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| 1 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019，16，1： | 14 |
| 2 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 3 | Bevacizumab biosimilar LY01008 compared with bevacizumab(Avastin)as first-line treatment for Chinese patients with unresectable,metastatic,or recurrent non-squamous non-small-cell lung cancer:A multicenter,randomized,double-blinded,phase Ⅲ trial显示文摘Background:Previous studies have demonstrated the preclinical pharmacological and toxicological consistency,and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab(Avastin).This randomized controlled trial aimed to compare the efficacy and safety of LY01008 with Avastin in first-line treatment of Chinese patients with advanced or recurrent non-squamous non-small cell lung cancer(NSCLC).Methods:StageⅢB-ⅣNSCLC patients with evaluable lesions,good physical status,and adequate organ functions from 67 centers across China were randomized in a ratio of 1:1 to receive LY01008 or Avastin 15 mg/kg intravenously in combination with paclitaxel/carboplatin(combined treatment)for 4-6 cycles,followed by maintenance monotherapy with LY01008 until disease progression,intolerable toxicity,or death.The primary endpoint was objective response rate(ORR)in accordance with Response Evaluation Criteria in Solid Tumors(RECIST)version 1.1 confirmed by independent radiological review committees(IRRC).Secondary endpoints included disease control rate(DCR),duration of response(DoR),progression-free survival(PFS),overall survival(OS),and safety.This study was registered in Clinical Trials.gov(NCT03533127).Results:Between December 15^(th),2017,and May 15^(th),2019,a total of 649 patients were randomized to the LY01008(n=324)or Avastin(n=325)group.As of September 25th,2019 for primary endpoint analysis,589 patients received ORR evaluation,with a median number of combined treatment cycles of 5(range 1-6)andmedian duration of treatment of 3.0(range 0.0-5.1)months.ORRof responseevaluable patients in the LY01008 and Avastin groups were 48.5% and 53.0%,respectively.The stratified ORR ratio was 0.91(90%CI 0.80-1.04,within the prespecified equivalence margin of 0.75-1.33).Up to May 15^(th),2020,with a median follow-up of 13.6(range 0.8-28.4)months,no notable differences in DCR,median DoR,median PFS,median OS,and 1-year OS rate were observed between the LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,LY01008 and Avastin groups.There were no clinically meaningful differences in safety and immunogenicity across treatment groups.Conclusions:LY01008 demonstrated similarity to Avastin in terms of efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC.LY01008 combined with paclitaxel/carboplatin is expected to become a new treatment option for unresectable,metastatic,or recurrent non-squamous NSCLC patients in the first-line setting. | Yuankai Shi Kaijian Lei Yuming Jia Bingqiang Ni Zhiyong He Minghong Bi Xicheng Wang Jianhua Shi Ming Zhou Qian Sun Guolei Wang Dongji Chen Yongqian Shu Lianke Liu Zhongliang Guo Yong Liu Junquan Yang Ke Wang Ke Xiao LinWu Tienan Yi Debin Sun Mafei Kang Tianjiang Ma Yimin Mao Jinsheng Shi Tiegang Tang Yan Wang Puyuan Xing Dongqing Lv Wangjun Liao Zhiguo Luo Bin Wang Xiaohong Wu Xiaoli Zhu Shuhua Han Qisen Guo Rongyu Liu Zhiwei Lu Jianyong Zhang Jian Fang Changlu Hu Yinghua Ji Guolong Liu Hong Lu Dedong Wu Junhong Zhang Shuyang Zhu Zheng Liu Wensheng Qiu Feng Ye Yan Yu Yanqiu Zhao Qinhong Zheng Jun Chen Zhanyu Pan Yiping Zhang Wenjuan Lian Bo Jiang Bo Qiu Guojun Zhang Hua Zhang Yanju Chen Yuan Chen Hongbing Duan Manxiang Li Shengming Liu Lijun Ma Hongming Pan Xia Yuan Xueli Yuan Yulong Zheng Emei Gao Li Zhao Shumin Wang Can Wu | 2021 | Cancer Communications2021，41，9： | 5 |
| 4 | Selective depression action of taurine in flotation separation of specularite and chlorite显示文摘Chlorite,as the most representative gangue mineral associated with specularite,of which the separation of these two minerals is difficult.This paper investigated the depression effect of taurine on specularite/chlorite separation via flotation experiments,adsorption tests,contact angle measurements,Zeta potential detection,FT-IR measurements,and XPS analyses.The results of single mineral flotation indicated that chlorite could be depressed selectively by taurine with the recovery of less than 30%,but the floatability of specularite remains high with recovery rate of 81.77%at pH 10.The artificial mixed mineral flotation results confirmed the effectiveness of taurine as a depressant.Surface adsorption,contact angle,and Zeta potential detection revealed taurine primarily adsorbs on the chlorite surface,which hampered the DDA’s subsequent adsorption and results in the chlorite’s poor floatability.The FT-IR spectra and XPS analyses provided further proof that taurine adsorbed on chlorite surface as an electron donor,and part of the electrons transferred from the sulfonic acid group of taurine to metal ions during the adsorption process.In addition,the hydrogen bond between amino-group of taurine and O ions in chlorite surface was also formed in the adsorption process.Finally,optimized adsorption configurations of taurine on chlorite surfaces were proposed. | Mingyang Li Cheng Yang Zhaoyang Wu Xiangpeng Gao Xiong Tong Xiankun Yu Hongming Long | 2022 | International Journal of Mining Science and Technology2022，32，3： | 4 |
| 5 | Analysis of Gas-Solid Flow Characteristics in a Spouted Fluidized Bed Dryer by Means of Computational Particle Fluid Dynamics显示文摘In order to grasp the particle flow characteristics and energy consumption of industrial fluidized spouted beds,we conduct numerical simulations on the basis of a Computational Particle Fluid Dynamics(CPFD)approach.In particular,the traction model of Wen-Yu-Ergun is used and different inlet conditions are considered.Using a low-speed fluidizing gas,the flow state of the particles is better and the amount of particles accumulated at the bottom of the bed wall becomes smaller.For the same air intake,the energy loss of a circular nozzle is larger than that of a square nozzle. | Hongming Zhou Haozheng Gao Zheng Fang Jiangxin Yang Mingge Wu | 2020 | Fluid Dynamics & Materials Processing2020，16，4： | 3 |
| 6 | Current Density Distribution in Double-Sided GTAW Process显示文摘A three dimensional current density distribution in double-sided gas tungsten arc welding (GTAW) proces is performed. The current density distribution field is evaluated by numerically solving Maxwell equations in the domain of the workpiece. In the boundary condition, the current density on. the workpiece surface is assumed as Gaussian distribution. Results show that the current distribution in DSAW is different from single side arc welding, it is more concentrated and the relative location of the two torches influence the current distribution greatly. | Hongming GAO Lin WU and Honggang DONG National Key Laboratory of Advanced Welding Production Technology, Harbin institute of Technology, Harbin 150001, China | 2001 | Journal of Materials Science & Technology2001，17，1： | 2 |
| 7 | Interface Behavior of Copper and Steel by Plasma-MIG Hybrid Arc Welding显示文摘Plasma-MIG hybrid arc welding is a hybrid heating source welding method which is composed of plasma arc and MIG arc. During Plasma-MIG hybrid arc welding process, the interface behavior of copper and steel dissimilar alloy is investigated. The results show that electromagnetic stirring effect decreases and the heat input increases with the increase of outer plasma current in the hybrid arc welding process. The interface diffusion and interface thickness is controlled by the tradeoff of electromagnetic stirring effect degradation and heat input increase. The interface diffusion and interface thickness are controlled by decreasing the electromagnetic stirring force and increasing the heat input with the increase of plasma current in Cu/Fe plasma-MIG hybrid arc welding process. | Tao YANG Hongming GAO Shenghu ZHANG Lin WU | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，3： | 2 |
| 8 | Tuning the properties of Ni-based catalyst via La incorporation for efficient hydrogenation of petroleum resin显示文摘The hydrogenation of petroleum resin(PR)is an effective process to prepare high value-added hydrogenated PR(HPR).However,the preparation of non-noble metal-based catalysts with high catalytic activity for PR hydrogenation still remains a challenge.Herein,a La promoted Ni-based catalyst is reported through the thermal reduction of quaternary Ni La Mg Al-layered double hydroxides(Ni La Mg Al-LDHs).The incorporation of La is beneficial to the reduction and stability of Ni particles with reduced particle size,and the increased alkalinity effectively mitigates the breakage of molecular chains of PR.As a result,the La promoted Ni-based catalyst exhibits high catalytic activity and excellent stability for PR hydrogenation.A hydrogenation degree of 95.4%and 96.1%can be achieved for HC_(5)PR and HC_(9) PR with less reduced softening point,respectively.Notably,the hydrogenation degree still maintains at 92.7%even after 100 hours’reaction,much better than that without La incorporation or prepared using conventional impregnation method. | Qunhong Liu Jiangtao Yang Hongwei Zhang Hongming Sun Shuzheng Wu Bingqing Ge Rong Wang Pei Yuan | 2022 | Chinese Journal of Chemical Engineering2022，35，5： | 2 |
| 9 | Rice FLOURY ENDOSPERM 18 encodes a pentatricopeptide repeat protein required for 5′ processing of mitochondrial nad5 messenger RNA and endosperm development显示文摘Pentatricopeptide repeat(PPR) proteins, composing one of the largest protein families in plants,are involved in RNA binding and regulation of organelle RNA metabolism at the posttranscriptional level. Although several PPR proteins have been implicated in endosperm development in rice(Oryza sativa), the molecular functions of many PPRs remain obscure. Here, we identified a rice endosperm mutant named floury endosperm 18(flo18) with pleiotropic defects in both reproductive and vegetative development.Map-based cloning and complementation tests showed that FLO18 encodes a mitochondriontargeted P-type PPR protein with 15 PPR motifs.Mitochondrial function was disrupted in the flo18 mutant, as evidenced by decreased assembly of Complex I in the mitochondrial electron transport chain and altered mitochondrial morphology. Loss of FLO18 function resulted in defective 5′-end processing of mitochondrial nad5 transcripts encoding subunit 5 of nicotinamide adenine dinucleotide hydrogenase. These results suggested that FLO18 is involved in 5′-end processing of nad5 messenger RNA and plays an important role in mitochondrial function and endosperm development. | Mingzhou Yu Mingming Wu Yulong Ren Yihua Wang Jingfang Li Cailin Lei Yinglun Sun Xiuhao Bao Hongming Wu Hang Yang Tian Pan Yongfei Wang Ruonan Jing Mengyuan Yan Houda Zhang Lei Zhao Zhichao Zhao Xin Zhang Xiuping Guo Zhijun Cheng Bing Yang Ling Jiang Jianmin Wan | 2021 | Journal of Integrative Plant Biology2021，63，5： | 2 |
| 10 | Nutritional evaluation of whole soybean curd made from different soybean materials based on amino acid profiles显示文摘Objectives:Amino acid profiles of whole soybean curds(WSCs)and conventional soybean curds(CSCs)were comparatively studied to 1.,evaluate their nutritional value and 2.,study the suitable soybean material to fabricate WSCs.Materials and Methods:Nine types of soybean materials were selected to make WSCs and CSCs.Protein digestibility-corrected amino acid score(PDCAAS)and principal component analysis were selected to perform the comparative analysis of amino acid profiles of the products.Results:Total contents of amino acids in WSCs and CSCs were 41.24-54.87 mg/g and 27.77-36.82 mg/g.Content ranges of essential amino acids were 13.59-19.38 mg/g and 8.46-11.76 mg/g for WSCs and CSCs.The essential amino acid pattern of WSCs was basically close to amino acid pattern spectrum requirements except valine and sulfur amino acids.As a limiting amino acid,methionine represented less than 0.4 for PDCAAS in all soybean curds except WSCs made from relay-cropping Nandou12 and Nandou25.Conclusions:The overall quality of amino acids in WSCs was higher than that in CSCs,indicating that WSCs indeed exhibited higher nutritional value than CSCs from the viewpoint of amino acid profile.WSCs with the high nutritional value could be made using Nandou25 and relay-cropping Nandou12 as materials. | Meili Li Hongming Dong Dingtao Wu Hong Chen Wen Qin Weiguo Liu Wenyu Yang Qing Zhang | 2020 | Food Quality and Safety2020，4，1： | 2 |
| 11 | Degradation of 2,4-DCP by the Immobilized Laccase on the Carrier of Fe304@SiO2-NH2显示文摘在这份报纸,在 Fe3O4@SiO2-NH2 nanoparticles 上使不能调动的 laccase 被 glutaraldehyde cross-linking 方法成功地准备。laccase 催化并且使 laccase 不能调动的 2,4-dichlorophenol (2,4-DCP ) 的降级被执行。关于降级效率的最佳的条件也被讨论,它包括反应时间, pH 价值,温度, 2,4-DCP 和 laccase 的集中。当 laccase 被 crosslinking 与 glutaraldehyde 在 Fe3O4@SiO2-NH2 搬运人上使不能调动时,稳定性和重复显著地被改进。由使不能调动的 laccase 的 2,4-DCP 的移动效率在操作的六个周期以后仍然是超过 59% 。 2,4-DCP 的降级是一阶的反应, laccase 催化并且使 laccase 不能调动的 2,4-DCP 的激活精力是 51.93 kJ 敶?湡?硥楨楢整?楨桧猠汥'虡N楶祴愠摮猠湥楳楴楶祴映牯???潩獮?獁愠???浡汰晩敩?汦潵敲'諟?牰扯??獴映畬牯獥散据?灳'虪箾溪e潨敷???潦摬攠桮湡散敭瑮椠?桴?湩整獮瑩?景琠敨猠杩慮?瑡??渠?湯戠湩楤杮眠瑩?桴?牃??慂敳?湯琠敨映畬牯獥散据?楴牴瑡潩?灳'虪?湡?潊??汰瑯愠慮祬楳?戠湩楤杮洠摯?景丠児?眠瑩?牃?眠獡瀠潲潰敳??畬牯獥散据?湩整獮瑩?慷?楬敮牡眠瑩?潣据湥牴瑡潩?景???慣楴湯椠?? | Huan Weiwei Yang Yuxiang Wu Bin Yuan Hongming Zhang Yani Liu Xiangnong | 2012 | Chinese Journal of Chemistry2012，30，12： | 2 |
| 12 | Current Density Distribution in Gas Tungsten Arc Welding Process显示文摘Heat transfer and fluid flow in a weld pool had been simulated for several decades, which underwent from theoretically analysis to numerical solutions. Because of the complexity of the welding process, many ideal assumptions were made to simplify the question. This makes the solution somewhat not complied with the practical conditions. In previous papers, the current distribution in the weld pool is assumed as axi-symmetrical, and so does the electromagnetic forces, which plays an important role in determining the fluid flow field. Actually the current distribution is different from the assumption. In this paper; a three dimensional current distribution in Gas Tungsten Arc Welding (GTAW) process is performed. The current density distribution field is evaluated by numerically solving Maxwell’s equations in the domain of the workpiece. In the boundary condition, the current density on the top surface is assumed as Gaussian distribution. Results show that the current distribution in GTAW is not axi-symmetrical, and the relative location of the torch and the earth clamp influence the current distribution greatly. | Hongming GAO Lin WU Honggang DONG National Key Laboratory of Advanced Welding Production Technology, Harbin Institute of Technology, Harbin, 150001, China | 2000 | Journal of Shanghai Jiaotong university(Science)2000，5，1： | 2 |
| 13 | Experimental study on enhancement of the metastatic potential of portal vein tumor thrombus-originated hepatocellular carcinoma cells using portal vein serum显示文摘Objective: Portal vein metastasis of hepatocellular carcinoma(HCC) results in a poor prognosis and seriously affects the survival rate of patients. The mechanism underlying the formation of portal vein tumor thrombus(PVTT) is complex and is not yet fully understood. This study was conducted to investigate the impact of portal vein blood on the proliferation, metastasis, invasion and apoptosis of PVTT cells and to explore its possible mechanisms, which was expected to lay a foundation for ascertaining the mechanism underlying the portal vein metastasis of HCC.Methods: Peripheral blood and portal vein blood were collected from patients with HCC, and the sera from these two sources were used to culture the PVTT-originated HCC cell line CSQT-2. The cells were collected after 24 h, and flow cytometry was performed to detect cell proliferation, cell cycle stages and apoptosis. Transwell migration and invasion assays were applied to detect the metastasis and invasion of the cells in each group. The changes in the expression of MMP-2 and MMP-9 in cells were detected via Western blotting. The contents of IL-12, IFN-γ, IL-1β, IL-2 and TNF-α in the two groups of sera were quantified using corresponding kits. Results: Compared with the group of cells cultured with peripheral serum, the cells cultured with portal vein serum showed significantly lower apoptosis(P<0.01), significantly enhanced cell metastasis and invasion(P<0.01), whereas cell proliferation and the stages of the cell cycle did not differ significantly(P>0.05). A significantly increased expression level of MMP-2 has been observed in tumor cells treated portal vein serum. In addition, compared with peripheral serum, the content of IL-12 was significantly decreased in portal vein serum(P<0.05), while the contents of IFN-γ, IL-1β, IL-2, and TNF-α did not differ significantly(P>0.05). Conclusions: Portal vein serum from HCC patients could inhibit the apoptosis of PVTT-originated HCC cells and promote cell metastasis and invasion. This effect may be related to the lower level of IL-12 in portal vein serum. | Yufu Tang Hongming Yu Long Zhang Kang Wang Weixing Guo Jie Shi Shupeng Liu Mengchao Wu Hongyang Wang Shuqun Cheng | 2014 | Chinese Journal of Cancer Research2014，26，5： | 2 |
| 14 | Preparation of Nano-structured LiFe_xMn_(1-x)PO_4(x=0,0.2,0.4) by Reflux Method and Research on the Influences of Fe(Ⅱ) Substitution显示文摘Nano structured LiFexMn1-xPO4(x=0,0.2,0.4) materials were successfully prepared by one-step reflux method in a water/PEG400 mixed solvent, and were coated by carbon using glucose as the precursor. The materials were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The electrochemical properties of the materials were investigated by galvanostatic cycling, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). It was found that the materials consisted of nanorods with a diameter of 50 nm and a length of 500 nm. Galvanostatic cycling showed that the capacity of LiMnPO 4 could be largely increased by Fe2+ substitution. At a current rate of C/20, the capacity of the three samples (x=0,0.2,0.4) were 47, 107 and 150 mA·h·g-1 , respectively. CV result showed that the Fe2+ substitution could decrease the polarization during charging/discharging, accelerating the electrochemical process. EIS result showed that the Fe2+ substitution could decrease the charge transfer resistance between the electrode and electrolyte, | Zhao Yang Hongming Yu Chunyang Wu Gaoshao Cao Jian Xie Xinbing Zhao | 2012 | Journal of Materials Science & Technology2012，28，9： | 2 |
| 15 | Effect of spark timing and load on a DISI engine fuelled with 2,5-dimethylfuran显示文摘 | Ritchie Daniel Guohong Tian Hongming Xu Miroslaw L. Wyszynski Xuesong Wu Zuohua Huang | 2010 | Fuel2010，，2： | 1 |
| 16 | Modelling the response of surface water quality to the urbanization in Xi'an, China 显示文摘 | HE Hongming ZHOU Jie WU Yong jao | 2008 | Journal of Environmental Management2008，86，4： | 1 |
| 17 | Behavior of Corrosion-Repaired Concrete Beams Reinforced by Epoxy Mortar显示文摘The performance of concrete beams repaired with epoxy mortar was investigated by constructing twelve beam specimens.All the beam specimens were subjected to a constant current for accelerated corrosion.Six specimens were corroded without subsequent reparation as a control group,and the other six beam specimens were corroded and repaired utilizing epoxy mortar.All specimens were tested to failure.During test process,we focused on the failure pattern of beam specimens,structural cracks,mid-deflections,bearing capacity,and probed into the influence of corrosion degree and repair of epoxy mortar on the performance of beam specimens.It was observed that corrosion-repaired beams in the loading test were in a bending failure pattern.It is obvious that cracking loads and bending stiffness of repaired beams and corrosion-repaired beams were larger than those of unrepaired beams and secondly-corroded beams.When the mass loss of main steel bars was smaller than 10%,the bearing capacity of the repaired beams was similar to that of the unrepaired beams.When the mass loss of main steel bars was larger than 10%,the bearing capacity of the repaired beams increased significantly compared with that of the unrepaired beams. | Wu Jin Tang Jinzhi Li Hongming Shang Baokang Wang Zhe | 2016 | Transactions of Nanjing University of Aeronautics and Astronautics2016，33，3： | 1 |
| 18 | Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial显示文摘 | Yi-Long Wu Jin Soo Lee Sumitra Thongprasert Chong-Jen Yu Li Zhang Guia Ladrera Vichien Srimuninnimit Virote Sriuranpong Jennifer Sandoval-Tan Yunzhong Zhu Meilin Liao Caicun Zhou Hongming Pan Victor Lee Yuh-Min Chen Yan Sun Benjamin Margono Fatima Fuerte | 2013 | Lancet Oncology2013，，8： | 1 |
| 19 | Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial显示文摘 | Yi-Long Wu Jin Soo Lee Sumitra Thongprasert Chong-Jen Yu Li Zhang Guia Ladrera Vichien Srimuninnimit Virote Sriuranpong Jennifer Sandoval-Tan Yunzhong Zhu Meilin Liao Caicun Zhou Hongming Pan Victor Lee Yuh-Min Chen Yan Sun Benjamin Margono Fatima Fuerte | 2013 | Lancet Oncology2013，，8： | 1 |
| 20 | 显示文摘 | Huang Shuchun Chen Hongming Wu Shichuan | 1998 | J Appl Phys1998，84，9： | 1 |
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