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| 1 | Clinical diagnosis and treatment of alpha-fetoprotein-negative small hepatic lesions显示文摘Objective: We examined 103 cases over the last five years and discussed diagnosis and treatment of alpha- fetoprotein (AFP)-negative small hepatic lesions. Background: Small hepatic lesions (less than 2 cm in diameter) usually have no typical imaging characteristics and therefore are difficult to diagnose, especially when AFP tests provide a negative result. Methods: A total of 103 patients with AFP-negative small hepatic lesions from January 2003 to December 2008 were retrospectively reviewed. Differential diagnosis was performed by digital subtraction angiography (DSA), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), contrast-enhanced ultrasound (CEUS), or positron emission tomography-computed tomography (PET-CT) based on the multiplicity of lesions. Ninety-four patients with suspected cancers underwent partial hepatectomy. Clinical data were collected from hospital records and follow-up questionnaires. Results: Hepatocellular carcinoma (HCC) diagnostic sensitivity of DSA, DCE-MRI, CEUS and PET-CT was 88.2%, 93.9%, 88.9% and 88.9%, respectively. The surgery-related complication rate was 6.4%. Prognosis was good, with 1- and 3-year survival rates of 98.8% and 76.1%, respectively. Conclusions: DSA, DCE-MRI, CEUS and PET-CT are valuable for diagnosis of small hepatic lesions. Partial hepatectomy is a preferred surgical procedure. Surgery for small liver cancers usually has little risk and good prognosis, therefore it can be actively applied in suspected HCC cases. | Yiyao Xu Xin Lu Yilei Mao Xinting Sang Haitao Zhao Shunda Du Haifeng Xu Yongliang Sun Huayu Yang Tianyi Chi Zhiying Yang Shouxian Zhong Jiefu Huang | 2013 | Chinese Journal of Cancer Research2013，25，4： | 6 |
| 2 | Nitrogen-doped graphene:Synthesis,characterizations and energy applications显示文摘Nitrogen-doped(N-doped) graphene has attracted increasing attentions because of the significantly enhanced properties in physic, chemistry, biology and material science, as compared with those of pristine graphene. By date, N-doped graphene has opened up an exciting new field in the science and technology of two-dimensional materials. From the viewpoints of chemistry and materials, this article presents an overview on the recent progress of N-doped graphene, including the typical synthesis methods, characterization techniques, and various applications in energy fields. The challenges and perspective of Ndoped graphene are also discussed. We expect that this review will provide new insights into the further development and practical applications of N-doped graphene. | Haifeng Xu Lianbo Ma Zhong Jin | 2018 | Journal of Energy Chemistry2018，27，1： | 4 |
| 3 | Gut health benefit and application of postbiotics in animal production显示文摘Gut homeostasis is of importance to host health and imbalance of the gut usually leads to disorders or diseases for both human and animal.Postbiotics have been applied in manipulating of gut health,and utilization of postbiotics threads new lights into the host health.Compared with the application of probiotics,the characteristics such as stability and safety of postbiotics make it a potential alternative to probiotics.Studies have reported the beneficial effects of components derived from postbiotics,mainly through the mechanisms including inhibition of pathogens,strengthen gut barrier,and/or regulation of immunity of the host.In this review,we summarized the characteristics of postbiotics,main compounds of postbiotics,potential mechanisms in gut health,and their application in animal production. | Yifan Zhong Shanshan Wang Hanqiu Di Zhaoxi Deng Jianxin Liu Haifeng Wang | 2022 | Journal of Animal Science and Biotechnology2022，13，4： | 3 |
| 4 | Aberrant expression of BDNF might serve as a candidate target for cocaine- induced psychosis: insights from bioinformatics analysis and microarray validation显示文摘Background Cocaine use disorder(CUD)and associated psychosis are major public health issues worldwide,along with high relapse outcome and limited treatment options.Exploring the molecular mechanisms underlying cocaine-induced psychosis(CIP)could supply integrated insights for understanding the pathogenic mechanism and potential novel therapeutic targets.Aims The aim of the study was to explore common alterations of CUD-schizophrenia target genes and identify core risk genes contributing to CIP through data mining and network pharmacology approach.Methods Target genes of CUD were obtained from GeneCards,Comparative Toxicogenomics Database,Swiss Target Prediction platform and PubChem.Schizophrenia-related target genes were derived from DisGeNET,GeneCards,MalaCards and Online Mendelian Inheritance in Man databases.Then,the overlap genes of these two sets were regarded as risk genes contributing to CIP.Based on these CUD-schizophrenia target genes,functional annotation and pathway analysis were performed using the clusterProfiler package in R.Protein-protein interaction network construction and module detection were performed based on the Search Tool for the Retrieval of Interacting Genes(STRING)database and Cytoscape software.Gene expression datasets GSE54839 and GSE93577 were applied for data validation and diagnostic capacity evaluation of interested hub genes.Results A total of 165 CUD-schizophrenia target genes were obtained.These genes were mainly contributing to chemical synaptic transmission,neuropeptide hormone activity,postsynaptic membrane and neuroactive ligand-receptor interaction pathway.Network analysis and validation analysis indicated that BDNF might serve as an important risk gene in mediating CIP.Conclusions This study generates a holistic view of CIP and provides a basis for the identification of potential CUD-schizophrenia target genes involved in the development of CIP.The abnormal expression of BDNF would be a candidate therapeutic target underlying the pathogenesis of CUD and associated CIP. | Youwei Zhu Yan Zhao Xiaomin Xu Hang Su Xiaotong Li Na Zhong Haifeng Jiang Jiang Du Min Zhao | 2021 | General Psychiatry2021，34，5： | 2 |
| 5 | Atomically precise metal-chalcogenide semiconductor molecular nanoclusters with high dispersibility:Designed synthesis and intracluster photocarrier dynamics显示文摘A comprehensive understanding of excited-state dynamics of semiconductor quantum dots or nanomaterials at the atomic or molecular level is of scientific importance.Pure inorganic(or non-covalently protected)seimiconductor molecular nanoclusters with atomically precise structure are contributive to establish accurate correlation of excited-state dynamics with their composition/structure,however,the related studies are almost blank because of unresolved solvent dispersion issue.Herein,we designedly created the largest discrete chalcogenide seimiconductor molecular nanoclusters(denoted P2-CuMSnS,M=In or/and Ga)with great dispersibility,and revealed an interesting intracluster“core–shell”charge transfer relaxation dynamics.A systematic red shift in absorption spectra with the gradual substitution of In by Ga was experimentally and computationally investigated,and femtosecond transient absorption measurements further manifested there were three ultrafast processes in excited-state dynamics of P2 nanoclusters with the corresponding amplitudes directed by composition variation.Current results hold the great promise of the solution-processible applications of semiconductor-NC-based quantum dots and facilitate the development of atomically precise nano-chemistry. | Jiaxu Zhang Chaochao Qin Yeshuang Zhong Xiang Wang Wei Wang Dandan Hu Xiaoshuang Liu Chaozhuang Xue Rui Zhou Lei Shen Yinglin Song Dingguo Xu Zhien Lin Jun Guo Haifeng Su Dong-Sheng Li Tao Wu | 2020 | Nano Research2020，13，10： | 2 |
| 6 | Study ofmalondialdehyde (MDA) content, superoxide dismutase (SOD) andglutathione peroxidase (GSH-Px) activities in chickens infected withavian infectious bronchitis virus显示文摘 | WANG Haifeng ZHONG Xiuhui SHI Wanyu | 2011 | African Journal of Biotechnology2011，10，45： | 1 |
| 7 | Flexible and Reusable Non-woven Fabric Photodetector Based on Polypyrrole/Crystal Violate Lactone for NIR Light Detection and Writing显示文摘Rapid NIR light detection and/or writing has drawn much attention,but their practical applications have been limited by obtaining such NIR photodetectors.To address this problem,we have developed a simple and versatile strategy to prepare a non-woven fabric photodetector.The blue non-woven fabric photodetector has been prepared by coating photo-thermochromic ink(including crystal violet lactone(CVL)as the thermo-sensitive dye,polypyrrole(PPy)nanospheres as the photothermal component and hydroxyethyl cellulose(HEC)as the polymer matrix)on white non-woven fabric.When the blue fabric photodetector is irradiated by NIR(808-nm as model,0.75 W cm^(−2))laser,the discoloration occurs in 35 s,and higher laser intensity confers more rapid discoloration.This discoloration results from the photothermal effect of PPy which confers the elevation of temperature(>50℃)and then converts CVL to its leuco form(colorless).When the laser is turned off,the temperature drops to below the transition temperature(<43℃),and then CVL reverts to its initial blue color.Moreover,different figures and images can be easily printed on the fabric photodetector by 808 nm laser,and then they can be erased automatically under ambient conditions,with excellent cycling stability.Therefore,this fabric photodetector may act as a new platform for rapid NIR light detection and writing. | Shuangping Yang Daniel K.Macharia Sharjeel Ahmed Bo Zhu Qiuping Zhong Haifeng Wang Zhigang Chen | 2020 | Advanced Fiber Materials2020，2，3： | 1 |
| 8 | Deformation Mechanisms of Carrara Marble Under Increasing Temperatures from 300℃ to 550℃显示文摘Deformation experiments of Carrara marble were conducted under increasing temperatures (temperatures 300℃ - 550℃, confining pressure 0. 5Mpa, strain - rate 5 × 10- 6 s-1 ). The experiments reveal that calcite rocks show different deformation behaviors and corresponding microstructural characteristics under different temperatures. By analyzing microstructural characteristics, preferred grain shape orientation variation of the primary rocks and deformed specimen, the deformation features of Carrara marble are summarized: twinning, fracturing dominates deformation of the rocks at temperatures between 300℃ and 450℃; dynamic recrystallization occurs in the temperature range of 450- 550℃; the brittle to crystalline plasticity transition deformation is observed at around 450℃, twinning and crystal - plastic deformation become dominant with further increasing temperature. | Ma Lijie Liu Junlai Li Haifeng Wang Xiaoyong Zhong Xinyong | 2000 | Global Geology2000，5，2： | 1 |
| 9 | A novel collector 2-ethyl-2-hexenoic hydroxamic acid:Flotation performance and adsorption mechanism to ilmenite显示文摘 | Xu Haifeng Zhong Hong Tang Qing | 2015 | Applied Surface Science2015，353，： | 1 |
| 10 | Expert consensus on the prevention and treatment of substance use and addictive behaviour-related disorders during the COVID-19 pandemic显示文摘In early 2020,the COVID-19 outbreak complicated the diagnosis,treatm ent and rehabilitation of patients with substance use disorders and increased the risks of substance abuse and addictive behaviours,such as online gaming disorders,in the general public.Substance use disorder is a chronic recurrent brain disease characterised by strong cravings,high recurrence rates,and a high proportion of comorbidity of mental and physical disorders.1 Therefore,regular long-term therapeutic interventions are critical to preventing dm g relapses while maintaining withdrawal. | Jiang Du Ni Fan Min Zhao Wei Hao Tieqiao Liu Lin Lu Jie Shi Haifeng Jiang Na Zhong Xiaochang Lan Shichao Xu Hongxian Chen Xiaojun Xiang Xuyi Wang Hongqiang Sun Bing Li Yu-Ping Ning Jing Li Wanjun Guo Yajuan Niu Lixia Sheng Yi Li Xuebin Liu Xuhui Zhou Mincai Qian Wenhua Zhou Ruiling Zhang Hongxing Hu Yan Xia Zhonghua Su Ruimin Zhang Mei Yang Fen Liu Wei Yuan | 2020 | General Psychiatry2020，33，4： | 1 |
| 11 | Enhanced mixing state of black carbon with nitrate in single particles during haze periods in Zhengzhou, China显示文摘Black carbon(BC)plays an important role in air quality and climate change,which is closely associated with its mixing state and chemical compositions.In this work the mixing state of BC-containing single particles was investigated to explore the evolution process of ambient BC particles using a single particle aerosol mass spectrometer(SPAMS)in March 2018 in Zhengzhou,China.The BC-containing particles accounted for 61.4%of total detected ambient single particles and were classified into five types including BC-nitrate(BC-N,52.3%)as the most abundant species,followed by BC-nitrate-sulfate(BC-NS,22.4%),BCOC(16.8%),BC-fresh(BC-F,4.5%)and BC-sulfate particles(BC-S,4.0%).With enhancement of the ambient nitrate concentration,the relative peak area(RPA)of nitrate in BC-N and BC–NS particles both increased,yet only the number fraction(N_(f))of BC–N particles increased while the N_(f) of BC-NS particles decreased,suggesting that the enhanced mixing state of BC with nitrate was mainly due to the increase in the ambient nitrate mass concentration.In addition,the Nfof BC-N decreased from 65.3%to 28.4%as the absorbing Angstrom exponents(AAE)of e BC increased from 0.75 to 1.45,which indicated the reduction of light absorption ability of aged BC particles with the enhanced formation of BC-N particles.The results of this work indicated a change in the mixing state of BC particles due to the dominance of nitrate in PM_(2.5),which also influenced the optical properties of aged BC particles. | Qianni Zhou Chunlei Cheng Suxia Yang Minghao Yuan Jingjing Meng Haifeng Gong Qien Zhong Yao Zhang Yutong Xie Zhen Zhou Mei Li | 2022 | Journal of Environmental Sciences2022，34，1： | 0 |
| 12 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 13 | L.reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide显示文摘Background:This study investigated the protective effects of L.reuteri ZJ617 on intestinal and liver injury and the underlying mechanisms in modulating inflammatory,autophagy,and apoptosis signaling pathways in a piglet challenged with lipopolysaccharide(LPS).Methods:Duroc×Landrace×Large White piglets were assigned to 3 groups(n=6/group):control(CON)and LPS groups received oral phosphate-buffered saline for 2 weeks before intraperitoneal injection(i.p.)of physiological saline or LPS(25μg/kg body weight),respectively,while the ZJ617+LPS group was orally inoculated with ZJ617 for 2 weeks before i.p.of LPS.Piglets were sacrificed 4 h after LPS injection to determine intestinal integrity,serum biochemical parameters,inflammatory signaling involved in molecular and liver injury pathways.Results:Compared with controls,LPS stimulation significantly increased intestinal phosphorylated-p38 MAPK,phosphorylated-ERK and JNK protein levels and decreased IκBαprotein expression,while serum LPS,TNF-α,and IL-6 concentrations(P<0.05)increased.ZJ617 pretreatment significantly countered the effects induced by LPS alone,with the exception of p-JNK protein levels.Compared with controls,LPS stimulation significantly increased LC3,Atg5,and Beclin-1 protein expression(P<0.05)but decreased ZO-1,claudin-3,and occludin protein expression(P<0.05)and increased serum DAO and D-xylose levels,effects that were all countered by ZJ617 pretreatment.LPS induced significantly higher hepatic LC3,Atg5,Beclin-1,SOD-2,and Bax protein expression(P<0.05)and lower hepatic total bile acid(TBA)levels(P<0.05)compared with controls.ZJ617 pretreatment significantly decreased hepatic Beclin-1,SOD2,and Bax protein expression(P<0.05)and showed a tendency to decrease hepatic TBA(P=0.0743)induced by LPS treatment.Pretreatment of ZJ617 before LPS injection induced the production of 5 significant metabolites in the intestinal contents:capric acid,isoleucine 1TMS,glycerol-1-phosphate byproduct,linoleic acid,alanine-alanine(P<0.05).Conclusions:These results demonstrated that ZJ617 pretreatment alleviated LPS-induced intestinal tight junction protein destruction,and intestinal and hepatic inflammatory and autophagy signal activation in the piglets. | Tao Zhu Jiangdi Mao Yifan Zhong Congxiang Huang Zhaoxi Deng Yanjun Cui Jianxin Liu Haifeng Wang | 2022 | Journal of Animal Science and Biotechnology2022，13，2： | 0 |
| 14 | Interharmonic Analysis Model of Photovoltaic Grid-connected System with Extended Dynamic Phasors显示文摘The interactions between randomly fluctuating power outputs from photovoltaic(PV) at the DC side and background voltage distortions at the AC side could generate interharmonics in the PV grid-connected system(PVGS). There is no universal method that can reveal the transmission mechanism of interharmonics and realize accurate calculation in different scenarios where interharmonics exist in the PVGS. Therefore, extended dynamic phasors(EDPs) and EDP sequence components(EDPSCs) are employed in the interharmonic analysis of the PVGS. First, the dynamic phasors(DPs) and dynamic phasor sequence components(DPSCs) are extended into EDPs and EDPSCs by selecting a suitable fundamental frequency other than the power frequency. Second, an interharmonic analysis model of the PVGS is formulated as a set of state space equations. Third, with the decoupling characteristics of EDPSCs,generation principles and interactions among the interharmonics in the PVGS are presented by the sequence components,and its correctness is verified by simulation and experiment.The presented model can be used to accurately calculate the interharmonics generated in the PVGS both at the AC and DC sides. Because of the decoupling among the EDPSCs, the set of state space equations can effectively describe the principle. | Qing Zhong Yangxin Qiu Yuming Zhao Haifeng Li Gang Wang Fushuan Wen | 2021 | Journal of Modern Power Systems and Clean Energy2021，9，6： | 0 |
| 15 | One-Pot Synthesis of Axially and Centrally Chiral A-type Nanogrids显示文摘A novel type of A-type nanogrids(AGs)with axial and central chirality was synthesized via Friedel-Crafts gridization of thiophenes and difluorenyl biaromatic derivatives,yielding 9%-30%.Additionally,the effect of stereoisomers of 1,1'-binaphthyl difluorenols(BINDFOH)was investigated to demonstrate that R/S-BINDFOH is more advantageous for the synthesis of AGs than Mix-BINDFOH.Furthermore,tests on OFET memory devices showed that AGs have a larger storage window,indicating potential for data storage applications. | Ying Wei Xue Du Wan-Xin Huang Ming-Yang Fu Zheng Zhang Chun-Xiao Zhong Yi-Ru Wang HaiFeng Ling Ling-Hai Xie Wei Huang | 2023 | Chinese Journal of Chemistry2023，41，22： | 0 |
| 16 | Increased maternal consumption of methionine as its hydroxyl analog promoted neonatal intestinal growth without compromising maternal energy homeostasis显示文摘Background: To determine responses of neonatal intestine to maternal increased consumption of DL-methionine(DLM) or DL-2-hydroxy-4-methylthiobutanoic acid(HMTBA), eighteen primiparous sows(Landrace × Yorkshire) were allocated based on body weight and backfat thickness to the control, DLM and HMTBA groups(n = 6), with the nutritional treatments introduced from postpartum d0 to d14.Results: The DLM-fed sows showed negative energy balance manifested by lost bodyweight, lower plasma glucose, subdued tricarboxylic acid cycle, and increased plasma lipid metabolites levels. Both villus height and ratio of villus height to crypt depth averaged across the small intestine of piglets were higher in the DLM and HMTBA groups than in the control group. Piglet jejunal oxidized glutathione concentration and ratio of oxidized to reduced glutathione were lower in the HMTBA group than in the DLM and control groups. However, piglet jejunal aminopeptidase A, carnitine transporter 2 and IGF-II precursor m RNA abundances were higher in the DLM group than in the HMTBA and control groups.Conclusion: Increasing maternal consumption of methionine as DLM and HMTBA promoted neonatal intestinal growth by increasing morphological development or up-regulating expression of genes responsible for nutrient metabolism. And increasing maternal consumption of HMTBA promoted neonatal intestinal antioxidant capacity without compromising maternal energy homeostasis during early lactation. | Heju Zhong Hao Li Guangmang Liu Haifeng Wan Yves Mercier Xiaoling Zhang Yan Lin Lianqiang Che Shengyu Xu Li Tang Gang Tian Daiwen Chen De Wu Zhengfeng Fang | 2017 | Journal of Animal Science and Biotechnology2017，8，1： | 0 |
| 17 | Detect and attribute the extreme maize yield losses based on spatio-temporal deep learning显示文摘Providing accurate crop yield estimations at large spatial scales and understanding yield losses under extreme climate stress is an urgent challenge for sustaining global food security.While the data-driven deep learning approach has shown great capacity in predicting yield patterns,its capacity to detect and attribute the impacts of climatic extremes on yields remains unknown.In this study,we developed a deep neural network based multi-task learning framework to estimate variations of maize yield at the county level over the US Corn Belt from 2006 to 2018,with a special focus on the extreme yield loss in 2012.We found that our deep learning model hindcasted the yield variations with good accuracy for 2006-2018(R^(2)=0.81)and well reproduced the extreme yield anomalies in 2012(R^(2)=0.79).Further attribution analysis indicated that extreme heat stress was the major cause for yield loss,contributing to 72.5%of the yield loss,followed by anomalies of vapor pressure deficit(17.6%)and precipitation(10.8%).Our deep learning model was also able to estimate the accumulated impact of climatic factors on maize yield and identify that the silking phase was the most critical stage shaping the yield response to extreme climate stress in 2012.Our results provide a new framework of spatio-temporal deep learning to assess and attribute the crop yield response to climate variations in the data rich era. | Renhai Zhong Yue Zhu Xuhui Wang Haifeng Li Bin Wang Fengqi You Luis F.Rodríguez Jingfeng Huang K.C.Ting Yibin Ying Tao Lin | 2023 | Fundamental Research2023，3，6： | 0 |
| 18 | Advances in the construction of in vitro liver tissue models using 3D bioprinting technology显示文摘The liver,being the largest solid organ in the human body,performs a multitude of essential physiological functions,including digestion,metabolism,detoxification,and protein synthesis(1).Impairment of liver function due to disease or surgical intervention can result in a reduction of functional liver volume,with potentially severe or even life-threatening consequences(2). | Chengyi Zhong Haifeng Xu | 2023 | Hepatobiliary Surgery and Nutrition2023，12，5： | 0 |
| 19 | Cooperative control of perpendicular magnetic anisotropy via crystal structure and orientation in freestanding SrRuO_(3)membranes显示文摘Flexible magnetic materials with robust and controllable perpendicular magnetic anisotropy(PMA)are highly desirable for developing flexible high-performance spintronic devices.However,it is still challenge to fabricate PMA films on polymers directly.Here,we report a facile method for synthesizing single-crystal freestanding SrRuO_(3) membranes with controlled crystal structure and orientation using water-soluble Ca_(3-x)Sr_(x)Al_(2)O_(3)6 sacrificial layers.Through cooperative effect of crystal structure and orientation,flexible membranes reveal highly tunable magnetic anisotropy from in-plane to out-of-plane with a remarkable PMA energy of 7×10^(6) erg·cm^(−3).First-principle calculations reveal that the underlying mechanism of PMA modulation is intimately correlated with structure-controlled Ru 4d-orbital occupation,as well as spin-orbital matrix element differences,dependent on the crystal orientation.In addition,even after 10,000 bending cycles,the PMA keeps stable,indicating a robust magnetism reliability in the prepared films.This work provides a feasible approach to prepare the flexible oxide films with strong and controllable PMA. | Zengxing Lu Yongjie Yang Lijie Wen Jiatai Feng Bin Lao Xuan Zheng Sheng Li Kenan Zhao Bingshan Cao Zeliang Ren Dongsheng Song Haifeng Du Yuanyuan Guo Zhicheng Zhong Xianfeng Hao Zhiming Wang Run-Wei Li | 2022 | npj Flexible Electronics2022，6，1： | 0 |
| 20 | Clinical characteristics of hospitalised patients with schizophrenia who were suspected to have coronavirus disease(COVID-19)in Hubei Province,China显示文摘Background Since the outbreak of C0VID-19,no data have been available for hospitalised psychiatric patients who are suspected to have COVID-19.We performed a comprehensive investigation of the clinical features of hospitalised patients with schizophrenia with or without suspected COVID-19 in Hubei Province,China.Aim To explore the clinical characteristics of hospitalised patients with schizophrenia with suspected COVID-19 in Hubei Province,China.M ethods 21 hospitalised patients with schizophrenia with suspected COVID-19(COVID-19 suspected group)in the isolation ward of a mental health hospital in Wuhan and 30 hospitalised patients with schizophrenia(clean group)in the general ward of another mental health hospital in Yichang were recruited.We retrospectively reviewed their clinical characteristics,laboratory findings and chest CT results before 21 February 2020.We also compared the emotional and mental symptoms between the two groups.Results Medical records revealed that 21 COVID-19 suspected patients were transferred to the isolation ward between 30 January 2020 and 15 February 2020.The mean age(SD)of COVID-19 suspected patients was 43.1(2.6).12(57.1%)patients showed abnormalities on chest CT before onset of respiratory symptoms.14(66.7%)patients had psychiatric medications adjustment after detection of abnormal chest CT findings.By 21 February,one patient was confirmed to have COVID-19.Even though the remaining 20(95.2%)were negative for at least two reverse transcription PCR tests,11(52.4%)patients met the diagnostic criteria for clinically confirmed cases.Compared with patients in the clean group,patients in the suspected COVID-19 group showed significantly higher stress,depression and anxiety levels and poorer sleep quality.Conclusion Setting up an independent isolation ward for hospitalised psychiatric patients who are suspected to have symptoms of COVID-19 helped control the spread of the epidemic.Patients with schizophrenia suspected to have COVID-19 showed increased stress and mood and sleep disturbances,which should be appropriately managed. | Xuebing Liu Hong Lin Haifeng Jiang Ruihua Li Na Zhong Hang Su Yi Li Min Zhao | 2020 | General Psychiatry2020，33，2： | 0 |
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