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| 1 | Photo-curing 3D printing technique and its challenges显示文摘In recent ten years,3D printing technology has been developed rapidly.As an advanced technology,3D printing has been used to fabricate complex and high-precision objects in many fields.3D printing has several technologies.Among these technologies,photo-curing 3D printing was the earliest and most mature technology.In 1988,the first 3D printing machine which was based on photo-curing and called Stereo lithography Appearance(SLA)technology was produced by 3D system Corp.After 30 years of development,many new technologies based on photocuring mechanism emerged.Based on the different principle of pattern formation and character of printing technology,numerous photocuring 3D printing techniques,such as SLA,DLP,LCD,CLIP,MJP,twophoton 3D printing,holographic 3D printing and so on,have been developed.Photo-curing 3D printing has many advantages,such as high precision,smooth surface of printing objects,rapid printing speed and so on.Here,we would introduce five industrial photocuring 3D printing technologies,which are SLA,DLP,LCD,CLIP and MJP.The characters of the materials and the progress of the application of the technique in the biomedical field is also overviewed.At last,the difficulties and challenges of photo-curing 3D printing are also discussed. | Haoyuan Quan Ting Zhang Hang Xu Shen Luo Jun Nie Xiaoqun Zhu | 2020 | Bioactive Materials2020，5，1： | 33 |
| 2 | The apricot(Prunus armeniaca L.)genome elucidates Rosaceae evolution and beta-carotenoid synthesis显示文摘Apricots,scientifically known as Prunus armeniaca L,are drupes that resemble and are closely related to peaches or plums.As one of the top consumed fruits,apricots are widely grown worldwide except in Antarctica.A high-quality reference genome for apricot is still unavailable,which has become a handicap that has dramatically limited the elucidation of the associations of phenotypes with the genetic background,evolutionary diversity,and population diversity in apricot.DNA from P.armeniaca was used to generate a standard,size-selected library with an average DNA fragment size of~20 kb.The library was run on Sequel SMRT Cells,generating a total of 16.54 Gb of PacBio subreads(N50=13.55 kb).The high-quality P.armeniaca reference genome presented here was assembled using long-read single-molecule sequencing at approximately 70×coverage and 171×Illumina reads(40.46 Gb),combined with a genetic map for chromosome scaffolding.The assembled genome size was 221.9 Mb,with a contig NG50 size of 1.02 Mb.Scaffolds covering 92.88%of the assembled genome were anchored on eight chromosomes.Benchmarking Universal Single-Copy Orthologs analysis showed 98.0%complete genes.We predicted 30,436 protein-coding genes,and 38.28%of the genome was predicted to be repetitive.We found 981 contracted gene families,1324 expanded gene families and 2300 apricot-specific genes.The differentially expressed gene(DEG)analysis indicated that a change in the expression of the 9-cis-epoxycarotenoid dioxygenase(NCED)gene but not lycopene beta-cyclase(LcyB)gene results in a lowβ-carotenoid content in the white cultivar“Dabaixing”.This complete and highly contiguous P.armeniaca reference genome will be of help for future studies of resistance to plum pox virus(PPV)and the identification and characterization of important agronomic genes and breeding strategies in apricot. | Fengchao Jiang Junhuan Zhang Sen Wang Li Yang Yingfeng Luo Shenghan Gao Meiling Zhang Shuangyang Wu Songnian Hu Haoyuan Sun Yuzhu Wang | 2019 | Horticulture Research2019，6，1： | 9 |
| 3 | Real-Time Position and Attitude Estimation for Homing and Docking of an Autonomous Underwater Vehicle Based on Bionic Polarized Optical Guidance显示文摘As an important tool for marine exploration, the autonomous underwater vehicle(AUV) must home in and dock at a docking station(DS) to be recharged, repaired, or to exchange information at set intervals. However, the complex and hostile underwater environment makes this process challenging. This study proposes a real-time method based on polarized optical guidance for determining the position and attitude of the AUV relative to its DS. Four polarized artificial underwater landmarks are positioned at the DS, which are recognized by the AUV vision system. Compared with light intensity, the polarization of a light beam is known to be better maintained at greater propagation distances, especially in underwater environments. The proposed method, which is inspired by the ability of marine animals to communicate, calculates the pose parameters in less than 10 ms without any other navigational information. The simulation results reveal that the angle errors are small and the position errors are no more than 0.116 m within 100 m in the coastal ocean. The results of underwater experiments further demonstrate the feasibility of the proposed method, which extends the operating distance of the AUV beyond what is currently possible while maintaining the precision of traditional optical guidance. | CHENG Haoyuan CHU Jinkui ZHANG Ran GUI Xinyuan TIAN Lianbiao | 2020 | Journal of Ocean University of China2020，19，5： | 6 |
| 4 | Famitinib in combination with concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma: a phase 1, open-label, dose-escalation Study显示文摘Background:Famitinib is a tyrosine kinase inhibitor against multiple targets,including vascular endothelial growth factor receptor 2/3,platelet-derived growth factor receptor,and stem cell factor receptor(c-kit).Previous studies have demonstrated anti-tumour activities of famitinib against a wide variety of advanced-stage solid cancers.We aimed to determine the safety and efficacy of famitinib with concurrent chemoradiotherapy(CCRT)in patients with locoregionally advanced nasopharyngeal carcinoma(NPC).We also evaluated the feasibility of contrast-enhanced ultrasound(D-CEUS)as a predictor of early tumour response to famitinib and to correlate functional parameters with clinical efficacy.Methods:The trial was conducted in subjects with stage III or IVa-b NPC using a 3+3 design of escalating fami-tinib doses.Briefly,subjects received 2 weeks of famitinib monotherapy followed by 7 weeks of famitinib plus CCRT.D-CEUS of the neck lymph nodes was performed at day 0,8 and 15 after famitinib was administered before starting concurrent chemoradiotherapy.End points included safety,tolerability and anti-tumour activity.Results:Twenty patients were enrolled(six each for 12.5,16.5 and 20 mg and two for 25 mg).Two patients in the 25 mg cohort developed dose-limiting toxicities,including grade 4 thrombocytopenia and grade 3 hypertension.The most common grade 3/4 adverse events were leukopenia,neutropenia and radiation mucositis.D-CEUS tests showed that more than 60%of patients achieved a perfusion parameter response after 2 weeks taking famitinib alone,and the parameter response was associated with disease improvement.In the famitinib monotherapy stage,three patients(15%)showed partial responses.The complete response rate was 65%at the completion of treatment and 95%3 months after the treatment ended.After a median follow-up of 44 months,the 3-year progression-free survival(PFS)and distant metastasis-free survival were 70%and 75%,respectively.Subjects with a decrease of perfusion parameter response,such as peak intensity decreased at least 30%after 1 week of famitinib treatment,had higher 3-year PFS(90.9%vs.44.4%,95%CI 73.7%-100%vs.11.9%-76.9%,P<0.001)than those with an increase or a reduction of less than 30%.Conclusions:The recommended famitinib dose for phase II trial is 20 mg with CCRT for patients with local advanced NPC.D-CEUS is a reliable and early measure of efficacy for famitinib therapies.Further investigation is required to confirm the effects of famitinib plus chemoradiotherapy. | Qiuyan Chen Linquan Tang Na Liu Feng Han Ling Guo Shanshan Guo Jianwei Wang Huai Liu Yanfang Ye Lu Zhang Liting Liu Pan Wang Yingqin Li Qingmei He Xiaoqun Yang Qingnan Tang Yang Li YuJing Liang XueSong Sun Chuanmiao Xie Yunxian Mo Ying Guo Rui Sun Haoyuan Mo Kajia Cao Xiang Guo Musheng Zeng Haiqiang Mai Jun Ma | 2018 | Cancer Communications2018，38，1： | 6 |
| 5 | Study of lithium/polypyrrole secondary batteries with Lithium as cathode and polypyrrole anode显示文摘Lithium/polypyrrole (Li/PPy) batteries were fabricated using lithium sheet as cathode, PPy as anode, microporous membrane polypropylene/polyethylene/polypropylene (PP/PE/PP) composite as separator and LiPF6/ethylene carbonate-dimethyl carbonate-methyl ethyl carbonate (EC-DMC-EMC) as electrolyte. Polypyrrole was prepared by chemical polymerization. Certain fundamental electrochemical performances were investigated. Properties of the batteries were characterized and tested by SEM, galvanostatic charge/discharge tests, cyclic voltammetry (CV), and a.c. impedance spectroscopy. The influences of separator, morphology, and conductivity of PPy anode, cold-molded pressure, and electric current on the performances of the batteries were studied. Using PP/PE/PP membranes as separator, the battery showed good storage stability and cycling property. The conductivity of materials rather than morphology affected the behavior of the battery. The higher the conductivity, the better performances the cells had. Proper cold-molded pressure 20 MPa of the anode pellet would make the properties of the cells good and the fitted charge/discharge current was 0.1 mA. The cells showed excellent performance with 97%-100% coulombic efficiency. The highest discharge capacity of 95.2 mAh/g was obtained. | REN Li WANG Lixin AN Haoyuan ZHANG Fuqiang | 2007 | Rare Metals2007，26，6： | 6 |
| 6 | A state-of-the-art review of asphalt pavement surface texture and its measurement techniques显示文摘To understand the research status of asphalt pavement texture,the related achievements and progress of pavement surface texture were systematically sorted out from three aspects:the characterization of pavement surface texture,the texture measurement and evaluation,and the relationship between texture and the skid resistance.Based on the statistical geometric characteristics,the spectral characteristics,the fractal characteristics and the multifractal characteristics,the characteristics of pavement texture were discussed.The test methods of pavement texture were divided into two categories:direct measurement methods and indirect measurement methods.The advantages and disadvantages of each measurement method were summarized.The effects of macro-texture and micro-texture on asphalt pavement were discussed,respectively.The relationship between texture and skid resistance was studied.This review shows that multifractal theory should be further studied from the aspect of road engineering.High-precision non-contact integrated detection technology should be further studied to meet the needs of complex testing environments.The method of finite element numerical simulation has potential for the analysis of pavement skid resistance.In addition,methods such as big data analysis,neural network,and deep learning should be studied to achieve the intelligent perception and management of the whole state of skid resistance prediction. | Siyu Chen Xiyin Liu Haoyuan Luo Jiangmiao Yu Fuda Chen Yang Zhang Tao Ma Xiaoming Huang | 2022 | Journal of Road Engineering2022，2，2： | 3 |
| 7 | Visualization Experiment and Numerical Analysis of Cavitation Flow Characteristics in Diesel Fuel Injector Control Valve with Different Structure Design显示文摘Increasing the injection pressure has been proven an effective method to enhance performance and reduce pollutant of diesel engine.With the increase of the injection pressure,the cavitation damage problem inside common rail fuel injector is more significant,which has direct influences on reliability of diesel engine.While the most studies so far have focused on cavitation occurred in injector nozzle and its atomization characteristics,few researchers studied the cavitation phenomenon in fuel injector control valve.But due to the complexity of flow field and difficulty of experiment,the cavitation in control valve could not be fully described by existing theories.In this paper,the two-dimensional visualization experiment and numerical simulation of control valve was implemented to acquire the image of cavitation intuitively and validate the simulation method and model.Then a new structure design of control valve named convergent model was presented for comparison.The origin model and convergent model with different valve lifts were simulated in three dimensions.The results showed that the sheet cavitation occurred at the surface of seal cone and steel ball then turned to cloud cavitation in downstream area.The intensity of cavitation increased with the increase of valve lift.Convergent model could efficiently reduce the cavitation intensity near the seal area.This research could provide references for engineering optimization design of control valve. | MA Haoyuan ZHANG Tong AN Qingsong TAO Yuhao XU Yue | 2021 | Journal of Thermal Science2021，30，1： | 3 |
| 8 | Theoretical prediction for effective properties and progressive failure of textile composites:a generalized multi-scale approach显示文摘A generalized analytical model is developed to predict progressive failure behavior of several types of textile composites,including plain weave composites,twill weave composites,two-dimensional tri-axially braided composites and warpreinforced 2.5-dimensional braided composites.In this model,the unit cell(UC)of composite is firstly identified and reconstructed into a refined lamina structure with multiple equivalent lamina elements(ELEs)based on apt geometrical approximation and assumptions.Secondly,two-way coupled stress-strain responses within the UC(macro-scale)and ELE(meso-scale)are established through a universal series-parallel model(SPM).Finally,a progressive damage model,which consists of damage initiation criteria and a stiffness evolution strategy,is employed to predict damage behavior of the ELE.The analytical results including mechanical properties and progressive failure process are validated against the existing numerical and experimental ones in literature.The validated analytical model is then used to study the effects of global fiber volume fraction,braided angle,shear failure coefficient and selected failure criteria on stiffness,strength and failure process.The present results demonstrate the efficiency and generic capability of the present analytical model for predicting the mechanical responses of a range of textile composites. | Haoyuan Dang Peng Liu Yinxiao Zhang Zhenqiang Zhao Liyong Tong Chao Zhang Yulong Li | 2021 | Acta Mechanica Sinica2021，37，8： | 3 |
| 9 | Substituent position effect of Co porphyrin on oxygen electrocatalysis显示文摘Substituent effect of metal porphyrin molecular catalysts plays a crucial role in determining the catalytic activity of oxygen electrocatalysis.Herein,substituent position effect of Co porphyrins on oxygen electrocatalysis,including the oxygen reduction reaction(ORR)and the oxygen evolution reaction(OER),was investigated.Two Co porphyrins,namely 2,4,6-OMe-CoP and 3,4,5-OMe-CoP,were selected as the research objects.The ORR and OER performance was evaluated by drop-coating molecular catalysts on carbon nanotubes(CNTs).The resulted 3,4,5-OMe-CoP/CNT exhibited high bifunctional electrocatalytic activities and better long-term stability for both ORR and OER than 2,4,6-OMe-CoP/CNT.Furthermore,when applied in the Zn-air battery,3,4,5-OMe-CoP/CNT exhibited comparable performance to that with precious metal-based materials.The enhanced catalytic activity may be attributed to the improved charge transfer rate,mass transfer and hydrophilicity.This work provides an effective strategy to further enhance catalytic activity by introducing substituent position effect,which is of great importance for developing more efficient energy-related electrocatalysts. | Haoyuan Lv Hongbo Guo Kai Guo Haitao Lei Wei Zhang Haoquan Zheng Zuozhong Liang Rui Cao | 2021 | Chinese Chemical Letters2021，32，9： | 2 |
| 10 | Taking the pulse of COVID-19:a spatiotemporal perspective显示文摘The sudden outbreak of the Coronavirus disease(COVID-19)swept across the world in early 2020,triggering the lockdowns of several billion people across many countries,including China,Spain,India,the U.K.,Italy,France,Germany,Brazil,Russia,and the U.S.The transmission of the virus accelerated rapidly with the most confirmed cases in the U.S.,India,Russia,and Brazil.In response to this national and global emergency,the NSF Spatiotemporal Innovation Center brought together a taskforce of international researchers and assembled implementation strategies to rapidly respond to this crisis,for supporting research,saving lives,and protecting the health of global citizens.This perspective paper presents our collective view on the global health emergency and our effort in collecting,analyzing,and sharing relevant data on global policy and government responses,human mobility,environmental impact,socioeconomical impact;in developing research capabilities and mitigation measures with global scientists,promoting collaborative research on outbreak dynamics,and reflecting on the dynamic responses from human societies. | Chaowei Yang Dexuan Sha Qian Liu Yun Li Hai Lan Weihe Wendy Guan Tao Hu Zhenlong Li Zhiran Zhang John Hoot Thompson Zifu Wang David Wong Shiyang Ruan Manzhu Yu Douglas Richardson Luyao Zhang Ruizhi Hou You Zhoua Cheng Zhong Yifei Tian Fayez Beaini Kyla Carte Colin Flynn Wei Liu Dieter Pfoser Shuming Bao Mei Li Haoyuan Zhang Chunbo Liu Jie Jiang Shihong Du Liang Zhao Mingyue Lu Lin Li Huan Zhou Andrew Ding | 2020 | International Journal of Digital Earth2020，13，10： | 2 |
| 11 | Wearable and flexible electrochemical sensors for sweat analysis:a review显示文摘Flexible wearable sweat sensors allow continuous,real-time,noninvasive detection of sweat analytes,provide insight into human physiology at the molecular level,and have received significant attention for their promising applications in personalized health monitoring.Electrochemical sensors are the best choice for wearable sweat sensors due to their high performance,low cost,miniaturization,and wide applicability.Recent developments in soft microfluidics,multiplexed biosensing,energy harvesting devices,and materials have advanced the compatibility of wearable electrochemical sweat-sensing platforms.In this review,we summarize the potential of sweat for medical detection and methods for sweat stimulation and collection.This paper provides an overview of the components of wearable sweat sensors and recent developments in materials and power supply technologies and highlights some typical sensing platforms for different types of analytes.Finally,the paper ends with a discussion of the challenges and a view of the prospective development of this exciting field. | Fupeng Gao Chunxiu Liu Lichao Zhang Tiezhu Liu Zheng Wang Zixuan Song Haoyuan Cai Zhen Fang Jiamin Chen Junbo Wang Mengdi Han Jun Wang Kai Lin Ruoyong Wang Mingxiao Li Qian Mei Xibo Ma Shuli Liang Guangyang Gou Ning Xue | 2023 | Microsystems & Nanoengineering2023，9，1： | 2 |
| 12 | Petrological and mineralogical characterizations and chemical composition of coal ashes from power plants in Yanzhou mining district, China显示文摘 | Liu Guijian Zhang Haoyuan Gao Lianfen | 2004 | Fuel Processing Technology2004，，15： | 1 |
| 13 | Experimental and theoretical study of the charge transport property of 4,4′-N,N′-dicarbazole-biphenyl显示文摘The hole and electron mobilities of the amorphous films of the organic semiconductor 4,4′-N,N′-dicarbazole-biphenyl (CBP) at different electric fields were measured through the time of flight (TOF) method. Based on its crystalline structure, the hole and electron mobilities of CBP were calculated. A detailed comparison between experimental and theoretical results is necessary for further understanding its charge transport properties. In order to do this, charge mobilities at zero electric field, μ(0), were deduced from experimental data as a link between experimental and theoretical data. It was found that the electron transport of CBP is less affected by traps compared with its hole transport. This unusual phenomenon can be understood through the distributions of frontier molecular orbitals. We showed that designing materials with frontier molecular orbitals localized at the center of the molecule has the potency to reduce the influence of traps on charge transport and provide new insights into designing high mobility charge transport materials. | LI HaoYuan CHEN Liang QIAO Juan DUAN Lian ZHANG DeQiang DONG GuiFang WANG LiDuo QIU Yong | 2012 | Science China Chemistry2012，55，11： | 1 |
| 14 | Petrological and mineralogical characterizations and chemical composition of coal ashes from power plants in Yanzhou mining district,China显示文摘 | Haoyuan Zhang Lianfen Gao | 2004 | Fuel Processing Technology2004，85，： | 1 |
| 15 | The first local case of mpox caused by an imported case in the Chinese mainland显示文摘Monkeypox (mpox) is a zoonotic disease caused by the mpox virus (MPXV) that has been primarily limited to Central and West African nations since its discovery. The recent spread of the West African lineage of MPXV in historically unaffected countries has raised concerns for global public health. Despite a significant decrease in global mpox cases, there is still a risk of a global resurgence. This study reports the first local case of mpox caused by an imported case in the Chinese mainland. Polymerase chain reaction (PCR) diagnosed the two cases, and the viral genomes were obtained by next-generation sequencing. Genomic analysis revealed that the two strains shared an identical genome sequence and belonged to the B.1.3 branch of the West African lineage, which is the first local case of mpox caused by an imported case in the Chinese mainland, highlighting the potential threat of mpox in China and the immediate need for adequate surveillance measures. | Daitao Zhang Xiao Qi Fu Li Yanhui Chu Ke Wu Jia Li Xin Meng Xiangfeng Dou Zhenyong Ren Haoyuan Jin Shuang Li Yulan Sun Yanwei Chen Renqing Li Dan Li Weihong Li Yang Yang Yang Pan Wenjie Tan Quanyi Wang | 2023 | Biosafety and Health2023，5，4： | 1 |
| 16 | High‐Efficiency Fluorescent Organic Light‐Emitting Devices Using Sensitizing Hosts with a Small Singlet–Triplet Exchange Energy显示文摘 | Dongdong Zhang Lian Duan Chen Li Yilang Li Haoyuan Li Deqiang Zhang Yong Qiu | 2014 | Adv Mater2014，，29： | 1 |
| 17 | Towards High Efficiency and Low Roll‐Off Orange Electrophosphorescent Devices by Fine Tuning Singlet and Triplet Energies of Bipolar Hosts Based on Indolocarbazole/1, 3, 5‐Triazine Hybrids显示文摘 | Dongdong Zhang Lian Duan Yilang Li Haoyuan Li Zhengyang Bin Deqiang Zhang Juan Qiao Guifang Dong Liduo Wang Yong Qiu | 2014 | Adv Funct Mater2014，，23： | 1 |
| 18 | Assessing the effect of climate change on reference evapotranspiration in China显示文摘 | Zhang Dan Liu Xiaomang Hong Haoyuan | 2013 | Stoch Environ Res Risk Assess2013，27，8： | 1 |
| 19 | Detecting Abnormal Start-Ups, Unusual Resource Consumptions of the Smart Phone: A Deep Learning Approach显示文摘The temporal distance between events conveys information essential for many time series tasks such as speech recognition and rhythm detection.While traditional models such as hidden Markov models(HMMs)and discrete symbolic grammars tend to discard such information,recurrent neural networks(RNNs)can in principle learn to make use of it.As an advanced variant of RNNs.long short-term memory(LSTM)has an alternative(arguably better)mechanism for bridging long time lags.We propose a couple of deep neural network-based models to detect abnormal start-ups,unusual CPU and memory consumptions of the application processes running on smart phones.Experiment results showed that the proposed neural networks achieve remarkable performance at some reasonable computational cost.The speed advantage of neural networks makes them even more competitive for the applications requiring real-time response,offering the proposed models the potential for practical systems. | ZHENG Xiaoqing LU Yaping PENG Haoyuan FENG Jiangtao ZHOU Yi JIANG Min MA Li ZHANG Ji JI Jie | 2019 | ZTE Communications2019，17，2： | 0 |
| 20 | Intermetallic CuAu nanoalloy for stable electrochemical CO_(2) reduction显示文摘Copper is one of the most efficient catalysts widely investigated in electrochemical CO_(2) reduction, however, the further development of copper-based catalysts is constrained by severe stability problems. In this work, we developed a method for the synthesis of highly ordered Cu Au intermetallic nanoalloys(o-CuAu) under mild conditions(< 250℃), which can convert carbon dioxide to carbon monoxide with high selectivity and can operate stably for 160 h without current decay. The improved stability is believed to be due to the increased mixing enthalpy and stronger atomic interactions between Cu and Au atoms in the intermetallic nanoalloy. In addition, XPS results, Tafel slope and in situ IR spectroscopy demonstrate that high valence gold atoms on o-CuAu surface promote the reduction of CO_(2). In contrast, the disordered CuAu nanoalloy(d-CuAu) underwent atomic rearrangement to form a Cu-rich structure on the surface, leading to reduced stability. These findings may provide insight into the rational design of stable CO_(2) RR electrocatalysts through proper structural engineering. | Siyu Kuang Minglu Li Xiaoyi Chen Haoyuan Chi Jianlong Lin Zheng Hu Shi Hu Sheng Zhang Xinbin Ma | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
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