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    题名 作者 年代 出处 被引量
1TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu 2012Cell Research2012,22,3:18
2The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment.ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart 2019Science China(Physics,Mechanics & Astronomy)2019,62,2:11
3A NAC transcription factor, NOR-like1, is a new positive regulator of tomato fruit ripening显示文摘Ripening of the model fruit tomato(Solanum lycopersicum)is controlled by a transcription factor network including NAC(NAM,ATAF1/2,and CUC2)domain proteins such as No-ripening(NOR),SlNAC1,and SlNAC4,but very little is known about the NAC targets or how they regulate ripening.Here,we conducted a systematic search of fruit-expressed NAC genes and showed that silencing NOR-like1(Solyc07g063420)using virus-induced gene silencing(VIGS)inhibited specific aspects of ripening.Ripening initiation was delayed by 14 days when NOR-like1 function was inactivated by CRISPR/Cas9 and fruits showed obviously reduced ethylene production,retarded softening and chlorophyll loss,and reduced lycopene accumulation.RNA-sequencing profiling and gene promoter analysis suggested that genes involved in ethylene biosynthesis(SlACS2,SlACS4),color formation(SlGgpps2,SlSGR1),and cell wall metabolism(SlPG2a,SlPL,SlCEL2,and SlEXP1)are direct targets of NOR-like1.Electrophoretic mobility shift assays(EMSA),chromatin immunoprecipitation-quantitative PCR(ChIP-qPCR),and dual-luciferase reporter assay(DLR)confirmed that NOR-like1 bound to the promoters of these genes both in vitro and in vivo,and activated their expression.Our findings demonstrate that NOR-like1 is a new positive regulator of tomato fruit ripening,with an important role in the transcriptional regulatory network.Ying Gao Wei Wei Xiaodan Zhao Xiaoli Tan Zhongqi Fan Yiping Zhang Yuan Jing Lanhuan Meng Benzhong Zhu Hongliang Zhu Jianye Chen Cai-Zhong Jiang Donald Grierson Yunbo Luo Da-Qi Fu 2018Horticulture Research2018,5,1:9
4An individualized immune signature of pretreatment biopsies predicts pathological complete response to neoadjuvant chemoradiotherapy and outcomes in patients with esophageal squamous cell carcinoma显示文摘No clinically available biomarkers can predict pathological complete response(pCR)for esophageal squamous cell carcinomas(ESCCs)with neoadjuvant chemoradiotherapy(nCRT).Considering that antitumor immunity status is an important determinant for nCRT,we performed an integrative analysis of immune-related gene profiles from pretreatment biopsies and constructed the first individualized immune signature for pCR and outcome prediction of ESCCs through a multicenter analysis.During the discovery phase,14 differentially expressed immune-related genes(DEIGs)with greater than a twofold change between pCRs and less than pCRs(Chaoqi Zhang Guochao Zhang Nan Sun Zhen Zhang Liyan Xue Zhihui Zhang Haijun Yang Yuejun Luo Xiaoli Zheng Yonglei Zhang Yufen Yuan Ruixue Lei Zhaoyang Yang Bo Zheng Le Wang Yun Che Feng Wang Sihui Wang Shugeng Gao Qi Xue Yi Zhang Jie He 2020Signal Transduction and Targeted Therapy2020,5,1:7
5Evolution of permafrost in China during the last 20 ka显示文摘The formation and evolution of permafrost in China during the last 20 ka were reconstructed on the basis of large amount of paleo-permafrost remains and paleo-periglacial evidence, as well as paleo-glacial landforms, paleo-flora and paleofauna records. The results indicate that, during the local Last Glacial Maximum(LLGM) or local Last Permafrost Maximum(LLPMax), the extent of permafrost of China reached 5.3×106-5.4×106 km2, or thrice that of today, but permafrost shrank to only0.80×106-0.85×106 km2, or 50% that of present, during the local Holocene Megathermal Period(LHMP), or the local Last Permafrost Minimum(LLPMin). On the basis of the dating of periglacial remains and their distributive features, the extent of permafrost in China was delineated for the two periods of LLGM(LLPMax) and LHMP(LLPMin), and the evolution of permafrost in China was divided into seven periods as follows:(1) LLGM in Late Pleistocene(ca. 20000 to 13000-10800 a BP)with extensive evidence for the presence of intensive ice-wedge expansion for outlining its LLPMax extent;(2) A period of dramatically changing climate during the early Holocene(10800 to 8500-7000 a BP) when permafrost remained relatively stable but with a general trend of shrinking areal extent;(3) The LHMP in the Mid-Holocene(8500-7000 to 4000-3000 a BP)when permafrost degraded intensively and extensively, and shrank to the LLPMin;(4) Neoglaciation during the late Holocene(4000-3000 to 1000 a BP, when permafrost again expanded;(5) Medieval Warming Period(MWP) in the late Holocene(1000-500 a BP) when permafrost was in a relative decline;(6) Little Ice Age(LIA) in the late Holocene(500-100 a BP), when permafrost relatively expanded, and;(7) Recent warming(during the 20 th century), when permafrost continuously degraded and still is degrading. The paleo-climate, geography and paleopermafrost extents and other features were reconstructed for each of these seven periods.Huijun JIN Xiaoying JIN Ruixia HE Dongliang LUO Xiaoli CHANG Shaoling WANG Sergey S MARCHENKO Sizhong YANG Chaolu YI Shijie LI Stuart A HARRIS 2019Science China Earth Sciences2019,62,8:6
6Three Cases of COVID-19 Variant Delta With and Without Vaccination——Chengdu City,Sichuan Province,April-May,2021显示文摘On April 26,2021,a 33-year-old male Chinese sailor returning from India via Kathmandu,Nepal,tested positive for the coronavirus disease 2019(COVID-19)by Chengdu Customs and was confirmed positive by Chengdu CDC(Case A).On May 2,2021,a housewife in the same flight tested positive for COVID-19 by Pengzhou CDC in Sichuan Province during her quarantine period and was confirmed positive by Chengdu CDC the next day(Case B).Heng Chen Yi Mao Zhenhua Duan Liang Wang Yue Cheng Yingxue Dai Haixia Luo Wenjun Xie Shuangfeng Fan Yuzhen Zhou Jingpei Xu Lan Feng Liwen Hu Zhu Liu Xian Liang Liangshuang Jiang Xiaoli Tuo 2021China CDC weekly2021,3,25:5
7Development of Bionic Polymers显示文摘Xu Jian Xie Qiongdan Guo Xinlin Feng Lin Jiang Lei Tang Wenghong Luo Xiandong Zhang Xiaoli Han Charles C. 2004合成化学2004,12,z1:5
8Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting.Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu 2021Cancer Communications2021,41,9:5
9Synthesis of novel β-amino ketones containing a p-aminobenzoic acid moiety and evaluation of their antidiabetic activities显示文摘The synthesis of two series of β-amino ketones containing a p-aminobenzoic acid moiety (TM-1 and TM-2) using a modified protocol of the Mannich reaction is reported. The molecular structures of a total of tweenty three new target compounds were characterized by 1H NMR, 13C NMR, ESI-MS and HR-MS. Subsequently, their antidiabetic activities were screened in vitro. The α-glucodase inhibition (α-GI) activity of compound 1e reached a remarkable level of 66.50%. The peroxisome proliferatoractivated receptor (PPAR) relative activation activities of six compounds are above 80%, and in particular 2i displays an unprecedentedly high PPAR of 130.91%. The structure-activity relationships of the compounds were established. 2i is also subject to further in-depth investigation.TANG GuangXia YAN JuFang FAN Li XU Jin SONG XiaoLi JIANG Li LUO LingFei YANG DaCheng 2013Science China Chemistry2013,56,4:5
10Hydrothermal Synthesis of Cs_xWO_3 and the Effects of N_2 Annealing on its Microstructure and Heat Shielding Properties显示文摘Cesium tungsten bronze(Cs_xWO_3) powders were synthesized by hydrothermal reaction at 190 ℃ by using sodium tungstate and cesium carbonate as raw materials,and the effects of N_2 annealing on the microstructure and near-infrared(NIR) shielding as well as heat insulation properties of Cs_xWO_3 were investigated.The results indicated that the synthesized Cs_xWO_3 powders exhibited hexagonal Cs_(0.32)WO_3crystal structure,and subsequent N_2 annealing could further improve the crystallinity of CsxW03 particles.Moreover,the NIR shielding and heat insulation properties of Cs_xWO_3 could be further improved after N_2annealing at appropriate temperature for a period of time.Particularly,the 500 ℃-annealed Cs_xWO_3 products in the N_2 atmosphere showed the best NIR shielding and heat insulation properties.When the N_2 annealing temperature was higher than 700 ℃,the NIR shielding properties decreased again.The 800 ℃-annealed samples in the N_2 atmosphere showed higher visible light transmittance,however,the NIR shielding properties were lower than that of the non-annealed samples.Fei Shi Jingxiao Liu Xiaoli Dong Qiang Xu Jiayu Luo Hongchao Ma 2014Journal of Materials Science & Technology2014,30,4:5
11Light-triggered interfacial charge transfer and enhanced photodetection in CdSe/ZnS quantum dots/MoS_(2)mixed-dimensional phototransistors显示文摘Mix-dimensional van der Waals heterostructures(vdWHs)have inspired worldwide interests and efforts in the field of ad-vanced electronics and optoelectronics.The fundamental understanding of interfacial charge transfer is of vital import-ance for guiding the design of functional optoelectronic applications.In this work,type-Ⅱ0D-2D CdSe/ZnS quantum dots/MoS_(2)vdWHs are designed to study the light-triggered interfacial charge behaviors and enhanced optoelectronic performances.From spectral measurements in both steady and transient states,the phenomena of suppressed photolu-minescence(PL)emissions,shifted Raman signals and changed PL lifetimes provide strong evidences of efficient charge transfer at the 0D-2D interface.A series of spectral evolutions of heterostructures with various QDs overlapping concentrations at different laser powers are analyzed in details,which clarifies the dynamic competition between exciton and trion during an efficient doping of 3.9×10^(13)cm^(−2).The enhanced photoresponses(1.57×10^(4)A·W^(-1))and detectivities(2.86×10^(11)Jones)in 0D/2D phototransistors further demonstrate that the light-induced charge transfer is still a feasible way to optimize the performance of optoelectronic devices.These results are expected to inspire the basic understand-ing of interfacial physics at 0D/2D interfaces,and shed the light on promoting the development of mixed-dimensional op-toelectronic devices in the near future.Ziwei Li Wen Yang Ming Huang Xin Yang Chenguang Zhu Chenglin He Lihui Li Yajuan Wang Yunfei Xie Zhuoran Luo Delang Liang Jianhua Huang Xiaoli Zhu Xiujuan Zhuang Dong Li Anlian Pan 2021Opto-Electronic Advances2021,4,9:4
12Evolution of permafrost in Northeast Chinasince the Late Pleistocene显示文摘In Northeast China, permafrost advanced and retreated several times under the influences of fluctuating paleo-climates and paleo-environments since the Late Pleistocene. During the last 60 years, many new data were obtained and studies were conducted on the evolution of permafrost in Northeast China, but so far no systematic summary and review have been made. Based on sedimentary sequences, remains of past permafrost, paleo-flora and-fauna records, and dating data, permafrost evolution since the Late Pleistocene has been analyzed and reconstructed in this paper. Paleo-temperatures reconstructed from the remains of past permafrost and those from paleo-flora and-fauna are compared, and thus the southern limit of permafrost(SLP) in each climate period is inferred by the relationship of the permafrost distribution and the mean annual air/ground temperatures(MAAT/MAGT). Thus, the evolutionary history of permafrost is here divided into five stages:(1) the Late Pleistocene(Last Glaciation, or LG)(65 to 10–8.5 ka), the Last Glaciation Maximum(LGM, 21–13 ka) in particular, the coldest period in the latest history with a cooling of about 6~10 ?C, characterized by extensive occurrences of glaciation, flourishing Mammathas-Coelodonta Faunal Complex(MCFC), widespread aeolian deposits, and significant sea level lowering, and permafrost greatly expanded southwards almost to the coastal plains(37?N–41?N);(2) the Holocene Megathermal Period(HMP, 8.5–7.0 to 4.0–3.0 ka), 3~5 ?C warmer than today, permafrost retreated to about 52°N;(3) the Late Holocene Cold Period(Neoglaciation)(4.0–3.0 to 1.0–0.5 ka), a cooling of 1~3 ?C, some earlier thawed permafrost was refrozen or attached, and the SLP invaded southwards to 46?N;(4) the Little Ice Age(LIA, 500 to 100–150 a), the latest cold period with significant permafrost expansion; and(5) climate warming since the last century, during which Northeast China has undergone extensive permafrost degradation. The frequent and substantial expansions and retreats of permafrost have greatly impacted cold-region environments in Northeast China. North of the SLP during the HMP, or in the present continuous permafrost zone, the existing permafrost was largely formed during the LG and was later overlapped by the permafrost formed in the Neoglaciation. To the south, it was formed in the Neoglaciation. However, many aspects of permafrost evolution still await further investigations, such as data integration, numerical reconstruction, and merging of Chinese permafrost history with those of bordering regions as well as collaboration with related disciplines. Of these, studieson the evolution and degradation of permafrost during the past 150 years and its hydrological, ecological, and environmental impacts should be prioritized.HuiJun Jin XiaoLi Chang DongLiang Luo RuiXia He LanZhi Lu SiZhong Yang DongXin Guo XueMei Chen Stuart A.Harris 2016Research in Cold and Arid Regions2016,8,4:3
13Plasmonically engineered light-matter interactions in Aunanoparticle/MoS_(2) heterostructures for artificial optoelectronic synapse显示文摘Optoelectronic synaptic elements are emerging functional devices for the vigorous development of advanced neuromorphic computing technology in the post-Moore era.However,optoelectronic devices based on transition metal dichalcogenides(TMDs)are limited to their poor mobilities and weak light-matter interactions,which still hardly exhibit superior device performances in the application of artificial synapses.Here,we demonstrate the successful fabrication of Au nanoparticle-coupled MoS_(2)heterostructures via chemical vapor deposition(CVD),where the light absorption of MoS_(2)is greatly enhanced and engineered by plasmonic effects.Hot electrons are excited from Au nanoparticles,and then injected into MoS_(2)semiconductors under the light illumination.The plasmonically-engineered photo-gating effect at the metal-semiconductor junction is demonstrated to create optoelectronic devices with excellent synaptic behaviors,especially in ultra-sensitive excitatory postsynaptic current(EPSC,9.6×10^(-3)nA@3.4 nW·cm^(-2)),ultralow energy consumption(34.7 pJ),long-state retention time(>1,000 s),and tunable synaptic plasticity transitions.The material system of Au-nanoparticles coupled TMDs presents unique advantages for building artificial synapses,which may lead the future development of neuromorphic electronics in optical information sensing and learning.Zhuoran Luo Yunfei Xie Ziwei Li Yajuan Wang Lihui Li Ziyu Luo Chenguang Zhu Xin Yang Ming Huang Jianhua Huang Delang Liang Xiaoli Zhu Dong Li Anlian Pan 2022Nano Research2022,15,4:3
14Multifunctional Landscape Actor-Network Construction from the Perspective of Rural Tourism Experiences显示文摘During the construction of multifunctional landscape(MFL) actor-network, economic, social, and ecological functions presented significant differences, which resulted from the different roles and effects of various heterogeneous actors according to the tourism experience. In Hekou Village at the border area between China and North Korea, the roles and effects of heterogeneous actors during the MFL actor-network construction were analyzed by means of the analytic network process(ANP), which verified the Groundings-Entrepreneurship-Markets(GEM) theoretical framework of the MFL actor-network that assumed tourism experiences were core actors, and economic, social, and ecological landscape actors acted as support. Research results showed that in the MFL actornetwork construction, social and economic functions of landscapes were strong, while ecological and tourism experience functions were weak and that folk customs and land utilization were key actors of the MFL actor-network construction. In the MFL actor-network construction, actors played different roles and had different effects on the network. Intelligence facilities and rurality were critical to drive the MFL actor network translation process and pass through 'obligatory passage point'. By changing the interaction mode and intensity of the actors, the MFL actor-network could be promoted.ZHENG Liaoji WANG Huanyu LUO Yunyan ZHOU Xiaoli 2019Journal of Landscape Research2019,11,1:2
15Formation and tribology properties of polyfluoroal-kylmethacrylate film on the magnetic head surface显示文摘A polyfluoroalkylmethacrylate (PFAM) film has been coated on the surface of the magnetic head by a dipping coating method to modify the surface properties. The films were characterized by means of a time-of-flight secon- dary ion mass spectrometer (TOF-SIMS), contact angle measurement and atomic force microscopy (AFM). The re- sults indicate that the concentration of the solution is the main factor affecting the thickness, contact angle and surface topography of the film. The magnetic head with the PFAM film at a concentration of 500 ppm exhibits the best tribology properties, and the stiction between the magnetic head and the disk is no more than 2.4 g after 20000 contact start stop (CSS) cycles. Therefore, a fully covered PFAM film with few defects helps improve the tribology properties of the mag- netic head, and decrease the adsorbed contaminant on the magnetic head surface.HU Xiaoli ZHANG Chenhui LUO Jianbin WEN Shizhu 2005Chinese Science Bulletin2005,50,20:2
16Fast elimination of malaria by infectious source eradication with artemisinin-based compound显示文摘Malaria is one of the three most hazardous infectious diseases(HIV/AIDS,Malaria and tuberculosis)in the world.Since 1960,falciparum malaria gradually became resistant to original antimalarial drugs such as Chloroquine and Fansidar.With the global spread of drug-resistant falciparum malaria,morbidity and mortality increased greatly.InLiling Feng Xiaoli Luo Yaofang Zhou Xingbo Guo Guoqiao Li 2016Science China(Life Sciences)2016,59,1:2
17A high-quality sponge gourd(Luffa cylindrica)genome显示文摘Sponge gourd(Luffa cylindrica)is an important cultivated vegetable and medicinal plant in the family Cucurbitaceae.In this study,a draft genome sequence of the sponge gourd inbred line P93075 was analyzed.Using Illumina,PacBio,and 10×Genomics sequencing techniques as well as new assembly techniques such as FALCON and chromatin interaction mapping(Hi-C),a chromosome-scale genome of approximately 656.19 Mb,with an N50 scaffold length of 48.76 Mb,was generated.From this assembly,25,508 protein-coding gene loci were identified,and 63.81%of the whole-genome consisted of transposable elements,which are major contributors to the expansion of the sponge gourd genome.According to a phylogenetic analysis of conserved genes,the sponge gourd lineage diverged from the bitter gourd lineage approximately 41.6 million years ago.Additionally,many genes that respond to biotic and abiotic stresses were found to be lineage specific or expanded in the sponge gourd genome,as demonstrated by the presence of 462 NBS-LRR genes,a much greater number than are found in the genomes of other cucurbit species;these results are consistent with the high stress resistance of sponge gourd.Collectively,our study provides insights into genome evolution and serves as a valuable reference for the genetic improvement of sponge gourd.Haibin Wu Gangjun Zhao Hao Gong Junxing Li Caixia Luo Xiaoli He Shaobo Luo Xiaoming Zheng Xiaoxi Liu Jinju Guo Junqiu Chen Jianning Luo 2020Horticulture Research2020,7,1:2
18Constitutive model for high temperature deformation of titanium alloys using internal state variables显示文摘Jiao Luo Miaoquan Li Xiaoli Li Yanpei Shi 2010Mechanics of Materials2010,,2:2
19Overexpressed DNA-binding protein inhibitor 2 as an unfavorable prognosis factor promotes cell proliferation in nasopharyngeal carcinoma显示文摘现在的学习的目的是在鼻咽的癌(NPC ) 和它与 clinicopathological 特征的关联分析 DNA 有约束力的蛋白质禁止者 2 的表示(ID2 ) 。ID2 的表示显著地在 NPC 房间被增加,这被发现什么时候与那相比在 NP69 房间线。ID2 细胞质的表示的类似的水平在 NPC 被观察什么时候与那相比在非癌的鼻咽纸巾。然而,在原子核的 ID2 的水平在 NPC 被增加什么时候与那相比在正常鼻咽纸巾。而且,原子 ID2 的更高的表示水平显著地与肿瘤被联系尺寸(T 分类) ,淋巴节点转移(N 分类) ,和临床的舞台。有增加的 ID2 表示水平的病人与低 ID2 层次比那些有更差的全面幸存率。在由调停 lentiviral 的短发卡 RNA 的 NPC 房间线 SUNE1 的 ID2 表示的抑制能压制房间增长和殖民地形成,但是没破坏房间移植。由 RNA 干扰将 ID2 的表示击倒能下面调整蜗牛的表示,建议那支持 ID2 的房间生长,部分在 NPC 归因于蜗牛活动的规定。我们的学习证明 ID2 蛋白质的在表示上是在 NPC 支持房间增长的一个相反的预示的因素。Zhen Liu Jing Chen Weiren Luo Huiling Yang Aibing Wu Yan Zhen Xiaoli Yu Hao Wang Kaitai Yao 2012Acta Biochimica et Biophysica Sinica2012,44,6:2
20Preparation, characterization, and property of polyaniline/Prussian blue micro-composites in a low-temperature hydrothermal process显示文摘Xiaoli Zhang Chunhong Sui Jian Gong Rui Yang Yunqing Luo Lunyu Qu 2007Applied Surface Science2007,,22:1
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