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| 1 | 152 W high-power blue diode laser operated at 447 nm显示文摘We demonstrate a high-power blue diode laser operated at 447 nm combining laser diodes using an optical fiber bundle. As many as 127 diode lasers at 447 nm were coupled into 400 μm/0.22 NA fibers using an aspherical lens group with different focus lengths. The bare fibers were mechanically bundled through high temperature ultraviolet adhesive after the coatings of the 127 fibers were stripped. The diameter of the fiber bundle was 6 mm. The total output power of such a bundle was 152 W with electro-optical conversion efficiency of 27.56%and the RMS power instability was less than ±1% within 3 h. | Peng Wu Ling Zhang Haijuan Yu Xiandan Yuan Zhiyan Zhang Pengfei Zhao Shuzhen Zou Chaojian He Yaoyao Qi Yingying Yang Gang Li Xubao Wang Xuechun Lin | 2017 | Journal of Semiconductors2017，38，7： | 4 |
| 2 | Targeting integrin pathways:mechanisms and advances in therapy显示文摘Integrins are considered the main cell-adhesion transmembrane receptors that play multifaceted roles as extracellular matrix(ECM)-cytoskeletal linkers and transducers in biochemical and mechanical signals between cells and their environment in a wide range of states in health and diseases.Integrin functions are dependable on a delicate balance between active and inactive status via multiple mechanisms,including protein-protein interactions,conformational changes,and trafficking.Due to their exposure on the cell surface and sensitivity to the molecular blockade,integrins have been investigated as pharmacological targets for nearly 40 years,but given the complexity of integrins and sometimes opposite characteristics,targeting integrin therapeutics has been a challenge.To date,only seven drugs targeting integrins have been successfully marketed,including abciximab,eptifibatide,tirofiban,natalizumab,vedolizumab,lifitegrast,and carotegrast.Currently,there are approximately 90 kinds of integrin-based therapeutic drugs or imaging agents in clinical studies,including small molecules,antibodies,synthetic mimic peptides,antibody-drug conjugates(ADCs),chimeric antigen receptor(CAR)T-cell therapy,imaging agents,etc.A serious lesson from past integrin drug discovery and research efforts is that successes rely on both a deep understanding of integrin-regulatory mechanisms and unmet clinical needs.Herein,we provide a systematic and complete review of all integrin family members and integrin-mediated downstream signal transduction to highlight ongoing efforts to develop new therapies/diagnoses from bench to clinic.In addition,we further discuss the trend of drug development,how to improve the success rate of clinical trials targeting integrin therapies,and the key points for clinical research,basic research,and translational research. | Xiaocong Pang Xu He Zhiwei Qiu Hanxu Zhang Ran Xie Zhiyan Liu Yanlun Gu Nan Zhao Qian Xiang Yimin Cui | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 3 |
| 3 | Design and anti-sway performance testing of pesticide tanks in spraying UAVs显示文摘Anti-sway performance is one of the most important factors that affect the stability of unmanned aerial vehicles(UAVs).In this study,an anti-sway performance testing method and an evaluation formula for pesticide tanks were developed,which could facilitate the design and application of pesticide tank.The detection device mainly comprises a testing stand,a mounting and testing part,and a driving and control part.In the testing method,P(maximum pressure)measured by a barometer and t(fluctuation recovery time)measured by a high-speed camera were used as evaluation indexes.With the aim to determine the optimal position of the pressure detection device and the optimal filling ratio,four representative pesticide tanks were involved in this study.The results showed that the optimal position of the pressure detection device was at the middle position on the tank wall,halfway up from the bottom,and the optimal filling ratio was 0.8.Using P and t as evaluation indexes,a comprehensive evaluation formula was developed based on these tests:S=0.7Pi+0.3ti.Anti-sway performance of pesticide tanks was evaluated by a comprehensive score.A disk pesticide tank with a baffle was determined to be the best among the four types of pesticide tanks,showing a score of 1.The scores of the other three pesticide tanks were 0.500,0.428 and 0.612,respectively.These results indicated that the baffle structure in the pesticide tank and the radian design of the tank wall can effectively improve the anti-sway performance of a pesticide tank.The proposed detection device and test method are simpler and more intuitive compared to other approaches in evaluating the anti-sway performance of pesticide tanks in spraying UAVs,and they can be used as a reference to guide the design of pesticide tanks and the stability evaluation of spraying UAVs. | Yu Zang Ying Zang Zhiyan Zhou Xiuyan Gu Rui Jiang Lingxi Kong Xingang He Xiwen Luo Yubin Lan | 2019 | International Journal of Agricultural and Biological Engineering2019，12，1： | 2 |
| 4 | The effect of copper valence on catalytic combustion of styrene over the copper based catalysts in the absence and presence of water vapor显示文摘Catalysts Cu Ox/γ-Al_2O_3-IH and Cu Ox/γ-Al_2O_3-IM were prepared, characterized, and tested for styrene combustion in the absence and presence of water vapor. The effect of copper valence of the catalysts on the catalytic activity for styrene combustion was discussed using the theory of hard soft acids and bases(HSAB).The results showed that the existence of water vapor in feed stream inhibited the catalytic activity for styrene combustion due to the competition adsorption of water molecule. HSAB theory confirmed that the local soft acidity of the catalyst Cu Ox/γ-Al_2O_3-IH was much stronger than that of the catalyst Cu Ox/γ-Al_2O_3-IM because of the higher content of soft acid Cu+on its surface, which increased the adsorption ability toward soft base of styrene and reduced the adsorption toward hard base of water vapor, and thus increased the catalytic activity for styrene combustion and weakened the negative influence of water vapor. | Hongyan Pan Zhiyan He Qian Lin Fei Liu Zhong Li | 2016 | Chinese Journal of Chemical Engineering2016，24，4： | 1 |
| 5 | Oxygen-rich carbon-nitrogen quantum dots as cocatalysts for enhanced photocatalytic H_2 production activity of TiO_2 nanofibers显示文摘We developed an one-step hydrothermal method to synthesize carbon-nitrogen quantum dots(CNQDs) with oxygen-rich functional groups.The sample was characterized by TEM,AFM,FT-IR,XPS,UV-vis absorption and PL spectra.The 0/C and N/C atomic ratio of typical CNQDs with diameters of 3-6 nm are ca.0.4 and 0.2,respectively.Without noble metal cocatalyst,the photocatalytic H_2 production rate of CNQDs/TiO_2 nanofibers(NFs)(112.4 μmol h^(-1) g^(-1)) is 1.8 times higher than that of TiO_2 NFs.The good absorption of light contributes to the enhanced photocatalytic H_2 performance.The CNQDs could be promising in biomedical imaging,optical data recording storage and photo/electrocatalysis,etc. | Zhiyan Chen Yishang Wu Qichen Wang Zhiyong Wang Lihua He Yongpeng Lei Zhongmin Wang | 2017 | Progress in Natural Science:Materials International2017，27，3： | 1 |
| 6 | luxS mutant regulation: quorum sensing impairment or methylation disorder?显示文摘 | WANG Qian HE Zhiyan HU Yuejian | 2012 | Sensors2012，12，： | 1 |
| 7 | Role of the warming trend in global land surface air temperature variations显示文摘Global warming and its climatic and environmental effects have mainly been investigated in terms of the absolute warming rate.Little attention has been paid to the contribution of absolute warming rate to variability on various time scales of surface air temperature(SAT),which may be a more direct index for measuring the ecoclimatic effect of warming trend.The present study analyzed the role of secular warming trend in the variations of global land SAT for 1901–2016.Less than one-third of annual SAT variations were contributed by the warming trend over large parts of the globe generally.The ratios were up to two-thirds over eastern South America,parts of South Africa and the regions around the southwestern Mediterranean and Sunda islands where the absolute warming rate was moderate but the endemic species were undergoing exceptional loss of habitat.The ratios also exhibited smallest seasonal difference over these regions.Therefore,the ratio of the warming trend to the SAT variations may be a better measure compared to the absolute warming rate for the local ecoclimate.We should also pay more attention to the regions with high ratio,not only the regions with the high absolute warming rate. | Zhiyan ZUO Dong XIAO Qiong HE | 2021 | Science China Earth Sciences2021，64，6： | 1 |
| 8 | Electrochemical and biological performance of hierarchical platinum-iridium electrodes structured by a femtosecond laser显示文摘Neural electrode interfaces are essential to the stimulation safety and recording quality of various bioelectronic therapies.The recently proposed hierarchical platinum-iridium(Pt-Ir)electrodes produced by femtosecond lasers have exhibited superior electrochemical performance in vitro,but their in vivo performance is still unclear.In this study,we explored the electrochemical performance,biological response,and tissue adhesion of hierarchical Pt-Ir electrodes by implantation in adult rat brains for 1,8,and 16 weeks.Regular smooth Pt-Ir electrodes were used as a control.The results showed that the electrochemical performance of both electrodes decreased and leveled off during implantation.However,after 16 weeks,the charge storage capacity of hierarchical electrodes stabilized at~16.8 mC/cm^(2),which was 15 times that of the smooth control electrodes(1.1 mC/cm^(2)).Moreover,the highly structured electrodes had lower impedance amplitude and cutoff frequency values.The similar histological response to smooth electrodes indicated good biocompatibility of the hierarchically structured Pt-Ir electrodes.Given their superior in vivo performance,the femtosecond laser-treated Pt-Ir electrode showed great potential for neuromodulation applications. | Linze Li Changqing Jiang Wanru Duan Zhiyan Wang Feng Zhang Changgeng He Tiangang Long Luming Li | 2022 | Microsystems & Nanoengineering2022，8，5： | 1 |
| 9 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 10 | Test and evaluation method for endurance performance of electric multi-rotors spraying drones显示文摘The endurance performance(EP)of electric multi-rotors spraying drones(EMSDs)is a key technical indicator that ensures the completion of tasks and improves their usefulness.To improve the EP of current EMSD,a test system was designed to determine the EP based on the EMSD test platform,and the performance evaluation method was studied.Firstly,a test model was established to determine the equivalent energy dissipation using the performance-testing platform of the EMSD.Secondly,a multisensory test system was constructed.An attitude sensor,high-power DC power supply,infrared thermal imager,and serial port server were selected.The mounting fixture was designed to meet the universal mounting requirements of drone.In addition,the software LabVIEW was employed to program the code for the controller and the host computer,where functions such as data collection,data processing,communication,and graphical user interface(GUI),were performed reliably in real time.Thirdly,the test method was explored by considering factors such as the power consumption,thermal efficiency ratio,and unit load power consumption rate.In particular,a comprehensive index method and expert consultation weight method were used to evaluate the EP of the EMSD with multiple indexes.Finally,a systematic real-machine test was carried out on the three types of drones that are currently widely used in the market.The results verified the effectiveness and feasibility of the proposed method,which was employed to test and evaluate the EP based on the EMSD performance testing platform.At the same time,it can provide a reference for the development of the EMSD. | Rui Ming Zhiyan Zhou Xiwen Luo Yubin Lan Xingang He Cancan Song Rui Jiang Luhong Tian Shahbaz Gul Hassan | 2019 | International Journal of Agricultural and Biological Engineering2019，12，2： | 0 |
| 11 | Design and test of centrifugal disc type sowing device for unmanned helicopter显示文摘In China,it is difficult for manned aircraft to sow seeds in small and scattered plots,especially in areas including hills,swamps,telegraph poles,windbreaks,and residential areas;in such terrain,the sowing machinery cannot function properly.However,unmanned helicopters(UHs)are flexible enough to control and adapt to the complex environments that are not easily accessible by terrain sowing machinery and large agricultural aircraft,which have been widely used in agriculture.In this study,a centrifugal disc-type sowing device for an unmanned helicopter(CDTSDUH)was designed.The factors influencing the seed velocity when the seeds move away from the disc were explored by analyzing the forces of the seed acting on the sowing disc and the wind field of the UHs.The influential factors include the distance from the falling mouth to the center of the disc,the offset angle of the falling mouth,and the rotation speed of the disc.An orthogonal test was designed with the sowing width and the curvature of the sowing area as the indexes.The test results showed that the three factors mentioned above had a greater impact on the sowing width than the curvature of the seeding area.Moreover,the superior parameters of the disc were determined.It was also suggested that the above factor levels had little effect on the offset width of sowing.The results of the test conducted for studying the sowing uniformity of the CDTSDUH indicated that the maximum and minimum difference values among the number of particles of the sampling points in the forward direction was 11 and 8,and the coefficient of variation of the number of particles in each row was more than 20%,indicating less uniformity was achieved when sowing in the lateral(perpendicular to the forward direction)direction,as compared to that in the forward direction.This study determined the ideal values for the radius of particles position,the offsetting angle,and the disc speed of the sowing machinery designed.Furthermore,considering that there are so many factors that influence the manner in which a UH functions,more analysis results and test data of influencing factors need to be acquired by experiments.The uniformity of sowing needs to be further improved.The results provided some theoretical and experimental references for the technology research on the centrifugal disc-type sowing device for UHs. | Cancan Song Zhiyan Zhou Xiwen Luo Yubin Lan Xingang He Rui Ming Keliang Li Shahbaz Gul Hassan | 2018 | International Journal of Agricultural and Biological Engineering2018，11，2： | 0 |
| 12 | Study on acrylic transmittance for JUNO Central Detector显示文摘Background The Central Detector(CD)of the Jiangmen Underground Neutrino Observatory(JUNO)uses 20,000 tons of liquid scintillator as target mass,and the design value of energy resolution of neutrino is 3%at 1 meV.Acrylic transmittance is an important parameter for CD in order to maximize the detection of scintillating photons.Motivation The composition and processing techniques of acrylic can surely affect its transmittance.How the composition,thermoforming temperature,heat preservation time and surface treatment process of acrylic affect its transmittance was measured and analyzed.Methods According to these studies,JUNO determined its special acrylic composition and processing techniques:no components of plasticizer or anti-UV in the composition,decreasing the time span and temperature during the demolding of flat panel,and adopting suitable thermoforming temperature of spherical panel.Results Finally,the preproduction of spherical acrylic panels meets the JUNO requirement confirming a transmittance in ultrapure water greater than 96%at the wavelength of 420 nm. | Xiaoyu Yang Nan Li Yuekun Heng Xiaohui Qian Xiaoyan Ma Yuesheng Tang Jianxia Xiao Gaofeng Zhang Wei Cheng Hongbing Song Mengzhao Li Zhiyan Cai Kaixi Huang Zhi Wu Wei He Yatian Pei | 2021 | Radiation Detection Technology and Methods2021，5，2： | 0 |
| 13 | Thermal reliability analysis of the central detector of JUNO显示文摘Introduction The Jiangmen Underground Neutrino Observatory(JUNO)is a multipurpose neutrino experiment designed to determine neutrino mass hierarchy,precisely measure oscillation parameters and study solar neutrinos,supernova neutrinos and geo-neutrinos,etc.The central detector(CD)of JUNO has 20,000 tons liquid scintillator as target mass,which contains inside a huge acrylic sphere with inner diameter of 35.4 m,supported by a stainless steel structure.The whole structure of CD will be installed inside a cylindrical water pool,and the acrylic sphere will be submerged in the center of water pool.The operating temperature of CD is designed to be 21℃ as long as over 20 years,which is determined by the mechanical requirement of the structure and physics consideration.Methods For this operating temperature,a special cooling system will be used to maintain the temperature inside the water pool.The main structure of CD is composed of acrylic and stainless steel,and they have much different thermal expansion coefficients,strengths and life times.Change in temperature may affect the safety of CD.As part of reliability analysis,the effect of cooling system failure on the CD is considered,and finite element method is used in our thermal calculation.In this article,the temperature fields before and after cooling system failure are calculated and analyzed,and the temperatures of different locations of water pool after cooling system failure are compared and discussed in detail. | Xiaoyu Yang Yuekun Heng Xiaoyan Ma Wei He Huafeng Li Kaixi Huang Tao Song Jiajie Ling Zhi Wu Xiao Tang Xiaolan Luo Xiaohui Qian Yatian Pei Nan Li Fengjiao Luo Zhiyan Cai Mengzhao Li | 2019 | Radiation Detection Technology and Methods2019，3，4： | 0 |
| 14 | Constructing bimodal nanoprobe based on Gd:AgInS_(2)/ZnS quantum dots for fluorometric/magnetic resonance imaging in mesenchymal stem cells显示文摘Mesenchymal stem cells(MSCs)hold great promise in regenerative medicine and received overwhelm-ing concerns to promote their therapeutic effects.Owing to the shortage of MSCs-specific biomarkers,bimodal imaging nanoprobes with integrated complementary information are of great importance in ameliorating the efficacy of MSCs terminal tracking.In this study,a noninvasive dual-mode imaging nanoprobe with enhanced detection sensitivity and spatial resolution based on alloyed Gd:AgInS_(2)/ZnS quantum dots(QDs)was first fabricated through a microwave-assisted heating method.The QDs with red emissive fluorescence exhibit excellent biocompatibility in MSCs under a confocal microscope.As for magnetic resonance imaging(MRI),the longitudinal relaxation rate of 11.1420 mM^(-1) S^(-1) of Gd:AgInS_(2)/ZnS QDs was achieved,which was 1.7 times higher than that of commercial MRI contrast agent(6.4667 mM^(-1) S^(-1)).Furthermore,the cellular internalization of Gd:AgInS_(2)/ZnS QDs exerts no significant effect on the adipogenesis of MSCs and is conducive to the observation of further adipogenic differentiation.Our work helps to verify the promising prospect to develop a bimodal nanoprobe of fluorescence/MRI based on Gd:AgInS_(2)/ZnS QDs,which could monitor the differentiation and migration of MSCs for further therapeu-tic approach. | Dan Yang Xian Wei Zhiyan Piao Zhongjie Cui Haiyang He Zhuoqi Wen Wanlu Zhang Le Wang Shiliang Mei Ruiqian Guo | 2023 | Journal of Materials Science & Technology2023，，17： | 0 |
| 15 | Laser measurement system for acrylic transmittance of JUNO central detector显示文摘Background During the research phase of acrylic panel for the Jiangmen Underground Neutrino Observatory(JUNO)central detector(CD),the darkroom transmittance measurement system(DTMS)was designed and built,and a massive amount of measurements were carried out to help determine the composition and processing techniques of the acrylic panel.Motivation The mass production of acrylic panels was started after the pilot production.The requirement of transmittance measurement put forward new demands on operation,and a new measurement system was considered to support removable and non-destructive measurement on site.Result After the accomplishment of design,development and verification were completed,the laser measurement system came into use in the acrylic workshop of Taixing Donchamp Acrylic Ltd,and the transmittance results of acrylic spherical panels met the requirement of JUNO.The optical design,tooling design,data processing interface and uncertainty analyses of the laser measurement system are discussed in detail,and the measured transmittance results are also introduced in this article. | Zhaohan Li Xiaoyu Yang Yuekun Heng Xiaoyan Ma Xiaohui Qian Kaixi Huang Zhi Wu Wei He Meihang Xu Xiaolan Luo Yatian Pei Mengzhao Li Zhiyan Cai Wenlu Wei Yifang Wang | 2021 | Radiation Detection Technology and Methods2021，5，3： | 0 |
| 16 | Development of UAV-based shot seeding device for rice planting显示文摘In order to realize the high-quality row seeding operation with unmanned aerial vehicle(UAV)in paddy field,a shot seeding device that can sow five rows of pelleted rice seeds at the same time was designed.The shot seeding device mainly consists of an external grooved wheel seed metering device and five shot seeding modules.The designed external grooved wheel seed metering device can take the seeds out of the seed box and divide the seeds into five parts.The shot seeding module can accelerate the pelleted rice seeds to reduce the impact of the UAV wind on the direction of seed movement.Furthermore,an angle adjustment mechanism for the shot seeding module was used to change the row spacing.The seed metering device test verified that when the speed of the seed metering wheel was 15 r/min,the coefficient of variation of the discharge rate of each row(C.V1)and total seed discharge rate stability(C.V2)were 1.70%and 1.04%,respectively.Image processing technique was used to test the UAV seeding performance.The distribution characteristics of seeds on the ground showed that the number of seeds in each row gradually increased from both sides to the middle in the width direction.According to the statistics,there were 60%-70%of the seeds in each row in the 100 mm width range.The field test showed that when the working height was 1.5 m and the seeding quantity was 38.56 kg/hm^(2),the performance of sowing in rows was obvious,the deviation rate of seeding quantity was 1.89%.After 16 d of sowing,the seeds’emergence rate was stable,and the average emergence rate was 82.63%and the yield was 6775.50 kg/hm^(2). | Wei Liu Shuaishuai Zou Xuelang Xu Qingyu Gu Weizhuo He Jun Huang Junhao Huang Zichen Lyu Jianqin Lin Zhiyan Zhou Rui Jiang Xiwen Luo | 2022 | International Journal of Agricultural and Biological Engineering2022，15，6： | 0 |
| 17 | In vitro model of the glial scar显示文摘The trauma of central nervous system(CNS)can lead to glial scar,and it can limit the regeneration of neurons at the injured area,which is considered to be a major factor affecting the functional recovery of patients with CNS injury.At present,the study of the glial scar model in vitro is still limited to two-dimensional culture,and the state of the scar in vivo cannot be well mimicked.Therefore,we use a collagen gel and astrocytes to construct a three-dimensional(3D)model in vitro to mimic natural glial scar tissue.The effects of concentration changes of astrocytes on cell morphology,proliferation,and tissue performance were investigated.After 8 days of culture in vitro,the results showed that the tissue model contracted,with a measured shrinkage rate of 4.5%,and the compressive elastic modulus increased to nearly 4 times.Moreover,the astrocytes of the 3D tissue model have the ability of proliferation,hyperplasia,and formation of scar clusters.It indicates that the model we constructed has the characteristics of glial scar tissue to some extent and can provide an in vitro model for the research of glial scar and brain diseases. | Ao Fang Zhiyan Hao Ling Wang Dichen Li Jiankang He Lin Gao Xinggang Mao Rubén Paz | 2019 | International Journal of Bioprinting2019，5，2： | 0 |
| 18 | Correlation between clinical course and radiographic development on CT scan in patients with COVID-19显示文摘Background:To analyze the correlation between clinical course and radiographic development on computed tomography(CT)in patients with confirmed coronavirus disease 2019(COVID-19)and to provide more evidence for treatment.Methods:This retrospective,observational,cohort study enrolled 49 patients with Reverse transcription-polymerase chain reaction(RT-PCR)-confirmed COVID-19,which included 30 patients admitted to the intensive care unit(ICU)of Wuhan Third Hospital and 19 patients either admitted to or receiving telemedicine consultation from Shanghai General Hospital,Shanghai Xuhui Dahua Hospital,and hospitals in other provinces.CT scans were performed in all enrolled patients and the radiographic features including simple ground-glass opacities(GGOs),GGO with interlobular septal thickening,consolidations with GGO,and consolidations only were monitored by repeating the CT.The progression of these radiographic features was analyzed in combination with their clinical staging and the time interval between onset of symptoms to CT.Results:Based on illness severity,the 49 patients were classified into four stages:mild(n=6),moderate(n=12),severe(n=16),and critically ill(n=15).The CT findings were classified into three phases:early(n=5),progres-sion(n=39),and recovery(n=5).Among the 49 patients,9 had bilateral diffuse GGO or diffuse consolidations(white lungs)and were counted as 18 lesions.Three patients had no abnormal findings on initial CT,but their repeat CT showed new lesions.In all,we identified 892 lesions including simple GGO,GGO with interlobular septal thickening,consolidations with GGO,and consolidations only.Conclusions:Most patients had pulmonary lesions on the posterior,inferior,and peripheral lung fields on CT.The development of GGO with interlobular septal thickening,GGO with consolidations,and consolidations only happened mainly between day 8 and 14.The emergence of consolidations may suggest the progression to the severe phase of the illness,whereas simple consolidations or“white lung”may suggest a critically ill phase. | Yun Xie Luyu Yang Hui Dong Song Cao Wenkai Zhang Qiong Chen Baoliang Jin Zhiguo Zhou Jun Liu Zhiyan He Ruilan Wang | 2021 | Journal of Intensive Medicine2021，1，1： | 0 |
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