of the two shrubs.For C.korshinskii,I/Pg had a significant positive linear relation with CV and LAI,while T/Pg had a significant negative linear relation with them.CV has a greater influence on T/Pg and I/Pg than does LAI.Using a regression method,canopy water storage capacities are estimated to be 0.52 and 0.68 mm,and free throughfall coefficient to be 0.62 and 0.47 for A.ordosica and C.korshinskii,respectively. | ZhiShan Zhang 1*,XinRong Li 1,XueJun Dong 2,XiaoHong Jia 1,MingZhu He 1,HuiJuan Tan 1 1.Shapotou Desert Research and Experiment Station,Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou,Gansu 730000,China.2.Central Grasslands Research Extension Center,North Dakota State University,Streeter,ND 58483,USA. | 2009 | Research in Cold and Arid Regions2009，1，2： | 9 |
| 2 | Effects of the radial force on the static contact properties and sealing performance of a radial lip seal显示文摘The radial force is a critical factor to determine the sealing performance of radial lip seals.The effects of radial force produced by garter spring and interference on the static contact properties and sealing performance of a radial lip seal are investigated by numerical simulations and experiments.Finite-element analysis and mixed elastohydrodynamic lubrication simulation are used.Radial force,contact width,temperature in the sealing zone,the reverse pumping rate and friction torque are measured.A critical value of interference for a cost-effectively designed radial lip seal is found.Spring force is required to compensate the decrease of the radial force because of the interference and used as a possible way to obtain intelligent control of sealing performance.The quantitative results gotten in this study could provide guide for the seal design and improvement. | JIA XiaoHong GUO Fei HUANG Le WANG LongKe GAO Zhi WANG YuMing | 2014 | Science China(Technological Sciences)2014，57，6： | 8 |
| 3 | Novel backstepping design for blended aero and reaction-jet missile autopilot显示文摘The advanced missile uses blended control of aero-fin and reaction-jet to improve missile maneuver-ability. The blended control design, which is multi-inputs and multi-outputs (MIMO), severe nonlinear, and model uncertain, is much more complex than conventional aero-fin control. A novel nonlinear backstepping control ap-proach is proposed to design the blended autopilot. Missile model is reformed to a new one by state reconstruction technique so that it is easy to be handled by the backstepping method. Then a Lyapunov function is chosen to avoid oscillation caused in normal backstepping way when control parameters are mismatched. In distribution of both inputs, optimal energy logic is proposed. In addition, a fuzzy cerebellar model articulation controller (FCMAC) neural network is used to guarantee controller robustness to uncertainties. Finally, simulation results demonstrate the eficiency and advantages of the proposed method. | Liu Zhong Jia Xiaohong | 2008 | Journal of Systems Engineering and Electronics2008，19，1： | 7 |
| 4 | Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination显示文摘 | Xiaofeng Liang Shengli Bi Weizhong Yang Longde Wang Gang Cui Fuqiang Cui Yong Zhang Jianhua Liu Xiaohong Gong Yuansheng Chen Fuzhen Wang Hui Zheng Feng Wang Jing Guo Zhiyuan Jia Jingchen Ma Huaqing Wang Huiming Luo Li Li Shuigao Jin Stephen C. Hadler Yu W | 2009 | Vaccine2009，，47： | 7 |
| 5 | Cyber-physical model for efficient and secured operation of CPES or energy Internet显示文摘Dear editor, Global energy and environmental crisis is one of the most serious issues on the sustainable develop- ment of human society in the 21st century.Making full use of renewable energy sources is one of the most effective ways to resolve the energy and en- vironmental problems.However,we are facing the serious challenges due to the uncertain natures of the renewable energy sources. | Xiaohong GUAN Zhanbo XU Qing-Shan JIA Kun LIU Yadong ZHOU | 2018 | Science China(Information Sciences)2018，61，11： | 6 |
| 6 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 7 | The effect of texture on the shaft surface on the sealing performance of radial lip seals显示文摘On the basis of elastohydrodynamic model,the present study numerically analyzes the effect of various microdimple texture shapes,namely,circular,square,oriented isosceles triangular,on the pumping rate and the friction torque of radial lip seals,and determines the microdimple texture shape that can produce positive pumping rate.The area ratio,depth and shape dimension of a single texture are the most important geometric parameters which influence the tribological performance.According to the selected texture shape,parameter analysis is conducted to determine the optimal combination for the above three parameters.Simultaneously,the simulated performances of radial lip seal with texture on the shaft surface are compared with those of the conventional lip seal without any texture on the shaft surface. | GUO Fei JIA XiaoHong GAO Zhi WANG YuMing | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，7： | 5 |
| 8 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 9 | Gut Microbiota Dysbiosis Strengthens Kupffer Cell-mediated Hepatitis B Virus Persistence through Inducing Endotoxemia in Mice显示文摘Background and Aims:Change of gut microbiota com-position is associated with the outcome of hepatitis B virus(HBV)infection,yet the related mechanisms are not fully characterized.The objective of this study was to investigate the immune mechanism associated with HBV persistence induced by gut microbiota dysbiosis.Methods:C57BL/6 mice were sterilized for gut-microbiota by using an antibi-otic(ABX)mixture protocol,and were monitored for their serum endotoxin(lipopolysaccharide[LPS])levels.An HBV-replicating mouse model was established by performing HBV-expressing plasmid pAAV/HBV1.2 hydrodynamic injec-tion(HDI)with or without LPS,and was monitored for se-rum hepatitis B surface antigen,hepatitis B e antigen,HBV DNA,and cytokine levels.Kupffer cells(KCs)were purified from antibiotic-treated mice and HBV-replicating mice and analyzed for IL-10 production and T cell suppression ability.Results:ABX treatment resulted in increased serum LPS levels in mice.The KCs separated from both ABX-treated and LPS-treated HBV-replicating mice showed significantly increased IL-10 production and enhanced ability to suppress IFN-γproduction of TCR-activated T cells than the KCs sep-arated from their counterpart controls.HDI of pAAV/HBV1.2 in combination with LPS in mice led to a delayed HBV clear-ance and early elevation of serum IL-10 levels compared to pAAV/HBV1.2 HDI alone.Moreover,IL-10 function blockade or KC depletion led to accelerated HBV clearance in LPS-treated HBV-replicating mice.Conclusions:Our results suggest that dysbiosis of the gut microbiota in mice leads to endotoxemia,which induces KC IL-10 production and strengthens KC-mediated T cell suppression,and thus fa-cilitates HBV persistence. | Wenqing Zhou Jinzhuo Luo Xiaohong Xie Shangqing Yang Dan Zhu Hongming Huang Dongliang Yang Jia Liu | 2022 | Journal of Clinical and Translational Hepatology2022，10，1： | 4 |
| 10 | Electrolyte for lithium protection: From liquid to solid显示文摘Lithium battery with high energy density and enhanced safety is undoubtedly the ideal choice for consumer electronics and electric vehicles.Metal anode such as lithium has been considered as the most effective way to enhance the energy density as it provides ultra-high theoretical capacity and the lowest redox potential.However,due to the low coulombic efficiency as well as safety concerns originated from dendrite issue of lithium,its further commercial utilization is hindered.Dendrite growth is a common phenomenon in metal electrodeposition while the plating process of Li is more complicated than other metals for its high reactivity nature.As a matter of fact,the Li plating process is accompanied with the generation of solid electrolyte interphase(SEI)in which the electrolyte plays a vital role.In this paper,recent advances of electrolytes for Li protect application are reviewed,from liquid to gel polymer and solid state,on which we find that although tremendous progress has been accomplished,there are still great challenges before Li metal anode could be commercially used. | Xiaohong Wu Kecheng Pan Mengmin Jia Yufei Ren Hongyan He Lan Zhang Suojiang Zhang | 2019 | Green Energy & Environment2019，4，4： | 4 |
| 11 | Toward a high resolution 2-DE profile of the normal human liver proteome using ultra-zoom gels显示文摘The human liver is the largest organ in the body and has many important physiological functions. A global analysis of human liver proteins is essential for a better understanding of the molecular basis of the normal functions of the liver and of its diseases. As part of the Human Liver Proteome Project (HLPP), the goal of the present study was to visualize and detect as many proteins as possible in normal human livers using two-dimensional gel electrophoresis (2-DE). We have constructed a reference map of the proteins of human normal liver that can be used for the comprehensive analysis of the human liver proteome and other related research. To improve the resolution and enhance the detection of low abundance proteins, we developed and optimized narrow pH range ultra-zoom 2-DE gels. High resolution patterns of human liver in pH gradients 4.5-5.5, 5-6, 5.5-6.7, 6-9 and 6-11 are presented. To improve the poor resolution in the alkaline pH range of 2-DE gels, we optimized the isoelectric focusing protocol by including sample application using cup loading at the anode and incorporating 1.2% hydroxyethyl disulfide, 15% 2-propanol and 5% glycerol in the rehydration buffer. Using the optimized protocol, we obtained reproducibly better resolution in both analytical and preparative 2-DE gels. Compared with the 2386 and 1878 protein spots resolved in the wide range 3-10 and 4-7 pH gradients respectively, we obtained 5481 protein spots from the multiple (overlapping) narrow pH range ultra-zoom gels in the range of pH 4.5-9. The visualized reference map of normal human liver proteins presented in this paper will be valuable for comparative proteomic research of the liver proteome. | MI Wei LIU Xin JIA Wei LI Lei CAI Yun YING WanTao QIAN XiaoHong | 2011 | Science China(Life Sciences)2011，54，1： | 4 |
| 12 | Rational synthetic combination genetic devices boosting high temperature ethanol fermentation显示文摘The growth and production of yeast in the industrial fermentation are seriously restrained by heat stress and exacerbated by heat induced oxidative stress.In this study,a novel synthetic biology approach was developed to globally boost the viability and production ability of S.cerevisiae at high temperature through rationally designing and combing heat shock protein(HSP)and superoxide dismutase(SOD)genetic devices to ultimately synergistically alleviate both heat stress and oxidative stress.HSP and SOD from extremophiles were constructed to be different genetic devices and they were preliminary screened by heat resistant experiments and anti-oxidative experiments,respectively.Then in order to customize and further improve thermotolerance of S.cerevisiae,the HSP genetic device and SOD genetic device were rationally combined.The results show the simply assemble of the same function genetic devices to solve heat stress or oxidative stress could not enhance the thermotolerance considerably.Only S.cerevisiae with the combination genetic device(FBA1p-sod-MB4-FBA1p-shsp-HB8)solving both stress showed 250%better thermotolerance than the control and displayed further 55%enhanced cell density compared with the strains with single FBA1p-sod-MB4 or FBA1p-shsp-HB8 at 42C.Then the most excellent combination genetic device was introduced into lab S.cerevisiae and industrial S.cerevisiae for ethanol fermentation.The ethanol yields of the two strains were increased by 20.6%and 26.3%compared with the control under high temperature,respectively.These results indicate synergistically defensing both heat stress and oxidative stress is absolutely necessary to enhance the thermotolerance and production of S.cerevisiae. | Huan Sun Haiyang Jia Jun Li Xudong Feng Yueqin Liu Xiaohong Zhou Chun Li | 2017 | Synthetic and Systems Biotechnology2017，2，2： | 3 |
| 13 | An Assessment of Androgenic/Anti-androgenic Effects of GH Transgenic Carp by Hershberger Assay显示文摘Objective To evaluate the androgenic and anti-androgenic effects of GH (growth hormone) transgenic carp in male rats.Methods Hershberger assay was carried out in castrated male SD rats aged 4-5 weeks.Testosterone propionate (TP) (0.4 mg/kg BW) was administrated for a positive control,GH transgenic carp (3.0 g/kg BW)+TP (0.4 mg/kg BW),parental carp (3.0 g/kg BW) + TP (0.4 mg/kg BW),and flutamide (Flu) (3.0 g/kg BW) were used for negative controls,and vehicle was administered orally for a blank control.All groups were administrated for 10 consecutive days.At the end of the test,animals were anesthetized,then weights of accessory sex organ were measured.Serum testosterone (T),luteinizing hormone (LH),and Follicle-Stimulating Hormone (FSH) levels were detected.Results The weights ratios of the accessory sex organs and body weights showed no significant differences between the solvent control and the GH transgenic carp-treated groups.Serum concentrations of FSH,LH,and T of the rats treated with GH transgenic carp + TP showed no significant changes,compared with those treated with TP only.Conclusion GH transgenic carp does not have any androgenic agonist or antagonist properties in vivo screening tests. | LIU YuMei ZHANG WenZhong YONG Ling ZHAO XiaoHong JIA XuDong LI Ning | 2011 | Biomedical and Environmental Sciences2011，24，4： | 3 |
| 14 | External-force-driven solution epitaxy of large-area 2D organic single crystals for high-performance field-effect transistors显示文摘Growth of two-dimensional(2D)organic single crystals(2DOSCs)on water surface has attracted increasing attention,because it can serve as a molecularly flat and defect-free substrate.However,large-area growth of 2DOSCs with controllable crystal orientation on water surface remains a key challenge.Herein,we develop a simple method,i.e.external-force-driven solution epitaxy(EFDSE),for the large-area growth of 2DOSCs at air/water interface.Using 2,7-didecylbenzothienobenzothiophene(C1o-BTBT)as an example,high-quality 2D C10-BTBT crystals on centimeter scale are generated by directionally controlling the spreading of organic solution on water surface with external force.Benefiting from the controllable crystal orientation with optimal charge transport,the corresponding 2DOSC-based organic field-effect transistors(OFETs)exhibit a high carrier mobility of 13.5 cm^2·V^-1·s^-1(effective mobility=5.4 cm^2·V^-1·s^-1 according to a reliability factor of 40%),which represents the best result achieved for water-surface-assembled 2DOSC based OFETs.Furthermore,by transterring the C1o-BTBT 2DOSCs to flexible substrates,devices with excellent bending stability are achieved.It is anticipated that our method will provide new insight into the controllable growth of large-area 2DOSCs for high-performance organic devices. | Jinwen Wang Wei Deng Wei Wang Ruofei Jia Xiuzhen Xu Yanling Xiao Xiujuan Zhang Jiansheng Jie Xiaohong Zhang | 2019 | Nano Research2019，12，11： | 3 |
| 15 | Tool Orientation Optimization and Path Planning for 5-Axis Machining显示文摘Tool path generation is a fundamental problem in 5-axis CNC machining, which consists of tool orientation planning and cutter-contact(CC) point planning. The planning strategy highly depends on the type of tool cutters. For ball-end cutters, the tool orientation and CC point location can be planned separately;while for flat end cutters, the two are highly dependent on each other. This paper generates a smooth tool path of workpiece surfaces for flat end mills from two stages: Computing smooth tool orientations on the surface without gouging and collisions and then designing the CC point path. By solving the tool posture optimization problem the authors achieve both the path smoothness and the machining efficiency. Experimental results are provided to show the effectiveness of the method. | YUAN Chunming MI Zhenpeng JIA Xiaohong LIN Fengming SHEN Liyong | 2021 | Journal of Systems Science & Complexity2021，34，1： | 3 |
| 16 | On large action space in EV charging scheduling optimization显示文摘In order to reduce the air pollution by traditional fossil fuel and save the charging cost, much attention has been paid to the charging scheduling of electric vehicles(EVs) in the uncertain supplement of wind power and solar power. Owing to the randomness in the renewable power generation and the EV charging demand, simulation-based policy improvement(SBPI) has been well adopted for making charging decision. However, it is challenging to explore the large action space which grows exponentially with respect to the system scale. We consider this important problem in this paper and make the following contributions.First, we explore the structural property of the problem and develop an urgency index to rank the EVs.Second, we apply three methods to search in the action space. Third, we numerically demonstrate the performance of the urgency index and the search methods, and compare the SBPI methods with the CPLEXbased method. It shows that SBPI improves the base policies in all these cases. | Zhaoyu JIANG Qing-Shan JIA Xiaohong GUAN | 2022 | Science China(Information Sciences)2022，65，2： | 2 |
| 17 | Changes in compressed neurons from dogs with acute and severe cauda equina constrictions following intrathecal injection of brain-derived neurotrophic factor-conjugated polymer nanoparticles显示文摘This study established a dog model of acute multiple cauda equina constriction by experimental constriction injury (48 hours) of the lumbosacral central processes in dorsal root ganglia neurons. The repair effect of intrathecal injection of brain-derived neurotrophic factor with 15 mg encapsulated biodegradable poly(lactide-co-glycolide) nanoparticles on this injury was then analyzed. Dorsal root ganglion cells (L7) of all experimental dogs were analyzed using hematoxylin-eosin staining and immunohistochemistry at 1, 2 and 4 weeks following model induction. Intrathecal injection of brain-derived neurotrophic factor can relieve degeneration and inflammation, and elevate the expression of brain-derived neurotrophic factor in sensory neurons of compressed dorsal root ganglion. Simultaneously, intrathecal injection of brain-derived neurotrophic factor obviously improved neurological function in the dog model of acute multiple cauda equina constriction. Results verified that sustained intraspinal delivery of brain-derived neurotrophic factor encapsulated in biodegradable nanoparticles promoted the repair of histomorphology and function of neurons within the dorsal root ganglia in dogs with acute and severe cauda equina syndrome. | Junming Tan Jiangang Shi Guodong Shi Yanling Liu Xiaohong Liu Chaoyang Wang Dechun Chen Shunming Xing Lianbing Shen Lianshun Jia Xiaojian Ye Hailong He Jiashun Li | 2013 | Neural Regeneration Research2013，8，3： | 2 |
| 18 | Effects of wind guide plates on wind velocity acceleration and dune leveling: a case study in Ulan Buh Desert, China显示文摘The areas used to be covered by shifting sand dunes have been reclaimed rapidly in recent years. However, it is a challenge to reclaim high sand dunes because it is rather costly to level the high dunes to gentle arable lands. In this study, a wind guide plate was used to change the characteristics of natural wind to level the sand dunes. The use of wind energy could significantly increase the efficiency of dune leveling and decrease the cost. Low wind velocity is a typical characteristic in Ulan Buh Desert of China where the average wind speed is much lower than the threshold velocity for sand movement. The experiment of this study was conducted to accelerate the wind velocity by a wind guide plate to level a sand dune. Results show that the threshold velocity for sand movement is 3.32 m/s at 10 cm above the sand surface in Ulan Buh Desert. A wind guide plate set at an angle less than 50° could significantly increase the wind velocity. The wind velocity could be accelerated up to the threshold velocity for sand movement behind a plate when the plate is at the angles of 20°, 25°, 35° and 40°. The most significant acceleration of wind velocity appears at 1.5 and 3.0 m behind the plate with an angle of 25°. An obvious wind velocity acceleration zone exists behind the wind guide plate when the angles are at 25°, 35°, 40° and 45°, with the most obvious zone under the angle of 45°. The results also show that the total amount of sand transferred over the experimental period increased by 6.1% under the effects of wind guide plates compared to the sand moved without wind guide plates. The results of the study will provide theoretical and practical supports for desert management in sand dune areas. | HAN Yanlong GAO Yong MENG Zhongju DANG Xiaohong JIA Xu DING Yanlong LI Peng | 2017 | Journal of Arid Land2017，9，5： | 2 |
| 19 | Seasonal variation in soil microbial biomass carbon and nitrogen in an artificial sand-binding vegetation area in Shapotou, northern China显示文摘In this study,seasonal variation characteristics of surface soil microbial biomass carbon(MBC)and soil microbial biomass nitrogen(MBN)of an artificial vegetation area located in Shapotou for different time periods were studied using the chloroform fumigation method,and the results were compared with those of near-natural vegetation areas and mobile dunes.Results showed that the MBC and MBN levels in the 0–5 cm soil layer were higher in autumn than in summer and spring.As the prolongation of vegetation restoration raised the MBC and MBN levels in summer and autumn,no clear variation was found in spring.However,the MBC and MBN in 5–20 cm had no obvious seasonal variation.During summer and autumn,the variation trend of MBC and MBN in the vertical direction was shown to be0–5>5–10>10–20 cm in the vegetation area,while for mobile dunes,the MBC and MBN levels increased as the depth increased.The natural vegetation area was shown to possess the highest MBC and MBN levels,and yet mobile dunes have the lowest MBC and MBN levels.MBC and MBN levels in artificial sand-binding vegetation increased with the prolongation of vegetation restoration,indicating that the succession of sand-binding vegetation will result in the accumulation of soil carbon and nitrogen,as well as the restoration of soil fertility. | YuYan Zhou XuanMing Zhang XiaoHong Jia JinQin Ma YanHong Gao | 2013 | Research in Cold and Arid Regions2013，5，6： | 2 |
| 20 | New insights for infection mechanism and potential targets of COVID-19:Three Chinese patent medicines and three Chinese medicine formulas as promising therapeutic approaches显示文摘The coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)with high pathogenicity and infectiousness has become a sudden and lethal pandemic worldwide.Currently,there is no accepted specific drug for COVID-19 treatment.Therefore,it is extremely urgent to clarify the pathogenic mechanism and develop effective therapies for patients with COVID-19.According to several reliable reports from China,traditional Chinese medicine(TCM),especially for three Chinese patent medicines and three Chinese medicine formulas,has been demonstrated to effectively alleviate the symptoms of COVID-19 either used alone or in combination with Western medicines.In this review,we systematically summarized and analyzed the pathogenesis of COVID-19,the detailed clinical practice,active ingredients investigation,network pharmacology prediction and underlying mechanism verification of three Chinese patent medicines and three Chinese medicine formulas in the COVID-19 combat.Additionally,we summarized some promising and high-frequency drugs of these prescriptions and discussed their regulatory mechanism,which provides guidance for the development of new drugs against COVID-19.Collectively,by addressing critical challenges,for example,unclear targets and complicated active ingredients of these medicines and formulas,we believe that TCM will represent promising and efficient strategies for curing COVID-19 and related pandemics. | Kexin Jia Yijie Li Tiegang Liu Xiaohong Gu Xiaojiaoyang Li | 2023 | Chinese Herbal Medicines2023，15，2： | 2 |
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