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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Advances in metal halide perovskite lasers: synthetic strategies, morphology control, and lasing emission显示文摘.In the past decade,lead halide perovskites have emerged as potential optoelectronic materials in the fields of light-emitting diode,solar cell,photodetector,and laser,due to their low-cost synthesis method,tunable bandgap,high quantum yield,large absorption,gain coefficient,and low trap-state densities.In this review,we present a comprehensive discussion of lead halide perovskite applications,with an emphasis on recent advances in synthetic strategies,morphology control,and lasing performance.In particular,the synthetic strategies of solution and vapor progress and the morphology control of perovskite nanocrystals are reviewed.Furthermore,we systematically discuss the latest development of perovskite laser with various fundamental performances,which are highly dependent on the dimension and size of nanocrystals.Finally,considering current challenges and perspectives on the development of lead halide perovskite nanocrystals,we provide an outlook on achieving high-quality lead perovskite lasers and expanding their practical applications. | Zhiping Hu Zhengzheng Liu Zijun Zhan Tongchao Shi Juan Du Xiaosheng Tang Yuxin Leng | 2021 | Advanced Photonics2021，3，3： | 5 |
| 3 | Study on the propagation of coupling shock waves with phase transition under combined tension-torsion impact loading显示文摘Phase transition can strongly change the stress wave propagation features. In this paper, the characteristic wave propagation under combined tension and torsion impact loading was studied with a simplified constitutive model of phase transition considering both pressure and shear stress. The results showed that for loading from the austenitic phase to the mixed phase, the wave propagation was similar to that in the elasto-plastic materials. However, for an instantaneous loading from the austenitic phase or mixed phase directly to the martensitic phase, a coupling shock wave(CSHW) with phase transition was predicted due to the second phase strengthening effect, which has barely been studied before. Through analysis of the constitutive equations with phase transition and the discontinuity conditions of shock waves, the control equations of the generalized Hugoniot curve was obtained and the CSHW problem with phase transition was solved analytically. An independent numerical simulation of step loading along a NiTi thin walled tube suffering a combined tension-torsion impact loading was given to prove the existence of CSHW. The simulation discloses the formation mechanism of CSHW and the adjusting process of the stress state ahead of CSHW, which reflects the intrinsic characteristic of materials with strong nonlinear constitutive behavior. | WANG Bo TANG ZhiPing | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，10： | 5 |
| 4 | Advances in the Coenzyme Q10 Biosynthesis Pathway in Rhodobacter sphaeroides and the Enhancement of Coenzyme Q10 Production Based on Metabolic Engineering显示文摘Coenzyme Q10 is widely used in food,cosmetics and pharmaceuticals,possessing a broad market.Rhodobacter sphaeroides is enriched in natural coenzyme Q10 and is becoming an important microorganism for producing natural coenzyme Q10.The paper reviewed the biosynthesis pathways of coenzyme Q10 in R.sphaeroides and the advances in enhancement of coenzyme Q10 production in R.sphaeroides based on metabolic engineering. | Kuo TANG Zhiping ZHAO | 2019 | Agricultural Biotechnology2019，8，4： | 4 |
| 5 | Quasicrystalline Phase in As-cast Mg-Zn-Y-Zr Alloy显示文摘An icosahedral phase in as-cast Mg 5. 78Zn-0.89Y-0.48Zr (wt-%) alloy has been identified with transmission electron microscope (TPM) The selected area diffraction patterns (SADP) from the phase show a five-fold symmetry of a quasicrystalline structure. The energy dispersive X-ray spectra (EDXS) indicate that the quaternary phase has a chemical composition of 67.6Zn-1 9.4Mg-8,1 Y-4 9Zr in at -% | Yali TANG Ningfu SHEN and Xin YUAN (Research Center for Materials, Zhengzhou Institute of Technology, Zhengzhou, 450002, China)Zhiping LUO and Shaoqing ZHANG (Institute of Aeronautical Materials, Beijing,100095, China)(To whom correspondence should be ad | 1994 | Journal of Materials Science & Technology1994，10，4： | 4 |
| 6 | Mechanisms of MYB-bHLH-WD40 Complex in the Regulation of Anthocyanin Biosynthesis in Plants显示文摘Anthocyanins are main coloring substances in plants with various functions such as antioxidant,preventing cardiovascular diseases,and inhibiting oncogenesis. The regulation of transcriptional levels plays a decisive role in the biosynthesis of anthocyanins. Studies have shown that the transcriptional levels of anthocyanins are mainly regulated by MYB-b HLH-WD40 ternary complex. This paper summarized the structure characteristics of MYB-b HLH-WD40 ternary complex and its regulatory role in anthocyanin biosynthesis pathway,focusing on the regulation mechanism of several important model plants by MYB-b HLH-WD40 complex. | Xin NIE Yang ZHAO Li ZHANG Yi TANG Juan WANG Zhiping ZHAO | 2015 | Agricultural Biotechnology2015，4，3： | 2 |
| 7 | Organic–inorganic hybrid perovskite scintillators for mixed field radiation detection显示文摘Sensitive and fast detection of neutrons and gamma rays is vital for homeland security,high-energy physics,and proton therapy.Fast-neutron detectors rely on light organic scintillators,andγ-ray detectors use heavy inorganic scintillators and semiconductors.Efficient mixed-field detection using a single material is highly challenging due to their contradictory requirements.Here we report hybrid perovskites(C_(8)H_(12)N)_(2)Pb(Br_(0.95)Cl_(0.05))_(4)that combine light organic cations and heavy inorganic skeletons at a molecular level to achieve unprecedented performance for mixed-field radiation detection.High neutron absorption due to a high density of hydrogen,strong radiative recombination within the highly confined[PbX_(6)]^(4-)layer,and sub-nanometer distance between absorption sites and radiative centers,enable a light yield of 41000 photons/MeV,detection pulse width of 2.97 ns and extraordinary linearity response toward both fast neutrons andγ-rays,outperforming commonly used fast-neutron scintillators.Neutron energy spectrum,time-of-flight based fast-neutron/γ-ray discrimination and neutron yield monitoring were all successfully achieved using(C_(8)H_(12)N)_(2)Pb(Br_(0.95)Cl_(0.05))_(4)detectors.We further demonstrate the monitoring of reaction kinetics and total power of a nuclear fusion reaction.We envision that molecular hybridized scintillators open a new avenue for mixed-field radiation detection and imaging. | Mengling Xia Guangda Niu Linyue Liu Runlong Gao Tong Jin Pengying Wan Weicheng Pan Xianpeng Zhang Zuoxiang Xie Sam Teale Zenghua Cai Jiajun Luo Shan Zhao Haodi Wu Shiyou Chen Zhiping Zheng Qingguo Xie Xiaoping Ouyang Edward HSargent Jiang Tang | 2022 | InfoMat2022，4，9： | 2 |
| 8 | Mode selection and high-quality upconversion lasing from perovskite CsPb2Br5 microplates显示文摘In recent years,halide perovskite nanostructures have had great advances and have opened up a bright future for micro/nanolasers.However,upconversion lasing by two-photon excitation with mode selection and high quality factor in one device is still rarely reported.Herein,two lasing modes are demonstrated in the all-inorganic perovskite CsPb2Br5 microplates with subwavelength thickness and uniform square shape.The net optical gain is quickly established in less than 1 ps and persists more than 30 ps,revealed by ultrafast transient absorption spectroscopy.The temperature-dependent low-threshold amplified spontaneous emission confirms the net gain for stimulated emission with a high characteristic temperature of 403 K,far surpassing the all-inorganic CsPbBr3 semiconductor gain media.Remarkably,upconversion lasing based on two kinds of microcavity effects,Fabry–Pérot and whispering-gallery modes,from the microplates at room temperature is successfully achieved with a low threshold operating in multi-or single-mode,respectively.Surprisingly,the quality factor(~3551)is among the best values obtained from perovskite micro/nanoplate upconversion lasers without an external cavity.Moreover,the highly stable chromaticity with color drift only less than 0.1 nm also outbalances the all-inorganic CsPbBr3 ones.These superior performances of CsPb2Br5 microplate lasing with a facile solution synthesis procedure will offer a feasible structure to fabricate specific functionalities for high-performance frequency upconversion micro/nanoscale photonic integrated devices. | ZHENGZHENG LIU CHUNWEI WANG ZHIPING HU JUAN DU JIE YANG ZEYU ZHANG TONGCHAO SHI WEIMIN LIU XIAOSHENG TANG AND YUXIN LENG | 2020 | Photonics Research2020，8，9： | 2 |
| 9 | Water Distribution and Removal along the Flow Channel in Proton Exchange Membrane Fuel Cells显示文摘Distribution expressions of total gas pressure and partial water vapor pressure along the channel direction were established based on lumped model by analyzing pressure loss in the channel and gas diffusion in the layer. The mechanism of droplet formation in the flow channel was also analyzed. Effects of the relative humidity, working temperature and stoichiometry on liquid water formation were discussed in detail. Moreover, the force equilibrium equation of the droplet in the flow channel was deduced, and the critical flow velocity for the water droplet removal was also addressed. The experimental results show that the threshold position of the liquid droplet is far from the inlet with the increase of temperature, and it decreases with the increase of the inlet total pressure. The critical flow velocity decreases with the increase of the radius and the working pressure. | 丁刚强 TANG Heqing LUO Zhiping 涂正凯 PEI Houchang LIU Zhichun LIU Wei | 2013 | Journal of Wuhan University of Technology(Materials Science)2013，28，2： | 2 |
| 10 | Quantitative Precipitation Forecasting Using Multi-Model Blending with Supplemental Grid Points:Experiments and Prospects in China显示文摘Quantitative Precipitation Forecast(QPF)is a challenging issue in seamless prediction.QPF faces the following difficulties:(i)single rather than multiple model products are still used;(ii)most QPF methods require long-term training samples not easily available,and(iii)local features are insufficiently reflected.In this work,a multi-model blending(MMB)algorithm with supplemental grid points(SGPs)is experimented to overcome these shortcomings.The MMB algorithm includes three steps:(1)single-model bias-correction,(2)dynamic weight MMB,and(3)light-precipitation elimination.In step 1,quantile mapping(QM)is used and SGPs are configured to expand the sample size.The SGPs are chosen based on similarity of topography,spatial distance,and climatic characteristics of local precipitation.In step 2,the dynamic weight MMB uses the idea of ensemble forecasting:a precipitation process can be forecast if more than 40% of the models predict such a case;moreover,threat score(TS)is used to update the weights of ensemble members.Finally,in step 3,the number of false alarms of light precipitation is reduced,thus alleviating unreasonable expansion of the precipitation area caused by the blending of multiple models.Verification results show that using the MMB algorithm has effectively improved the TS and bias score(BS)for blended 6-h QPF.The rate of increase in TS for heavy rainfall(25-mm threshold)reaches 20%-40%;in particular,the improvement has reached 47.6% for forecast lead time of 24 h,compared with the ECMWF model.Meanwhile,the BS is closer to 1,which is better than any single-model forecast.In sum,the QPF using MMB with SGPs shows great potential to further improve the present operational QPF in China. | Yu WANG Kan DAI Zhiping ZONG Yue SHEN Ruixia ZHAO Jian TANG Couhua LIU | 2021 | Journal of Meteorological Research2021，35，3： | 2 |
| 11 | Laser micro-impulse torsion pendulum显示文摘 | Li Jing Tang Zhiping | 2005 | China Optics Letters2005，，： | 1 |
| 12 | New Algorithm Rules Out Acute-on-chronic Liver Failure Development within 28 Days from Acute Decompensation of Cirrhosis显示文摘Background and Aims:Approximately 10%of patients with acute decompensated(AD)cirrhosis develop acute-on-chronic liver failure(ACLF)within 28 days.Such cases have high mortality and are difficult to predict.Therefore,we aimed to establish and validate an algorithm to identify these patients on hospitalization.Methods:Hospitalized patients with AD who developed ACLF within 28 days were considered pre-ACLF.Organ dysfunction was defined accord-ing to the chronic liver failure-sequential organ failure as-sessment(CLIF-SOFA)criteria,and proven bacterial infec-tion was taken to indicate immune system dysfunction.A retrospective multicenter cohort and prospective one were used to derive and to validate the potential algorithm,re-spectively.A miss rate of<5%was acceptable for the calcu-lating algorithm to rule out pre-ACLF.Results:In the deri-vation cohort(n=673),46 patients developed ACLF within 28 days.Serum total bilirubin,creatinine,international normalized ratio,and present proven bacterial infection at admission were associated with the development of ACLF.AD patients with≥2 organ dysfunctions had a higher risk for pre-ACLF patients[odds ratio=16.58195%confidence interval:(4.271-64.363),p<0.001].In the derivation co-hort,67.5%of patients(454/673)had≤1 organ dysfunction and two patients(0.4%)were pre-ACLF,with a miss rate of 4.3%(missed/total,2/46).In the validation cohort,65.9%of patients(914/1388)had≤1 organ dysfunction,and four(0.3%)of them were pre-ACLF,with a miss rate of 3.4%(missed/total,4/117).Conclusions:AD patients with≤1 organ dysfunction had a significantly lower risk of developing ACLF within 28 days of admission and could be safely ruled out with a pre-ACLF miss rate of<5%. | Xiaoting Tang Hai Li Guohong Deng Xin Zheng Xianbo Wang Yan Huang Yanhang Gao Zhongji Meng Zhiping Qian Feng Liu Xiaobo Lu Yu Shi Beiling Li Wenyi Gu Xiaomei Xiang Yan Xiong Yixin Hou Jun Chen Na Gao Sen Luo Liujuan Ji Jing Li Rongjiong Zheng Haotang Ren Jinjun Chen | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 1 |
| 13 | Optimization of Coenzyme Q10Production Procedure from Rhodobacter sphaeroides Overexpressing UbiE显示文摘In the present study,single factors including inoculation amount,fermentation temperature,fermentation duration and ratio of fermentation medium volume to total flask volume were optimized for enhancing the production of coenzyme Q10 from genetic engineered Rhodobacter sphaeroides overexpressing UbiE.The experimental results suggested that optimal single factors were: inoculation amount 2%,fermentation temperature 30 ℃,fermentation duration 48 h,and fermentation medium volume to total flask volume 80%.The present study will promote the large scale production of CoQ10 from microorganisms. | Kuo TANG Zhiping ZHAO Li ZHANG Zhenhui KANG | 2019 | Agricultural Biotechnology2019，8，5： | 1 |
| 14 | Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex显示文摘 | Huang Ying Wu Zhiping Riwanto Meliana Gao Shengqiang Levison Bruce S Gu Xiaodong Fu Xiaoming Wagner Matthew A Besler Christian Gerstenecker Gary Zhang Renliang Li Xin-Min DiDonato Anthony J Gogonea Valentin Tang W H Wilson Smith Jonathan D | 2013 | Journal of Clinical Investigation2013，，9： | 1 |
| 15 | Three-Dimensional DEM Theory and Its Application to Impact Mechanics显示文摘 | TANG Zhiping | | 0，，06： | 1 |
| 16 | Quasicrystals in as-cast Mg-Zn-RE alloys显示文摘 | LUO ZHIPING ZHANG SHAOQING TANG YALI | 1993 | Scripta Metall Mate1993，28，： | 1 |
| 17 | On the stable quasicrystals in slowly cooled Mg-Zn-Y alloys显示文摘 | LUO ZHIPING ZHANG SHAOQING TANG YALI | 1995 | Scripta Metall Mate1995，32，9： | 1 |
| 18 | A Study of Subject Service in Chinese Academic Libraries显示文摘 | Tang Yingqi Xia Zhiping | 2010 | CALA Occasional Pa- per Series2010，，7： | 1 |
| 19 | Cardioprotection of 17β-estradiol against hypoxia/reoxygenation in cardiomyocytes is partly through up-regulation of CRH receptor type 2显示文摘 | Binhai Cong Yongjun Xu Hui Sheng Xiaoyan Zhu Long Wang Wei Zhao Zhiping Tang Jianqiang Lu Xin Ni | 2014 | Molecular and Cellular Endocrinology2014，，1： | 1 |
| 20 | Investigation of the dynamic stability of microgfid显示文摘 | TANG Xisheng DENG Wei QI Zhiping | 2014 | IEEE Transactionson Power Electronics2014，29，2： | 1 |
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