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| 1 | Monolithic integration of MoS2-based visible detectors and GaN-based UV detectors显示文摘With the increasing demand for high integration and multi-color photodetection for both military and civilian applications, the research of multi-wavelength detectors has become a new research hotspot. However, current research has been mainly in visible dual-or multi-wavelength detectors, while integration of both visible light and ultraviolet(UV) dual-wavelength detectors has rarely been studied. In this work, large-scale and high-quality monolayer MoS2 was grown by the chemical vapor deposition method on transparent free-standing GaN substrate. Monolithic integration of MoS2-based visible detectors and GaN-based UV detectors was demonstrated using common semiconductor fabrication technologies such as photolithography, argon plasma etching, and metal deposition. High performance of a 280 nm and 405 nm dual-wavelength photodetector was realized.The responsivity of the UV detector reached 172.12 A/W, while that of the visible detector reached 17.5 A/W.Meanwhile, both photodetectors achieved high photocurrent gain, high external quantum efficiency, high normalized detection rate, and low noise equivalent power. Our study extends the future application of dual-wavelength detectors for image sensing and optical communication. | YOU WU ZHIWEN LI KAH-WEE ANG YUPING JIA ZHIMING SHI ZHI HUANG WENJIE YU XIAOJUAN SUN XINKE LIU DABING LI | 2019 | Photonics Research2019，7，10： | 4 |
| 2 | Experimental Wave Power Plant at the Pearl River Estuary显示文摘The first Chinese experimental wave power plant, i. e., the shoremountcd experimental wave power plant at the Pearl River Estuary was successful in trial power generation on February 15, 1990. The plant is on the south shore of the Dawanshan Island in the Pearl River Estuary, facing the vast waving South China Sea. With a designed wave condition of H1/10= 1.5 m and T= 6.5 s, the planned installed capacity is 8 kW comprising the first unit of 3 kW brushless clawpole generator which delivers 110 V DC current and the second unit of 5 kW brushless single phase synchro AC generator which delivers 220 V AC current. At present, the first unit has been put into trial operation. | Liang Xianguang, Gao Xiangfan, Zheng Wenjie Yu Zhi, Jiang Niandong, Hou Xiangqin and You Yage 1. Associate Professor, Guangzhou Institute of Energy Conversion, the Chinese Academy of Sciences, Guangzhou2. Senior Engineer, Guangzhou Institute of Energy Conversion, the Chinese Academy of Sciences, Guangzhou3. Assistant Researcher, Guangzhou Institute of Energy Conversion, the Chinese Academy of Sciences, Guangzhou4. Engineer, Guangzhou Institute of Energy Conversion, the Chinese Academy of Sciences, Guangzhou | 1991 | China Ocean Engineering1991，6，4： | 1 |
| 3 | Overexpression of Bmi-1 contributes to the invasion and metastasis ofhepatocellular carcinoma by increasing the expression of matrix metalloproteinase(MMP)?2, MMP-9 and vascular endothelial growth factor via the PTEN/PI3K/Akt pathway显示文摘 | Xiaolei Li Zhaoxu Yang Wenjie Song Liang Zhou Qingjun Li Kaishan Tao Jingshi Zhou Xing Wang Zhigang Zheng Nan You Kefeng Dou Haimin Li | 2013 | International Journal of Oncology2013，，3： | 1 |
| 4 | Using partialleast squares and support vector machines forbankruptcy prediction 显示文摘 | Yang Zijiang You Wenjie Ji Guoli | 2011 | Expert Systems withApplications2011，38，7： | 1 |
| 5 | Operando reconstruction towards stable CuI nanodots with favorable facets for selective CO_(2) electroreduction to C2H4显示文摘Cu-based electrocatalysts with favorable facets and Cu^(+)can boost CO_(2) reduction to valuable multicarbon products.However,the inevitable Cu^(+)reduction and the phase evolution usually result in poor performance.Herein,we fabricate CuI nanodots with favorable(220)facets and a stable Cu^(+)state,accomplished by operando reconstruction of Cu(OH)_(2) under CO_(2)-and I--containing electrolytes for enhanced CO_(2)-to-C_(2)H_(4) conversion.Synchrotron X-ray absorption spectroscopy(XAS),in-situ Raman spectroscopy and thermodynamic potential analysis reveal the preferred formation of CuI.Vacuum gas electroresponse and density functional theory(DFT)calculations reveal that CO_(2)-related species induce the exposure of the(220)plane of Cu I.Moreover,the small size of nanodots enables the adequate contact with I^(-),which guarantees the rapid formation of Cu I instead of the electroreduction to Cu^(0).As a result,the resulting catalysts exhibit a high C2H4 Faradaic efficiency of 72.4%at a large current density of 800 m A cm^(-2) and robust stability for 12 h in a flow cell.Combined in-situ ATR-SEIRS spectroscopic characterizations and DFT calculations indicate that the(220)facets and stable Cu^(+) in CuI nanodots synergistically facilitate CO_(2)/*CO adsorption and*CO dimerization. | Wenjie Xue Hongxia Liu Xinqing Chen Xiaoju Yang Ruoou Yang Youwen Liu Minghao Li Xuan Yang Bao Yu Xia Bo You | 2023 | Science China Chemistry2023，66，6： | 1 |
| 6 | Carrier mobility tuning of MoS_(2) by strain engineering in CVD growth process显示文摘Strain engineering is proposed to be an effective technology to tune the properties of two-dimensional(2D)transition metal dichalcogenides(TMDCs).Conventional strain engineering techniques(e.g.,mechanical bending,heating)cannot conserve strain due to their dependence on external action,which thereby limits the application in electronics.In addition,the theoretically predicted strain-induced tuning of electrical performance of TMDCs has not been experimentally proved yet.Here,a facile but effective approach is proposed to retain and tune the biaxial tensile strain in monolayer MoS_(2) by adjusting the process of the chemical vapor deposition(CVD).To prove the feasibility of this method,the strain formation model of CVD grown MoS_(2) is proposed which is supported by the calculated strain dependence of band gap via the density functional theory(DFT).Next,the electrical properties tuning of strained monolayer MoS_(2) is demonstrated in experiment,where the carrier mobility of MoS_(2) was increased by two orders(~0.15 to~23 cm^(2)·V^(−1)·s^(−1)).The proposed pathway of strain preservation and regulation will open up the optics application of strain engineering and the fabrication of high performance electronic devices in 2D materials. | Yongfeng Chen Wenjie Deng Xiaoqing Chen Yi Wu Jianwei Shi Jingying Zheng Feihong Chu Beiyun Liu Boxing An Congya You Liying Jiao Xinfeng Liu Yongzhe Zhang | 2021 | Nano Research2021，14，7： | 0 |
| 7 | p-/n-Type modulation of 2D transition metal dichalcogenides for electronic and optoelectronic devices显示文摘Two-dimensional layered transition metal dichalcogenides(TMDCs)have demonstrated a huge potential in the broad fields of optoelectronic devices,logic electronics,electronic integration,as well as neural networks.To take full advantage of TMDC characteristics and efficiently design the device structures,one of the most key processes is to control their p-/n-type modulation.In this review,we summarize the p-/n-type modulation of TMDCs based on diverse strategies consisting of intrinsic defect tailoring,substitutional doping,surface charge transfer,chemical intercalation,electrostatic modulation,and dielectric interface engineering.The modulation mechanisms and comparisons of these strategies are analyzed together with a discussion of their corresponding device applications in electronics and optoelectronics.Finally,challenges and outlooks for p-/n-type modulation of TMDCs are presented to provide references for future studies. | Songyu Li Yang Ma Nabonswende Aida Nadege Ouedraogo Famin Liu Congya You Wenjie Deng Yongzhe Zhang | 2022 | Nano Research2022，15，1： | 0 |
| 8 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 9 | Growth of centimeter scale Nb_(1−x)W_(x)Se_(2) monolayer film by promoter assisted liquid phase chemical vapor deposition显示文摘Two-dimensional(2D)transition-metal dichalcogenide materials(TMDs)alloys have a wide range of applications in the field of optoelectronics due to their capacity to achieve wide modulation of the band gap with fully tunable compositions.However,it is still a challenge for growing alloys with uniform components and large lateral size due to the random distribution of the crystal nucleus locations.Here,we applied a simple but effective promoter assisted liquid phase chemical vapor deposition(CVD)method,in which the quantity ratio of promoter to metal precursor can be controlled precisely,leading to tiny amounts of transition metal oxide precursors deposition onto the substrates in a highly uniform and reproducible manner,which can effectively control the uniform distribution of element components and nucleation sites.By this method,a series of monolayer Nb_(1−x)W_(x)Se_(2)alloy films with fully tunable compositions and centimeter scale have been successfully synthesized on sapphire substrates.This controllable approach opens a new way to produce large area and uniform 2D alloy film,which has the potential for the construction of optoelectronic devices with tailored spectral responses. | Boxing An Yang Ma Feihong Chu Xuhong Li Yi Wu Congya You Wenjie Deng Songyu Li Yongzhe Zhang | 2022 | Nano Research2022，15，3： | 0 |
| 10 | Ultra-dense planar metallic nanowire arrays with extremely large anisotropic optical and magnetic properties显示文摘为对晶片尺寸可伸缩的极端稠密的平面金属性的 nanowire 数组的生产的一个 nanofabrication 方法被介绍。方法基于一个有效模板免职过程在仅仅二步与极端整齐种多样的金属性的 nanowire 数组。首先, III-V 半导体底层被一根低精力的离子横梁在提高的温度照耀,形成由一个反向的取向附生过程由于的一个高度订的 nanogroove 模式表面空缺自己组装。第二,多样的金属性的 nanowire 穿(Au, Fe, Ni,公司, FeAl 合金) 被免职在一个看一眼的发生角度在这些 III-V 模板上制作。这个方法允许有频率的数组击倒到 45 nm 的金属性的 nanowire 的制造可伸缩直到晶片尺寸制造。作为典型高贵、磁性的金属,这里生产的 Au 和 Fe nanowire 数组展出了大各向异性光并且磁性分别地。Au nanowire 数组的局部性的表面电浆子回声(LSPR ) 的刺激导致了高电场改进,它被用来在散布的提高表面的拉曼(重量的单位) 检测酞毒(CoPc ) 。而且, Fe nanowire 数组显示出一架很高的在里面飞机约 412 mT 的磁性的 anisotropy,它磁性的 anisotropy 还回答的最大的在里面飞机可以被报导那完全在一部薄电影的飞机以内经由形状 anisotropy 被导致。 | Qi Jia Xin Ou Manuel Langer Benjamin Schreiber Jorg Grenzer Pablo F. Siles Raul D. Rodriguez Kai Huang Ye Yuan Alireza Heidarian Rene Hubner Tiangui You Wenjie Yu Kilian Lenz Jurgen Lindner Xi Wang Stefan Facsko | 2018 | Nano Research2018，11，7： | 0 |
| 11 | Prognostic value of the RNA editing enzyme: ADAR1, and its association with immune cells infiltration in pancreatic adenocarcinoma显示文摘The adenosine deaminase acting on RNA(ADAR)protein family was well characterized as RNA editing enzymes converting adenosines to inosines(A-to-l)in dsRNA structures.They share a homologous structure including the dsRNA-binding domain and the deaminase domain.ADAR1 function as the primary editing enzyme for A-to-l mutation because of its higher and ubiquitous expression compared to ADAR2 and ADAR3 in eukaryotes. | Jialong Qi You Zhou Zhikai Zhu Chuanshan Xu Wenjie Chen | 2023 | Genes & Diseases2023，10，1： | 0 |
| 12 | Dihydromyricetin‑Incorporated Multilayer Nanofibers Accelerate Chronic Wound Healing by Remodeling the Harsh Wound Microenvironment显示文摘The harsh microenvironment in wound(HMW)remains a major obstacle to chronic wound healing.Although a series of bioactive materials have been developed,few of them are multi-functional and able to accelerate wound healing via precisely remodeling the HMW.Herein,a series of dihydromyricetin(DHM)-incorporated multilayer nanofibers(termed DQHP-n,n=0,2,6 and 10)are fabricated using a layer-by-layer(LBL)self-assembly technique.The average diameters of DQHP-n significantly increase from 0.30±0.16μm to 0.84±0.28μm(P<0.05)along with the n value increased from 0 to 10,the tensile strength of that is also significantly improved from 1.12±0.15 MPa to 2.16±0.30 MPa(P<0.05),and the water contact angle of that significantly decreases from 129.1±1.5°to 76.6±3.9°(P<0.05).The DQHP-n are found to be biocompatible,in which DQHP-6 promoted cell migration through activation of the epithelial–mesenchymal transformation(EMT)pathway and reconstruction of the HMW by stopping bleeding,killing bacteria,eliminating inflammation,and scavenging reactive oxygen species(ROS).The in vivo evaluation is carried out via an E.coli-infected rat skin regeneration model.The DQHP-6 group demonstrates the best effect,as it healed up to 98.5±1.0%of the wound area at day 15.DQHP-6 differentially regulates the mRNA expressions of several cytokines(FGF2,PDGF,IL-1α,IL-6,IL10,and TGF-β),which ends to reductions of total inflammatory cells(CD45^(+) cells)and M1 macrophages(CD80^(+) and CD86^(+) cells),proliferation of host cell(Ki67^(+) cells),and enhancement of collagen synthesis.In conclusion,DQHP-6 exhibits multifunctional properties for HMW,and can serve as a promising wound dressing for clinical transformation. | Zijian Wang Wenjie You Wang Wang Weiqun Tian Fangjin Chen Yu Xiao Yun Chen Xinghuan Wang | 2022 | Advanced Fiber Materials2022，4，6： | 0 |
| 13 | Investigation of pressure drop in flexible ventilation ducts under different compression ratios and bending angles显示文摘Due to the large degree of freedom in terms of design and installation, flexible ventilation ducts are commonly used in ventilation systems. However, excessive use of flexible ducts may lead to greater pressure drop and higher energy consumption. This study conducted experimental measurements to characterize the pressure drop in flexible ventilation ducts with different compression ratios and bending angles. This investigation first measured the pressure drop in straight flexible ducts with four compression ratios under various airflow rates. The calculated friction factor for the straight flexible ducts was negatively associated with the compression ratio. Next, the pressure drops in single-bend flexible ducts with various bending angles from 30° to 150° were measured under various airflow rates. The calculated loss coefficient of the bend increased with the bending angle for single-bend flexible ducts. Finally, the influence of the intermediate duct length on the pressure drop across two bends was experimentally investigated. When the length of the intermediate duct was greater than eight times the inner diameter, the pressure drop across a double-bend flexible duct could be calculated from the friction factors and loss coefficients with a relative error less than 1%. The data obtained in this study can be used to calculate the total pressure loss in flexible ventilation ducting systems in buildings. | Ho Kam Dai Wenjie Huang Liye Fu Chao-Hsin Lin Daniel Wei Zhongzhe Dong Ruoyu You Chun Chen | 2021 | Building Simulation2021，14，4： | 0 |
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