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| 1 | The Performance of Whole Genome Amplification Methods and Next-Generation Sequencing for Pre-Implantation Genetic Diagnosis of Chromosomal Abnormalities显示文摘Reliable and accurate pre-implantation genetic diagnosis(PGD) of patient's embryos by next-generation sequencing(NGS) is dependent on efficient whole genome amplification(WGA) of a representative biopsy sample. However, the performance of the current state of the art WGA methods has not been evaluated for sequencing. Using low template DNA(15 pg) and single cells, we showed that the two PCR-based WGA systems Sure Plex and MALBAC are superior to the REPLI-g WGA multiple displacement amplification(MDA) system in terms of consistent and reproducible genome coverage and sequence bias across the 24 chromosomes, allowing better normalization of test to reference sequencing data. When copy number variation sequencing(CNV-Seq) was applied to single cell WGA products derived by either Sure Plex or MALBAC amplification, we showed that known disease CNVs in the range of 3e15 Mb could be reliably and accurately detected at the correct genomic positions. These findings indicate that our CNV-Seq pipeline incorporating either Sure Plex or MALBAC as the key initial WGA step is a powerful methodology for clinical PGD to identify euploid embryos in a patient's cohort for uterine transplantation. | Na Li Li Wang Hui Wang Minyue Ma Xiaohong Wang Yi Li Wenke Zhang Jianguang Zhang David S.Cram Yuanqing Yao | 2015 | Journal of Genetics and Genomics2015，42，4： | 13 |
| 2 | Trajectory tracking control of a VTOL unmanned aerial vehicle using offset-free tracking MPC显示文摘Designing a stable and robust flight control system for an Unmanned Aerial Vehicle(UAV)is an arduous task.This paper addresses the trajectory tracking control problem of a Ducted Fan UAV(DFUAV)using offset-free Model Predictive Control(MPC)technique in the presence of various uncertainties and external disturbances.The designed strategy aims to ensure adequate flight robustness and stability while overcoming the effects of time delays,parametric uncertainties,and disturbances.The six degrees of freedom DFUAV model is divided into three flight modes based on its airspeed,namely the hover,transition,and cruise mode.The Dryden wind turbulence is applied to the DFUAV in the linear and angular velocity component.Moreover,different uncertainties such as parametric,time delays in state and input,are introduced in translational and rotational components.From the previous work,the Linear Quadratic Tracker with Integrator(LQTI)is used for comparison to corroborate the performance of the designed controller.Simulations are computed to investigate the control performance for the aforementioned modes and different flight phases including the autonomous flight to validate the performance of the designed strategy.Finally,discussions are provided to demonstrate the effectiveness of the given methodology. | Tayyab MANZOOR Yuanqing XIA Di-Hua ZHAI Dailiang MA | 2020 | Chinese Journal of Aeronautics2020，33，7： | 10 |
| 3 | Branched tetraether lipids in Chinese soils:Evaluating the fidelity of MBT/CBT proxies as paleoenvironmental proxies显示文摘The ubiquitous occurrence of branched glycerol dialkyl glycerol tetraethers(br GDGTs) in soils has allowed development of new proxies for reconstruction of past climate and environment. The methylation and cyclization degrees of br GDGTs, expressed as MBT and CBT, respectively, are reported to be mainly controlled by mean annual air temperature(MAAT) and soil p H. However, the br GDGT-derived temperatures and soil p H scatter widely when data from different environmental conditions are considered. In this study, we collected over 300 soil samples from China, which are representative of humid(Xishuangbanna, Guangzhou, and Shanghai), semi-arid(Dongying) and semi-arid/arid(Lanzhou, Tibetan Plateau) regions. Collectively we have the most extensive dataset that broadly characterizes the distribution of br GDGTs according to climate zones in China. The overall data demonstrate that the MBT/CBT derived temperatures better match the measured MAATs in humid and non-alkaline regions than those from regions of low MAP(<400 mm/yr) and above neutral soil p H(>7.0–7.5). Similarly, CBT describes soil p H much better in humid and non-alkaline soils than in semi-arid/arid and alkaline soils; the semi-arid/arid and alkaline soils tend to show a positive correlation between soil p H and CBT, which contradicts that in the humid and non-alkaline soils. While soil p H, MAAT and mean annual precipitation(MAP) are dominating factors controlling the br GDGT distribution across all climate zones, conductivity, total organic carbon and total nitrogen, as well as soil water content can also play an important role locally. Removing br GDGT-II resulted in a revised CBT index that provides more accurate estimation of p H, especially in semi-arid/arid and alkaline soils. The overall Chinese dataset demonstrates that continental air temperature derived from br GDGT-proxies can vastly deviate from real measurements and should be used with extreme caution in paleo-climate or-environment studies. | ZHENG FengFeng ZHANG ChuanLun CHEN YuFei LI FuYan MA CenLing PU Yang ZHU YuanQing WANG YongLi LIU WeiGuo | 2016 | Science China Earth Sciences2016，59，7： | 10 |
| 4 | The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation显示文摘Wnt/-catenin 发信号在脊椎动物 embryogenesis 期间为背面腹的 patterning 的开始是必要的。母亲的 -catenin 在劈开阶段期间在背面的边缘的原子核积累,但是它为 dorsalization 的批评目标基因必需品是沉默的直到中间胞胚的转变(MBT ) 。这里,我们发现那 zebrafish net1,一个 guanine 核苷酸交换因素,明确地在 MBT,和行为以后在背面的边缘的分裂球被表示为一个 zygotic 因素支持背面的房间命运的说明。Loss-of-function 和 gain-of-function 实验证明 Net1 的 GEF 活动为在 zebrafish 胚胎和哺乳动物的房间发信号的 Wnt/-catenin 的激活被要求。Net1 分裂并且激活激活在 MBT 以后引起 -catenin 的 S675 的 phosphorylation 的 PAK1 dimers,和 PAK1 kinase,它最终导致下游的目标基因的抄写。在摘要,我们的结果表明调整 Net1 的 -catenin 激活在 zebrafish 开发期间在背面的轴形成起一个关键作用。 | Shi Wei Miaomiao Dai Zhaoting Liu Yuanqing Ma Hanqiao Shang Yu Cao Qiang Wang | 2017 | Cell Research2017，27，2： | 6 |
| 5 | Expression Patterns of Cytochrome P450 Aromatase Genes During Ovary Development and Their Responses to Temperature Stress in Female Yellow Catfish (Pelteobagrus fulvidraco)显示文摘Cytochrome P450 aromatase(P450arom)plays a pivotal role in ovary development.In this study,we used semi-quanti-tative reverse transcription PCR(RT-PCR)to analyze spatiotemporal expressions of two P450arom genes(CYP19A and CYP19B)and their responses to temperature stress in female yellow catfish(Pelteobagrus fulvidraco).Tissue distribution pattern of CYP19 showed that CYP19B was abundantly expressed in fish brain and ovary(brain > ovary),but weakly in intestines,whereas CYP19A was exclusively expressed in ovary.Semi-quantitative RT-PCR analyses showed high transcript abundance of both CYP19A and CYP19B in the ovarian reproductive cycle,corresponding with serum estradiol-17β(E2)levels.Increases in aromatases,serum E2 and testosterone(T)levels in fish exposed to higher temperature indicated stimulation of ovarian maturation and recrudescence by heat stress in stages Ⅱ and Ⅴ during the ovarian cycle,whereas associated decreases in stage Ⅲ suggested vitellogenesis inhibition by heat stress.Gene expression of CYP19 was closely related to levels of serum E2.Results demonstrated CYP19 played a crucial role in the reproductive cycle of female yellow catfish.Different temperature stress affected CYP19 gene expression in the fish ovarian re-productive cycle.Associated P450arom genes could be useful for studying physiological aspects of yellow catfish. | LIU Miao WEN Haishen HE Feng LI Jifang SHI Dan HU Jian ZHANG Yuanqing MA Ruiqin MU Weijie QI Baoxia | 2011 | Journal of Ocean University of China2011，10，4： | 5 |
| 6 | Spatial and temporal distribution of precipitation based on corrected TRMM data around the Hexi Corridor,China显示文摘Accurate rainfall distribution is difficult to acquire based on limited meteorological stations,especially in remote areas like high mountains and deserts.The Hexi Corridor and its adjacent regions(including the Qilian Mountains and the Alxa Plateau)are typical districts where there are only 30 available rain gauges.Tropical Rainfall Measuring Mission(TRMM)data provide a possible solution.After precision analysis of monthly 0.25 degree resolution TRMM 3B43 data from 1998 to 2012,we find that the correlations between TRMM 3B43 estimates and rain gauge precipitation are significant overall and in each station around the Hexi Corridor; however,the biases of annual precipitation differ in different stations and are seriously overestimated in most of the sites.Thus,Inverse Distance Weighting(IDW)interpolation method was used to rectify TRMM data based on the difference between TRMM 3B43 estimates and rain gauge observations.The results show that rectified TRMM data present more details than rain gauges in remote areas where there are few stations,although they show high coherence of distribution.Precipitation decreases from southeast to northwest on an annual and seasonal scale.There are three rainfall centers(>500mm)including Menyuan,Qilian and Toson Lake,and two low rainfall centers(<50mm)including Dunhuang and Ejin Banner.Meanwhile,precipitation in most of the study area presents an increasing trend; especially in northern Qilian Mountains(>5mm/a),Badain Jaran Desert(>2mm/a),Toson Lake(>20mm/a)and Qingtu Lake(>20mm/a)which shows a significant increasing trend,while precipitation in Hala Lake(<-2 mm/a)and Tengger Desert(<-3mm/a)demonstrates a decreasing trend. | Tao Zhang YuanQing He Jian Ma Juan Pang | 2014 | Research in Cold and Arid Regions2014，6，2： | 4 |
| 7 | Fishbone-like platinum-nickel nanowires as an efficient electrocatalyst for methanol oxidation显示文摘Platinum(Pt)-based electrocatalyst with low Pt content and high electrocatalytic performance is highly desired in fuel cell applications.Herein,we demonstrated that platinum-nickel(Pt-Ni)nanowires with an average composition of PtNi3 and a fishbone structure can be readily synthesized and used as an efficient electrocatalyst toward methanol oxidation reaction(MOR).The PtNi3 fishbone-like nanowires(PtNi3-FBNWs)present features such as richer Pt on the surface than in the bulk,high-index facets on the rough surface,and polyhedral facets at the ends of side chains.Such compositional and structural features could be determinative to the enhanced performance in the electrocatalysis of MOR.Compared with commercial 20%Pt/carbon black(Pt/C),the specific activity and mass activity of the PtNi3-FBNWs are enhanced by approximately 4.76 and 3.02 times,respectively.The stability of electrocatalysis is significantly improved as well.Such comprehensive enhancement indicates that the PtNi3-FBNWs would be a promising candidate toward MOR in fuel cells. | Jinquan Chang Luting Song Yuanqing Xu Yanhong Ma Cheng Liang Wenyu Jiang Yong Zhang | 2020 | Nano Research2020，13，1： | 3 |
| 8 | Secure design for cloud control system against distributed denial of service attack显示文摘现在,云计算的开发把力量给了抑制资源的网络控制系统(NCS ) 采购重计算到云服务器。然而,云计算的发展关于在云和控制系统之间的电子物理的连接生产了许多安全挑战。在控制系统和云服务者之间的连接能受到分布式的拒绝服务(DDoS ) 由一个攻击者的攻击使动摇 NCS。在这份报纸,我们将由为如此的系统造安全机制处理这个问题。我们将为 NCS 的更好稳定的性能设计一条察觉途径和一条缓解途径。为了在 DDoS 的时候保证 NCS 的稳定性,攻击,当有从云可得到的不再实时的答案时,我们将也为云控制系统(CCS ) 设计切换的机制(SM ) 。最后,我们将把建议机制用于无人的 arial 车辆(UAV ) 。我们的模拟结果证明机制在 DDoS 攻击下面在 NCS 的稳定性和保护工作很好。 | Yasir ALI Yuanqing XIA Liang MA Ahmad HAMMAD | 2018 | Control Theory and Technology2018，16，1： | 3 |
| 9 | A PGD Pregnancy Achieved by Embryo Copy Number Variation Sequencing with Confirmation by Non-Invasive Prenatal Diagnosis显示文摘Aneuploidy rates in embryos produced by assisted reproductive technologies commonly exceed 50%,particularly in couples where the woman is of advanced maternal age or has experienced repeated implantation failure(Harper et al.,2012).Pre-implantation genetic diagnosis(PGD)conducted at many fertility clinics worldwide is now | Hui Wang Li Wang Minyue Ma Zhuo Song Jianguang Zhang Genming Xu Junmei Fan Na Li David S.Cram Yuanqing Yao | 2014 | Journal of Genetics and Genomics2014，41，8： | 3 |
| 10 | Geographic modeling and simulation systems for geographic research in the new era: Some thoughts on their development and construction显示文摘Regionality,comprehensiveness,and complexity are regarded as the basic characteristics of geography.The exploration of their core connotations is an essential way to achieve breakthroughs in geography in the new era.This paper focuses on the important method in geographic research:Geographic modeling and simulation.First,we clarify the research requirements of the said three characteristics of geography and its potential to address geo-problems in the new era.Then,the supporting capabilities of the existing geographic modeling and simulation systems for geographic research are summarized from three perspectives:Model resources,modeling processes,and operational architecture.Finally,we discern avenues for future research of geographic modeling and simulation systems for the study of regional,comprehensive and complex characteristics of geography.Based on these analyses,we propose implementation architecture of geographic modeling and simulation systems and discuss the module composition and functional realization,which could provide theoretical and technical support for geographic modeling and simulation systems to better serve the development of geography in the new era. | Min CHEN Guonian LV Chenghu ZHOU Hui LIN Zaiyang MA Songshan YUE Yongning WEN Fengyuan ZHANG Jin WANG Zhiyi ZHU Kai XU Yuanqing HE | 2021 | Science China Earth Sciences2021，64，8： | 3 |
| 11 | Nodal Promotes mir206 Expression to Control Convergence and Extension Movements During Zebrafish Gastrulation显示文摘Nodal,a member of the transforming growth factor b(TGF-b)superfamily,has been shown to play a role in mesendoderm induction and gastrulation movements.The activity of Nodal signaling can be modulated by microRNAs(miRNAs)as previously reported,but little is known about which miRNAs are regulated by Nodal during gastrulation.In the present study,we found that the expression of mir206,one of the most abundant miRNAs during zebrafish early embryo development,is regulated by Nodal signaling.Abrogation of Nodal signal activity results in defective convergence and extension(CE)movements,and these cell migration defects can be rescued by supplying an excess of mir206,suggesting that mir206 acts downstream of Nodal signaling to regulate CE movements.Furthermore,in mir206 morphants,the expression of cell adhesion molecule E-cadherin is significantly increased,while the key transcriptional repressor of E-cadherin,snail1a,is depressed.Our study uncovers a novel mechanism by which Nodal-regulated mir206 modulates gastrulation movements in connection with the Snail/E-cadherin pathway. | Xiuli Liu Yuanqing Ma Congwei Zhang Shi Wei Yu Cao Qiang Wang | 2013 | Journal of Genetics and Genomics2013，40，10： | 2 |
| 12 | Cloning and Expression Analysis of vasa During the Reproductive Cycle of Korean Rockfish, Sebastes schlegeli显示文摘Vasa, which is a conserved member of the DEAD-box protein family, plays an indispensable role in primordial germ cell proliferation. However, the expression of vasa gene during the reproductive cycle in ovoviviparous fish has not been documented. In this study, the full-length sequence of vasa was obtained from the ovary of Korean rockfish (Sebastes schlegeli) using reverse transcription-PCR and rapid amplification of cDNA ends. The Vasa with a mature protein of 650 amino acids showed greatest homology (84%) with giant gourami (Osphronemus goramy) and Pacific bluefin tuna (Thunnus orientalis). The expression of vasa mRNA in Korean rockfish was detected in gonads only, suggesting its specific role in gonadal development. In addition, seasonal changes in the vasa expression levels were examined in gonads by quantitative real-time PCR. The vasa transcript levels in adult testis were found higher during spermatogenesis than during spermiation. The vasa transcript levels remained relatively high at the early ovary stage but declined during ovary maturation in adult female fish. These results suggest that the vasa gene play an important role in spermatogenesis and early oogenesis during the reproductive cycle of Korean rockfish. | MU Weijie WEN Haishen HE Feng LI Jifang LIU Miao MA Ruiqin ZHANG Yuanqing HU Jian QI Baoxia | 2013 | Journal of Ocean University of China2013，12，1： | 2 |
| 13 | Biomass-derived nitrogen self-doped porous activation carbon as an effective bifunctional electrocatalysts显示文摘The strategy of adopting cheap precursors or abundant resources,which can be obtained directly from nature,is a simple and excellent method of introducing accessible research into environmentally friendly development.Moreover,this is also an urgent requirement for the sustainable development of green technology.Herein,we introduce a simplistic and expandable method to prepare metal-free biomassderived nitrogen self-doped porous activation carbon(N-PAC) with large specific surface area(S_(BET)=1300.58 m^(2)/g).Moreover,the manufactural electrocatalysts exhibit prominent oxygen reduction reaction(ORR) performance in all PH values.As compared with the commercial Pt/C catalyst,the N-PAC/800 with a positive onset potential at 10 mA/cm^(2)(0.93 V),half-wave potential(0.87 V),and limiting current(6.34 mA/cm^(2)) bring to light excellent catalytic stability,selectivity,and much-enhanced methanol tolerance.Furthermore,the prepared electrocatalysts possess considerable hydrogen evolution reaction(HER) performance with a less onset potential of 0.218 V(acidic medium) and0.271 V(alkaline medium) respectively,which can show similar catalytic activity across the whole pH range.Such bifunctional electrocatalyst,with excellent electrocatalytic properties,resource-rich,low cost,and environmental-friendly,hold a promising application in energy conversion and reserve. | Yuanqing Sun Yiming Ouyang Jiaqing Luo Huihui Cao Xiang Li Jingwen Ma Jian Liu Yuanhao Wang Lin Lu | 2021 | Chinese Chemical Letters2021，32，1： | 1 |
| 14 | Directly wireless communication of human minds via non-invasive brain-computer-metasurface platform显示文摘Brain-computer interfaces(BCIs),invasive or non-invasive,have projected unparalleled vision and promise for assisting patients in need to better their interaction with the surroundings.Inspired by the BCI-based rehabilitation technologies for nerve-system impairments and amputation,we propose an electromagnetic brain-computer-metasurface(EBCM)paradigm,regulated by human’s cognition by brain signals directly and non-invasively.We experimentally show that our EBCM platform can translate human’s mind from evoked potentials of P300-based electroencephalography to digital coding information in the electromagnetic domain non-invasively,which can be further processed and transported by an information metasurface in automated and wireless fashions.Directly wireless communications of the human minds are performed between two EBCM operators with accurate text transmissions.Moreover,several other proof-of-concept mind-control schemes are presented using the same EBCM platform,exhibiting flexibly-customized capabilities of information processing and synthesis like visual-beam scanning,wave modulations,and pattern encoding. | Qian Ma Wei Gao Qiang Xiao Lingsong Ding Tianyi Gao Yajun Zhou Xinxin Gao Tao Yan Che Liu Ze Gu Xianghong Kong Qammer HAbbasi Lianlin Li Cheng‑Wei Qiu Yuanqing Li Tie Jun Cui | 2022 | eLight2022，2，1： | 1 |
| 15 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 16 | Coastal wetland hyperspectral classification under the collaborative of subspace partition and infinite probabilistic latent graph ranking显示文摘The abundance of spectral information provided by hyperspectral imagery offers great benefits for many applications.However,processing such high-dimensional data volumes is a challenge because there may be redundant bands owing to the high interband correlation.This study aimed to reduce the possibility of“dimension disaster”in the classification of coastal wetlands using hyperspectral images with limited training samples.The study developed a hyperspectral classification algorithm for coastal wetlands using a combination of subspace partitioning and infinite probabilistic latent graph ranking in a random patch network(the SSP-IPLGR-RPnet model).The SSP-IPLGR-RPnet approach applied SSP techniques and an IPLGR algorithm to reduce the dimensions of hyperspectral data.The RPnet model overcame the problem of dimension disaster caused by the mismatch between the dimensionality of hyperspectral bands and the small number of training samples.The results showed that the proposed algorithm had a better classification performance and was more robust with limited training data compared with that of several other state-of-the-art methods.The overall accuracy was nearly 4%higher on average compared with that of multi-kernel SVM and RF algorithms.Compared with the EMAP algorithm,MSTV algorithm,ERF algorithm,ERW algorithm,RMKL algorithm and 3D-CNN algorithm,the SSP-IPLGR-RPnet algorithm provided a better classification performance in a shorter time. | HU YaBin REN GuangBo MA Yi YANG JunFang WANG JianBu AN JuBai LIANG Jian MA YuanQing SONG XiuKai | 2022 | Science China(Technological Sciences)2022，65，4： | 0 |
| 17 | Mutations in Exons of the CYP17-Ⅱ Gene Affect Sex Steroid Concentration in Male Japanese Flounder(Paralichthys olivaceus)显示文摘As a specific gene of fish,cytochrome P450c17-Ⅱ(CYP17-Ⅱ) gene plays a key role in the growth,development and reproduction level of fish.In this study,the single-stranded conformational polymorphism(SSCP) technique was used to characterize polymorphisms within the coding region of CYP17-Ⅱ gene in a population of 75 male Japanese flounder(Paralichthys olivaceus).Three single nucleotide polymorphisms(SNPs) were identified in CYP17-Ⅱ gene of Japanese flounder.They were c.G594A(p.G188R),c.G939A and c.G1502A(p.G490D).SNP1(c.G594A),located in exon 4 of CYP17-Ⅱ gene,was significantly associated with gonadosomatic index(GSI).Individuals with genotype GG of SNP1 had significantly lower GSI(P < 0.05) than those with geno-type AA or AG.SNP2(c.G939A) located at the CpG island of CYP17-Ⅱ gene.The mutation changed the methylation of exon 6.Indi-viduals with genotype AA of SNP2 had significantly lower serum testosterone(T) level and hepatosomatic index(HSI) compared to those with genotype GG.The results suggested that SNP2 could influence the reproductive endocrine of male Japanese flounder.How-ever,the SNP3(c.G1502A) located in exon 9 did not affect the four measured reproductive traits.This study showed that CYP17-Ⅱ gene could be a potentially useful candidate gene for the research of genetic breeding and physiological aspects of Japanese flounder. | MA Ruiqin HE Feng WEN Haishen LI Jifang SHI Bao SHI Dan LIU Miao MU Weijie ZHANG Yuanqing HU Jian HAN Weiguo ZHANG Jianan WANG Qingqing YUAN Yuren LIU Qun | 2012 | Journal of Ocean University of China2012，11，1： | 0 |
| 18 | Gain-enhanced reconfigurable radiation array with mechanically driven system and directive elements显示文摘In the artificial intelligence-driven modern wireless communication system,antennas are required to be reconfigurable in terms of size according to changing application scenarios.However,conventional antennas with constant phase distributions cannot achieve enhanced gains in different reconfigurable sizes.In this paper,we propose a mechanically reconfigurable radiation array(RRA)based on miniaturized elements and a mechanically reconfigurable system to obtain gain-enhanced antennas in compact and deployed states.A five-element RRA with a phase-reconfigurable center element is designed and analyzed theoretically.The experimental sample has been fabricated,driven by a deployable frame with only one degree of freedom to realize the size and phase distribution reconfiguration simultaneously to validate the enhanced gains of RRA.The proposed RRA can be tessellated into larger arrays to achieve higher gains in other frequency regimes,such as terahertz or photonics applications with nanometer fabrication technology. | Abubakar M.SADIQ Yuanqing GU Yu LUO Yan CHEN Kaixue MA | 2022 | Frontiers of Mechanical Engineering2022，17，4： | 0 |
| 19 | Single-cell Sequencing Reveals Clearance of Blastula Chromosomal Mosaicism in In Vitro Fertilization Babies显示文摘Although chromosomal mosaic embryos detected by trophectoderm(TE)biopsy offer healthy embryos available for transfer,high-resolution postnatal karyotyping and chromosome testing of the transferred embryos are insufficient.Here,we applied single-cell multi-omics sequencing for seven infants with blastula chromosomal mosaicism detected by TE biopsy.The chromosome ploidy was examined by single-cell genome analysis,with the cellular identity being identified by single-cell transcriptome analysis.A total of 1616 peripheral leukocytes from seven infants with embryonic chromosomal mosaicism and three control ones with euploid TE biopsy were analyzed.A small number of blood cells showed copy number alterations(CNAs)on seemingly random locations at a frequency of 0%-2.5%per infant.However,none of the cells showed CNAs that were the same as those of the corresponding TE biopsies.The blastula chromosomal mosaicism may be fully self-corrected,probably through the selective loss of the aneuploid cells during development,and the transferred embryos can be born as euploid infants without mosaic CNAs corresponding to the TE biopsies.The results provide a new reference for the evaluations of transferring chromosomal mosaic embryos in certain situations. | Yuan Gao Jinning Zhang Zhenyu Liu Shuyue Qi Xinmeng Guo Hui Wang Yanfei Cheng Shuang Tian Minyue Ma Hongmei Peng Lu Wen Fuchou Tang Yuanqing Yao | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 0 |
| 20 | Distribution and invasion of Spartina alterniflora within the Jiaozhou Bay monitored by remote sensing image显示文摘Spartina alterniflora as an alien invasive plant,poses a serious threat to the ecological functions of the coastal wetland of the Jiaozhou Bay.As of 2019,the distribution area of S.alterniflora in the Jiaozhou Bay has reached more than 500 hm^(2).For this reason,combined with field surveys,remote sensing monitoring of the invasion S.alterniflora in the Jiaozhou Bay has been carried out.To accurately identify S.alterniflora within the Jiaozhou Bay coastal wetland,we used a new method which is an implement of deep convolutional neural network,and by which we got a higher accuracy than the traditional method.Based on distribution of S.alterniflora extracted by the proposed method,the temporal and spatial distribution characteristics of S.alterniflora were analyzed.And then combined with environmental factors,the invasion mechanism of S.alterniflora in the Jiaozhou Bay was analyzed in detail.From the monitoring results,it can be seen that S.alterniflora in Jiaozhou Bay is mainly distributed in the beaches near the Yanghe River Estuary and its southern side,the Dagu River Estuary and the Nügukou.Spartina alterniflora first broke out near the Yanghe River Estuary and gradually spread to the tidal flats near the Nügukou.The Dagu River Estuary is dominated by S.anglica,whose area has not changed much over the years,and a small amount of S.alterniflora has invaded later. | Jianbu Wang Zhaoyang Lin Yuanqing Ma Guangbo Ren Zijun Xu Xiukai Song Yi Ma Andong Wang Yajie Zhao | 2022 | Acta Oceanologica Sinica2022，41，6： | 0 |
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